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1. 发明申请

US20080119411A1 ORALLY ADMINISTERING PARATHYROID HORMONE AND CALCITONIN 有权
公开(公告)号：US20080119411A1
公开(公告)日：2008-05-22
申请号：US12020700
申请日：2008-01-28
申请人： Joseph Ault , Moise Azria , Simon Bateman , James McLeod
发明人： Joseph Ault , Moise Azria , Simon Bateman , James McLeod
IPC分类号： A61K38/29 , A61K38/23 , C07K14/635
CPC分类号： A61K47/183 , A61K38/23 , A61K38/29 , A61K2300/00
摘要： A method for orally administering a parathyroid hormone, PTH, comprising orally co-administering to a patient in need of PTH an effective amount of a PTH and an effective amount of calcitonin. The method according to the invention allows for the oral administration of PTH without the hypercalcemia, hypercalcuria and nephrolithiasis side effects.
摘要翻译：一种口服甲状旁腺激素PTH的方法，其包括向需要PTH的患者口服共同施用有效量的PTH和有效量的降钙素。根据本发明的方法允许口服给予PTH而没有高钙血症，高钙血症和肾结石病副作用。

2. 发明申请

US20070232524A1 Oral administration of calcitonin 有权
标题翻译：口服降钙素
公开(公告)号：US20070232524A1
公开(公告)日：2007-10-04
申请号：US11805748
申请日：2007-05-24
申请人： Moise Azria , Simon Bateman , James McLeod
发明人： Moise Azria , Simon Bateman , James McLeod
IPC分类号： A61K38/00 , C07K14/585
CPC分类号： A61K31/195 , A61K9/19 , A61K9/2013 , A61K9/2027 , A61K38/23 , A61K47/183
摘要： Disclosed is a particular method of orally administering pharmaceutical compositions comprising calcitonin in combination with oral delivery agents, prior to the consumption of food in humans, and a method of treatment of disorders responsive to the action of calcitonin employing such method of administration; also oral calcitonin pharmaceutical compositions with particular ratios of the amount of oral delivery agent to the amount of calcitonin.
摘要翻译：公开了在食用人类之前口服给药药物组合物的方法，所述方法包括降钙素与口服递送剂的组合，以及使用这种施用方法对降钙素作用起反应的病症的治疗方法; 还有口服降钙素药物组合物，其具有特定比例的口服递送剂与降钙素的量。

3. 发明申请

US20060135402A1 Oral administration of calcitonin 审中-公开
公开(公告)号：US20060135402A1
公开(公告)日：2006-06-22
申请号：US10523421
申请日：2003-07-31
申请人： Moise Azria , Simon Bateman , James McLeod
发明人： Moise Azria , Simon Bateman , James McLeod
IPC分类号： A61K38/23 , A61K31/195
CPC分类号： A61K31/195 , A61K9/19 , A61K9/2013 , A61K9/2027 , A61K38/23 , A61K47/183
摘要： Disclosed is a particular method of orally administering pharmaceutical compositions comprising calcitonin in combination with oral delivery agents, prior to the consumption of food in humans, and a method of treatment of disorders responsive to the action of calcitonin employing such method of administration; also oral calcitonin pharmaceutical compositions with particular ratios of the amount of oral delivery agent to the amount of calcitonin.

4. 发明申请

US20070287664A1 Combinations of HCV protease inhibitor(s) and CYP3A4 inhibitor(s), and methods of treatment related thereto 审中-公开
标题翻译： HCV蛋白酶抑制剂和CYP3A4抑制剂的组合以及与之相关的治疗方法
公开(公告)号：US20070287664A1
公开(公告)日：2007-12-13
申请号：US11725518
申请日：2007-03-19
申请人： Robert Ralston , Julie Strizki , Jaromir Vlach , Samir Gupta , Edward O'Mara , Anima Ghosal , Michelle Treitel , James McLeod , Ronald White
发明人： Robert Ralston , Julie Strizki , Jaromir Vlach , Samir Gupta , Edward O'Mara , Anima Ghosal , Michelle Treitel , James McLeod , Ronald White
IPC分类号： A61K38/12 , A61K31/44 , A61P31/00 , C07D221/02
CPC分类号： A61K31/496 , A61K31/16 , A61K31/192 , A61K31/395 , A61K31/40 , A61K31/403 , A61K31/427 , A61K31/4965 , A61K38/07 , A61K45/06 , A61K2300/00
摘要： Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations comprising, separately or together: (a) a CYP3A4 inhibitor; and (b) a HCV protease inhibitor; for concurrent or consecutive administration in treating a human subject infected with HCV.
摘要翻译：公开了药物，药物组合物，药物试剂盒和基于组合的方法，所述组合包括，单独或一起：（a）CYP3A4抑制剂; 和（b）HCV蛋白酶抑制剂; 用于同时或连续给药以治疗感染HCV的人类受试者。

5. 发明授权

US5478184A Conveyor system for rod-like articles 失效
标题翻译：棒状物品输送系统
公开(公告)号：US5478184A
公开(公告)日：1995-12-26
申请号：US979339
申请日：1992-11-20
申请人： Leonard J. Bryant , Peter A. Clarke , Wilfred B. Heginbotham , Keith K. Martin , James McLeod
发明人： Leonard J. Bryant , Peter A. Clarke , Wilfred B. Heginbotham , Keith K. Martin , James McLeod
IPC分类号： A24C5/352 , B65G47/50 , B65G1/18
CPC分类号： B65G47/50 , A24C5/352
摘要： Containers for rod-like articles are provided with a device, e.g. a transponder, capable of carrying variable coded information. Read and write devices are provided at appropriate positions, e.g. tray fillers and unloaders, to ensure that only containers of the correct type and contents are passed for further processing. The coded information may also relate to time of manufacture or loading, particularly where the articles are filter rods, to ensure unloading of only those containers in which the rods have received adequate curing time. A buffer reservoir system having a tray filler, tray unloader, and a tray handling system includes a transfer member capable of transferring trays between different positions of the tray handling system and a static trolly. The transfer member may comprise a robotic or other programmable member.
摘要翻译：用于棒状制品的容器设置有装置，例如一个应答器，能承载可变编码信息。在适当的位置提供读写设备，例如。托盘填料和卸料机，以确保只有正确类型和内容物的容器才能通过进一步加工。编码信息还可以涉及制造或装载的时间，特别是在物品是过滤杆的情况下，以确保只有那些容纳有棒已经接收足够固化时间的容器才能卸载。具有托盘填充物，托盘卸载机和托盘处理系统的缓冲储存器系统包括能够在托盘处理系统的不同位置和静态拖拉之间传送托盘的转印构件。传送构件可以包括机器人或其他可编程构件。

6. 发明申请

US20070041818A1 Collection of lumber pieces from the ground 审中-公开
标题翻译：从地面收集木材
公开(公告)号：US20070041818A1
公开(公告)日：2007-02-22
申请号：US11437870
申请日：2006-05-22
申请人： James McLeod , Murray Pisony
发明人： James McLeod , Murray Pisony
IPC分类号： B60P1/00
CPC分类号： B65G65/06 , B65G57/186 , B65G2201/0217
摘要： An apparatus for picking lumber pieces from the ground for example for removing support lumber used during laying of a pipe line comprises a tracked vehicle to which is attached a frame carrying a transport conveyer along the side of the vehicle inclined forwardly and downwardly toward the ground. A picking assembly is provided at the front of the conveyor and alongside the vehicle for lifting the pieces. This includes a front picking roller and a movable outer side blade which is inclined outwardly to the outer side of the picking roller and can be pivoted inwardly to close around the front of the picking roller to squeeze the lumber pieces to force them onto the conveyor.
摘要翻译：用于从地面拾取木材件的装置，例如用于去除在铺设管线期间使用的支撑木材，包括跟踪车辆，其沿着车辆侧面承载运输输送机的框架向前和向下朝向地面倾斜。在输送机的前部并且与车辆一起设置拾取组件以用于提升件。这包括前拾取辊和可移动的外侧叶片，其向外倾斜到拾取辊的外侧，并且可以向内枢转以围绕拾取辊的前部关闭，以挤压木材件以将其推到输送机上。

7. 发明申请

US20050132667A1 Collection and stacking of lumber pieces from the ground 有权
标题翻译：从地面收集和堆放木材
公开(公告)号：US20050132667A1
公开(公告)日：2005-06-23
申请号：US10969238
申请日：2004-10-21
申请人： James McLeod , Murray Pisony
发明人： James McLeod , Murray Pisony
IPC分类号： B65G57/18 , B65G65/06 , B65B35/30 , B65B35/50
CPC分类号： B65G65/06 , B65G57/186 , B65G2201/0217
摘要： An apparatus for picking, conveying, stacking and bundling lumber pieces from the ground for example for removing stacked support lumber during laying of a pipe line comprises a tracked vehicle to which is attached a frame carrying a transport conveyer along the side of the vehicle forwardly and downwardly toward the ground. At the forward picking end is provided a picker roller for lifting the lumber pieces from the ground. On one side of the picker roller is provided a drive conveyer which is generally vertical and operable in forward and reverse direction to orient the pieces. On the side opposite to the drive conveyers provided a vertical blade with a rearwardly inclined inner portion which blade can pivot inwardly to push the lumber pieces toward the drive conveyer and to enclose and squeeze the pieces to a position inward of the side of the conveyer. Behind the vehicle is mounted a stacking section which arranges the pieces in a row and then stacks part of the row on top of another part to form the stack. The stack passes through a frame which clamps the pieces together to squeeze the stack and also to wrap the stack with a strapping carried into place by a chain.
摘要翻译：用于拾取，输送，堆叠和捆扎来自地面的木材件的装置，例如用于在铺设管线期间移除堆叠的支撑木材包括跟踪车辆，其上沿着车辆侧向前方附接有承载运输输送机的框架，向下朝向地面。在向前拾取端设置有用于从地面提起木材件的拾取辊。在拾取辊的一侧设置有驱动输送机，其通常是垂直的并且可以在正向和反向方向上操作以使片材定向。在与驱动输送机相对的一侧设置有具有向后倾斜的内部部分的垂直叶片，该叶片可向内枢转以将木材块推向驱动输送机并且将该块包围并挤压到输送机侧面的位置。在车辆后方安装有堆叠部分，其将片排列成一行，然后将该行的一部分堆叠在另一部分的顶部上以形成堆叠。堆叠通过框架，该框架将这些块夹在一起以挤压堆叠，并且还通过链条将捆扎带运送到位。

8. 发明授权

US5190428A Conveyor system for rod-like articles 失效
标题翻译：棒状物品输送系统
公开(公告)号：US5190428A
公开(公告)日：1993-03-02
申请号：US475987
申请日：1990-02-06
申请人： Leonard J. Bryant , Peter A. Clarke , Wilfred B. Heginbotham , Keith K. Martin , James McLeod
发明人： Leonard J. Bryant , Peter A. Clarke , Wilfred B. Heginbotham , Keith K. Martin , James McLeod
IPC分类号： A24C5/352 , B65G47/50
CPC分类号： B65G47/50 , A24C5/352
摘要： Containers for rod-like articles are provided with a device, e.g. a transponder, capable of carrying variable coded information. Read and write devices are provided at appropriate positions, e.g. tray fillers and unloaders, to ensure that only containers of the correct type and contents are passed for further processing. The coded information may also relate to time of manufacture or loading, particularly where the articles are filter rods, to ensure unloading of only those containers in which the rods have received adequate curing time. A buffer reservoir system having a tray filler, tray unloader, and a tray handling system includes a transfer member capable of transferring trays between different positions of the tray handling system and a static trolley. The transfer member may comprise a robotic or other programmable member.
摘要翻译：用于棒状制品的容器设置有装置，例如一个应答器，能承载可变编码信息。在适当的位置提供读写设备，例如。托盘填料和卸料机，以确保只有正确类型和内容物的容器才能通过进一步加工。编码信息还可以涉及制造或装载的时间，特别是在物品是过滤杆的情况下，以确保只有那些容纳有棒已经接收足够固化时间的容器才能卸载。具有托盘填充物，托盘卸载机和托盘处理系统的缓冲储存器系统包括能够在托盘处理系统的不同位置和静态手推车之间传送托盘的传送构件。传送构件可以包括机器人或其他可编程构件。

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