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    • 7. 发明申请
    • METHOD OF SAMPLING AND/OR DEPOSITING A SAMPLE OF BIOLOGICAL MATTER AND DEVICE IMPLEMENTING SUCH A METHOD
    • 采样和/或沉积生物学样本的方法和实现方法的装置
    • US20130109047A1
    • 2013-05-02
    • US13808501
    • 2011-07-08
    • Jean-Philippe CharrierBruno ColinLaurent DrazekCécile ParisJean-Claude RaymondDominique Decaux
    • Jean-Philippe CharrierBruno ColinLaurent DrazekCécile ParisJean-Claude RaymondDominique Decaux
    • C12Q1/24
    • C12Q1/24C12M33/04
    • The aim of the present invention is a method of sampling all or part of a sample (11) of biological matter (7), which is crude, enriched or cultured through contact with a culture medium (8), such as agar, for example in a Petri dish, using a probe (3) equipped with a terminal end (4), said sampling method comprising the steps of cooling the terminal end (4) of the probe (3), sticking all or part of the sample (11) of biological matter (7) to be sampled through contact, or by applying a pressure exerted by the terminal end (4) onto the sample (11) of biological matter (7), and sampling of all or part of the sample (11) of biological matter (7) so as to separate the sample (11) of biological matter (7) from the culture medium (8), a method of depositing into a container (9) or onto an analysis plate (14) all or part of a sample (11) of biological matter (7) stuck onto a frosted terminal end (4) of a probe, said depositing method including a step of separating the terminal end (4) of the probe (3) from all or part of the sample (11) of biological matter (7), as well as a device (2), a kit and an apparatus (1) implementing these methods.
    • 本发明的目的是对生物物质(7)的全部或部分样品(11)进行取样的方法,其通过与诸如琼脂的培养基(8)接触而粗制,富集或培养。 在陪替氏培养皿中,使用配备有终端(4)的探针(3),所述取样方法包括冷却探针(3)的末端(4)的步骤,将全部或部分样品(11 ),或通过将终端(4)施加的压力施加到生物物质(7)的样品(11)上,并对样品(11)的全部或部分进行采样 )将生物物质(7)的样品(11)与培养基(8)分离,将沉积到容器(9)或分析板(14)中的全部或者 将生物物质(7)的样品(11)的一部分粘贴到探针的磨砂末端(4)上,所述沉积方法包括将所述末端(4) 来自生物物质(7)的全部或部分样品(11)的探针(3)以及实施这些方法的装置(2),试剂盒和装置(1)。
    • 8. 发明申请
    • Integrated Analysis Device Which Can Be Fitted To A Container Housing A Sample To Be Analyzed
    • 综合分析装置可以适用于集装箱住房要分析的样本
    • US20080152541A1
    • 2008-06-26
    • US11597867
    • 2005-06-24
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • G01N30/00B01J19/00G01N35/10
    • B01L3/505B01L2300/044B01L2300/0663B01L2300/0672B01L2300/0825B01L2400/0406Y10T436/110833Y10T436/112499
    • The present invention relates generally to the field of analysis, for example biological analysis. More specifically, the present invention relates to an analysis device (10, 40, 501, 60) designed to be associated with a container (22, 50, 70) containing a sample (28) to be analyzed, said device comprising essentially: a first impervious membrane (12, 42, 52, 62); a second impervious membrane (14, 44, 54, 64) superposed on the first membrane (12, 42, 52, 62); said first and second membranes being fixedly attached over at least a part of their surface, defining a peripheral zone, in order to define an interstitial space forming an internal reaction cavity (16, 46, 56, 66), with no means of fluid communication with the outside of said analysis device (10, 40, 501, 60); at least one analysis means (18, 47, 57, 67), placed inside said internal reaction cavity (16, 46, 56, 66), designed to be placed in contact with the sample (28); at least one means designed to create a way for the sample to enter said internal reaction cavity. The present invention also relates to a container (22, 50, 70) comprising such an analysis device.The present invention also relates to a method of analyzing a sample contained in a container, in which an analysis device according to the invention is used.
    • 本发明一般涉及分析领域,例如生物分析。 更具体地说,本发明涉及一种设计成与容纳待分析样品(28)的容器(22,50,70)相关联的分析装置(10,40,501,60),所述装置基本上包括: 第一不透水膜(12,42,52,62); 叠置在第一膜(12,42,52,62)上的第二不透水膜(14,44,54,64); 所述第一和第二膜固定地附接在其表面的至少一部分上,限定了周边区域,以便限定形成内部反应腔(16,46,56,66)的间隙空间,没有任何流体连通 与所述分析装置的外部(10,40,501,60); 放置在与所述样品(28)接触的所述内部反应腔(16,46,56,66)内的至少一个分析装置(18,47,57,67); 至少一种设计用于创建样品进入所述内部反应腔的方式的装置。 本发明还涉及包括这种分析装置的容器(22,50,70)。 本发明还涉及一种分析包含在容器中的样品的方法,其中使用了根据本发明的分析装置。
    • 9. 发明授权
    • Method for using a test card
    • 使用测试卡的方法
    • US07259021B2
    • 2007-08-21
    • US10220845
    • 2001-03-06
    • Bruno Colin
    • Bruno Colin
    • G01N1/10
    • B01L3/502723B01L3/5025B01L3/502738B01L2200/0673B01L2300/0816B01L2400/0481B01L2400/0655G01N2035/00148Y10T436/2575
    • The present invention relates to a method for using a test card (1) comprising at least one fluid circuit, constituting a network of channels (3) and/or of compartments (17), for transferring at least one biological liquid from at least one inlet (2) to at least one outlet (6, 17), and a hydrophobic fluid is injected into the test card, into all or part of the network of said card, prior to the transfer of the biological liquid(s), said hydrophobic fluid filling the capillary spaces formed by the angles of the network of channels and/or of compartments of the card and avoiding the formation of bubbles and/or of dead volumes during the transfer of the biological liquid.The invention is of preferential use in the field of microfluidics applied to biology.
    • 本发明涉及一种使用测试卡(1)的方法,该测试卡(1)包括构成通道(3)和/或隔间(17)的网络的至少一个流体回路,用于从至少一个 入口(2)到至少一个出口(6,17),并且疏水性流体在生物液体转移之前被注入到测试卡中,进入所述卡的全部或部分网络中,所述生物液体 疏水性流体填充由通道网络和/或隔室的角度形成的毛细管空间,并避免在生物液体的转移期间形成气泡和/或死体积。 本发明在应用于生物学的微流体领域中被优先使用。