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1. 发明授权

US08423146B2 Electrical stimulation to alleviate chronic pelvic pain 有权
标题翻译：电刺激缓解慢性盆腔疼痛
公开(公告)号：US08423146B2
公开(公告)日：2013-04-16
申请号：US12861165
申请日：2010-08-23
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/34
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/0556 , A61N1/36007
摘要： The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.
摘要翻译：本公开描述了一种将电刺激施加到患者的基因原经神经的生殖器神经或生殖器分支的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，诸如袖带电极，电极引线和微刺激器，其植入在靠近单个或两个基因视网膜神经和患者的单个或两个基因颅神经的生殖分支的不同位置处。当植入到生殖器神经分支附近时，电极可以在生殖神经分支附近植入。在男性患者中，刺激可以靠近精子束递送，精索包含生殖器神经分支的一部分。

2. 发明授权

US08417346B2 Electrical stimulation of iliohypogastric nerve to alleviate chronic pelvic pain 有权
标题翻译：电刺激髂腹下神经缓解慢性盆腔疼痛
公开(公告)号：US08417346B2
公开(公告)日：2013-04-09
申请号：US12815084
申请日：2010-06-14
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/36
CPC分类号： A61K31/485 , A61K31/7076 , A61K38/31 , A61M5/14276 , A61M5/172 , A61M2005/1405 , A61M2205/054 , A61M2205/3523 , A61M2205/50 , A61M2210/1021 , A61N1/0551 , A61N1/0556 , A61N1/36007 , A61N1/36071 , A61N1/37288
摘要： The disclosure describes a method and system for applying electrical stimulation to an iliohypogastric nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both iliohypogastric nerves of a patient. In particular, the electrode may be implanted proximate or adjacent to an anterior cutaneous branch of one or both iliohypogastric nerves, a lateral cutaneous branch of one or both iliohypogastric nerves, or one or both of iliohypogastric nerves above the branch point.
摘要翻译：本公开描述了一种对患者的髂腹下神经施加电刺激的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，例如袖带电极，电极引线和微刺激器，其植入在靠近患者的单个或两个髂腹下神经的各个位置处。特别地，电极可以被植入邻近或邻近髂腹下神经的一个或两个的前皮肤分支，一个或两个髂腹下神经的外侧皮肤分支，或在分支点之上的髂腹下神经中的一个或两个。

3. 发明授权

US07809443B2 Electrical stimulation to alleviate chronic pelvic pain 有权
标题翻译：电刺激缓解慢性盆腔疼痛
公开(公告)号：US07809443B2
公开(公告)日：2010-10-05
申请号：US11413621
申请日：2006-04-28
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/34
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/0556 , A61N1/36007
摘要： The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.
摘要翻译：本公开描述了一种将电刺激施加到患者的基因原经神经的生殖器神经或生殖器分支的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，诸如袖带电极，电极引线和微刺激器，其植入在靠近单个或两个基因视网膜神经和患者的单个或两个基因颅神经的生殖分支的不同位置处。当植入到生殖器神经分支附近时，电极可以在生殖神经分支附近植入。在男性患者中，刺激可以靠近精子束递送，精索包含生殖器神经分支的一部分。

4. 发明申请

US20100249876A1 ELECTRICAL STIMULATION OF ILIOHYPOGASTRIC NERVE TO ALLEVIATE CHRONIC PELVIC PAIN 有权
标题翻译： ILIOHYPOGASTRIC神经电刺激治疗慢性疼痛疼痛
公开(公告)号：US20100249876A1
公开(公告)日：2010-09-30
申请号：US12815084
申请日：2010-06-14
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/34
CPC分类号： A61K31/485 , A61K31/7076 , A61K38/31 , A61M5/14276 , A61M5/172 , A61M2005/1405 , A61M2205/054 , A61M2205/3523 , A61M2205/50 , A61M2210/1021 , A61N1/0551 , A61N1/0556 , A61N1/36007 , A61N1/36071 , A61N1/37288
摘要： The disclosure describes a method and system for applying electrical stimulation to an iliohypogastric nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both iliohypogastric nerves of a patient. In particular, the electrode may be implanted proximate or adjacent to an anterior cutaneous branch of one or both iliohypogastric nerves, a lateral cutaneous branch of one or both iliohypogastric nerves, or one or both of iliohypogastric nerves above the branch point.
摘要翻译：本公开描述了一种对患者的髂腹下神经施加电刺激的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，例如袖带电极，电极引线和微刺激器，其植入在靠近患者的单个或两个髂腹下神经的各个位置处。特别地，电极可以被植入邻近或邻近髂腹下神经的一个或两个的前皮肤分支，一个或两个髂腹下神经的外侧皮肤分支，或在分支点之上的髂腹下神经中的一个或两个。

5. 发明授权

US08219202B2 Electrical stimulation of ilioinguinal nerve to alleviate chronic pelvic pain 有权
标题翻译：电刺激髂骨神经缓解慢性盆腔疼痛
公开(公告)号：US08219202B2
公开(公告)日：2012-07-10
申请号：US11414615
申请日：2006-04-28
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/00
CPC分类号： A61N1/36007 , A61N1/0551 , A61N1/0556 , A61N1/36071 , A61N1/37288
摘要： The disclosure describes a method and system for applying electrical stimulation to an ilioinguinal nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both ilioinguinal nerves of a patient. In particular, the electrode may be implanted proximate or adjacent to a region of the ilioinguinal nerve above or below the inguinal canal.
摘要翻译：本公开描述了一种将电刺激施加到患者的髂神经的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，例如袖带电极，电极引线和微刺激器，其植入在靠近患者的单个或两个髂骨神经的各个位置处。特别地，电极可以在腹股沟管上方或下方的髂骨神经的区域附近或邻近植入。

6. 发明申请

US20100318157A1 ELECTRICAL STIMULATION TO ALLEVIATE CHRONIC PELVIC PAIN 有权
标题翻译：电刺激治疗慢性疼痛疼痛
公开(公告)号：US20100318157A1
公开(公告)日：2010-12-16
申请号：US12861165
申请日：2010-08-23
申请人： Jonathon E. Giftakis , Martin T. Gerber
发明人： Jonathon E. Giftakis , Martin T. Gerber
IPC分类号： A61N1/00
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/0556 , A61N1/36007
摘要： The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.
摘要翻译：本公开描述了一种将电刺激施加到患者的基因原经神经的生殖器神经或生殖器分支的方法和系统。该系统包括电刺激器，其应用电刺激以缓解盆腔疼痛。该系统可以对男性或女性进行电刺激用于骨盆疼痛。电刺激器可以包括各种类型的电极，诸如袖带电极，电极引线和微刺激器，其植入在靠近单个或两个基因视网膜神经和患者的单个或两个基因颅神经的生殖分支的不同位置处。当植入到生殖器神经分支附近时，电极可以在生殖神经分支附近植入。在男性患者中，刺激可以靠近精子束递送，精索包含生殖器神经分支的一部分。

7. 发明授权

US09713706B2 Implantable medical elongated member including intermediate fixation 有权
公开(公告)号：US09713706B2
公开(公告)日：2017-07-25
申请号：US11591448
申请日：2006-10-31
申请人： Martin T. Gerber
发明人： Martin T. Gerber
IPC分类号： A61N1/00 , A61N1/05
CPC分类号： A61N1/0529 , A61N1/0534 , A61N1/0536 , A61N1/0539 , A61N1/0553 , A61N1/0558 , A61N1/057
摘要： An implantable medical elongated member extends between a proximal end configured to be coupled to a medical device and a distal end. The implantable elongated member includes one or more fixation elements coupled to at least a middle portion and/or a proximal portion of the elongated member in order to substantially fix a position of the elongated member to tissue at one or more intermediate points between the proximal end and the distal end of the elongated member.

8. 发明授权

US09272140B2 Method, system and device for treating disorders of the pelvic floor by electrical stimulation of the sacral and/or pudendal nerves 有权
标题翻译：用于通过电刺激骶神经和/或阴部神经来治疗盆底疾病的方法，系统和装置
公开(公告)号：US09272140B2
公开(公告)日：2016-03-01
申请号：US12059243
申请日：2008-03-31
申请人： Martin T. Gerber
发明人： Martin T. Gerber
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36007 , A61N1/0507 , A61N1/0521 , A61N1/0551 , A61N1/36071 , A61N1/36107
摘要： Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of tissue volumes at two or more locations adjacent sacral nerves or portions thereof, and/or pudendal nerves or portions thereof. Two or more electrical stimulation regimes are applied on a continuous, alternating, intermittent or other basis to the respective tissue volumes in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary and/or fecal voiding dysfunctions such as constipation, incontinence disorders such as urge frequency and urinary retention disorders, sexual dysfunctions such as orgasmic and erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.
摘要翻译：描述了通过在邻近骶神经或其部分的两个或更多个位置和/或阴部神经或其部分上的组织体积的电刺激来治疗盆底的各种疾病的可植入装置和方法。两种或更多种电刺激方案以连续，交替，间歇或其他方式以相应的组织体积施用，其数量和方式有效地治疗许多障碍，包括但不限于尿和/或粪便排泄功能障碍例如便秘，失禁症例如呼吸频率和尿潴留障碍，性功能障碍如高血压和勃起功能障碍，盆腔疼痛，前列腺炎，前列腺痛和前列腺痛。

9. 发明授权

US09144640B2 Sorbent cartridge configurations for improved dialysate regeneration 有权
标题翻译：吸附剂盒配置，用于改善透析液再生
公开(公告)号：US09144640B2
公开(公告)日：2015-09-29
申请号：US13836973
申请日：2013-03-15
申请人： Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
发明人： Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
IPC分类号： A61M1/16
CPC分类号： A61M1/1656 , A61M1/1654 , A61M1/1668 , A61M1/167 , A61M1/1696 , A61M1/287 , A61M1/3486 , A61M2205/02 , B01D15/08
摘要： A regeneration system that has a first regeneration module containing a first chosen regenerative substance; a second regeneration module containing the first chosen regenerative substance; and a first mixing chamber. A first outlet stream of a fluid sequentially exits the first mixing chamber, flows through the first regeneration module in fluid communication with the first chosen regenerative substance and returns to the first mixing chamber, and a second outlet stream of the fluid sequentially exits the first mixing chamber and flows through the second regeneration module in fluid communication with the first chosen regenerative substance.
摘要翻译：一种再生系统，其具有包含第一选择再生物质的第一再生模块; 包含第一选择再生物质的第二再生模块; 和第一混合室。流体的第一出口流顺序地离开第一混合室，流过第一再生模块与第一选择的再生物质流体连通并返回到第一混合室，并且流体的第二出口流依次离开第一混合并且与第一选择的再生物质流体连通地流过第二再生模块。

10. 发明申请

US20140217028A1 SORBENT CARTRIDGE CONFIGURATIONS FOR IMPROVED DIALYSATE REGENERATION 有权
标题翻译：用于改进的透析再生的SORBENT CARTRIDGE配置
公开(公告)号：US20140217028A1
公开(公告)日：2014-08-07
申请号：US13836973
申请日：2013-03-15
申请人： Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
发明人： Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
IPC分类号： A61M1/16
CPC分类号： A61M1/1656 , A61M1/1654 , A61M1/1668 , A61M1/167 , A61M1/1696 , A61M1/287 , A61M1/3486 , A61M2205/02 , B01D15/08
摘要： A regeneration system that has a first regeneration module containing a first chosen regenerative substance; a second regeneration module containing the first chosen regenerative substance; and a first mixing chamber. A first outlet stream of a fluid sequentially exits the first mixing chamber, flows through the first regeneration module in fluid communication with the first chosen regenerative substance and returns to the first mixing chamber, and a second outlet stream of the fluid sequentially exits the first mixing chamber and flows through the second regeneration module in fluid communication with the first chosen regenerative substance.
摘要翻译：一种再生系统，其具有包含第一选择再生物质的第一再生模块; 包含第一选择再生物质的第二再生模块; 和第一混合室。流体的第一出口流顺序地离开第一混合室，流过第一再生模块与第一选择的再生物质流体连通并返回到第一混合室，并且流体的第二出口流依次离开第一混合并且与第一选择的再生物质流体连通地流过第二再生模块。

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