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1. 发明授权

US08457759B2 Systems and methods for adjusting electrical therapy based on impedance changes 有权
公开(公告)号：US08457759B2
公开(公告)日：2013-06-04
申请号：US13620519
申请日：2012-09-14
申请人： Jon Parker , Andre B. Walker , Udai Singh
发明人： Jon Parker , Andre B. Walker , Udai Singh
IPC分类号： A61N1/00
CPC分类号： A61N1/36139 , A61N1/0551 , A61N1/08 , A61N1/3605 , A61N1/36071 , A61N1/36142 , A61N2001/083
摘要： System and methods for adjusting electrical therapy based on impedance changes are disclosed herein. A method in accordance with a particular embodiment includes applying a therapeutic electrical signal to a patient via an implanted portion of a patient stimulation system that includes a signal delivery device in electrical communication with a target neural population of the patient. The electrical signal is delivered in accordance with a signal delivery parameter having a first value. Using the implanted portion of the patient stimulation system, a change in an impedance of an electrical circuit that includes the signal delivery device is detected. Based at least in part on the detected impedance change, the method can further include automatically adjusting the value of the signal delivery parameter from the first value to a second value different from the first, without human intervention.

2. 发明授权

US08311639B2 Systems and methods for adjusting electrical therapy based on impedance changes 有权
标题翻译：基于阻抗变化调整电疗法的系统和方法
公开(公告)号：US08311639B2
公开(公告)日：2012-11-13
申请号：US12499769
申请日：2009-07-08
申请人： Jon Parker , Andre B. Walker , Udai Singh
发明人： Jon Parker , Andre B. Walker , Udai Singh
IPC分类号： A61N1/00
CPC分类号： A61N1/36139 , A61N1/0551 , A61N1/08 , A61N1/3605 , A61N1/36071 , A61N1/36142 , A61N2001/083
摘要： System and methods for adjusting electrical therapy based on impedance changes are disclosed herein. A method in accordance with a particular embodiment includes applying a therapeutic electrical signal to a patient via an implanted portion of a patient stimulation system that includes a signal delivery device in electrical communication with a target neural population of the patient. The electrical signal is delivered in accordance with a signal delivery parameter having a first value. Using the implanted portion of the patient stimulation system, a change in an impedance of an electrical circuit that includes the signal delivery device is detected. Based at least in part on the detected impedance change, the method can further include automatically adjusting the value of the signal delivery parameter from the first value to a second value different from the first, without human intervention.
摘要翻译：本文公开了用于调整基于阻抗变化的电疗法的系统和方法。根据特定实施例的方法包括经由患者刺激系统的植入部分向患者施加治疗电信号，患者刺激系统包括与患者的目标神经群体电连通的信号传递装置。电信号根据具有第一值的信号传递参数传送。使用患者刺激系统的植入部分，检测包括信号传递装置的电路的阻抗的变化。至少部分地基于检测到的阻抗变化，所述方法还可以包括在没有人为干预的情况下，将信号传递参数的值从第一值自动调整到与第一值不同的第二值。

3. 发明申请

US20110009927A1 SYSTEMS AND METHODS FOR ADJUSTING ELECTRICAL THERAPY BASED ON IMPEDANCE CHANGES 有权
标题翻译：基于阻抗变化调整电疗的系统和方法
公开(公告)号：US20110009927A1
公开(公告)日：2011-01-13
申请号：US12499769
申请日：2009-07-08
申请人： Jon Parker , Andre B. Walker , Udai Singh
发明人： Jon Parker , Andre B. Walker , Udai Singh
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/0551 , A61N1/08 , A61N1/3605 , A61N1/36071 , A61N1/36142 , A61N2001/083
摘要： System and methods for adjusting electrical therapy based on impedance changes are disclosed herein. A method in accordance with a particular embodiment includes applying a therapeutic electrical signal to a patient via an implanted portion of a patient stimulation system that includes a signal delivery device in electrical communication with a target neural population of the patient. The electrical signal is delivered in accordance with a signal delivery parameter having a first value. Using the implanted portion of the patient stimulation system, a change in an impedance of an electrical circuit that includes the signal delivery device is detected. Based at least in part on the detected impedance change, the method can further include automatically adjusting the value of the signal delivery parameter from the first value to a second value different from the first, without human intervention.
摘要翻译：本文公开了用于调整基于阻抗变化的电疗法的系统和方法。根据特定实施例的方法包括经由患者刺激系统的植入部分向患者施加治疗电信号，患者刺激系统包括与患者的目标神经群体电连通的信号传递装置。电信号根据具有第一值的信号传递参数传送。使用患者刺激系统的植入部分，检测包括信号传递装置的电路的阻抗的变化。至少部分地基于检测到的阻抗变化，所述方法还可以包括在没有人为干预的情况下，将信号传递参数的值从第一值自动调整到与第一值不同的第二值。

4. 发明授权

US08060218B2 Inductive element for intravascular implantable devices 失效
标题翻译：用于血管内植入装置的感应元件
公开(公告)号：US08060218B2
公开(公告)日：2011-11-15
申请号：US11833101
申请日：2007-08-02
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/05
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译：适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。电感元件包括具有对应于外形的外表面轮廓的芯。一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。绕组也位于相对于细长形状因子沿径向引导磁场。在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。

5. 发明授权

US08961390B2 Sensorless flow estimation for implanted ventricle assist device 有权
标题翻译：用于植入式脑室辅助装置的无传感器流量估计
公开(公告)号：US08961390B2
公开(公告)日：2015-02-24
申请号：US13939964
申请日：2013-07-11
申请人： Jeffrey LaRose , Udai Singh
发明人： Jeffrey LaRose , Udai Singh
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , A61M2205/3379
摘要： A method of estimating the blood flow rate of a heart ventricle assist device which is positioned externally of, or implanted in, a patient. The assist device comprises a blood pump having a rapidly rotating, electrically powered impeller, and comprises briefly interrupting power to the impeller to cause its rotation to slow. From this, blood viscosity can be estimated, which viscosity is used to obtain real time, estimated blood flow rates and pressure heads. Apparatus for accomplishing this is disclosed.
摘要翻译：一种估计位于患者外部或植入患者的心室辅助装置的血液流速的方法。辅助装置包括具有快速旋转的电动叶轮的血泵，并且包括短暂地切断叶轮的动力以使其旋转减速。由此，可以估计血液粘度，使用哪种粘度来获得实时，估计的血液流速和压力头。公开了实现这一点的装置。

6. 发明申请

US20130296634A1 SENSORLESS FLOW ESTIMATION FOR IMPLANTED VENTRICLE ASSIST DEVICE 有权
标题翻译：用于植入式通气辅助装置的无传感流量估计
公开(公告)号：US20130296634A1
公开(公告)日：2013-11-07
申请号：US13939964
申请日：2013-07-11
申请人： Jeffrey LaRose , Udai Singh
发明人： Jeffrey LaRose , Udai Singh
IPC分类号： A61M1/10
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , A61M2205/3379
摘要： A method of estimating the blood flow rate of a heart ventricle assist device which is positioned externally of, or implanted in, a patient. The assist device comprises a blood pump having a rapidly rotating, electrically powered impeller, and comprises briefly interrupting power to the impeller to cause its rotation to slow. From this, blood viscosity can be estimated, which viscosity is used to obtain real time, estimated blood flow rates and pressure heads. Apparatus for accomplishing this is disclosed.
摘要翻译：一种估计位于患者外部或植入患者的心室辅助装置的血液流速的方法。辅助装置包括具有快速旋转的电动叶轮的血泵，并且包括短暂地切断叶轮的动力以使其旋转减速。由此，可以估计血液粘度，使用哪种粘度来获得实时，估计的血液流速和压力头。公开了实现这一点的装置。

7. 发明授权

US08335571B2 Inductive element for intravascular implantable devices 失效
标题翻译：用于血管内植入装置的感应元件
公开(公告)号：US08335571B2
公开(公告)日：2012-12-18
申请号：US13295916
申请日：2011-11-14
申请人： Udai Singh , Stephen C. Masson
发明人： Udai Singh , Stephen C. Masson
IPC分类号： A61N1/05
CPC分类号： A61N1/3758 , A61N1/3782 , A61N1/3956 , H01F17/043 , H01F27/26
摘要： An inductive element adapted for use in implantable intravascular devices (IIDs) having an elongate form factor with a cross-section. The inductive element includes a core that has an outer surface contour that corresponds to the form factor. A set of elongate, or oblong, windings are situated lengthwise along the major length dimension of the inductive element. The windings are also situated to direct a magnetic field along a radial direction in relation to the elongate form factor. In one embodiment the form factor is generally cylindrical and the cross-section is generally round.
摘要翻译：适用于可植入的血管内装置（IID）的电感元件，其具有具有横截面的细长形状因子。电感元件包括具有对应于外形的外表面轮廓的芯。一组细长或长圆形的绕组沿电感元件的主长度尺寸纵向设置。绕组也位于相对于细长形状因子沿径向引导磁场。在一个实施例中，形状因子通常是圆柱形的，并且横截面通常是圆形的。

8. 发明申请

US20110137108A1 SENSORLESS FLOW ESTIMATION FOR IMPLANTED VENTRICLE ASSIST DEVICE 有权
标题翻译：用于植入式通气辅助装置的无传感流量估计
公开(公告)号：US20110137108A1
公开(公告)日：2011-06-09
申请号：US13027811
申请日：2011-02-15
申请人： Jeffrey A. LaRose , Udai Singh
发明人： Jeffrey A. LaRose , Udai Singh
IPC分类号： A61M1/12
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , A61M2205/3379
摘要： A method of estimating the blood flow rate of a heart ventricle assist device which is positioned externally of, or implanted in, a patient. The assist device comprises a blood pump having a rapidly rotating, electrically powered impeller, and comprises briefly interrupting power to the impeller to cause its rotation to slow. From this, blood viscosity can be estimated, which viscosity is used to obtain real time, estimated blood flow rates and pressure heads. Apparatus for accomplishing this is disclosed.
摘要翻译：一种估计位于患者外部或植入患者的心室辅助装置的血液流速的方法。辅助装置包括具有快速旋转的电动叶轮的血泵，并且包括短暂地切断叶轮的动力以使其旋转减速。由此，可以估计血液粘度，使用哪种粘度来获得实时，估计的血液流速和压力头。公开了实现这一点的装置。

9. 发明申请

US20070232934A1 Sensorless Flow Estimation for Implanted Ventricle Assist Device 有权
标题翻译：植入式心室辅助装置的无传感器流量估计
公开(公告)号：US20070232934A1
公开(公告)日：2007-10-04
申请号：US11597230
申请日：2005-05-24
申请人： Jeffrey LaRose , Udai Singh
发明人： Jeffrey LaRose , Udai Singh
IPC分类号： A61B5/02
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , A61M2205/3379
摘要： A method of estimating the blood flow rate of a heart ventricle assist device which is positioned externally of, or implanted in, a patient. The assist device comprises a blood pump having a rapidly rotating, electrically powered impeller, and comprises briefly interrupting power to the impeller to cause its rotation to slow. From this, blood viscosity can be estimated, which viscosity is used to obtain real time, estimated blood flow rates and pressure heads. Apparatus for accomplishing this is disclosed.
摘要翻译：一种估计位于患者外部或植入患者的心室辅助装置的血液流速的方法。辅助装置包括具有快速旋转的电动叶轮的血泵，并且包括短暂地切断叶轮的动力以使其旋转减速。由此，可以估计血液粘度，使用哪种粘度来获得实时，估计的血液流速和压力头。公开了实现这一点的装置。

10. 发明授权

US08506470B2 Sensorless flow estimation for implanted ventricle assist device 有权
公开(公告)号：US08506470B2
公开(公告)日：2013-08-13
申请号：US13027811
申请日：2011-02-15
申请人： Jeffrey A. LaRose , Udai Singh
发明人： Jeffrey A. LaRose , Udai Singh
IPC分类号： A61M1/12
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , A61M2205/3379
摘要： A method of estimating the blood flow rate of a heart ventricle assist device which is positioned externally of, or implanted in, a patient. The assist device comprises a blood pump having a rapidly rotating, electrically powered impeller, and comprises briefly interrupting power to the impeller to cause its rotation to slow. From this, blood viscosity can be estimated, which viscosity is used to obtain real time, estimated blood flow rates and pressure heads. Apparatus for accomplishing this is disclosed.

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