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1. 发明申请

US20060251581A1 Method for treatment of uterine fibroid tumors 审中-公开
标题翻译：治疗子宫肌瘤的方法
公开(公告)号：US20060251581A1
公开(公告)日：2006-11-09
申请号：US11124828
申请日：2005-05-09
申请人： Jon McIntyre , Arthur Madenjian
发明人： Jon McIntyre , Arthur Madenjian
IPC分类号： A61K49/00 , A61K49/04 , A61K9/14
CPC分类号： A61K9/0034 , A61K9/0024 , A61K9/0092 , A61K9/06 , A61K31/045 , A61K31/717 , A61K31/734 , A61K31/74 , A61K31/79 , A61K33/14 , A61K45/06 , A61K49/0002 , A61K2300/00
摘要： Various injectable or insertable uterine fibroid treatment formulations are provided, which comprise a uterine fibroid treatment agent in an amount effective to cause shrinkage or elimination of uterine fibroids. The injectable or insertable formulations are typically solids, semi-solids or high-viscosity fluids. Other aspects of the invention are directed to systems and methods for treatment of uterine fibroids.
摘要翻译：提供各种可注射或可插入的子宫肌瘤治疗制剂，其包括有效引起子宫肌瘤收缩或消除的量的子宫肌瘤治疗剂。可注射或可插入的制剂通常为固体，半固体或高粘度流体。本发明的其它方面涉及用于治疗子宫肌瘤的系统和方法。

2. 发明申请

US20060178698A1 Method and device for canulation and occlusion of uterine arteries 审中-公开
标题翻译：子宫动脉阻塞和闭塞的方法和装置
公开(公告)号：US20060178698A1
公开(公告)日：2006-08-10
申请号：US11053343
申请日：2005-02-08
申请人： Jon McIntyre , Michael Madden
发明人： Jon McIntyre , Michael Madden
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/02 , A61B17/12131 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/3415 , A61B17/42 , A61B2017/1205 , A61B2017/12054 , A61M39/06
摘要： A method for treating a uterine fibroid comprises forming an incision in a vaginal fornix to expose a first blood vessel supplying the fibroid, forming an opening in the first blood vessel and inserting an introducer into the first blood vessel via the opening in combination with the steps of advancing a catheter to a desired position within the first blood vessel via the introducer and introducing an occlusive agent into the first blood vessel through the catheter to block blood flow through the first blood vessel. A device for treating uterine fibroids comprises an elongated sheath sized for insertion into uterine arteries via an incision in the vaginal fornix, the sheath including a sheath lumen extending from a first sheath opening formed in a proximal end of the sheath to a second sheath opening formed in a distal end of the sheath and a body a distal end of which is connected to the proximal end of the sheath, the body including a body lumen extending therethrough from a first body opening at a proximal end of the body and a second body opening at the distal end thereof, the second body lumen communicating with the sheath lumen in combination with a hemostatic valve controlling the flow of blood through the body lumen.
摘要翻译：一种治疗子宫肌瘤的方法包括在阴道穹窿中形成切口以暴露供应纤维瘤的第一血管，在第一血管中形成开口，并通过开口将引入器插入第一血管中，并与步骤通过导引器将导管推进到第一血管内的期望位置，并通过导管将闭塞剂引入第一血管，以阻断通过第一血管的血液。用于治疗子宫肌瘤的装置包括细长的护套，其尺寸适于通过阴道穹窿中的切口插入子宫动脉中，所述护套包括从形成在护套的近端中的第一护套开口延伸到形成的第二护套开口的护套腔在所述护套的远端中，并且其远端连接到所述护套的近端的主体，所述主体包括从所述主体的近端处的第一主体开口延伸穿过的主体内腔和第二主体开口在其远端处，与控制通过体腔的血流的止血阀组合地与鞘腔连通的第二体腔。

3. 发明申请

US20050107781A1 System and method for tissue ablation 失效
标题翻译：组织消融的系统和方法
公开(公告)号：US20050107781A1
公开(公告)日：2005-05-19
申请号：US10993306
申请日：2004-11-18
申请人： Isaac Ostrovsky , Jon McIntyre
发明人： Isaac Ostrovsky , Jon McIntyre
IPC分类号： A61B18/14
CPC分类号： A61B18/1482 , A61B18/14 , A61B18/1442 , A61B18/1815 , A61B2018/00273 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1467 , A61B2018/1475
摘要： A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.
摘要翻译：组织消融装置包括具有相反极性的第一和第二电极，第一电极被安装到第一细长构件，以相对于第二电极移动，以便将其与之隔离一段期望的距离。消融组织的方法包括将第一和第二电极相对于要消融的组织块插入所需的初始位置，并将电能施加到第一和第二电极，以将第一和第二电极之间的组织的第一部分与将电能施加到从期望的初始位置分离所需的第二位置的距离，所述距离被选择为通过待消融的组织的第二部分转移围绕组织的第一部分的电能，围绕第一部分的组织的第二部分组织。

4. 发明申请

US20070066990A1 Device for forming a fluid tight seal during a procedure within a hollow organ 审中-公开
标题翻译：用于在中空器官内的过程中形成流体密封的装置
公开(公告)号：US20070066990A1
公开(公告)日：2007-03-22
申请号：US11230147
申请日：2005-09-19
申请人： Andrew Marsella , Aidan Petrie , Todd Sloan , Jon McIntyre , David Robson , Joseph Gordon , Jeff Cheek , John Howard
发明人： Andrew Marsella , Aidan Petrie , Todd Sloan , Jon McIntyre , David Robson , Joseph Gordon , Jeff Cheek , John Howard
IPC分类号： A61M29/00
CPC分类号： A61M29/02 , A61B17/4241 , A61B18/04 , A61B18/12 , A61B2017/00898 , A61B2017/3419 , A61B2017/4225 , A61B2018/046 , A61M2025/1052
摘要： A device for accessing a hollow organ comprises an elongated body sized for insertion into an opening into a hollow organ, the elongated body including a working channel extending therethrough from a proximal opening which, when the seal is in an operative position, is located proximally of the opening to a distal opening which, when the seal is in the operative position, opens into the hollow organ and a seal extending around a portion of the elongated body between the proximal and distal openings, the seal expanding from an insertion configuration to a sealing configuration.
摘要翻译：一种用于进入中空器官的装置，包括尺寸适于插入到中空器官的开口中的细长体，所述细长体包括从近端开口延伸穿过其的工作通道，所述近侧开口在所述密封件处于操作位置时位于远端开口的开口，当密封件处于操作位置时，该远端开口通向中空器官，以及在近端和远端开口之间围绕细长体的一部分延伸的密封件，密封件从插入构型向密封件组态。

5. 发明申请

US20060264912A1 Medical devices for treating urological and uterine conditions 有权
标题翻译：用于治疗泌尿和子宫疾病的医疗器械
公开(公告)号：US20060264912A1
公开(公告)日：2006-11-23
申请号：US11125296
申请日：2005-05-09
申请人： Jon McIntyre , Kenneth Daignault
发明人： Jon McIntyre , Kenneth Daignault
IPC分类号： A61K9/22
CPC分类号： A61M27/008 , A61K9/0034 , A61K9/0036 , A61K9/0039 , A61L31/16 , A61L2300/602 , A61M2025/0056 , A61M2210/1078 , A61M2210/1433 , A61M2210/1475
摘要： The present invention relates to implantable or insertable medical devices that treat uterine and urological conditions that cause chronic pelvic pain and other symptoms. In another aspect, the present invention relates to methods of manufacturing such implantable or insertable medical devices.
摘要翻译：本发明涉及可治疗或可插入的医疗装置，其治疗引起慢性盆腔疼痛和其他症状的子宫和泌尿系统状况。在另一方面，本发明涉及制造这种可植入或可插入的医疗装置的方法。

6. 发明申请

US20060178665A1 Radio frequency ablation system with integrated ultrasound imaging 有权
公开(公告)号：US20060178665A1
公开(公告)日：2006-08-10
申请号：US11053344
申请日：2005-02-08
申请人： Todd Sloan , Isaac Ostrovsky , Jon McIntyre
发明人： Todd Sloan , Isaac Ostrovsky , Jon McIntyre
IPC分类号： A61B18/14 , A61B8/12
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432 , A61B2090/378 , A61B2090/3782
摘要： A tissue ablation system comprises a first electrode assembly adapted for insertion into a target tissue mass within a body, the first electrode assembly including a first electrode coupled to a source of RF energy in combination with an ultrasound imaging probe movably coupled to the first electrode assembly for insertion with the first electrode assembly to a desired location relative to the target tissue mass, the probe being movable relative to the first electrode assembly between an insertion configuration in which a distal end of the probe covers a distal end of the first electrode assembly and a deployed configuration in which the distal end of the first electrode assembly is uncovered. A method of ablating target tissue within a body comprises placing a distal dome of an ultrasound imaging probe in overlying alignment with a first cannula of an RF ablation device and inserting the probe and the RF ablation device through a lumen of an insertion device to a desired location adjacent to a target tissue mass in combination with moving the distal dome away from a distal end of the first cannula to expose a distal end thereof, inserting the distal end of the first cannula into the target tissue mass to position a first electrode of the RF ablation device at a first desired location within the target tissue mass, obtaining an image of the target tissue mass and the first electrode via the probe and applying RF energy to the target tissue mass via the first electrode.

7. 发明申请

US20070232871A1 Method and system for determining tissue properties 审中-公开
标题翻译：用于确定组织性质的方法和系统
公开(公告)号：US20070232871A1
公开(公告)日：2007-10-04
申请号：US11397123
申请日：2006-04-03
申请人： Edward Sinofsky , Jon McIntyre
发明人： Edward Sinofsky , Jon McIntyre
IPC分类号： A61B18/18 , A61B18/04 , A61B5/00
CPC分类号： A61B5/0084 , A61B5/0075 , A61B18/02 , A61B18/14 , A61B18/20 , A61B2017/00057 , A61N7/02 , A61N2007/0078
摘要： A probe for detecting changes in tissue properties comprising an illumination element providing light to a target area and a sensing element receiving light from the illumination element after reflection from a target portion of tissue in combination with a device that detects changes in a property of the light received by the sensing element and determining, based on the detected changes in the property of the received light, a change in the target tissue.
摘要翻译：用于检测组织性质的变化的探针，其包括向目标区域提供光的照明元件和从组织的目标部分反射之后接收来自所述照明元件的光的感测元件以及检测所述光的特性变化的装置由感测元件接收并且基于检测到的接收到的光的特性的变化来确定目标组织的变化。

8. 发明申请

US20070038263A1 Percutaneous access for neuromodulation procedures 失效
标题翻译：经皮进入神经调节程序
公开(公告)号：US20070038263A1
公开(公告)日：2007-02-15
申请号：US11178540
申请日：2005-07-11
申请人： Jon McIntyre
发明人： Jon McIntyre
IPC分类号： A61N1/32 , A61N1/34
CPC分类号： H01R13/453 , A61N1/0551 , A61N1/36007 , A61N1/36017 , A61N1/3752 , H01R13/5224 , H01R2201/12
摘要： A neuromodulation system, comprises an implantable electrode which is implanted within a body adjacent to a target nerve structure to which electric energy is to be applied via the electrode and a connection port which is implanted in the body with a proximal surface thereof substantially flush with an outer surface of a skin of the body, the connection port including a device interface for electrically connecting to an external device which remains external to the body in combination with an electric line extending from the device interface to the electrode for carrying electric energy from the external device to the electrode and a cover selectively closing an opening of the external surface of the implanted connection port.
摘要翻译：一种神经调节系统，包括植入电极，所述可植入电极植入在邻近待通过所述电极施加电能的目标神经结构的体内，以及植入所述主体的连接端口，所述连接端口的近端表面基本上与所述连接端口包括用于电连接到外部设备的设备接口，所述外部设备保持在所述主体外部，并与从所述设备接口延伸到所述电极的电线结合，以从外部传送电能装置到电极和盖子，其选择性地封闭植入的连接端口的外表面的开口。

9. 发明申请

US20070021745A1 Bipolar radio frequency ablation device with retractable insulator 有权
标题翻译：具有可伸缩绝缘子的双极射频消融装置
公开(公告)号：US20070021745A1
公开(公告)日：2007-01-25
申请号：US11187669
申请日：2005-07-22
申请人： Jon McIntyre , Isaac Ostrovsky
发明人： Jon McIntyre , Isaac Ostrovsky
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00083 , A61B2018/00196 , A61B2018/00273 , A61B2018/00577 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1467
摘要： An ablation device, comprises a first tubular element and a first electrode which, when in an insertion configuration, is received within the first tubular element, the first electrode being deployable from the first tubular element to anchor in a target portion of tissue at a first electrode operative position in combination with a second electrode which, when in the insertion configuration, is received within the first tubular element, the second electrode being deployable from the first tubular element to anchor in the target portion of tissue at a second electrode operative position separated from the first electrode operative position, the second electrode being deployable independently of the first electrode and an insulating element movable relative to the first electrode to insulate selected portions of the first electrode. A method of ablating tissue, comprises anchoring a first electrode at a first location in a target portion of tissue, deploying a second electrode at a second location in the target portion of tissue and applying current between the first and second electrodes to ablate a first ablation portion of tissue between the first and second electrodes in combination with moving an insulative cover relative to the first electrode to move a conductive portion of the first electrode to a third location within the target tissue, the third location being further from the second location than the first location, moving the second electrode to a fourth location within the target tissue, the fourth location being further from the first location than the second location and applying current between the conductive portion of the first electrode and the second electrode to ablate a second ablation portion of tissue surrounding the first ablation portion of tissue.
摘要翻译：消融装置包括第一管状元件和第一电极，当处于插入构型时，第一电极被容纳在第一管状元件内，第一电极可从第一管状元件展开，以在第一管状元件的第一电极操作位置与第二电极组合，当第二电极处于插入构型时，其被接收在第一管状元件内，第二电极可从第一管状元件展开，以在分开的第二电极操作位置锚定在组织的目标部分中从第一电极操作位置，第二电极可独立于第一电极展开，绝缘元件可相对于第一电极移动，以使第一电极的选定部分绝缘。一种消融组织的方法，包括将第一电极锚定在组织的目标部分中的第一位置处，在组织的目标部分中的第二位置处展开第二电极，并在第一和第二电极之间施加电流以消融第一消融组合在第一和第二电极之间的部分结合使绝缘盖相对于第一电极移动，以将第一电极的导电部分移动到目标组织内的第三位置，第三位置比第二位置更远第一位置，将第二电极移动到目标组织内的第四位置，第四位置比第二位置更远离第一位置，并且在第一电极的导电部分和第二电极之间施加电流以烧蚀第二消融部分围绕组织的第一消融部分的组织。

10. 发明申请

US20060224090A1 Apparatus and method for stiffening tissue 审中-公开
标题翻译：用于加强组织的装置和方法
公开(公告)号：US20060224090A1
公开(公告)日：2006-10-05
申请号：US11092463
申请日：2005-03-29
申请人： Isaac Ostrovsky , Michael Madden , Jon McIntyre , Jozef Slanda
发明人： Isaac Ostrovsky , Michael Madden , Jon McIntyre , Jozef Slanda
IPC分类号： A61H1/00
CPC分类号： A61N7/022 , A61N2007/0078
摘要： An apparatus for stiffening tissue comprises an ultrasound element including an array of ultrasound crystals arranged on a surface, the surface shaped so that energy generated by the crystals converges on a predetermined focusing area. A method of treating tissue comprises positioning adjacent a target portion of tissue to be treated a probe including an ultrasound element, a geometry of the ultrasound element focusing ultrasound energy generated thereby on a predetermined focus area, adjusting the position of the probe so that the predetermined focus area is located at the target portion of tissue and energizing the ultrasound element to treat the target portion of tissue.
摘要翻译：用于加强组织的装置包括超声元件，其包括布置在表面上的超声晶体阵列，所述超声波元件被成形为使得由晶体产生的能量收敛在预定聚焦区域上。一种治疗组织的方法包括定位邻近要处理的组织的目标部分，包括超声元件的探针，超声波元件的几何形状，将由此产生的超声能量聚焦在预定的聚焦区域上，调节探针的位置，使得预定聚焦区域位于组织的目标部分并激励超声波元件以处理组织的目标部分。

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