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1. 发明授权

US5965434A Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds 失效
标题翻译：两亲PH敏感化合物和用于递送生物活性化合物的递送系统
公开(公告)号：US5965434A
公开(公告)日：1999-10-12
申请号：US365841
申请日：1994-12-29
申请人： Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
发明人： Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
IPC分类号： A61K9/127 , C07C219/06 , C07C239/12 , C07C279/12 , C07D295/092 , C07D295/13 , C12N15/88 , C12N15/63
CPC分类号： C07D295/088 , A61K9/1272 , C07C219/06 , C07C239/12 , C07C279/12 , C07D295/13 , C12N15/88 , Y10T428/2984
摘要： The present invention provides amphipathic lipid compounds comprising a hydrophilic, catonic, pH-sensitive moiety, the positive charge of which moiety increases as pH decreases over the pH range of 8.0 to 4.5. Vesicular delivery systems comprising such amphipathic compounds and the use of those systems for delivering biologically active substances to cells are also provided.
摘要翻译：本发明提供包含亲水性，结合性，pH敏感性部分的两亲性脂质化合物，当pH在8.0至4.5的pH范围内pH降低时，其部分的正电荷增加。还提供了包含这种两亲化合物的囊泡递送系统和用于将生物活性物质递送到细胞的那些系统的用途。

2. 发明授权

US5635487A Amphipathic, micellar delivery systems for biologically active polyions 失效
标题翻译：用于生物活性多阴离子的两亲性胶束递送系统
公开(公告)号：US5635487A
公开(公告)日：1997-06-03
申请号：US368150
申请日：1994-12-29
申请人： Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
发明人： Jon A. Wolff , Vladimir Budker , Vladimir Gurevich
IPC分类号： A61K9/107 , A61K9/127 , A61K48/00 , C07J31/00 , C07J41/00 , C07J43/00 , A61K31/415 , A61K31/66
CPC分类号： C07J41/0055 , A61K48/00 , A61K9/1075 , A61K9/1272 , C07J31/003 , C07J41/0066 , C07J43/003
摘要： The present invention provides a composition comprising a population of micelles wherein each micelle comprises at least one amphipathic compound layer that surrounds a non-aqueous core that contains a polyion. Also provided are a method of preparing such a composition and the uses of such compositions for delivering biologically active polyions to cells.
摘要翻译：本发明提供一种包含一组胶束的组合物，其中每个胶束包含至少一个两性化合物层，其包围含有聚阴离子的非水性核心。还提供了制备这种组合物的方法以及这种组合物用于将生物活性聚阴离子递送至细胞的用途。

3. 发明申请

US20130026235A1 LASER SCANNERS HAVING DYNAMIC AIMING-SCANNING MODE 审中-公开
标题翻译：具有动态扫描模式的激光扫描仪
公开(公告)号：US20130026235A1
公开(公告)日：2013-01-31
申请号：US13193752
申请日：2011-07-29
申请人： Vladimir Gurevich , Peter Fazekas , Dariusz J. Madej , Gary G. Schneider , Bruno Vande Vyvre
发明人： Vladimir Gurevich , Peter Fazekas , Dariusz J. Madej , Gary G. Schneider , Bruno Vande Vyvre
IPC分类号： G06K7/14
CPC分类号： G06K7/10633
摘要： A method of operating a laser scanner for reading a barcode. The laser scanner is configured to operate in at least two operating modes including a scanning mode and an aiming mode. The method includes operating the laser scanner in the scanning mode after a trigger signal is generated by a trigger on the laser scanner, and decoding the electrical signal that is received from the photodetector when the laser scanner is in the scanning mode. If the electrical signal from the photodetector is not successfully decoded after a first predetermined time period since the trigger signal is generated, alternating the laser scanner between the aiming mode and the scanning mode.
摘要翻译：一种操作用于读取条形码的激光扫描器的方法。激光扫描器被配置为在包括扫描模式和瞄准模式的至少两种操作模式中操作。该方法包括在激光扫描仪上通过触发产生触发信号之后以扫描模式操作激光扫描仪，以及当激光扫描仪处于扫描模式时解码从光电检测器接收的电信号。如果在产生触发信号之后的第一预定时间段之后来自光电检测器的电信号未成功解码，则在瞄准模式和扫描模式之间交替激光扫描仪。

4. 发明授权

US08006906B2 Arrangement for and method of generating uniform distributed line pattern for imaging reader 有权
标题翻译：为成像读取器生成均匀分布线图的布置和方法
公开(公告)号：US08006906B2
公开(公告)日：2011-08-30
申请号：US12380142
申请日：2009-02-24
申请人： Rong Liu , Vladimir Gurevich
发明人： Rong Liu , Vladimir Gurevich
IPC分类号： G06K7/10
CPC分类号： G06K7/10732
摘要： A module and an arrangement for, as well as a method of, generating a generally uniform distributed line pattern of light on a symbol to be read by image capture, include a light source for generating light along an optical axis in a distribution having different extents along intersecting directions generally perpendicular to the axis, and an optical component for receiving, and for optically modifying, the light from the light source to generate the generally uniform distributed line pattern of light on the symbol. The optical component includes a plurality of compound conic elements spaced apart from one another along one of the directions. Each compound conic element has a pair of conic segments for modifying the light along the one direction. A collimating lens modifies the light along the other of the directions. A solid-state imager has an array of image sensors for capturing return light from the symbol over a field of view having different extents along the intersecting directions.
摘要翻译：在通过图像捕获读取的符号上产生大致均匀的分布线型图案的模块和方法包括：用于沿着具有不同程度的分布中的光轴产生光的光源沿着与轴垂直的相交方向，以及光学部件，用于接收来自光源的光并用于光学修饰以在符号上产生大致均匀的分布的线状图案。光学部件包括沿着其中一个方向彼此间隔开的多个复合圆锥元件。每个复合圆锥元件具有一对锥形段，用于沿一个方向修改光。准直透镜沿着另一个方向修改光。固态成像器具有一组图像传感器，用于在沿着相交方向具有不同程度的视场上从符号捕获返回光。

5. 发明授权

US07762466B2 Two position zoom lens assembly for an imaging-based bar code reader 失效
标题翻译：用于基于成像的条形码读取器的两位置变焦镜头组件
公开(公告)号：US07762466B2
公开(公告)日：2010-07-27
申请号：US12337748
申请日：2008-12-18
申请人： Chinh Tan , Vladimir Gurevich , Rong Liu , Tsi David Shi , Igor Vinogradov , Ming Yu
发明人： Chinh Tan , Vladimir Gurevich , Rong Liu , Tsi David Shi , Igor Vinogradov , Ming Yu
IPC分类号： G06K7/10 , G06K7/00
CPC分类号： G06K7/10702
摘要： An imaging-based bar code reader including: an imaging system for imaging a target bar code within a field of view of the imaging system and projecting light from the field of view onto a sensor array, the imaging system generating image frames of the field of view of the imaging system; the imaging systems including an imaging lens assembly having a plurality of lens and a selection drive mechanism to select between a first optical zoom position defining a first focal length and a first field of view for imaging a target bar code at a close range and a second optical zoom position defining a second focal length and a second field of view for imaging a target bar code at a far range, the second focal length being greater than the first focal length.
摘要翻译：一种基于成像的条形码读取器，包括：成像系统，用于对成像系统的视场内的目标条形码进行成像，并将光从视场投射到传感器阵列上，成像系统产生成像系统的视图; 所述成像系统包括具有多个透镜和选择驱动机构的成像透镜组件，用于在限定第一焦距的第一光学变焦位置和第一视野之间进行选择，以在近距离范围内对目标条形码进行成像，光学变焦位置限定第二焦距和第二视野，用于对远距离的目标条形码进行成像，第二焦距大于第一焦距。

6. 发明申请

US20100078481A1 Imaging reader and method with enhanced aiming pattern detection 有权
标题翻译：具有增强的瞄准图案检测的成像读取器和方法
公开(公告)号：US20100078481A1
公开(公告)日：2010-04-01
申请号：US12286088
申请日：2008-09-26
申请人： Miroslav Trajkovic , Vladimir Gurevich , Heng Zhang
发明人： Miroslav Trajkovic , Vladimir Gurevich , Heng Zhang
IPC分类号： G06K7/10
CPC分类号： G06K7/10722 , G06K7/14 , G06K2207/1011 , G06K2207/1018
摘要： An image capture system for, and a method of, reading an optical code during a reading mode, comprise an aiming assembly including a laser for emitting a laser beam having a variable intensity, and for generating an aiming pattern from the laser beam during an aiming mode prior to the reading mode, and an imager for detecting and capturing an image of the aiming pattern and the code over a field of view by exposure over an exposure time period during the aiming mode, and for detecting and capturing an image of the code over the field of view during the reading mode. A controller is operative for controlling the intensity of the laser beam during the aiming mode by increasing the intensity of the laser beam during the exposure time period to enhance detection and capture of the aiming pattern by the imager, and by decreasing the intensity of the laser beam frame outside the exposure time period for user safety.
摘要翻译：一种用于在读取模式期间读取光学代码的图像捕获系统和一种在读取模式下读取光学代码的方法，包括瞄准组件，其包括用于发射具有可变强度的激光束的激光器，并用于在瞄准期间从激光束产生瞄准图案模式，以及成像器，用于通过在瞄准模式期间的曝光时间段内曝光而在视野上检测和捕获瞄准图案和代码的图像，并且用于检测和捕获代码的图像在阅读模式下的视野。控制器用于在瞄准模式期间通过增加激光束在曝光时间段期间的强度来控制激光束的强度，以增强由成像器对瞄准图案的检测和捕获，并且通过降低激光器的强度光束框架在用户安全的曝光时间段之外。

7. 发明申请

US20100065641A1 SYSTEM FOR INCREASING IMAGING QUALITY 有权
标题翻译：增加成像质量的系统
公开(公告)号：US20100065641A1
公开(公告)日：2010-03-18
申请号：US12211941
申请日：2008-09-17
申请人： Rong Liu , Vladimir Gurevich , Ming Yu
发明人： Rong Liu , Vladimir Gurevich , Ming Yu
IPC分类号： G06K7/10
CPC分类号： G06K7/10831
摘要： A method and apparatus for improving the image quality obtained by an imaging-based scanner comprising a housing supporting one or more protective windows. The apparatus further comprises at least one scanning arrangement, the scanning arrangement comprising illumination and imaging optics. The illumination and imaging optics form a respective field of view for imaging a target object. A light baffle is attached to the scanning arrangement. The light baffle has an aperture corresponding to each of the illumination and imaging optics such that stray light reflected from the protective windows is absorbed by the light baffle, improving the image quality of the imaging-based scanner.
摘要翻译：一种用于改善由基于成像的扫描仪获得的图像质量的方法和装置，其包括支撑一个或多个保护窗的壳体。该装置还包括至少一个扫描装置，扫描装置包括照明和成像光学元件。照明和成像光学器件形成用于对目标物体成像的相应视场。轻型挡板附着在扫描装置上。光挡板具有对应于每个照明和成像光学器件的孔径，使得从保护窗口反射的杂散光被光挡板吸收，从而提高了基于成像的扫描仪的图像质量。

8. 发明申请

US20090108070A1 Enhanced monitoring of laser output power in electro-optical readers 有权
标题翻译：增强电光读取器激光输出功率的监控
公开(公告)号：US20090108070A1
公开(公告)日：2009-04-30
申请号：US11981447
申请日：2007-10-31
申请人： Heng Zhang , Vladimir Gurevich , Ming Yu
发明人： Heng Zhang , Vladimir Gurevich , Ming Yu
IPC分类号： G06K7/10
CPC分类号： G06K7/10584
摘要： Laser power monitoring arrangements interrupt power to a laser used in electro-optical readers upon detection of operating conditions not conforming to preestablished standards. An auxiliary light detector independently monitors the output power of a laser beam, and directly receives a portion of the laser beam reflected from an optical assembly operative for optically modifying the laser beam.
摘要翻译：激光功率监测装置在检测到不符合预先建立的标准的操作条件时，会中断电光读取器中使用的激光的电源。辅助光检测器独立地监视激光束的输出功率，并且直接接收从光学组件反射的激光束的一部分，该光学组件可用于光学修改激光束。

9. 发明申请

US20080170403A1 System and Method for Optimized Visualization on a Display Window 审中-公开
标题翻译：在显示窗口上优化可视化的系统和方法
公开(公告)号：US20080170403A1
公开(公告)日：2008-07-17
申请号：US11742338
申请日：2007-04-30
申请人： Vladimir Gurevich
发明人： Vladimir Gurevich
IPC分类号： F21V9/00 , G02B27/02
CPC分类号： H04M1/0266 , G06F1/1626 , G06F1/1637 , G06F1/1684 , H04M1/21 , H04M1/22 , H04M1/2755 , H04M2250/12
摘要： A system and method optimizes a visualization of a display of a mobile device. The mobile device comprises a housing, a display, and an adaptive device. The display is situated at least partially in an opening of the housing. The adaptive device is disposed at least partially one of within the housing and in the opening. The adaptive device has a property to improve a visibility of the display. The property is related to an ambient lighting condition.
摘要翻译：系统和方法优化移动设备的显示器的可视化。移动设备包括外壳，显示器和自适应设备。显示器至少部分地位于壳体的开口中。自适应装置至少部分地设置在壳体内和开口内。自适应装置具有提高显示器的可视性的性质。该属性与环境照明条件有关。

10. 发明申请

US20080078835A1 Laser power control arrangements in electro-optical readers 有权
标题翻译：电光读取器中的激光功率控制装置
公开(公告)号：US20080078835A1
公开(公告)日：2008-04-03
申请号：US11528909
申请日：2006-09-28
申请人： Vladimir Gurevich , Heng Jade Zhang , David Tsi Shi
发明人： Vladimir Gurevich , Heng Jade Zhang , David Tsi Shi
IPC分类号： G06K7/10
CPC分类号： G06K7/10584
摘要： Laser power control arrangements interrupt power to a laser used in electro-optical readers upon detection of operating conditions not conforming to preestablished standards, and adjust power to the laser to enhance reader performance without violating prevalent safety standards. Dual monitors are used to independently monitor the output power of the laser.
摘要翻译：激光功率控制装置在检测到不符合预先制定的标准的操作条件时，会中断电光读取器中使用的激光的电源，并调整激光功率，以提高读取器性能，而不会违反普遍的安全标准。双显示器用于独立监控激光器的输出功率。

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