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1. 发明申请

US20080213904A1 Monitoring drug compliance, food-intake or toxin-intake using non-invasively-read labels 审中-公开
标题翻译：使用非侵入式阅读标签监测药物依从性，食物摄入量或毒素摄入量
公开(公告)号：US20080213904A1
公开(公告)日：2008-09-04
申请号：US11895400
申请日：2007-08-23
申请人： John W. Sliwa , Herbert L. Berman , Bryan T. Oronsky , Carol A. Tosaya
发明人： John W. Sliwa , Herbert L. Berman , Bryan T. Oronsky , Carol A. Tosaya
IPC分类号： G01N33/00 , G01N37/00 , G01N21/64 , F21K2/00
CPC分类号： G01N21/6428 , A61B5/0059 , A61B5/117 , A61B5/1171 , A61B5/411 , G01N21/71 , Y10T436/13
摘要： A system is disclosed for monitoring a property of an ingested or in-taken drug, food, drink or toxic substance, non-invasively or minimally invasively, which can also identify the subject person being monitored, if desired. The system comprises: a means of labeling the substance with a labeling media to have a useful signature indicative of, or bearing a relation to the property; a means to allow the signature to be read non-invasively or minimally invasively; and a means to identify, in any manner, who is being monitored.
摘要翻译：公开了一种系统，用于非侵入式或最低侵入性地监测摄入或摄入的药物，食物，饮料或有毒物质的性质，如果需要，还可以识别被监测的受试者。该系统包括：用标签介质标记物质的手段，以便具有指示或与该财产有关系的有用签名; 允许非侵入性或最小程度地侵入签名的手段; 并且以任何方式识别谁正在被监视的手段。

2. 发明申请

US20100233021A1 Systems and methods to deal with health-relevant fouling or plugging depositions and growths 审中-公开
标题翻译：处理与健康有关的结垢或堵塞沉积和生长的系统和方法
公开(公告)号：US20100233021A1
公开(公告)日：2010-09-16
申请号：US12381423
申请日：2009-03-11
申请人： John W. Sliwa , George W. Keilman , Bryan T. Oronsky , Carol A. Tosaya , Herbert L. Berman
发明人： John W. Sliwa , George W. Keilman , Bryan T. Oronsky , Carol A. Tosaya , Herbert L. Berman
IPC分类号： A61L2/10 , A61L2/03 , A61L2/025 , A61N1/32
CPC分类号： A61M25/0017 , A61B90/70 , A61M27/00 , A61M37/00 , A61M2025/0019 , A61N1/205 , A61N1/32 , A61N1/40
摘要： Disclosed are methods of inhibiting, avoiding or destroying existing, potential or incipient biodeposits, biofilms or pathogens any of (a) in or on a living body including in or on a medical device or implement placed, inserted or insertable in the body, (b) in, on or in contact with an ex vivo bodily tissue or fluid, or (c) in, on or in contact with a medium or matter to be consumed, ingested by or exposed to a living being or entity. Also disclosed are medical devices, implements, and prostheses that can be kept in a safe defouled, pathogen-free or pathogen-reduced condition with the help of an electric field(s). Also disclosed are medical or industrial devices, implements, equipment-articles and storage/handling-entities that can be kept in a safely defouled, pathogen-free or pathogen-reduced condition with the help of a membrane or orifice that has one or more of the antifouling or antipathogenic attributes.
摘要翻译：公开了抑制，避免或破坏现有的，潜在的或初期的生物沉积物，生物膜或病原体（a）在生物体内或之上的生物体，包括在放置，插入或插入体内的医疗装置或器具中或之上，（b））在离体身体组织或流体接触或接触时，或（c）在要消费的介质或物质中或与其接触或摄入或暴露于活体或实体时。还公开了医疗装置，器具和假体，其可以在电场的帮助下保持在安全的防污染，无病原体或病原体减少的状态。还公开了医疗或工业装置，器具，设备制品和储存/处理实体，其可以在具有一个或多个以下的膜或孔的帮助下保持在安全脱钩，无病原体或病原体减少的状态防污或抗病原性。

3. 发明申请

US20080140026A1 Acoustically-Aided and/or gel-aided delivery of beneficial gaseous, ionic, unstable, metastable, short-lived or reactive species for medical purposes 审中-公开
标题翻译：用于医疗目的的有利气体，离子，不稳定，亚稳态，短寿命或反应性物质的辅助和/或凝胶辅助递送
公开(公告)号：US20080140026A1
公开(公告)日：2008-06-12
申请号：US12001701
申请日：2007-12-11
申请人： John W. Sliwa , Herbert L. Berman , Bryan T. Oronsky , Carol A. Tosaya
发明人： John W. Sliwa , Herbert L. Berman , Bryan T. Oronsky , Carol A. Tosaya
IPC分类号： A61M35/00
CPC分类号： A61M37/0092 , A61M35/00
摘要： An apparatus and method are provided for delivering to a patient's first bodily site and allowing bodily transport therefrom to one or more second bodily sites of a medically, physiologically, neurologically or other health-beneficial species, the at least one species or species precursor which would normally be one or more of volatile, gaseous, vaporous, sublimating, reactive, unacceptably degradable, toxic, hazardous, metastable or unstable if stored in unprotected ambient atmospheric conditions
摘要翻译：提供了一种装置和方法，用于递送给患者的第一身体部位，并允许从身体转运到医疗，生理学，神经学或其他健康有益物种的一个或多个第二身体部位，所述至少一种物种或物质前体将通常是一种或多种挥发性，气态，气态，升华，反应性，不可接受的降解，有毒，危险，亚稳或不稳定，如果储存在无保护的环境大气条件

4. 发明授权

US08289274B2 Microdroplet-based 3-D volumetric displays utilizing emitted and moving droplet projection screens 有权
标题翻译：基于微滴的3-D体积显示器利用发射和移动的液滴投影屏幕
公开(公告)号：US08289274B2
公开(公告)日：2012-10-16
申请号：US12082064
申请日：2008-04-08
申请人： John W. Sliwa , Carol A. Tosaya
发明人： John W. Sliwa , Carol A. Tosaya
IPC分类号： G09G3/34
CPC分类号： G09G3/34 , G02B27/2271 , G03B21/562 , G03B21/608 , G03B25/00 , H04N13/393
摘要： Volumetric three-dimensional (3-D) graphical or computer displays are disclosed herein that are capable of presenting objects, data, scenes or other visual information in a realistic or solid-like manner, allowing for an unaided observer to observe such static or moving objects from multiple perspectives with natural depth-cues and superior image quality. We utilize in this refined approach moving-screens formed from particulate-arrays and we preferably optically project multiple image sub-slices on each such flying-screen as it passes through the image-volume thereby minimizing particulate mass-flow since only once screen per image-volume is needed to present the several or many necessary slices of each volumetric frame.
摘要翻译：本文公开了体积三维（3-D）图形或计算机显示器，其能够以逼真或实体的方式呈现对象，数据，场景或其他视觉信息，允许无人看管者观察这样的静态或移动具有自然深度线索和卓越图像质量的多个视角的物体。我们利用这种精致的方法，从颗粒阵列形成的移动屏幕，我们优选在每个这样的飞行屏幕上通过图像体积光学投影多个图像子切片，从而最小化颗粒质量流量，因为每个图像只有一次屏幕 - 需要体积来呈现每个体积框架的几个或许多必要的切片。

5. 发明申请

US20100321478A1 Microdroplet-based 3-D volumetric displays utilizing emitted and moving droplet projection screens 有权
标题翻译：基于微滴的3-D体积显示器利用发射和移动的液滴投影屏幕
公开(公告)号：US20100321478A1
公开(公告)日：2010-12-23
申请号：US12082064
申请日：2008-04-08
申请人： John W. Sliwa , Carol A. Tosaya
发明人： John W. Sliwa , Carol A. Tosaya
IPC分类号： H04N13/04
CPC分类号： G09G3/34 , G02B27/2271 , G03B21/562 , G03B21/608 , G03B25/00 , H04N13/393
摘要： Volumetric three-dimensional (3-D) graphical or computer displays are disclosed herein that are capable of presenting objects, data, scenes or other visual information in a realistic or solid-like manner, allowing for an unaided observer to observe such static or moving objects from multiple perspectives with natural depth-cues and superior image quality. We utilize in this refined approach moving-screens formed from particulate-arrays and we preferably optically project multiple image sub-slices on each such flying-screen as it passes through the image-volume thereby minimizing particulate mass-flow since only once screen per image-volume is needed to present the several or many necessary slices of each volumetric frame.
摘要翻译：本文公开了体积三维（3-D）图形或计算机显示器，其能够以逼真或实体的方式呈现对象，数据，场景或其他视觉信息，允许无人看管者观察这样的静态或移动具有自然深度线索和卓越图像质量的多个视角的物体。我们利用这种精致的方法，从颗粒阵列形成的移动屏幕，我们优选在每个这样的飞行屏幕上通过图像体积光学投影多个图像子切片，从而最小化颗粒质量流量，因为每个图像只有一次屏幕 - 需要体积来呈现每个体积框架的几个或许多必要的切片。

6. 发明申请

US20110066083A1 Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy 审中-公开
标题翻译：用于治疗肥胖症或脂肪沉积物或用于递送化妆品或其他身体治疗的超声波装置和方法
公开(公告)号：US20110066083A1
公开(公告)日：2011-03-17
申请号：US12807965
申请日：2010-09-17
申请人： Carol A. Tosaya , Lee Blumenfeld , John W. Sliwa, JR.
发明人： Carol A. Tosaya , Lee Blumenfeld , John W. Sliwa, JR.
IPC分类号： A61N7/00
CPC分类号： A61H23/0245 , A61N7/00 , A61N2007/0008
摘要： A wearable treatment or therapy apparatus for provision of an acoustically enabled or acoustically enhanced treatment or therapy to a patient or treatment subject is provided. Also provided are apparatuses for delivering an acoustic or acoustically-aided therapy or treatment to a patient or treatment-subject.
摘要翻译：提供了一种用于向患者或治疗对象提供声学启用或声学增强治疗或治疗的穿戴式治疗或治疗装置。还提供了用于将声学或声学辅助治疗或治疗递送给患者或治疗对象的装置。

7. 发明申请

US20100160181A1 Cooling, condensation and freezing of atmospheric water or a microfluidic working-material in or on microfluidic devices 审中-公开
标题翻译：微流体装置中或微流体装置上的大气水或微流体工作材料的冷却，冷凝和冷冻
公开(公告)号：US20100160181A1
公开(公告)日：2010-06-24
申请号：US12660545
申请日：2010-03-01
申请人： John W. Sliwa, JR. , Carol A. Tosaya
发明人： John W. Sliwa, JR. , Carol A. Tosaya
IPC分类号： C40B40/00 , B81B7/00 , G01N1/28 , G01N35/10 , C12M1/34 , C12M1/00
CPC分类号： B41J29/377
摘要： Condensation of water from a gas, such as from atmospheric air or other nearby ambient gas, is provided for use in a variety of jetting devices, such as lab-on-a-chip applications. Further embodiments involve the use of frozen liquids, not limited to frozen condensed water, and microcooling of fluidic components or working materials for improved process control and reliability.
摘要翻译：提供来自气体（例如来自大气或其他附近环境气体）的水的冷凝，用于各种喷射装置，例如片上实验室应用。进一步的实施方案涉及使用冷冻液体，不限于冷冻冷凝水，以及使用流体组分或工作材料的显微冷却，以改善工艺控制和可靠性。

8. 发明授权

US07682009B1 Cooling, condensation and freezing of atmospheric water or of a microfluidic working-material in or on microfluidic devices 失效
标题翻译：微流体装置中或微流体装置上的大气水或微流体工作材料的冷却，冷凝和冷冻
公开(公告)号：US07682009B1
公开(公告)日：2010-03-23
申请号：US11141350
申请日：2005-05-31
申请人： John W. Sliwa, Jr. , Carol A. Tosaya
发明人： John W. Sliwa, Jr. , Carol A. Tosaya
IPC分类号： B41J2/17
CPC分类号： B41J29/377
摘要： Condensation of water from a gas, such as from atmospheric air or other nearby ambient gas, is provided for use in a variety of jetting devices, such as inkjet and lab-on-a-chip applications. Further embodiments involve the use of frozen liquids, not limited to frozen condensed water, and microcooling of fluidic components or working materials for improved process control and reliability.
摘要翻译：提供来自气体（例如来自大气或其他附近环境气体）的水的冷凝用于各种喷射装置，例如喷墨和实验室在芯片上的应用。进一步的实施方案涉及使用冷冻液体，不限于冷冻冷凝水，以及使用流体组分或工作材料的显微冷却，以改善工艺控制和可靠性。

9. 发明授权

US07082395B2 Signal injection coupling into the human vocal tract for robust audible and inaudible voice recognition 有权
公开(公告)号：US07082395B2
公开(公告)日：2006-07-25
申请号：US10265468
申请日：2002-10-03
申请人： Carol A. Tosaya , John W. Sliwa, Jr.
发明人： Carol A. Tosaya , John W. Sliwa, Jr.
IPC分类号： G10L15/00
CPC分类号： G10L15/20 , G10L19/08
摘要： A means and method are provided for enhancing or replacing the natural excitation of the human vocal tract by artificial excitation means, wherein the artificially created acoustics present additional spectral, temporal, or phase data useful for (1) enhancing the machine recognition robustness of audible speech or (2) enabling more robust machine-recognition of relatively inaudible mouthed or whispered speech. The artificial excitation (a) may be arranged to be audible or inaudible, (b) may be designed to be non-interfering with another user's similar means, (c) may be used in one or both of a vocal content-enhancement mode or a complimentary vocal tract-probing mode, and/or (d) may be used for the recognition of audible or inaudible continuous speech or isolated spoken commands.

10. 发明授权

US08083707B2 Non-contact damage-free ultrasonic cleaning of implanted or natural structures having moving parts and located in a living body 有权
标题翻译：具有运动部件并位于生物体内的植入式或天然结构的非接触式无损伤超声波清洗
公开(公告)号：US08083707B2
公开(公告)日：2011-12-27
申请号：US10826232
申请日：2004-04-16
申请人： Carol A. Tosaya , John W. Sliwa, Jr.
发明人： Carol A. Tosaya , John W. Sliwa, Jr.
IPC分类号： A61B17/20
CPC分类号： A61B17/22004 , A61B90/37 , A61B2017/00243 , A61B2017/22098
摘要： Ultrasonic, sonic or vibratory energy, delivered non-invasively, minimally invasively or invasively (e.g. surgically), is utilized to provide direct cleaning action at or to the location of the implanted device such as a prosthetic heart valve with undesirable deposits of at least some amount thereon or therein. Such ultra-sound energy may be aided by the use of a drug in association or cooperation with the acoustic irradiation. The “cleaning” acoustic energy may optionally be delivered under the guidance of an imaging modality and may be delivered in a timed or gated manner such that the valve occluders or leaflets are in a preferred position (assuming they are functioning) during exposures.
摘要翻译：超声波，声波或振动能量非侵入性地以最小的侵入性或侵入性（例如外科手术）被使用，以在植入装置的位置处或位置处提供直接清洁作用，例如假体心脏瓣膜，其具有至少一些不期望的沉积在其上或其中。这种超声能量可以通过使用与声辐射相关联或配合的药物来辅助。 “清洁”声能可以任选地在成像模态的指导下传送，并且可以以定时或门控的方式递送，使得在曝光期间，阀封闭器或传单处于优选位置（假设它们正在起作用）。

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