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1. 发明申请

US20050209165A1 4-Biarylyl-1-phenylazetidin-2-ones 失效
标题翻译： 4-二亚苄基-1-苯基氮杂环丁-2-酮
公开(公告)号：US20050209165A1
公开(公告)日：2005-09-22
申请号：US10986570
申请日：2004-11-10
申请人： Eduardo Martinez , John Talley , Stephen Antonelli , Timothy Barden , Regina Lundrigan-Soucy , Wayne Schairer , Jing-Jing Yang , Daniel Zimmer
发明人： Eduardo Martinez , John Talley , Stephen Antonelli , Timothy Barden , Regina Lundrigan-Soucy , Wayne Schairer , Jing-Jing Yang , Daniel Zimmer
IPC分类号： A61K31/337 , A61K31/397 , A61K31/675 , A61K31/69 , A61K31/7052 , A61K45/06 , C07D205/08 , C07D405/10
CPC分类号： C07D205/08 , A61K31/337 , A61K31/397 , A61K45/06 , C07D263/20 , C07D401/04 , C07D405/10 , C07D409/04 , C07D453/02 , C07F7/1804 , C07F9/568 , C07H7/04 , C07H15/203 , A61K2300/00
摘要： 4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula in which represents an aryl or heteroaryl residue; Ar represents an aryl residue; U is a two to six atom chain; and the R's represent substituents.
摘要翻译：公开了可用于治疗高胆固醇血症的4-二苄基-1-苯基氮杂环丁-2-酮。所述化合物具有通式，其中代表芳基或杂芳基残基; Ar表示芳基残基; U是2至6个原子链; R代表取代基。

2. 发明申请

US20090186834A1 DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS 审中-公开
标题翻译：二氢胆固醇胆固醇吸收抑制剂
公开(公告)号：US20090186834A1
公开(公告)日：2009-07-23
申请号：US11909482
申请日：2006-03-24
申请人： John Talley , Eduardo Martinez , Daniel Zimmer , Regina Lundrigan
发明人： John Talley , Eduardo Martinez , Daniel Zimmer , Regina Lundrigan
IPC分类号： A61K31/70 , C07D277/00 , A61K31/425 , C07F9/28 , A61K31/675 , A61K31/415 , C07D233/00 , C07D263/00 , A61K31/42 , A61K31/40 , C07D405/00 , C07D207/00 , A61K31/397 , C07D205/00 , C07H15/00
CPC分类号： C07D263/24 , C07D205/04 , C07D205/06 , C07D205/08 , C07D233/32 , C07D283/00 , C07D413/10 , C07D413/12
摘要： Various azetidinone, pyrrolidine, imidazolidine, and oxazolidine derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described.
摘要翻译：还描述了各种氮杂环丁酮，吡咯烷，咪唑烷和恶唑烷衍生物，含有这些化合物的药物组合物和使用这些化合物治疗疾病的方法也是如此。还描述了其它实施例。

3. 发明授权

US07320972B2 4-Biarylyl-1-phenylazetidin-2-ones 失效
标题翻译： 4-二亚苄基-1-苯基氮杂环丁-2-酮
公开(公告)号：US07320972B2
公开(公告)日：2008-01-22
申请号：US10986570
申请日：2004-11-10
申请人： Eduardo Martinez , John J. Talley , Stephen Antonelli , Timothy C. Barden , Regina Lundrigan-Soucy , Wayne C. Schairer , Jing-Jing Yang , Daniel P. Zimmer , Brian Cali , Mark G. Currie , Peter S. Yorgey
发明人： Eduardo Martinez , John J. Talley , Stephen Antonelli , Timothy C. Barden , Regina Lundrigan-Soucy , Wayne C. Schairer , Jing-Jing Yang , Daniel P. Zimmer , Brian Cali , Mark G. Currie , Peter S. Yorgey
IPC分类号： C07D205/08 , A61K31/397 , A61K31/7052 , A61P3/06 , A61P9/10
CPC分类号： C07D205/08 , A61K31/337 , A61K31/397 , A61K45/06 , C07D263/20 , C07D401/04 , C07D405/10 , C07D409/04 , C07D453/02 , C07F7/1804 , C07F9/568 , C07H7/04 , C07H15/203 , A61K2300/00
摘要： 4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula in which represents an aryl or heteroaryl residue; Ar represents an aryl residue; U is a two to six atom chain; and the R's represent substituents.
摘要翻译：公开了可用于治疗高胆固醇血症的4-二苄基-1-苯基氮杂环丁-2-酮。所述化合物具有通式，其中代表芳基或杂芳基残基; Ar表示芳基残基; U是2至6个原子链; R代表取代基。

4. 发明申请

US20070072812A1 Quaternary salt derivatives of 1,4-diphenylazetidin-2-ones 审中-公开
标题翻译： 1,4-二苯并氮杂环丁-2-酮的季盐衍生物
公开(公告)号：US20070072812A1
公开(公告)日：2007-03-29
申请号：US10569557
申请日：2004-08-25
申请人： Eduardo Martinez , John Talley
发明人： Eduardo Martinez , John Talley
IPC分类号： A61K31/7052 , A61K31/498 , A61K31/397 , C07D403/14
CPC分类号： C07D205/08 , C07D405/12 , C07D453/02 , C07D487/08
摘要： Quaternary salt derivatives of 1,4-diphenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formulae as well as isomers of these formulae.
摘要翻译：公开了可用于治疗高胆固醇血症的1,4-二苯基氮杂环丁-2-酮的季盐衍生物。这些化合物具有通式以及这些式的异构体。

5. 发明申请

US20070161577A1 Tethered dimers and trimers of 1,4-diphenylazetidin-2-ones 审中-公开
标题翻译： 1,4-二苯并氮杂环丁-2-酮的连接二聚体和三聚体
公开(公告)号：US20070161577A1
公开(公告)日：2007-07-12
申请号：US10569561
申请日：2004-08-27
申请人： Eduardo Martinez , John Talley
发明人： Eduardo Martinez , John Talley
IPC分类号： A61K31/7052 , A61K31/397 , C07D205/02 , C07D403/02
CPC分类号： C07D205/08 , C07D405/12 , C07D471/08
摘要： Derivatives of 1,4-diphenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula
摘要翻译：公开了可用于治疗高胆固醇血症的1,4-二苯基氮杂环丁-2-酮的衍生物。该化合物具有通式

6. 发明申请

US20110050252A1 AUTOMATIC CHARACTERIZATION OF AN ACTUATOR BASED ON CAPACITANCE MEASUREMENT 有权
标题翻译：基于电容测量的执行器的自动表征
公开(公告)号：US20110050252A1
公开(公告)日：2011-03-03
申请号：US12860063
申请日：2010-08-20
申请人： Eduardo Martinez , Christian Jimenez , Jose Ibanez-Climent , Colm Donovan
发明人： Eduardo Martinez , Christian Jimenez , Jose Ibanez-Climent , Colm Donovan
IPC分类号： G01R27/26
CPC分类号： G05D3/00 , B81C99/005 , H01L41/042
摘要： An apparatus and method for determining characterizing attributes of an actuator is provided. An actuator may be moved to a maximum capacitance position. At the maximum capacitance position, an initial measurement of the actuator capacitance is made. The actuator is moved a predetermined increment toward a first extreme position, and the actuator capacitance is again measured. If the capacitance changed by a threshold amount, the signal preceding the signal that caused the actuator to move is recorded as an approximate response curve end point, or the first extreme position. The actuator is again moved a predetermined increment toward a second extreme position. After each move, the capacitance is measured. If it is determined the capacitance did change by a threshold amount from the previously measured capacitance, the signal related to the previously measured capacitance is recorded as an approximate response curve end point, or the second extreme position.
摘要翻译：提供了一种用于确定致动器的特征属性的装置和方法。致动器可以移动到最大电容位置。在最大电容位置，进行致动器电容的初始测量。致动器朝向第一极限位置移动预定增量，并再次测量致动器电容。如果电容变化了阈值，则将导致执行器移动的信号前面的信号记录为近似响应曲线终点或第一极限位置。致动器再次向第二极限位置移动预定增量。每次移动后，测量电容。如果确定电容确实从先前测量的电容改变阈值量，则将与先前测量的电容相关的信号记录为近似响应曲线终点或第二极限位置。

7. 发明授权

US5438656A Raster shape synthesis by direct multi-level filling 失效
标题翻译：光栅形状合成通过直接多级填充
公开(公告)号：US5438656A
公开(公告)日：1995-08-01
申请号：US70135
申请日：1993-06-01
申请人： Jacobo Valdes , Eduardo Martinez
发明人： Jacobo Valdes , Eduardo Martinez
IPC分类号： B41J2/485 , G06T11/20 , G06T11/40 , G09G5/28 , G06T11/00
CPC分类号： G09G5/28 , G06T11/40
摘要： A method of synthesizing multi-level raster shapes directly from outlines describing ideal shapes is disclosed. A raster shape suitable for approximating the ideal shape in a raster display device is synthesized by dividing a plane into a plurality of pixel areas according to a pixel grid, then by representing the shape as one or more arcs in the plane, where the arcs collectively, and in conjunction with an insideness criterium, divide the plane into an inside region and an outside region, and then by separating the pixels into inside pixels, outside pixels, and boundary pixels. The raster shape comprises coverage values assigned to each pixel in the plane, where inside pixels are assigned a coverage value of 1, outside pixels a coverage value of 0 and the boundary pixels a coverage value between 0 and 1 approximating the degree to which the boundary pixel is covered by the inside of the outline. Initially, boundary pixels are assigned a coverage value of 0 or 1 based on a pixel-coverage criterium, and then it is corrected by a correction value resulting in a coverage value between 0 and 1. The correction value for a pixel might be a numerical value indicating the fraction of the pixel covered by the correction region; the correction value may also depend on the geometry of the correction region represented by the valve and the region's location within the pixel. The correction region of a boundary pixel is the signed difference between the region represented by the initial coverage value assigned to the pixel and the actual region of the pixel covered by the inside of the outline.
摘要翻译：公开了直接从描述理想形状的轮廓合成多级光栅形状的方法。通过根据像素网格将平面划分为多个像素区域，然后通过将该形状表示为平面中的一个或多个弧来合成光栅显示设备中适合于近似理想形状的光栅形状，其中弧线集中，并结合一个绝对标准，将平面分成内部区域和外部区域，然后将像素分离成内部像素，外部像素和边界像素。栅格形状包括分配给平面中的每个像素的覆盖值，其中内部像素被分配覆盖值1，外部像素覆盖值为0，边界像素覆盖值在0和1之间近似于边界的程度像素被轮廓的内部覆盖。首先，边界像素根据像素覆盖率标准分配0或1的覆盖值，然后通过校正值来校正，导致0和1之间的覆盖值。像素的校正值可以是数字指示由校正区域覆盖的像素的分数的值; 校正值也可以取决于由阀表示的校正区域的几何形状和区域在像素内的位置。边界像素的校正区域是由分配给像素的初始覆盖值和由轮廓内部覆盖的像素的实际区域表示的区域之间的有符号差。

8. 发明授权

US5319358A Method and apparatus for minimizing the visual degradation of digital typefaces 失效
标题翻译：用于最小化数字字体的视觉退化的方法和装置
公开(公告)号：US5319358A
公开(公告)日：1994-06-07
申请号：US850245
申请日：1992-03-11
申请人： Eduardo Martinez , May Kao
发明人： Eduardo Martinez , May Kao
IPC分类号： G06F3/153 , G06K15/02 , G09G1/14 , G09G5/24 , G09G5/28 , G09G5/26
CPC分类号： G09G5/28 , G06K15/02 , G06T11/203 , G09G1/14 , G06K2215/0034 , Y10S345/948
摘要： A method and apparatus for minimizing the visual degradation of a typeface wherein the need for the manual input of skilled technicians is eliminated and the important visual components of each character and the relationship of the visual components of each character with the other characters of the typeface are preserved. The characters are analyzed to determine the visual components in the horizontal and vertical direction which comprise each character and the priority of adjustment. Using the visual components determined, starting with the highest priority component, the coordinates describing each character are adjusted according to rules which are dependent upon whether the strokes formed are oriented in the horizontal or vertical direction. The adjustment of the lower priority visual components is dependent on the previously aligned components. The important visual components in the diagonal direction are subsequently adjusted in accordance with similar sized visual components in the horizontal and vertical direction wherein the dimensions of the adjusted horizontal and vertical components are maintained.
摘要翻译：用于最小化字体的视觉退化的方法和装置，其中消除了熟练技术人员的手动输入的需要，并且每个角色的重要视觉部件以及每个角色的视觉部件与字体的其他字符之间的关系是保存分析字符以确定包括每个字符和调整优先级的水平和垂直方向上的视觉分量。使用从最高优先级分量开始的视觉部件，描述每个角色的坐标根据依赖于所形成的笔画是否沿水平或垂直方向取向的规则来调整。较低优先级的可视组件的调整取决于先前对齐的组件。随后根据水平和垂直方向上相似尺寸的视觉部件调整对角线方向上的重要视觉部件，其中维持经调节的水平和垂直分量的尺寸。

9. 发明授权

US5274365A Method and apparatus for minimizing the visual degradation of digital typefaces-character analysis 失效
标题翻译：用于最小化数字字体视觉退化的方法和装置 - 字符分析
公开(公告)号：US5274365A
公开(公告)日：1993-12-28
申请号：US846213
申请日：1992-03-04
申请人： Eduardo Martinez , May Kao
发明人： Eduardo Martinez , May Kao
IPC分类号： G06K15/02 , G09G1/14 , G09G5/26
CPC分类号： G06K15/02 , G09G1/14 , G06K2215/0034 , Y10S345/948
摘要： A method and apparatus for minimizing the visual degradation of a typeface wherein the need for the manual input of skilled technicians is eliminated and the important visual components of each character and the relationship of the visual components of each character with the other characters of the typeface are preserved. The characters are analyzed to determine the visual components in the horizontal and vertical direction which comprise each character and the priority of adjustment. Using the visual components determined, starting with the highest priority component, the coordinates describing each character are adjusted according to rules which are dependent upon whether the strokes formed are oriented in the horizontal or vertical direction. The adjustment of the lower priority visual components is dependent on the previously aligned components. The important visual components in the diagonal direction are subsequently adjusted in accordance with similar sized visual components in the horizontal and vertical direction wherein the dimensions of the adjusted horizontal and vertical components are maintained.
摘要翻译：用于最小化字体的视觉退化的方法和装置，其中消除了熟练技术人员的手动输入的需要，并且每个角色的重要视觉部件以及每个角色的视觉部件与字体的其他字符之间的关系是保存分析字符以确定包括每个字符和调整优先级的水平和垂直方向上的视觉分量。使用从最高优先级分量开始的视觉部件，描述每个角色的坐标根据依赖于所形成的笔画是否沿水平或垂直方向取向的规则来调整。较低优先级的可视组件的调整取决于先前对齐的组件。随后根据水平和垂直方向上相似尺寸的视觉部件调整对角线方向上的重要视觉部件，其中维持经调节的水平和垂直分量的尺寸。

10. 发明申请

US20150128327A1 POCKET SYSTEM FOR AN AUDIO PLAYER 审中-公开
标题翻译：用于音乐播放器的口袋系统
公开(公告)号：US20150128327A1
公开(公告)日：2015-05-14
申请号：US14467540
申请日：2014-08-25
申请人： Eduardo Martinez
发明人： Eduardo Martinez
IPC分类号： A41D27/20 , A41D1/04 , A41D1/02 , A41D1/00
CPC分类号： A41D27/205 , A41D1/002 , A41D2300/326
摘要： A pocket system for wearing an audio player comprising a pocket on a garment, where the pocket is capable of securely storing the audio player during use; and an eyelet opening above the pocket, where the eyelet opening channels an ear phone wire from the audio player toward a neck portion of the garment. The garment includes a set of loops on a top surface of the garment, where the set of loops guide the ear phone wire from the audio player. Further, the garment may include a hole within a neck portion, where the hole threads the ear phone wire.
摘要翻译：一种用于佩戴音频播放器的口袋系统，包括衣服上的口袋，其中口袋能够在使用期间安全地存储音频播放器; 以及在口袋上方的孔眼，其中孔眼开口将耳机电话线从音频播放器通向衣服的颈部。该服装包括在衣服的顶部表面上的一组环，其中一组环从音频播放器引导耳机线。此外，衣服可以包括在颈部内的孔，其中孔与耳机线接合。

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