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1. 发明授权

US10413652B2 Systems and methods for use and control of an automated separator with adsorption columns 有权
公开(公告)号：US10413652B2
公开(公告)日：2019-09-17
申请号：US14110587
申请日：2011-04-13
申请人： John T. Foley , Jonathan Prendergast , Lan T. Nguyen , Brian C. Case
发明人： John T. Foley , Jonathan Prendergast , Lan T. Nguyen , Brian C. Case
IPC分类号： A61M1/36
摘要： Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system.

2. 发明申请

US20140291248A1 SYSTEMS AND METHODS FOR USE AND CONTROL OF AN AUTOMATED SEPARATOR WITH ADSORPTION COLUMNS 有权
标题翻译：具有吸附柱的自动分离器的使用和控制的系统和方法
公开(公告)号：US20140291248A1
公开(公告)日：2014-10-02
申请号：US14110587
申请日：2011-04-13
申请人： John T. Foley , Jonathan Prendergast , Lan T. Nguyen , Brian C. Case
发明人： John T. Foley , Jonathan Prendergast , Lan T. Nguyen , Brian C. Case
IPC分类号： A61M1/36
CPC分类号： A61M1/362 , A61M1/3639 , A61M1/3641 , A61M1/3663 , A61M1/3679 , A61M1/3693 , A61M1/3696
摘要： Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system.
摘要翻译：提供血液处理系统和方法用于组合血液分离系统和吸附装置。血液分离系统被配置为将血液成分与血液分离，而吸附装置构造成接收至少一部分分离的血液成分并进行处理。血液分离系统包括流体流动元件和控制器。流体流动元件构造成使分离的血液成分流入吸附装置。控制器至少部分地基于一个或多个处理参数来控制流体流动元件。处理参数包括流入吸附装置的分离的血液成分的最大流量，流入吸附装置的分离的血液成分的最大压力和/或系统位置的流体体积。

3. 发明授权

US08852140B2 System and method for adjustment of blood separation procedure parameters 有权
标题翻译：血液分离手术参数调整系统及方法
公开(公告)号：US08852140B2
公开(公告)日：2014-10-07
申请号：US13345305
申请日：2012-01-06
申请人： John W. Barry, Jr. , Brian C. Case , Lan T. Nguyen
发明人： John W. Barry, Jr. , Brian C. Case , Lan T. Nguyen
IPC分类号： B01D17/12 , B01D17/00 , B01D43/00 , A61M1/36
CPC分类号： A61M1/3693 , A61M1/0209 , A61M1/3672 , A61M2202/0427
摘要： Systems and methods are provided for automatically adjusting the operational parameters of a blood separation procedure. A blood separation device has an inlet for passing fluid thereinto and an outlet for removing fluid therefrom. A pump system is provided for moving fluid into and out of the device. In use, blood is conveyed into the device, where platelets are separated from at least a portion of the blood. A controller determines the amount of platelets in the device. Based at least in part on the amount of platelets in the device, corrective action is taken to avoid platelet aggregation in the device. The corrective action may be conveying an elevated amount of anticoagulant into the blood and/or the device and may be initiated when the determined amount of platelets approaches, meets, or exceeds a threshold predicted likelihood of platelet aggregation.
摘要翻译：提供了用于自动调整血液分离程序的操作参数的系统和方法。血液分离装置具有用于使流体流入的入口和用于从其中除去流体的出口。提供用于将流体移入和移出设备的泵系统。在使用中，将血液输送到装置中，其中血小板与至少一部分血液分离。控制器确定设备中血小板的量。至少部分地基于装置中的血小板的量，采取纠正措施以避免装置中的血小板聚集。纠正措施可能是将升高量的抗凝血剂输送到血液和/或装置中，并且可以在所确定的血小板接近，满足或超过血小板聚集的阈值预测可能性时开始。

4. 发明申请

US20120297255A1 SYSTEM AND METHOD TO BETTER ASSURE CORRECT USE OF PRE-PROGRAMMED MEDICAL DEVICES 审中-公开
标题翻译：更好地确保预编程医疗设备的正确使用的系统和方法
公开(公告)号：US20120297255A1
公开(公告)日：2012-11-22
申请号：US13110520
申请日：2011-05-18
申请人： Brian C. Case , Lan T. Nguyen
发明人： Brian C. Case , Lan T. Nguyen
IPC分类号： G06F11/07
CPC分类号： G16H40/60 , A61B34/10 , A61M1/34 , A61M1/3403 , A61M2205/33 , A61M2205/3334 , G06F19/00 , G06F21/31 , G08B3/10 , G08B5/22 , G16H10/60 , H05K999/99
摘要： Systems and methods are provided for performing a medical procedure with respect to a subject. A data storage location of the system is pre-programmed with a plurality of subject data entries, each having subject-specific information associated with it. A user interface receives an identity input from a subject, which corresponds to the identity of the subject. A controller is associated with the database and the user interface, and is programmed to compare the identity input to the subject data entries. If the identity input corresponds to the subject-specific information of a subject data entry, the controller commands a treatment device to perform a medical procedure with respect to the subject. Otherwise, if the identity input does not correspond to the subject-specific information of any of the subject data entries, the controller generates an error signal which prevents the performance of the medical procedure with respect to the subject.
摘要翻译：提供了用于执行关于受试者的医疗程序的系统和方法。系统的数据存储位置用多个对象数据条目进行预编程，每个对象数据条目具有与其相关联的对象特定信息。用户界面从对象接收与被摄体的身份相对应的身份输入。控制器与数据库和用户界面相关联，并被编程为将身份输入与主题数据条目进行比较。如果身份输入对应于对象数据条目的被摄体特定信息，则控制器命令治疗装置对被摄体进行医疗处理。否则，如果身份输入不对应于任何主题数据条目的主题特定信息，则控制器产生阻止相对于被摄体执行医疗程序的错误信号。

5. 发明申请

US20120175313A1 SYSTEM AND METHOD FOR ADJUSTMENT OF BLOOD SEPARATION PROCEDURE PARAMETERS 有权
标题翻译：用于调节血液分离程序参数的系统和方法
公开(公告)号：US20120175313A1
公开(公告)日：2012-07-12
申请号：US13345305
申请日：2012-01-06
申请人： John W. Barry, JR. , Brian C. Case , Lan T. Nguyen
发明人： John W. Barry, JR. , Brian C. Case , Lan T. Nguyen
IPC分类号： B01D17/12 , B01D43/00 , B01D17/00
CPC分类号： A61M1/3693 , A61M1/0209 , A61M1/3672 , A61M2202/0427
摘要： Systems and methods are provided for automatically adjusting the operational parameters of a blood separation procedure. A blood separation device has an inlet for passing fluid thereinto and an outlet for removing fluid therefrom. A pump system is provided for moving fluid into and out of the device. In use, blood is conveyed into the device, where platelets are separated from at least a portion of the blood. A controller determines the amount of platelets in the device. Based at least in part on the amount of platelets in the device, corrective action is taken to avoid platelet aggregation in the device. The corrective action may be conveying an elevated amount of anticoagulant into the blood and/or the device and may be initiated when the determined amount of platelets approaches, meets, or exceeds a threshold predicted likelihood of platelet aggregation.
摘要翻译：提供了用于自动调整血液分离程序的操作参数的系统和方法。血液分离装置具有用于使流体流入的入口和用于从其中除去流体的出口。提供用于将流体移入和移出设备的泵系统。在使用中，将血液输送到装置中，其中血小板与至少一部分血液分离。控制器确定设备中血小板的量。至少部分地基于装置中的血小板的量，采取纠正措施以避免装置中的血小板聚集。纠正措施可能是将升高量的抗凝血剂输送到血液和/或装置中，并且可以在所确定的血小板接近，满足或超过血小板聚集的阈值预测可能性时开始。

6. 发明申请

US20120041777A1 MOBILE APPLICATIONS FOR BLOOD CENTERS 审中-公开
标题翻译：用于血液中心的移动应用程序
公开(公告)号：US20120041777A1
公开(公告)日：2012-02-16
申请号：US13209161
申请日：2011-08-12
申请人： Brian C. Case , Jonathan Prendergast , John W. Barry, JR. , Kyungyoon Min , William H. Cork , Daryl Richard Calhoun , Christine M. Larson
发明人： Brian C. Case , Jonathan Prendergast , John W. Barry, JR. , Kyungyoon Min , William H. Cork , Daryl Richard Calhoun , Christine M. Larson
IPC分类号： G06Q10/08 , G06Q50/22
CPC分类号： G16H40/63 , G06F19/3418 , G06Q10/087 , G06Q10/1093 , G06Q50/22 , G06T11/206 , G16H10/60
摘要： Certain examples provide systems, methods, and apparatus to provide information regarding blood collection instruments via a mobile device. An example method for blood collection instrument management includes providing a graphical representation of one or more blood collection instruments with a visual indication of a status for each instrument. The graphical representation is to visually convey information regarding each of the one or more blood collection instruments and is selectable by a user to provide additional information regarding each of the one or more blood collection instruments. The method includes facilitating access to troubleshoot and interact with the one or more blood collection instruments via the mobile device. The method includes dynamically updating the status for each instrument via communication between the mobile device and one or more blood collection facilities at which the one or more blood collection instruments are located.
摘要翻译：某些实例提供了通过移动设备提供关于采血仪器的信息的系统，方法和装置。用于采血仪器管理的示例性方法包括提供一个或多个采血器具的图形表示，其具有每个器械的状态的视觉指示。图形表示是视觉地传达关于一个或多个采血器具中的每一个的信息，并且可由用户选择以提供关于一个或多个采血器械中的每一个的附加信息。该方法包括便利访问以经由移动设备对一个或多个采血器具进行故障排除和交互。该方法包括通过移动设备与一个或多个采血设备所在的一个或多个血液采集设备之间的通信动态地更新每个仪器的状态。

7. 发明申请

US20120038651A1 MOBILE APPLICATIONS FOR BLOOD CENTERS 有权
标题翻译：用于血液中心的移动应用程序
公开(公告)号：US20120038651A1
公开(公告)日：2012-02-16
申请号：US13209151
申请日：2011-08-12
申请人： Brian C. Case , Jonathan Prendergast , John W. Barry, JR. , Christopher D. Gassman
发明人： Brian C. Case , Jonathan Prendergast , John W. Barry, JR. , Christopher D. Gassman
IPC分类号： G06T11/20
CPC分类号： G16H40/63 , G06F19/00 , G06F19/3418 , G06Q10/087 , G06Q10/1093 , G06Q50/22 , G06T11/206 , G16H10/60
摘要： Certain examples provide systems, methods, and apparatus to provide information regarding blood donation. Certain examples include a method for providing blood collection information to a donor. The method includes displaying a graphical representation of a donor's donation progress toward a goal for blood component collection to a donor via an executable application icon on a mobile device. The graphical representation is to provide a visual indication of the donor's donation progress toward a goal. The donor's donation progress toward the goal is based on data from a donation facility provided to the mobile device and is displayed via the graphical representation without the donor executing the application. The method includes facilitating access to additional blood donation information for the donor by executing the application via the graphical representation on the mobile device. The method includes facilitating donor action with respect to the blood donation information via the mobile device.
摘要翻译：某些例子提供了提供有关献血信息的系统，方法和装置。某些实例包括用于向供体提供血液采集信息的方法。该方法包括通过移动设备上的可执行应用程序图标向献血者显示献血者捐赠进展的向血液成分收集的目标的图示。图形表示是提供捐赠者向目标进行捐赠进展的视觉指示。捐助者对目标的捐赠进展是基于提供给移动设备的捐赠设施的数据，并且通过图形表示显示，而捐助者没有执行应用程序。该方法包括通过经由移动设备上的图形表示来执行应用来促进对供体的附加献血信息的访问。该方法包括促进通过移动设备的献血信息的供体动作。

8. 发明授权

US09533089B2 Centrifugation system with red blood cell barrier 有权
标题翻译：具有红细胞屏障的离心系统
公开(公告)号：US09533089B2
公开(公告)日：2017-01-03
申请号：US14008651
申请日：2012-03-28
申请人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
发明人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
IPC分类号： A61M1/36 , B04B5/04
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/128 , A61M2205/3331 , A61M2205/3337 , B04B5/0442 , B04B2005/045 , C12N5/0634 , C12N5/0641 , C12N5/0644
摘要： Centrifugation systems and methods are provided for separating blood into its constituent parts. Inner and outer walls of a centrifuge each include a projection which extends toward the other wall. A separation chamber is received in the centrifuge between the walls, with the chamber including an inlet port for flowing blood into the chamber, a plasma outlet port for flowing plasma out of the chamber, and a red cell outlet port for flowing red blood cells out of the chamber. With the chamber received in the centrifuge between the walls, the first projection extends into the path of separated blood components flowing toward the plasma outlet port and prevents cellular blood components from flowing into the plasma outlet port. The second projection extends into the path of separated blood components flowing toward the red cell outlet port and prevents plasma from flowing into the red cell outlet port.
摘要翻译：提供离心系统和方法用于将血液分离成其组成部分。离心机的内壁和外壁各自包括朝向另一壁延伸的突起。分离室被容纳在离心机之间的壁之间，其中腔室包括用于使血液进入腔室的入口端口，用于使等离子体流出腔室的等离子体出口和用于使红细胞流出的红细胞出口的房间。随着室中的离心机容纳在壁之间，第一突出部延伸到分离的血液成分流向等离子体出口端口的路径中，并防止细胞血液成分流入等离子体出口。第二突出部延伸到朝向红细胞出口流动的分离的血液成分的路径中，并防止血浆流入红细胞出口。

9. 发明申请

US20140045671A1 CENTRIFUGATION SYSTEM WITH RED BLOOD CELL BARRIER 有权
标题翻译：红血球细胞分离系统
公开(公告)号：US20140045671A1
公开(公告)日：2014-02-13
申请号：US14008651
申请日：2012-03-28
申请人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
发明人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
IPC分类号： A61M1/36
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/128 , A61M2205/3331 , A61M2205/3337 , B04B5/0442 , B04B2005/045 , C12N5/0634 , C12N5/0641 , C12N5/0644
摘要： Centrifugation systems and methods are provided for separating blood into its constituent parts. Inner and outer walls of a centrifuge each include a projection which extends toward the other wall. A separation chamber is received in the centrifuge between the walls, with the chamber including an inlet port for flowing blood into the chamber, a plasma outlet port for flowing plasma out of the chamber, and a red cell outlet port for flowing red blood cells out of the chamber. With the chamber received in the centrifuge between the walls, the first projection extends into the path of separated blood components flowing toward the plasma outlet port and prevents cellular blood components from flowing into the plasma outlet port. The second projection extends into the path of separated blood components flowing toward the red cell outlet port and prevents plasma from flowing into the red cell outlet port.
摘要翻译：提供离心系统和方法用于将血液分离成其组成部分。离心机的内壁和外壁各自包括朝向另一壁延伸的突起。分离室被容纳在离心机之间的壁之间，其中腔室包括用于使血液进入腔室的入口端口，用于使等离子体流出腔室的等离子体出口和用于使红细胞流出的红细胞出口的房间。随着室中的离心机容纳在壁之间，第一突出部延伸到分离的血液成分流向等离子体出口端口的路径中，并防止细胞血液成分流入等离子体出口。第二突出部延伸到朝向红细胞出口流动的分离的血液成分的路径中，并防止血浆流入红细胞出口。

10. 发明授权

US08676600B2 Mobile applications for blood centers 有权
标题翻译：血液中心移动应用
公开(公告)号：US08676600B2
公开(公告)日：2014-03-18
申请号：US13209151
申请日：2011-08-12
申请人： Brian C. Case , Jonathan Prendergast , John W. Barry, Jr. , Christopher D. Gassman
发明人： Brian C. Case , Jonathan Prendergast , John W. Barry, Jr. , Christopher D. Gassman
IPC分类号： G06Q10/00
CPC分类号： G16H40/63 , G06F19/00 , G06F19/3418 , G06Q10/087 , G06Q10/1093 , G06Q50/22 , G06T11/206 , G16H10/60
摘要： Certain examples provide systems, methods, and apparatus to provide information regarding blood donation. Certain examples include a method for providing blood collection information to a donor. The method includes displaying a graphical representation of a donor's donation progress toward a goal for blood component collection to a donor via an executable application icon on a mobile device. The graphical representation is to provide a visual indication of the donor's donation progress toward a goal. The donor's donation progress toward the goal is based on data from a donation facility provided to the mobile device and is displayed via the graphical representation without the donor executing the application. The method includes facilitating access to additional blood donation information for the donor by executing the application via the graphical representation on the mobile device. The method includes facilitating donor action with respect to the blood donation information via the mobile device.
摘要翻译：某些例子提供了提供有关献血信息的系统，方法和装置。某些实例包括用于向供体提供血液采集信息的方法。该方法包括通过移动设备上的可执行应用程序图标向献血者显示献血者捐赠进展的向血液成分收集的目标的图示。图形表示是提供捐赠者向目标进行捐赠进展的视觉指示。捐助者对目标的捐赠进展是基于提供给移动设备的捐赠设施的数据，并且通过图形表示显示，而捐助者不执行应用程序。该方法包括通过经由移动设备上的图形表示来执行应用来促进对供体的附加献血信息的访问。该方法包括促进通过移动设备的献血信息的供体动作。

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