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1. 发明申请

US20050245924A1 Ion eluting tuna device 有权
标题翻译：离子洗脱金枪鱼装置
公开(公告)号：US20050245924A1
公开(公告)日：2005-11-03
申请号：US10836467
申请日：2004-04-30
申请人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
发明人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B2018/00077 , A61B2018/00148 , A61B2018/1472
摘要： Delivery elements, including needle electrodes and sheaths of tissue ablation devices, containing a conductivity-enhancing agent are discussed. The delivery elements contain a body member and optionally one or more coating layers. The conductivity-enhancing agent is disposed on or in the body member and/or at least one of the one or more coating layers. The conductivity-enhancing agent is capable of eluting from the delivery element when the delivery element is contacted with bodily tissue or fluid and increases conductivity of the tissue, making tissue ablation more efficient.
摘要翻译：讨论了包含导电性增强剂的递送元件，包括组织消融装置的针电极和护套。递送元件包含主体部件和可选的一个或多个涂层。导电性增强剂设置在主体部件中和/或主体部件和/或一个或多个涂层中的至少一个上。当递送元件与身体组织或流体接触并且增加组织的电导率时，导电性增强剂能够从递送元件洗脱，从而使组织消融更有效率。

2. 发明申请

US20080077125A1 TUNA DEVICE WITH INTEGRATED SALINE RESERVOIR 有权
标题翻译： TUNA设备与集成的盐水储存
公开(公告)号：US20080077125A1
公开(公告)日：2008-03-27
申请号：US11950751
申请日：2007-12-05
申请人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
发明人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/1472 , A61B2018/1475
摘要： Methods and apparatus for ablating a target tissue are discussed. Such methods and apparatus include those that simplify tissue ablation. For example, a tissue ablation device having an actuator, such as a trigger mechanism, coupled to a power source and an electrode is discussed. A single step of engaging the actuator causes the electrode to be introduced into the target tissue and causes energy to be delivered from the power supply to the tissue via the electrode. By way of additional example, a tissue ablation device having an actuator coupled to a fluid source and an electrode is discussed. A single step of engaging the actuator causes conductive fluid to flow from the fluid source to the target tissue location and causes the electrode to be introduced to the target tissue location. The fluid source may be a conductive fluid, such as saline, which may increase the efficiency of ablation. Various other configurations and methods that simplify tissue ablation are also discussed.
摘要翻译：讨论了用于烧蚀靶组织的方法和装置。这些方法和装置包括简化组织消融的方法和装置。例如，讨论了具有耦合到电源和电极的诸如触发机构的致动器的组织消融装置。使执行器接合的一个步骤使得电极被引入目标组织中，并且通过电极将能量从电源传送到组织。作为另外的示例，讨论了具有耦合到流体源和电极的致动器的组织消融装置。使致动器接合的一个步骤导致导电流体从流体源流动到目标组织位置，并且使电极被引入目标组织位置。流体源可以是诸如盐水的导电流体，其可以提高消融效率。还讨论了简化组织消融的各种其它配置和方法。

3. 发明申请

US20060229601A1 Ion Eluting TUNA Device 审中-公开
标题翻译：离子洗脱TUNA设备
公开(公告)号：US20060229601A1
公开(公告)日：2006-10-12
申请号：US11419662
申请日：2006-05-22
申请人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
发明人： John Swoyer , Yelena Tropsha , Julie Woessner , Mark Christopherson
IPC分类号： A61B18/18 , A61N1/00
CPC分类号： A61B18/14 , A61B2018/00077 , A61B2018/00148 , A61B2018/1472
摘要： Delivery elements, including needle electrodes and sheaths of tissue ablation devices, containing a conductivity-enhancing agent are discussed. The delivery elements contain a body member and optionally one or more coating layers. The conductivity-enhancing agent is disposed on or in the body member and/or at least one of the one or more coating layers. The conductivity-enhancing agent is capable of eluting from the delivery element when the delivery element is contacted with bodily tissue or fluid and increases conductivity of the tissue, making tissue ablation more efficient.
摘要翻译：讨论了包含导电性增强剂的递送元件，包括组织消融装置的针电极和护套。递送元件包含主体部件和可选的一个或多个涂层。导电性增强剂设置在主体部件中和/或主体部件和/或一个或多个涂层中的至少一个上。当递送元件与身体组织或流体接触并且增加组织的电导率时，导电性增强剂能够从递送元件洗脱，从而使组织消融更有效率。

4. 发明申请

US20060036235A1 TUNA device with integrated saline resevoir 有权
标题翻译： TUNA装置，集成盐水储存
公开(公告)号：US20060036235A1
公开(公告)日：2006-02-16
申请号：US10915310
申请日：2004-08-10
申请人： John Swoyer , Yelena Trophsa , Julie Woessner , Mark Christopherson
发明人： John Swoyer , Yelena Trophsa , Julie Woessner , Mark Christopherson
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/1472 , A61B2018/1475
摘要： Methods and apparatus for ablating a target tissue are discussed. Such methods and apparatus include those that simplify tissue ablation. For example, a tissue ablation device having an actuator, such as a trigger mechanism, coupled to a power source and an electrode is discussed. A single step of engaging the actuator causes the electrode to be introduced into the target tissue and causes energy to be delivered from the power supply to the tissue via the electrode. By way of additional example, a tissue ablation device having an actuator coupled to a fluid source and an electrode is discussed. A single step of engaging the actuator causes conductive fluid to flow from the fluid source to the target tissue location and causes the electrode to be introduced to the target tissue location. The fluid source may be a conductive fluid, such as saline, which may increase the efficiency of ablation. Various other configurations and methods that simplify tissue ablation are also discussed.
摘要翻译：讨论了用于烧蚀靶组织的方法和装置。这些方法和装置包括简化组织消融的方法和装置。例如，讨论了具有耦合到电源和电极的诸如触发机构的致动器的组织消融装置。使执行器接合的一个步骤使得电极被引入目标组织中，并且通过电极将能量从电源传送到组织。作为另外的示例，讨论了具有耦合到流体源和电极的致动器的组织消融装置。使致动器接合的一个步骤导致导电流体从流体源流动到目标组织位置，并且使电极被引入目标组织位置。流体源可以是诸如盐水的导电流体，其可以提高消融效率。还讨论了简化组织消融的各种其它配置和方法。

5. 发明申请

US20050245923A1 Biopolar virtual electrode for transurethral needle ablation 审中-公开
标题翻译：用于经尿道针消融的Biopolar虚拟电极
公开(公告)号：US20050245923A1
公开(公告)日：2005-11-03
申请号：US10835193
申请日：2004-04-29
申请人： Mark Christopherson , Martin Gerber , Julie Woessner
发明人： Mark Christopherson , Martin Gerber , Julie Woessner
IPC分类号： A61B17/00 , A61B18/14
CPC分类号： A61B18/1477 , A61B18/1485 , A61B2017/00274 , A61B2018/00547 , A61B2018/00577 , A61B2018/143 , A61B2018/1472 , A61B2018/1475
摘要： A device and method for transurethral needle ablation of prostate tissue to alleviate BPH uses bipolar ablation needles and a virtual electrode. To create the virtual electrode, a conductive fluid is delivered to the target site within the prostate tissue. Ablation energy is then delivered to the target tissue and the virtual electrode via a pair of bipolar ablation needles. The ablation energy flows between the bipolar ablation needles, throughout the virtual electrode and the prostate tissue to create ablation lesions within the prostate.
摘要翻译：用于前列腺组织经尿道针消融以减轻BPH的装置和方法使用双极消融针和虚拟电极。为了产生虚拟电极，将导电流体输送到前列腺组织内的靶位点。然后通过一对双极消融针将消融能量输送到目标组织和虚拟电极。消融能量在双极消融针之间穿过虚拟电极和前列腺组织，在前列腺内产生消融损伤。

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