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    • 2. 发明申请
    • MEDICAL INSTRUMENT AND METHOD OF USE
    • 医用仪器及其使用方法
    • US20120271300A9
    • 2012-10-25
    • US11329381
    • 2006-01-10
    • John ShadduckMichael Hoey
    • John ShadduckMichael Hoey
    • A61B18/18A61F7/12A61F7/00
    • A61B18/042A61B18/04A61B2018/00619A61B2018/0063A61B2018/046A61B2018/048
    • An instrument for thermally-mediated therapies in targeted tissue volumes or for volumetric removal of tissue. In one embodiment, the instrument has an interior chamber that includes a diffuser structure for diffusing a biocompatible conductive fluid that is introduced under high pressure. The interior chamber further includes surfaces of opposing polarity electrodes for vaporizing the small cross-section diffused fluid flows created within a diffuser structure. In one embodiment, the diffuser structure includes a negative temperature coefficient of resistance material between the opposing polarity surfaces. The NTCR structure can self-adjust the lengths of current paths between the opposing polarities to insure complete vaporization of the volume of flow of conductive fluid. The non-ionized vapor phase media is ejected from a working surface of the instrument and a controlled vapor-to-liquid phase change in an interface with tissue applies thermal energy substantially equal to the heat of vaporization to ablate tissue. In another embodiment, the instrument provides voltage means for converting the non-ionized vapor phase media into an ionized media or plasma for applying energy to body structure.
    • 用于靶向组织体积或体积去除组织的热介导疗法的仪器。 在一个实施例中,仪器具有内部腔室,其包括用于扩散在高压下引入的生物相容性导电流体的扩散器结构。 内部腔室还包括相对极性电极的表面,用于蒸发在扩散器结构内产生的小横截面扩散的流体流。 在一个实施例中,扩散器结构包括在相对的极性表面之间的电阻材料的负温度系数。 NTCR结构可以自我调节相对极性之间的电流通路的长度,以确保导电流体流量的完全蒸发。 非离子化的气相介质从仪器的工作表面喷出,并且与组织的界面中受控的蒸气 - 液相变化施加基本上等于蒸发热消融组织的热能。 在另一个实施例中,仪器提供电压装置,用于将非电离气相介质转换成离子化介质或等离子体,以将能量施加到体结构。
    • 6. 发明授权
    • Medical instruments and techniques for treating pulmonary disorders
    • 用于治疗肺部疾病的医疗仪器和技术
    • US08187269B2
    • 2012-05-29
    • US12947228
    • 2010-11-16
    • John H. ShadduckMichael Hoey
    • John H. ShadduckMichael Hoey
    • A61B18/18
    • A61B18/04A61B17/32037A61B2017/00809A61B2018/00315A61B2018/048
    • A surgical instrument for delivering energy to lung tissue, for example to cause lung volume reduction. In one embodiment, an elongated catheter has a handle portion that includes an interior chamber that is supplied with a biocompatible liquid media under pressure. An energy source delivers energy to the media to cause a liquid-to-vapor phase change within the interior chamber and ejects a flow of vapor media from the working end of the catheter. The delivery of energy and the flow of vapor are controlled by a computer controller to cause a selected pressure and selected volume of vapor to propagate to the extremities of the airways. Contemporaneously, the vapor undergoes a vapor-to-liquid phase transition which delivers large amount of energy to the airway tissue. The thermal energy delivered is equivalent to the heat of vaporization of the fluid media, which shrinks and collapses the treated airways. The treated tissue is the maintained in a collapsed state by means of aspiration for a short interval to enhance tissue remodeling. Thereafter, the patient's wound healing response causes fibrosis and further remodeling to cause permanent lung volume reduction.
    • 用于向肺组织递送能量的手术器械,例如以减少肺容积。 在一个实施例中,细长导管具有手柄部分,该手柄部分包括在压力下供应生物相容性液体介质的内部腔室。 能量源将能量传递到介质以在内部室内引起液体 - 气相变化,并从导管的工作端喷出蒸气介质流。 能量的传递和蒸气的流动由计算机控制器控制,以使所选压力和选定体积的蒸气传播到气道的末端。 同时,蒸气经历气 - 液相转移,其向气道组织输送大量的能量。 传递的热能相当于流体介质的蒸发热量,这会使经过处理的气道收缩和收缩。 经处理的组织通过抽吸短时间保持在折叠状态以增强组织重塑。 此后,患者的伤口愈合反应引起纤维化并进一步重塑以造成永久肺容积减少。
    • 9. 发明申请
    • METHOD AND APPARATUS FOR CREATING A BI-POLAR VIRTUAL ELECTRODE USED FOR THE ABLATION OF TISSUE
    • 用于创建用于组织组织的双极虚拟电极的方法和装置
    • US20080103497A1
    • 2008-05-01
    • US11966769
    • 2007-12-28
    • PETER MULIERMichael Hoey
    • PETER MULIERMichael Hoey
    • A61B18/14
    • A61B18/14A61B18/1482A61B2018/00005A61B2018/00053A61B2018/00291A61B2018/00642A61B2018/00702A61B2018/00791A61B2018/00875A61B2018/126A61B2018/1472A61B2218/002A61B2218/007
    • A method and apparatus for creating a virtual electrode to ablate bodily tissue. The apparatus includes an outer tube, a first electrode, an inner tube and a second electrode. The outer tube is fluidly connected to a source of conductive fluid and defines a proximal end and a distal end. The distal end includes an opening for delivering conductive fluid from the outer tube. The first electrode is disposed at the distal end of the outer tube for applying a current to conductive fluid delivered from the outer tube. The inner tube is coaxially received within the outer tube and is connected to a source of conductive fluid. The inner tube defines a proximal end and a distal end, with the distal end forming an opening for delivering conductive fluid from the inner tube. Finally, the second electrode is disposed at the distal end of the inner tube for applying a current to conductive fluid delivered from the inner tube. With this configuration, upon final assembly, the distal end of the outer tube is axially spaced from the distal end of the inner tube such that the first electrode is spaced from the second electrode. As a result, a bi-polar virtual electrode can be established.
    • 一种用于产生虚拟电极以消除身体组织的方法和装置。 该装置包括外管,第一电极,内管和第二电极。 外管流体地连接到导电流体源并且限定近端和远端。 远端包括用于从外管输送导电流体的开口。 第一电极设置在外管的远端,用于向从外管输送的导电流体施加电流。 内管同轴地容纳在外管内并连接到导电流体源。 内管限定近端和远端,远端形成用于从内管输送导电流体的开口。 最后,第二电极设置在内管的远端,用于向从内管传送的导电流体施加电流。 利用该构造,在最终组装时,外管的远端与内管的远端轴向间隔开,使得第一电极与第二电极间隔开。 结果,可以建立双极虚拟电极。