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    • 6. 发明申请
    • Method and apparatus for delivering oxygen and/or other gases to tissue
    • 将氧气和/或其他气体输送到组织的方法和装置
    • US20080294086A1
    • 2008-11-27
    • US12008130
    • 2008-01-09
    • Christoph HehrleinMichael BraunJohn S. GeisTodd Davenport
    • Christoph HehrleinMichael BraunJohn S. GeisTodd Davenport
    • A61M5/00A61N1/30A61M25/00
    • A61L27/56A61L29/146A61L31/146
    • A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.
    • 一种系统,包括:中空管,其具有远端,近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内,以便:(i)富气体全氟化碳溶液有效地并入多孔膜中; 和(ii)当多孔膜位于血液中时,富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来,以防止在血液中产生栓塞,同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学,血液在几分钟到几个小时之间变化。