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1. 发明申请

US20050214831A1 Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer 审中-公开
公开(公告)号：US20050214831A1
公开(公告)日：2005-09-29
申请号：US11050926
申请日：2005-02-04
申请人： John Monahan , Manjula Gannavarapu , Sebastian Hoersch , Shubhangi Kamatkar , Steven Kovats , Rachel Meyers , Michael Morrissey , Peter Olandt , Ami Sen , Petter Veiby , Gordon Mills , Robert Bast , Karen Lu , Rosemarie Schmandt , Xumei Zhao , Karen Glatt
发明人： John Monahan , Manjula Gannavarapu , Sebastian Hoersch , Shubhangi Kamatkar , Steven Kovats , Rachel Meyers , Michael Morrissey , Peter Olandt , Ami Sen , Petter Veiby , Gordon Mills , Robert Bast , Karen Lu , Rosemarie Schmandt , Xumei Zhao , Karen Glatt
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided.

2. 发明申请

US20070190550A1 Novel compositions and methods for the identification, assessment, prevention, and therapy of human cancers 审中-公开
标题翻译：用于鉴定，评估，预防和治疗人类癌症的新型组合物和方法
公开(公告)号：US20070190550A1
公开(公告)日：2007-08-16
申请号：US11634620
申请日：2006-12-06
申请人： Natalia Iartchouk , Mark Ayers , Jeffrey Brown , Robert Bast , Karen Lu , Gordon Mills
发明人： Natalia Iartchouk , Mark Ayers , Jeffrey Brown , Robert Bast , Karen Lu , Gordon Mills
IPC分类号： C12Q1/68 , G01N33/574 , C12N5/06 , C07K16/30
CPC分类号： A61K31/337 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/57449 , G01N2800/52
摘要： The present invention is directed to the identification of markers that can be used to determine whether tumors are sensitive or resistant to a therapeutic agent. The present invention is also directed to the identification of therapeutic targets. The invention features a number of “sensitivity markers.” These are markers that are expressed in most or all cell lines that are sensitive to treatment with an agent and which are not expressed (or are expressed at a rather low level) in cells that are resistant to treatment with that agent. The invention also features a number of “resistance markers.” These are markers that are expressed in most or all cell lines that are resistant to treatment with an agent and which are not expressed (or are expressed at a rather low level) in cells that are sensitive to treatment with that agent.
摘要翻译：本发明涉及可用于确定肿瘤是否对治疗剂敏感或抗性的标志物的鉴定。本发明还涉及治疗靶标的鉴定。本发明具有许多“灵敏度标记”。这些标记物在大多数或所有细胞系中表达，其对于用药物治疗敏感并且在对该药物治疗有抗性的细胞中不表达（或以相当低的水平表达）表达。本发明还具有许多“电阻标记”。这些是在大多数或所有细胞系中表达的标记，其对于用药物治疗是有抗性的，并且在对用该药物治疗敏感的细胞中不表达（或以相当低的水平表达）表达。

3. 外观设计

USD668338S1 Tool implement release collar 有权
标题翻译：工具拆装环
公开(公告)号：USD668338S1
公开(公告)日：2012-10-02
申请号：US29378934
申请日：2010-11-11
申请人： Robert Bast , Robert F. Miller
设计人： Robert Bast , Robert F. Miller

4. 外观设计

USD663025S1 Handle 有权
公开(公告)号：USD663025S1
公开(公告)日：2012-07-03
申请号：US29410178
申请日：2012-01-05
申请人： Robert Bast , Austin R. S. Braganza , Mara C. Schwartz
设计人： Robert Bast , Austin R. S. Braganza , Mara C. Schwartz

5. 外观设计

USD660421S1 Tool grip 有权
公开(公告)号：USD660421S1
公开(公告)日：2012-05-22
申请号：US29376228
申请日：2010-10-04
申请人： Robert F. Miller , Robert Bast
设计人： Robert F. Miller , Robert Bast

6. 外观设计

USD647201S1 Tool 有权
公开(公告)号：USD647201S1
公开(公告)日：2011-10-18
申请号：US29376223
申请日：2010-10-04
申请人： Michael T. Gauthier , Robert F. Miller , Robert Bast , Austin R. S. Braganza
设计人： Michael T. Gauthier , Robert F. Miller , Robert Bast , Austin R. S. Braganza

7. 发明申请

US20070089733A1 Wood-burning boiler 失效
标题翻译：燃木锅炉
公开(公告)号：US20070089733A1
公开(公告)日：2007-04-26
申请号：US11583998
申请日：2006-10-19
申请人： Robert Bast
发明人： Robert Bast
IPC分类号： F23L15/00
CPC分类号： F23B90/00 , F23B1/26 , F23B1/34 , F23B60/02 , F23B80/00 , F23L1/02 , F23L9/02 , F23L15/04 , Y02E20/348
摘要： A wood-burning boiler is provided, comprising a combustion chamber having a first air intake, and being adapted for holding combustible wood. An exhaust chamber is fluidly coupled to the combustion chamber, and is adapted to receive burnt gases from the combustion chamber. A preheat chamber is included, having a second air intake, and the preheat chamber is fluidly coupled to the combustion chamber and is conductively proximate to the exhaust chamber such that the burnt gases in the exhaust chamber heat the air within the preheat chamber prior to the air in the preheat chamber entering the combustion chamber. The boiler also includes a water jacket conductively proximate the combustion chamber.
摘要翻译：提供了一种燃木锅炉，其包括具有第一进气口的燃烧室，并且适于容纳可燃木材。排气室流体地联接到燃烧室，并且适于接收来自燃烧室的燃烧气体。包括预热室，具有第二空气入口，并且预热室流体地联接到燃烧室并且导电地靠近排气室，使得排气室内的燃烧气体在预热室之前加热预热室内的空气进入燃烧室的预热室内的空气。锅炉还包括导电接近燃烧室的水套。

8. 发明授权

US06233814B1 Method of producing an electromagnetic coil 有权
标题翻译：电磁线圈的制造方法
公开(公告)号：US06233814B1
公开(公告)日：2001-05-22
申请号：US09298023
申请日：1999-04-22
申请人： Robert Bast , Frank Rieck , Klaus-D. Wustefeld , Werner M. Leuschner , Horst Grove , Heinrich Rheinlander
发明人： Robert Bast , Frank Rieck , Klaus-D. Wustefeld , Werner M. Leuschner , Horst Grove , Heinrich Rheinlander
IPC分类号： H01F706
CPC分类号： H01R4/4818 , H01F5/04 , H01F7/06 , H01F41/10 , H01F2007/062 , Y10T29/4902 , Y10T29/49071
摘要： A method of producing an electromagnetic coil comprises winding a length of electrically conductive wire about a non-conductive tubular body having electrically conductive pins embedded therein, coupling opposite ends of the wire to the respective pins, and embedding the pins more deeply in the body following the coupling of the opposite ends of the wire to such pins.
摘要翻译：一种制造电磁线圈的方法包括：将导电线缠绕在具有嵌入其中的导电针的非导电管状体上，将导线的相对端分别连接到相应的引脚上，并将引脚更深地嵌入体内电线的相对端与这种销的耦合。

9. 发明申请

US20100068724A1 Biomaker for ovarian and endometrial cancer: hepcidin 审中-公开
标题翻译：卵巢和子宫内膜癌的生物制剂：铁调素
公开(公告)号：US20100068724A1
公开(公告)日：2010-03-18
申请号：US12381218
申请日：2009-03-09
申请人： Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song , Valdimir Podust , Zhen Zhang
发明人： Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song , Valdimir Podust , Zhen Zhang
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/6851 , G01N33/57442 , G01N33/57449 , G01N33/68 , G01N33/74 , G01N2500/00
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译：本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。特别地，已经发现，铁调素是卵巢癌和子宫内膜癌的生物标志物，并且一组生物标志物，包括铁调素，转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。生物标志物可以通过SELDI质谱检测。

10. 发明申请

US20090170208A1 Biomarkers for ovarian cancer 有权
标题翻译：卵巢癌生物标记物
公开(公告)号：US20090170208A1
公开(公告)日：2009-07-02
申请号：US12079592
申请日：2008-03-27
申请人： Eric T. Fung , Robert Bast , Vladimir Podust , Charlotte Clarke
发明人： Eric T. Fung , Robert Bast , Vladimir Podust , Charlotte Clarke
IPC分类号： G01N33/574 , G01N33/48 , G06N7/02
CPC分类号： G01N33/57449 , G01N33/5091 , G01N2800/56 , G01N2800/60
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, it has been found that the biomarkers set forth in Table 1 are biomarkers for ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译：本发明提供了可用于评估患者卵巢癌状态的基于蛋白质的生物标志物和生物标志物组合。特别地，已经发现表1中列出的生物标志物是卵巢癌的生物标志物。生物标志物可以通过SELDI质谱检测。

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