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1. 发明申请

US20100331938A1 IMPLANTABLE MEDICAL DEVICE LEAD 有权
标题翻译：可植入医疗器械引线
公开(公告)号：US20100331938A1
公开(公告)日：2010-12-30
申请号：US12825647
申请日：2010-06-29
申请人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
发明人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/0558 , A61N1/086
摘要： An implantable lead including a lead body including an outer surface, a proximal end, a distal end, and at least one electrode; an electrically insulating member that extends axially over a first portion of the outer surface of the lead body between the proximal end and distal end, the electrically insulating member defining at least one aperture that exposes a first portion of the at least one electrode when in a first position over the lead body; and a reinforcement member formed at least partially of a different material than the insulating member and coupled to the insulating member, the reinforcement member extending axially over the outer surface of the lead body between the insulating member and proximal end. The reinforcement member may be configured to transfer at least one of a radial or axial force from a proximal portion of the reinforcement member to the insulating member, wherein the at least one of radial or axial force transferred to the insulating member is sufficient to move the insulating member over the outer surface of the lead body. In some examples, the lead may further include a deployable lobe member configured to anchor the reinforcement member and insulating member adjacent a tissue site within a patient.
摘要翻译：一种可植入引线，包括：引线本体，其包括外表面，近端，远端和至少一个电极; 电绝缘构件，其在所述近端和远端之间轴向延伸到所述引线本体的外表面的第一部分上方，所述电绝缘构件限定在至少一个孔处暴露所述至少一个电极的第一部分，领先身体的第一位; 至少部分地由与所述绝缘构件不同的材料形成并且与所述绝缘构件连接的加强构件，所述加强构件在所述绝缘构件和所述绝缘构件与所述绝缘构件之间的所述引线本体的外表面上轴向延伸。加强构件可以构造成将径向或轴向力中的至少一个从加强构件的近侧部分传递到绝缘构件，其中传递到绝缘构件的径向或轴向力中的至少一个足以使绝缘构件在引线体的外表面上。在一些示例中，引线还可包括可展开的隆起部件，其构造成将加强部件和绝缘部件固定在患者体内的组织部位附近。

2. 发明授权

US08340783B2 Implantable medical device lead with selectively exposed electrodes and reinforcement member 有权
标题翻译：植入式医疗器械引线带有选择性暴露的电极和加强构件
公开(公告)号：US08340783B2
公开(公告)日：2012-12-25
申请号：US12825647
申请日：2010-06-29
申请人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
发明人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/0558 , A61N1/086
摘要： An implantable lead including a lead body including an outer surface, a proximal end, a distal end, and at least one electrode; an electrically insulating member that extends axially over a first portion of the outer surface of the lead body between the proximal end and distal end, the electrically insulating member defining at least one aperture that exposes a first portion of the at least one electrode when in a first position over the lead body; and a reinforcement member formed at least partially of a different material than the insulating member and coupled to the insulating member, the reinforcement member extending axially over the outer surface of the lead body between the insulating member and proximal end. The reinforcement member may be configured to transfer at least one of a radial or axial force from a proximal portion of the reinforcement member to the insulating member, wherein the at least one of radial or axial force transferred to the insulating member is sufficient to move the insulating member over the outer surface of the lead body. In some examples, the lead may further include a deployable lobe member configured to anchor the reinforcement member and insulating member adjacent a tissue site within a patient.
摘要翻译：一种可植入引线，包括：引线本体，其包括外表面，近端，远端和至少一个电极; 电绝缘构件，其在所述近端和远端之间轴向延伸到所述引线本体的外表面的第一部分上方，所述电绝缘构件限定在至少一个孔处暴露所述至少一个电极的第一部分，领先身体的第一位; 至少部分地由与所述绝缘构件不同的材料形成并且与所述绝缘构件连接的加强构件，所述加强构件在所述绝缘构件和所述绝缘构件与所述绝缘构件之间的所述引线本体的外表面上轴向延伸。加强构件可以构造成将径向或轴向力中的至少一个从加强构件的近侧部分传递到绝缘构件，其中传递到绝缘构件的径向或轴向力中的至少一个足以使绝缘构件在引线体的外表面上。在一些示例中，引线还可包括可展开的隆起部件，其构造成将加强部件和绝缘部件固定在患者体内的组织部位附近。

3. 发明授权

US08244339B2 Wireless cardiac pulsatility sensing 有权
标题翻译：无线心脏搏动检测
公开(公告)号：US08244339B2
公开(公告)日：2012-08-14
申请号：US12852740
申请日：2010-08-09
申请人： Xiaonan Shen , Can Cinbis
发明人： Xiaonan Shen , Can Cinbis
IPC分类号： A61B5/04
CPC分类号： A61B5/6846 , A61B5/0245 , A61B5/0538 , A61N1/3937 , A61N1/3956 , A61N1/3987
摘要： An implantable medical device system and associated method monitor changes in transimpedance in a body tissue due to changes in cardiac pulsatility. A first dipole is used to deliver a non-stimulating electrical current. The first dipole includes a first electrode and a second electrode adapted to be deployed along a first body location. A second dipole is used to measure a voltage resulting from the non-stimulating electrical current being conducted through a portion of a patient's body. The second dipole includes a third electrode and a fourth electrode different than the first electrode and the second electrode and adapted to be deployed along a second body location spaced apart from the first body location.
摘要翻译：可植入医疗装置系统和相关方法监测由于心脏搏动的变化而导致的身体组织中的跨阻抗变化。第一偶极子用于传递非刺激电流。第一偶极子包括适于沿着第一身体位置展开的第一电极和第二电极。使用第二偶极子来测量通过患者身体的一部分传导的非刺激性电流产生的电压。第二偶极子包括不同于第一电极和第二电极的第三电极和第四电极，并且适于沿着与第一主体位置间隔开的第二主体位置展开。

4. 发明授权

US09867990B2 Determination of dipole for tissue conductance communication 有权
公开(公告)号：US09867990B2
公开(公告)日：2018-01-16
申请号：US12915788
申请日：2010-10-29
申请人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
发明人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
IPC分类号： A61N1/40 , A61N1/372 , A61B5/00 , A61N1/08 , H04B13/00
CPC分类号： A61N1/37217 , A61B5/0028 , A61N1/08 , H04B13/005
摘要： Aspects of the present disclosure include a medical device system including an implantable medical device and an external device with three or more electrodes configured to contact a patient's skin. The external device either transmits or receives a test signal to or from the implantable medical device using a plurality of possible receive dipoles, where each possible receive dipole is formed by a pair of electrodes. A signal quality monitor, either at the implantable medical device or at the external device, measures a signal quality for the possible receive dipoles.

5. 发明申请

US20120035490A1 WIRELESS CARDIAC PULSATILITY SENSING 有权
标题翻译：无线心脏脉搏传感
公开(公告)号：US20120035490A1
公开(公告)日：2012-02-09
申请号：US12852740
申请日：2010-08-09
申请人： Xiaonan Shen , Can Cinbis
发明人： Xiaonan Shen , Can Cinbis
IPC分类号： A61B5/0464 , A61B5/053
CPC分类号： A61B5/6846 , A61B5/0245 , A61B5/0538 , A61N1/3937 , A61N1/3956 , A61N1/3987
摘要： An implantable medical device system and associated method monitor changes in transimpedance in a body tissue due to changes in cardiac pulsatility. A first dipole is used to deliver a non-stimulating electrical current. The first dipole includes a first electrode and a second electrode adapted to be deployed along a first body location. A second dipole is used to measure a voltage resulting from the non-stimulating electrical current being conducted through a portion of a patient's body. The second dipole includes a third electrode and a fourth electrode different than the first electrode and the second electrode and adapted to be deployed along a second body location spaced apart from the first body location.
摘要翻译：可植入医疗装置系统和相关方法监测由于心脏搏动的变化而导致的身体组织中的跨阻抗变化。第一偶极子用于传递非刺激电流。第一偶极子包括适于沿着第一身体位置展开的第一电极和第二电极。使用第二偶极子来测量通过患者身体的一部分传导的非刺激性电流产生的电压。第二偶极子包括不同于第一电极和第二电极的第三电极和第四电极，并且适于沿着与第一主体位置间隔开的第二主体位置展开。

6. 发明申请

US20100030312A1 METHOD AND APPARATUS FOR LEAD LENGTH DETERMINATION 审中-公开
标题翻译：铅长度测定方法与装置
公开(公告)号：US20100030312A1
公开(公告)日：2010-02-04
申请号：US12183592
申请日：2008-07-31
申请人： Xiaonan Shen
发明人： Xiaonan Shen
IPC分类号： A61N1/00 , A61B5/05
CPC分类号： A61B5/06 , A61B5/1076 , A61B17/3468 , A61B34/20 , A61B2034/2051 , A61B2090/061 , A61N1/0573
摘要： A method and apparatus for positioning a lead within an anatomy is disclosed. The apparatus can be tracked relative to the anatomy to determine the position of selected portions of the anatomy. The positions of the portions of the anatomy can be used in determining an appropriate lead length to be positioned within the anatomy. Additionally, a determination of a lead length can be based upon statistical or acquired data of a selected population, according to an appropriate method.
摘要翻译：公开了一种用于将铅定位在解剖结构内的方法和装置。可以相对于解剖结构跟踪装置，以确定解剖结构的所选部分的位置。解剖结构部分的位置可以用于确定要定位在解剖结构内的适当引线长度。此外，根据适当的方法，可以基于所选群体的统计或获取的数据来确定前导长度。

7. 发明授权

US08369932B2 Optical methods of identifying the location of a medical device within a patient's body in order to locate the fossa ovalis for trans-septal procedures 有权
标题翻译：识别病人体内医疗器械位置的光学方法，以定位卵巢卵巢以进行反间隔手术
公开(公告)号：US08369932B2
公开(公告)日：2013-02-05
申请号：US12696488
申请日：2010-01-29
申请人： Can Cinbis , Xiaonan Shen , Jonathan Kuhn
发明人： Can Cinbis , Xiaonan Shen , Jonathan Kuhn
IPC分类号： A61B5/00
CPC分类号： A61B5/14552 , A61B5/0044 , A61B5/0075 , A61B5/0084 , A61B5/061 , A61B5/064 , A61B5/065 , A61B5/1459 , A61B5/4887 , A61B5/6852 , A61B5/72 , A61B90/39 , A61B2017/00061 , A61B2017/00243 , A61B2090/306 , A61B2562/0242
摘要： A system and method for identifying the location of a medical device within a patient's body may be used to locate or identify the fossa ovalis for trans-septal procedures. The systems and methods measure light reflected by tissues encountered by an optical array. An optical array detects characteristic wavelengths of tissues that are different distances from the optical array. The reflectance of different wavelengths of light at different distances from an optical array may be used to identify the types of tissue encountered, including oxygenated blood in the left atrium as detected from the right atrium through the fossa ovalis.
摘要翻译：可以使用用于识别患者体内的医疗装置的位置的系统和方法来定位或识别用于反间隔程序的卵圆窝。系统和方法测量由光学阵列遇到的组织反射的光。光学阵列检测与光学阵列不同距离的组织的特征波长。可以使用与光学阵列不同距离的不同波长的光的反射率来识别遇到的组织的类型，包括从右心房通过卵圆窝检测到的左心房中的氧合血液。

8. 发明申请

US20120109258A1 DETERMINATION OF DIPOLE FOR TISSUE CONDUCTANCE COMMUNICATION 有权
标题翻译：用于组织结构通信的DIPOLE的确定
公开(公告)号：US20120109258A1
公开(公告)日：2012-05-03
申请号：US12915788
申请日：2010-10-29
申请人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
发明人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
IPC分类号： A61N1/08
CPC分类号： A61N1/37217 , A61B5/0028 , A61N1/08 , H04B13/005
摘要： Aspects of the present disclosure include a medical device system including an implantable medical device and an external device with three or more electrodes configured to contact a patient's skin. The external device either transmits or receives a test signal to or from the implantable medical device using a plurality of possible receive dipoles, where each possible receive dipole is formed by a pair of electrodes. A signal quality monitor, either at the implantable medical device or at the external device, measures a signal quality for the possible receive dipoles.
摘要翻译：本公开的方面包括包括可植入医疗装置的医疗装置系统和具有被配置为接触患者皮肤的三个或更多个电极的外部装置。外部设备使用多个可能的接收偶极子向可植入医疗设备发送测试信号或从可植入医疗设备接收测试信号，其中每个可能的接收偶极由一对电极形成。在可植入医疗设备或外部设备处的信号质量监视器测量可能的接收偶极子的信号质量。

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