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    • 2. 发明申请
    • Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
    • 用于检测核四极和核磁共振信号的Q因子切换方法和装置
    • US20070040556A1
    • 2007-02-22
    • US11438439
    • 2006-05-23
    • Taras RudakovVassili MikhaltsevitchWarrick ChisholmJohn FlexmanPeter Hayes
    • Taras RudakovVassili MikhaltsevitchWarrick ChisholmJohn FlexmanPeter Hayes
    • G01V3/00
    • G01R33/441G01R33/3628G01V3/14
    • A probe (80) for irradiating a sample with RF energy during transmitting periods and detecting an NQR or NMR signal from a substance contained within the sample during receiving periods. The probe (80) comprises a variable impedance unit (20) for changing the Q-factor of the probe and a probe coil. The probe (80) is responsive to powerful RF pulses applied thereto to excite an RF magnetic field in the probe coil during the transmitting periods. The variable impedance unit (20) is controllable to provide a Q-factor for the probe (80) at: (i) an optimal level during a prescribed transmitting period of an RF pulse for irradiating the sample with said RF energy; (ii) a minimal level during a prescribed recovery period immediately following said transmitting period to rapidly dampen transient signals from the probe; and (iii) a maximal level during a prescribed receiving period for detecting an NQR or NMR signal from the target substance if present, immediately following the recovery period. A method for detecting an NQR or NMR signal within a sample using the probe (80) is also described.
    • 用于在发射期间用RF能量照射样品的探针(80),并且在接收期间从包含在样品中的物质检测NQR或NMR信号。 探针(80)包括用于改变探针的Q因子和探针线圈的可变阻抗单元(20)。 探针(80)响应于施加到其上的强大的RF脉冲,以在发射期间激发探针线圈中的RF磁场。 可变阻抗单元(20)是可控制的,以便在以下条件下为探针(80)提供Q因子:(i)在用于用所述RF能量照射样本的RF脉冲的规定的发射周期期间的最佳电平; (ii)紧接在所述传输周期之后的规定的恢复期间的最小电平以快速抑制来自探针的瞬态信号; 以及(iii)在规定的接收期间内,在恢复期之后立即检测来自目标物质(如果存在)的NQR或NMR信号的最大电平。 还描述了使用探针(80)检测样品内的NQR或NMR信号的方法。
    • 4. 发明申请
    • Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
    • 用于检测核四极和核磁共振信号的Q因子切换方法和装置
    • US20050116714A1
    • 2005-06-02
    • US10838256
    • 2004-05-05
    • Taras RudakovVassili MikhaltsevitchWarrick ChisholmJohn FlexmanPeter Hayes
    • Taras RudakovVassili MikhaltsevitchWarrick ChisholmJohn FlexmanPeter Hayes
    • G01R33/36G01R33/44G01V3/14G01V3/00
    • G01R33/441G01R33/3628G01V3/14
    • A probe (80) for irradiating a sample with RF energy during transmitting periods and detecting an NQR or NMR signal from a substance contained within the sample during receiving periods. The probe (80) comprises a variable impedance unit (20) for changing the Q-factor of the probe and a probe coil. The probe (80) is responsive to powerful RF pulses applied thereto to excite an RF magnetic field in the probe coil during the transmitting periods. The variable impedance unit (20) is controllable to provide a Q-factor for the probe (80) at: (i) an optimal level during a prescribed transmitting period of an RF pulse for irradiating the sample with said RF energy; (ii) a minimal level during a prescribed recovery period immediately following said transmitting period to rapidly dampen transient signals from the probe; and (iii) a maximal level during a prescribed receiving period for detecting an NQR or NMR signal from the target substance if present, immediately following the recovery period. A method for detecting an NQR or NMR signal within a sample using the probe (80) is also described.
    • 用于在发射期间用RF能量照射样品的探针(80),并且在接收期间从包含在样品中的物质检测NQR或NMR信号。 探针(80)包括用于改变探针的Q因子和探针线圈的可变阻抗单元(20)。 探针(80)响应于施加到其上的强大的RF脉冲,以在发射期间激发探针线圈中的RF磁场。 可变阻抗单元(20)是可控制的,以便在以下条件下为探针(80)提供Q因子:(i)在用于用所述RF能量照射样本的RF脉冲的规定发射周期期间的最佳电平; (ii)紧接在所述传输周期之后的规定的恢复期间的最小电平以快速抑制来自探针的瞬态信号; 以及(iii)在规定的接收期间内,在恢复期之后立即检测来自目标物质(如果存在)的NQR或NMR信号的最大电平。 还描述了使用探针(80)检测样品内的NQR或NMR信号的方法。
    • 6. 发明申请
    • Pulse sequences for exciting nuclear quadrupole resonance
    • 用于激发核四极共振的脉冲序列
    • US20060091883A1
    • 2006-05-04
    • US10518480
    • 2003-06-20
    • Vassili MikhaltsevitchTaras RudakovJohn FlexmanPeter HayesWarrick Chisholm
    • Vassili MikhaltsevitchTaras RudakovJohn FlexmanPeter HayesWarrick Chisholm
    • G01V3/00
    • G01R33/441G01N24/084G01R33/5613
    • An apparatus and a method for producing a multi-pulse sequence for irradiating a substance provided with quadrupole nuclei with either integer or half-integer spins to detect an NQR signal emitted therefrom. The apparatus has pulse sequence generating means adapted to produce a combination of two or more pulse sequences, arranged so that a definite regularity of the phase alteration of pulses in each of the pulse sequences occurs that is equivalent to a shift of spectral components of the pulse sequences in relation to each other. Furthermore, in at least one of the pulse sequences, there are not less than two phases alternating. A preparatory pulse may be included in one of the pulse sequences to reduce the effect of temperature, increase the intensity of the NQR signal and simultaneously eliminate intensity anomalies. Alternatively, the combination of pulse sequences may be different from a combination of PAPS and NPAPS, and none of the pulse sequences contain a preparatory pulse.
    • 一种用于产生用于向具有四极核的物质照射具有整数或半整数自旋的物质的多脉冲序列的装置和方法,以检测从其发射的NQR信号。 该装置具有适于产生两个或多个脉冲序列的组合的脉冲序列发生装置,其被布置为使得发生每个脉冲序列中的脉冲相位变化的确定规律,其相当于脉冲的频谱分量的偏移 相互关联的序列。 此外,在至少一个脉冲序列中,存在不少于两相的交替。 预备脉冲可以包括在脉冲序列之一中以减少温度的影响,增加NQR信号的强度并同时消除强度异常。 或者,脉冲序列的组合可以不同于PAPS和NPAPS的组合,并且脉冲序列都不包含预备脉冲。
    • 10. 发明申请
    • Receive system for high q antennas in nqr and a method of detecting substances
    • nqr中高q天线的接收系统和物质检测方法
    • US20060033499A1
    • 2006-02-16
    • US10517627
    • 2003-06-13
    • John FlexmanPeter HayesWarick ChisholmVassile MikhaltsevitchTaras Rudakov
    • John FlexmanPeter HayesWarick ChisholmVassile MikhaltsevitchTaras Rudakov
    • G01V3/00
    • G01R33/3621G01R33/3628G01R33/441
    • A receiving system (11) for connection to an antenna arrangement (19) for detecting response signals from a substance having quadrupolar nuclei excited so as to produce nuclear quadrupole resonance in certain of the quadrupolar nuclei. A method for receiving a response signal via the antennae arrangement (19) is also described. The receiving system (11) includes an amplifier (17) to amplify the received response signal from the antenna arrangement (19) for subsequent processing, a matching section (15) to match the amplifier (17) to the antenna (19), and an isolating switch (13) to isolate the antenna from the receiving system (11). The matching section (15) noise matches the receiving system (11) to the antenna (19) during a receiving period to reduce the Q factor of the antenna without significantly degrading the signal to noise ratio. The isolating switch (13) isolates the receiving system (11) from the antenna (19) during a transmitting period when an excitation signal is transmitted by the antenna (19) to irradiate the substance. It also electrically connects the receiving system (11) to the antenna during the receiving period immediately after the transmitting period.
    • 一种用于连接到天线装置(19)的接收系统(11),用于检测来自具有四极核激励的物质的响应信号,从而在某些四极核中产生核四极共振。 还描述了一种通过天线装置(19)接收响应信号的方法。 接收系统(11)包括放大器(17),用于放大来自天线装置(19)的后续处理的接收到的响应信号,将放大器(17)与天线(19)匹配的匹配部分(15),以及 隔离开关(13),用于将天线与接收系统(11)隔离开来。 在接收周期期间,匹配部分(15)噪声与接收系统(11)匹配到天线(19),以减少天线的Q因子而不会显着降低信噪比。 隔离开关(13)在通过天线(19)发射激励信号以照射物质的发射期间隔离接收系统(11)与天线(19)。 它也在发送周期之后的接收周期期间将接收系统(11)电连接到天线。