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    • 2. 发明申请
    • Non-Invasive In-Situ Detection Of Malignant Skin Tissue And Other Abnormalities Using Laser Plasma Spectroscopy
    • 使用激光等离子体光谱法对恶性皮肤组织和其他异常的非侵入性原位检测
    • US20080269618A1
    • 2008-10-30
    • US12110528
    • 2008-04-28
    • Michael J. MyersJohn D. MyersJeffrey A. MyersAbbey G. Myers
    • Michael J. MyersJohn D. MyersJeffrey A. MyersAbbey G. Myers
    • A61B6/00A61B10/02
    • A61B5/0062A61B5/0075A61B5/444
    • Disclosed is a system and method for a non-invasive method for determining the presence or absence of cancerous cells in the skin and deeper tissue levels. The system includes a portable handheld laser coupled with a spectroscopy system to produce real-time material analysis of the presence of cancerous cells without sample preparation. The system focuses a high peak power laser pulse onto a targeted material to produce a laser spark or micro-plasma. Elemental line spectra emission is created, collected and analyzed by a spectrophotometer. The line spectra emission data is quickly displayed on a laptop computer. “Eye-safe” Class I lasers provide for practical in-situ laser plasma spectroscopy applications such as detection of cancerous skin tissues. The emission data can be used to detect changes in the levels of a series of elements that are associated with cancerous cells versus normal skin cells. The system also finds use during excisional biopsy procedures to ensure that all cancerous cells have been removed.
    • 公开了用于确定皮肤和深层组织水平中癌细胞存在或不存在的非侵入性方法的系统和方法。 该系统包括与光谱系统耦合的便携式手持式激光器,以在没有样品制备的情况下产生癌细胞的存在的实时材料分析。 该系统将高峰值功率激光脉冲聚焦到目标材料上以产生激光火花或微等离子体。 通过分光光度计产生,收集和分析元素线谱发射。 线谱发射数据快速显示在笔记本电脑上。 “眼睛安全”I类激光器提供实际的原位激光等离子体光谱应用,例如检测癌性皮肤组织。 发射数据可用于检测与癌细胞相对于正常皮肤细胞相关的一系列元件的水平的变化。 该系统还可以在切除活检过程中使用,以确保所有的癌细胞已被去除。
    • 3. 发明授权
    • Fiber laser with cladding-to-core energy migration
    • 具有包层到核心能量迁移的光纤激光器
    • US07042915B2
    • 2006-05-09
    • US10433024
    • 2001-12-07
    • John D. MyersMichael J. Myers
    • John D. MyersMichael J. Myers
    • H01S3/30
    • H01S3/06708H01S3/067H01S3/06716H01S3/1698
    • A method of transferring energy in an optical fiber (12) from the fiber's cladding element (16) of the fiber's core element (14) is disclosed. The core element (14) includes an active gain component and an energy migration component, and the cladding element (16), which surrounds the core element (14), includes the energy migration component. The method includes the steps of providing a pump (22) for producting energy and optically coupling the pump with the cladding element (16), such that the energy is absorbed and stored in the cladding element (16) by its energy migration component. A further step includes the active gain component in the core element (14) lasing or providing gain, when the transferring of energy from the cladding element's energy migration component to the core element's energy migration component takes place.
    • 公开了一种从光纤的芯元件(14)的光纤包层元件(16)向光纤(12)传输能量的方法。 核心元件(14)包括有源增益分量和能量迁移组件,并且围绕核心元件(14)的包层元件(16)包括能量迁移组件。 该方法包括以下步骤:提供用于产生能量并将泵与包层元件(16)光学耦合的泵(22),使得能量通过其能量迁移部件被吸收并存储在包层元件(16)中。 当能量从包层元件的能量迁移组件转移到核心元件的能量迁移组件时,另一步骤包括激励或提供增益的核心元件(14)中的有源增益分量。
    • 4. 发明授权
    • Optical fiber laser structure and system based on ASE pumping of cladding element
    • 光纤激光器结构和基于ASE泵浦包层元件的系统
    • US06693924B2
    • 2004-02-17
    • US10070036
    • 2002-06-07
    • John D. MyersMichael J. Myers
    • John D. MyersMichael J. Myers
    • H01S330
    • H01S3/06716H01S3/06708H01S3/06729H01S3/06737H01S3/094007H01S3/094023H01S3/1608H01S3/1611H01S3/1618H01S2301/02H01S2302/00
    • An optical fiber laser structure and system are disclosed. The fiber laser structure includes a core, an inner cladding, and an outer cladding. The core has a first and second end and includes a combination of ytterbium and erbium as a first active gain component. The inner cladding, having a length defined between the first and second ends, surrounds the core. The inner cladding includes neodymium as a second active gain component that is different from the first active gain component. The system includes a pumping source coupled to the inner cladding to provide energy to the neodymium in the inner cladding. Upon being pumped, the neodymium achieves amplified spontaneous emission in the inner cladding along the length between the first and second ends. As a result, energy is efficiently transferred from the neodymium to the combination of the ytterbium and erbium in the core thereby providing laser activity at an eye-safe laser wavelength of 1535 nanometers.
    • 公开了一种光纤激光器结构和系统。 光纤激光器结构包括芯,内包层和外包层。 芯具有第一和第二端,并且包括镱和铒的组合作为第一有源增益分量。 具有限定在第一和第二端之间的长度的内包层围绕芯。 内包层包括钕作为与第一有源增益分量不同的第二有源增益分量。 该系统包括耦合到内包层的泵浦源,以向内包层中的钕提供能量。 在被泵送时,钕在内包层中沿着第一和第二端之间的长度实现放大的自发发射。 结果,能量被有效地从钕转移到核心中的镱和铒的组合中,从而在1535纳米的眼睛安全的激光波长下提供激光活性。
    • 5. 发明授权
    • Method of transferring energy in an optical fiber laser structure using energy migration
    • 使用能量迁移在光纤激光器结构中传输能量的方法
    • US06931032B2
    • 2005-08-16
    • US10398150
    • 2001-12-07
    • John D. MyersMichael J. Myers
    • John D. MyersMichael J. Myers
    • H01S3/067H01S3/094H01S3/16H01S3/30
    • H01S3/06708H01S3/06729H01S3/06737H01S3/094003H01S3/094007H01S3/1608H01S3/1618H01S3/164H01S3/1698
    • A method of transferring energy in an optical fiber structure is disclosed. This method transfers energy from a cladding element of the fiber structure to a core element of the fiber structure. The core element includes an active gain component and an energy migration component. The cladding element, which surrounds the core element, includes the energy migration component. The structure and method can be utilized to provide either an optical fiber laser or an optical fiber amplifier. The method includes the steps of providing a pump for producing the energy and optically coupling the pump with the cladding element. The cladding element, including the energy migration component, is then pumped with the energy produced by the pump such that the energy is absorbed and stored in the cladding element by the energy migration component. The method further includes the step of transferring the energy stored in the cladding element to the core element by migration of the energy within the energy migration component to the active gain component such that the active gain component in the core element lases or provides gain.
    • 公开了一种在光纤结构中传送能量的方法。 该方法将能量从纤维结构的包层元件传递到纤维结构的芯元件。 核心元件包括主动增益组件和能量迁移组件。 围绕核心元件的包层元件包括能量迁移组件。 该结构和方法可用于提供光纤激光器或光纤放大器。 该方法包括提供用于产生能量并将泵与包层元件光学耦合的泵的步骤。 包括能量迁移组分的包层元件然后用泵产生的能量泵送,使得能量被能量迁移组分吸收并存储在包层元件中。 该方法还包括通过将能量偏移分量内的能量迁移到有源增益分量来将存储在包层元件中的能量转移到核心元件的步骤,使得核心元件中的主动增益分量变化或提供增益。
    • 7. 发明授权
    • Ytterbium-phosphate glass
    • 磷酸镱玻璃
    • US07531473B2
    • 2009-05-12
    • US11209603
    • 2005-08-23
    • John D. Myers
    • John D. Myers
    • C03C3/16C03C3/19C03C3/17
    • C03C3/16C03C3/17C03C3/19C03C4/0071H01S3/1618H01S3/175
    • A new ytterbium-phosphate glass and a method for producing the same are disclosed. The glass finds special use in forming laser glass. Previously the level of ytterbium that could be incorporated into a phosphate glass without leading to formation of crystals or devitrification was limited. It has been found that much higher levels of ytterbium can be incorporated if an initial glass melt is formed from phosphate and ytterbium prior to adding the other components. Using the present process ytterbium-phosphate glasses having up to 30 mole percent ytterbium can be created. The new glasses function as well and often better than previous ytterbium containing glasses as laser glasses especially when combined with one or more of the lasing ions erbium oxide, neodymium oxide, holmium oxide or thulium oxide.
    • 公开了一种新的磷酸镱玻璃及其制造方法。 该玻璃特别用于形成激光玻璃。 以前可以掺入磷酸盐玻璃而不导致晶体形成或失透的镱的含量受到限制。 已经发现,如果在添加其它组分之前由磷酸盐和镱形成初始玻璃熔体,则可以引入更高水平的镱。 使用本发明方法可以产生具有高达30%(摩尔)镱的镱 - 磷酸盐玻璃。 新眼镜的功能也比以前的含镱玻璃作为激光眼镜更好,特别是当与一种或多种激光离子铒氧化物,氧化钕,氧化钬或氧化when组合时。
    • 8. 发明授权
    • System for optimal electronic debugging and verification employing
scheduled cutover of alternative logic simulations
    • 用于优化电子调试和验证的系统,采用替代逻辑模拟的预定切换
    • US5566097A
    • 1996-10-15
    • US27016
    • 1993-03-05
    • John D. MyersJose L. Rivero
    • John D. MyersJose L. Rivero
    • G06F17/50G06F19/00
    • G06F17/5022
    • A system for determining the optimal circuit design simulator schedule for debugging a digital electronic circuit design. The system characterizes all available circuit design simulators in terms of several parameters reflecting simulator speed and the time required to discover, isolate and fix a design error (bug). A cutover point is established for any pair of available simulators on the basis of these parameters. One simulator is progressively more efficient than the other beyond this cutover point, which is the desired time for scheduling substitution of the more efficient simulator during the debugging process. The system also permits "what-if" evaluation of alternative debugging strategies in advance by creating alternative schedules in response to various characteristic parameters.
    • 一种用于确定用于调试数字电子电路设计的最佳电路设计模拟器计划的系统。 该系统根据反映模拟器速度和发现,隔离和修复设计错误(错误)所需的时间的几个参数来表征所有可用的电路设计模拟器。 基于这些参数为任何一对可用的模拟器建立切换点。 一个模拟器比该切换点之外的其他模拟器更有效率,这是在调试过程期间调度替代更高效模拟器的期望时间。 该系统还通过根据各种特征参数创建替代计划来提前提供替代调试策略的“假设”评估。
    • 10. 发明授权
    • Athermal laser glass composition
    • 激光玻璃组合物
    • US4333848A
    • 1982-06-08
    • US212396
    • 1980-12-03
    • John D. MyersCharles S. Vollers
    • John D. MyersCharles S. Vollers
    • C03C3/17C03C4/00C03C3/04C03C3/16C09K11/42
    • C03C4/0071C03C3/17
    • A phosphate laser glass in which the optical path length is substantially independent of temperature, or "athermal", particularly under rapid pulsing, and chemically stable, while providing high gain. The base glass composition comprises, in mole percent, 55 to 70% P.sub.2 O.sub.5, 3 to 15% of an alkali metal oxide, preferably Li.sub.2 O plus K.sub.2 O, 20 to 30% BaO and 0.5 to 5% Al.sub.2 O.sub.3. Up to 15% of the BaO may be replaced by CaO, SrO or MgO and part of the Al.sub.2 O.sub.3 may be replaced by Nd.sub.2 O.sub.3. The total Al.sub.2 O.sub.3 plus Nd.sub.2 O.sub.3 is 4 mole percent .+-.1.5%. The laser glass composition also includes a laseable component, preferably Nd.sub.2 O.sub.3 and preferably includes a solarization inhibitor.
    • 一种磷酸盐激光玻璃,其中光路长度基本上与温度无关,或“无热”,特别是在快速脉冲下,并具有化学稳定性,同时提供高增益。 基础玻璃组合物以摩尔%计含有55-70%P 2 O 5,3-15%碱金属氧化物,优选Li 2 O加K 2 O,20-30%BaO和0.5-5%Al 2 O 3。 高达15%的BaO可被CaO,SrO或MgO代替,部分Al2O3可被Nd2O3替代。 总Al2O3加Nd2O3为4摩尔%+/- 1.5%。 激光玻璃组合物还包括可发射组分,优选为Nd 2 O 3,并且优选包含防晒剂。