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1. 发明授权

US08486062B2 Curved ablation catheter 有权
标题翻译：弯曲消融导管
公开(公告)号：US08486062B2
公开(公告)日：2013-07-16
申请号：US11550302
申请日：2006-10-17
申请人： Kedar Ravindra Belhe , Saurav Paul , Hong Cao , John Avi Roop
发明人： Kedar Ravindra Belhe , Saurav Paul , Hong Cao , John Avi Roop
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00351 , A61B2018/143 , A61B2018/1475 , A61B2018/1497
摘要： A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.
摘要翻译：弯曲的消融导管向靶组织提供消融能量，例如沿着小梁斜面，例如沿着下腔静脉的口和三尖瓣之间的峡谷的右心房。导管形成有预设曲率，当展开时，两者均线性地平移并且半径增加以帮助形成斑点或连续的线性损伤。治疗心房扑动的方法采用弯曲消融导管。

2. 发明授权

US07311704B2 Spring-tip, flexible electrode catheter for tissue ablation 有权
标题翻译：弹簧尖端，柔性电极导管用于组织消融
公开(公告)号：US07311704B2
公开(公告)日：2007-12-25
申请号：US10856904
申请日：2004-05-27
申请人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , John Avi Roop , Chou Thao
发明人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , John Avi Roop , Chou Thao
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/143 , A61B2018/1435
摘要： A spring-tip, flexible electrode, and a method for using that electrode for tissue ablation, are disclosed. The spring-tip, flexible electrode comprises an enshrouded flexible electrode (e.g., an enshrouded plurality of flexible brush filaments or bristles) for applying ablative energy (e.g., RF energy) to target tissue during the formation of spot or continuous linear lesions. The spring of the spring tip may comprise compressible coils, compressible mesh, or compressible bellows, among other things. The spring provides axial suspension and is capable of axial compression and extension, and is flexible enough for deflection and bending. The axial suspension of the spring tip facilitates the desired contact between the electrode and the tissue surface. A shielded, spring-tip, flexible electrode is also disclosed, and includes a flexible nipple or shield. The spring-tip, flexible electrode facilitates enhanced tissue contact in difficult environments (e.g., during ablation of a contoured or trabeculated surface inside a beating heart) since the flexible electrode readily conforms to surface contours while the bending stress of the spring enhances the contract pressure on the tissue.
摘要翻译：公开了一种弹簧尖端，柔性电极和用于组织消融使用该电极的方法。弹簧尖端的柔性电极包括用于在形成斑点或连续的线性损伤期间向目标组织施加消融能量（例如，RF能量）的带有屏蔽的柔性电极（例如，被包围的多个柔性刷丝或刷毛）。弹簧尖端的弹簧可以包括可压缩线圈，可压缩网或可压缩波纹管等等。弹簧提供轴向悬挂并且能够轴向压缩和伸展，并且具有足够的挠性和弯曲性。弹簧顶端的轴向悬挂有助于电极和组织表面之间的所需接触。还公开了屏蔽的弹簧尖端柔性电极，并且包括柔性接头或屏蔽。弹簧尖端的柔性电极有助于在困难的环境中（例如在跳动心脏内的轮廓或小梁表面的消融期间）增强组织接触，因为柔性电极容易符合表面轮廓，同时弹簧的弯曲应力增加了收缩压力在纸巾上。

3. 发明授权

US07331959B2 Catheter electrode and rail system for cardiac ablation 有权
标题翻译：导管电极和轨道系统用于心脏消融
公开(公告)号：US07331959B2
公开(公告)日：2008-02-19
申请号：US10857421
申请日：2004-05-27
申请人： Hong Cao , John Avi Roop , Kedar Ravindra Belhe , Saurav Paul
发明人： Hong Cao , John Avi Roop , Kedar Ravindra Belhe , Saurav Paul
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00867 , A61B2018/00351 , A61B2018/143 , C08L2201/12
摘要： The instant invention is directed toward an ablation catheter and sheath incorporating wire rail system. The catheter may have a combination of rigid and flexible components to orient an ablation electrode at the distal tip toward the target tissue. The wire rail acts to guide an ablation tip along the tissue to aid in the formation of spot or continuous linear lesions on a trabecular surface, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve.
摘要翻译：本发明涉及一种包含线轨系统的消融导管和护套。导管可以具有刚性和柔性部件的组合，以将远端处的消融电极朝向靶组织定向。线轨用于沿着组织引导消融尖端以帮助在小梁表面上形成斑点或连续的线性损伤，例如沿着下腔静脉的口和三尖瓣之间的峡部的右心房。

4. 发明授权

US07276064B2 Side-port sheath for catheter placement and translation 失效
标题翻译：用于导管放置和翻译的侧端口护套
公开(公告)号：US07276064B2
公开(公告)日：2007-10-02
申请号：US10856145
申请日：2004-05-27
申请人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , John Avi Roop , Chou Thao
发明人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , John Avi Roop , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/042 , A61B2018/143 , A61B2018/1475 , A61B2018/1497
摘要： Side-port sheaths for catheter placement and translation are disclosed. The sheaths include a side-port opening through which a gliding catheter may be deployed during diagnosis or treatment of tissue. The side-port sheath may include a suspension ribbon used to deploy, or that aids in the deployment of, the embedded gliding catheter. The suspension ribbon may be slideably or fixably engaged with an outer surface of the sheath of the gliding catheter.
摘要翻译：公开了用于导管放置和平移的侧端口护套。护套包括侧口开口，在组织的诊断或处理期间可以通过滑动导管展开滑动导管。侧端口护套可以包括用于部署或有助于部署嵌入式滑翔导管的悬挂带。悬挂带可以与滑动导管的护套的外表面可滑动地或可固定地接合。

5. 发明授权

US07250049B2 Ablation catheter with suspension system incorporating rigid and flexible components 失效
标题翻译：消融导管与悬挂系统结合刚性和柔性组件
公开(公告)号：US07250049B2
公开(公告)日：2007-07-31
申请号：US10856544
申请日：2004-05-27
申请人： John Avi Roop , Kedar Ravindra Belhe , Hong Cao , Saurav Paul
发明人： John Avi Roop , Kedar Ravindra Belhe , Hong Cao , Saurav Paul
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00867 , A61B2018/00351 , A61B2018/143 , C08L2201/12
摘要： A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.
摘要翻译：弯曲的消融导管向靶组织提供消融能量，例如沿着小梁斜面，例如沿着下腔静脉的口和三尖瓣之间的峡谷的右心房。导管形成有预设曲率，当展开时，两者均线性地平移并且半径增加以帮助形成斑点或连续的线性损伤。治疗心房扑动的方法采用弯曲消融导管。

6. 发明授权

US07122034B2 Curved ablation catheter 有权
公开(公告)号：US07122034B2
公开(公告)日：2006-10-17
申请号：US10856543
申请日：2004-05-27
申请人： Kedar Ravindra Belhe , Saurav Paul , Hong Cao , John Avi Roop
发明人： Kedar Ravindra Belhe , Saurav Paul , Hong Cao , John Avi Roop
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00351 , A61B2018/143 , A61B2018/1475 , A61B2018/1497
摘要： A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.

7. 发明授权

US09283026B2 Assessment of electrode coupling for tissue ablation 有权
标题翻译：组织消融电极耦合评估
公开(公告)号：US09283026B2
公开(公告)日：2016-03-15
申请号：US12096070
申请日：2006-12-06
申请人： Saurav Paul , Hong Cao , Kedar Ravindra Belhe
发明人： Saurav Paul , Hong Cao , Kedar Ravindra Belhe
IPC分类号： A61B18/04 , A61B5/053 , A61B18/12 , A61B18/14 , A61B19/00 , A61B18/00
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter (14) and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter (14) comprises an electrode (20) adapted to apply electrical energy. A measurement circuit (42) is adapted to measure impedance between the electrode (20) and ground as the electrode approaches a target tissue (24). A processor (50) determines a contact and coupling condition for the target tissue (24) based at least in part on reactance of the impedance measured by the measurement circuit (42). In another exemplary embodiment, the electrode catheter (14) determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要翻译：公开了一种电极导管（14）和用于评估电极组织接触和耦合的方法。示例性电极导管（14）包括适于施加电能的电极（20）。测量电路（42）适于在电极接近目标组织（24）时测量电极（20）和地面之间的阻抗。处理器（50）至少部分地基于由测量电路（42）测量的阻抗的电抗来确定目标组织（24）的接触和耦合条件。在另一示例性实施例中，电极导管（14）至少部分地基于阻抗的相位角来确定接触和耦合条件。

8. 发明授权

US09283025B2 Assessment of electrode coupling for tissue ablation 有权
公开(公告)号：US09283025B2
公开(公告)日：2016-03-15
申请号：US12095701
申请日：2006-12-06
申请人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , Chou Thao
发明人： Saurav Paul , Kedar Ravindra Belhe , Hong Cao , Chou Thao
IPC分类号： A61B18/12 , A61B18/14 , A61B19/00 , A61B18/00
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.

9. 发明授权

US08449537B2 Ablation catheter with thermally mediated catheter body for mitigating blood coagulation and creating larger lesion 有权
标题翻译：消融导管与热介导的导管体减轻血液凝固和创造更大的病变
公开(公告)号：US08449537B2
公开(公告)日：2013-05-28
申请号：US11618692
申请日：2006-12-29
申请人： Hong Cao , Xiaoping Guo , Isaac Shai , Michael Yang , Kedar Ravindra Belhe , Saurav Paul , Chou Thao
发明人： Hong Cao , Xiaoping Guo , Isaac Shai , Michael Yang , Kedar Ravindra Belhe , Saurav Paul , Chou Thao
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00005 , A61B2018/00357
摘要： An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
摘要翻译：提供消融导管以消融患者的内部组织。该导管包括适于相对于其中的期望位置（例如，在心脏内）插入体腔内的远端。消融电极相对于导管的远端连接，以向患者组织提供消融能量。提供与消融电极热接触的散热器。除了与消融电极热接触之外，散热器与消融电极电隔离。这允许散热器将热量从消融电极导出，而不会从电极中消耗电能。在这方面，散热器可以防止在电极内积聚多余的热量，从而导致血液凝固和/或组织烧焦。

10. 发明申请

US20120323237A1 ASSESSMENT OF ELECTRODE COUPLING FOR TISSUE ABLATION 有权
标题翻译：电器联合电击组织评估
公开(公告)号：US20120323237A1
公开(公告)日：2012-12-20
申请号：US13593676
申请日：2012-08-24
申请人： Saurav Paul , Hong Cao , Kedar Ravindra Belhe , Chou Thao
发明人： Saurav Paul , Hong Cao , Kedar Ravindra Belhe , Chou Thao
IPC分类号： A61B18/14
CPC分类号： A61B18/1206 , A61B5/0538 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2018/00732 , A61B2018/00869 , A61B2018/00875 , A61B2018/124 , A61B2018/128
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要翻译：公开了电极导管和用于评估电极组织接触和耦合的方法。示例性电极导管包括适于施加电能的电极。测量电路适于在电极接近目标组织时测量电极和地面之间的阻抗。处理器至少部分地基于由测量电路测量的阻抗的电抗来确定目标组织的接触和耦合条件。在另一示例性实施例中，电极导管至少部分地基于阻抗的相位角确定接触和耦合条件。

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