专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08500787B2 Radiopaque markers and medical devices comprising binary alloys of titanium 失效
公开(公告)号：US08500787B2
公开(公告)日：2013-08-06
申请号：US12153254
申请日：2008-05-15
申请人： John A. Simpson , John F. Boylan , Wayne E. Cornish
发明人： John A. Simpson , John F. Boylan , Wayne E. Cornish
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2250/0098
摘要： There is disclosed medical devices, such as stents, guidewires and embolic filters, comprising a binary alloy of titanium and one binary element selected from platinum, palladium, rhodium, and gold. There is also disclosed a radiopaque marker comprising the disclosed binary alloy, as well as medical devices having the radiopaque marker attached thereto. Methods of attaching the radiopaque marker to the medical devices, such as by welding, are also disclosure also disclosed.

2. 发明授权

US07942892B2 Radiopaque nitinol embolic protection frame 有权
标题翻译：不透射线的镍钛诺栓塞保护框架
公开(公告)号：US07942892B2
公开(公告)日：2011-05-17
申请号：US10427576
申请日：2003-05-01
申请人： Peter D'Aquanni , John F. Boylan , Wayne E. Cornish
发明人： Peter D'Aquanni , John F. Boylan , Wayne E. Cornish
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/008 , A61L31/18
摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body lumen. The expandable frame also includes a filtering element. A nickel-titanium alloy is used to form the frame. Due to limited heat treatment, the frame exhibits linear pseudoelasticity when positioned inside the body lumen. The nickel-titanium alloy includes a ternary element such as iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, or hafnium so that the frame is also radiopaque.
摘要翻译：用于栓塞过滤装置的可扩展框架，用于捕获体腔内的栓塞碎片。可扩展框架还包括过滤元件。使用镍钛合金来形成框架。由于热处理有限，当定位在体腔内时，框架呈现线性假弹性。镍 - 钛合金包括三元元素如铱，铂，金，铼，钨，钯，铑，钽，银，钌或铪，使得该框架也不透射线。

3. 发明申请

US20090099645A1 Radiopaque markers and medical devices comprising binary alloys of titanium 失效
标题翻译：不透射线标记物和包含钛二元合金的医疗器械
公开(公告)号：US20090099645A1
公开(公告)日：2009-04-16
申请号：US12153254
申请日：2008-05-15
申请人： John A. Simpson , John F. Boylan , Wayne Cornish
发明人： John A. Simpson , John F. Boylan , Wayne Cornish
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2250/0098
摘要： There is disclosed medical devices, such as stents, guidewires and embolic filters, comprising a binary alloy of titanium and one binary element selected from platinum, palladium, rhodium, and gold. There is also disclosed a radiopaque marker comprising the disclosed binary alloy, as well as medical devices having the radiopaque marker attached thereto. Methods of attaching the radiopaque marker to the medical devices, such as by welding, are also disclosure also disclosed.
摘要翻译：公开了包括钛的二元合金和选自铂，钯，铑和金的一种二元元素的医疗装置，例如支架，导丝和栓塞过滤器。还公开了一种包括所公开的二元合金的不透射线标记，以及具有附着于其上的不透射线标记的医疗装置。另外还公开了将不透射线标记物附接到医疗装置的方法，例如通过焊接。

4. 发明申请

US20080288056A1 RADIOPAQUE MARKERS COMPRISING BINARY ALLOYS OF TITANIUM 失效
标题翻译：包含钛的二元合金的放射性标记
公开(公告)号：US20080288056A1
公开(公告)日：2008-11-20
申请号：US11748797
申请日：2007-05-15
申请人： John A. Simpson , John F. Boylan
发明人： John A. Simpson , John F. Boylan
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2250/0098
摘要： There is disclosed a radiopaque marker comprising a binary alloy of titanium and one binary element selected from platinum, palladium, rhodium, and gold. There is also disclosed various medical devices, such as stents, guidewires and embolic filters, that have the radiopaque marker attached thereto. Methods of attaching the radiopaque marker to the medical devices, such as by welding, are also disclosed.
摘要翻译：公开了一种不透射线的标记，其包括钛的二元合金和选自铂，钯，铑和金的一种二元元素。还公开了具有附着于其上的不透射线标记的各种医疗装置，例如支架，导丝和栓塞过滤器。还公开了将不透射线标记物附接到医疗装置的方法，例如通过焊接。

5. 发明授权

US06443971B1 System for, and method of, blocking the passage of emboli through a vessel 有权
公开(公告)号：US06443971B1
公开(公告)日：2002-09-03
申请号：US09469933
申请日：1999-12-21
申请人： John F. Boylan , John A. Simpson
发明人： John F. Boylan , John A. Simpson
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0078
摘要： A self-expanding filter has a deployable resilient distal portion with properties of passing fluid (e.g. blood) in a vessel (e.g. an artery) and blocking the passage of emboli in the fluid. The self-expanding filter is disposed in the vessel, in the direction of fluid flow in the vessel, with its resilient proximal and distal ends at positions past a lesion in the vessel. The distal end of the self-expanding filter is then deployed against the vessel wall. An interventional device, such as an expandable member (e.g. balloon) and expandable stent are disposed in the vessel at the position of the lesion in the vessel. The expandable member is then dilated to expand the expandable stent against the vessel wall and open the vessel at the lesion position. Fluid (blood) flows through the deployed distal end of the self-expanding filter and emboli created during the procedure are trapped by the deployed distal end of the filter. The expandable member is then collapsed after all of the emboli have been trapped by the deployed distal end of the self-expanding filter. The resilient proximal end of the self-expanding filter is thereafter deployed against the vessel wall. This causes the emboli to be trapped between the vessel wall and the proximal and distal ends of the self-expanding filter. Alternatively, the expandable member may be deflated and withdrawn from the vessel after the proximal end of the filter has been deployed against the wall of the vessel.

6. 发明授权

US08500786B2 Radiopaque markers comprising binary alloys of titanium 失效
标题翻译：包括钛的二元合金的不透射线标记
公开(公告)号：US08500786B2
公开(公告)日：2013-08-06
申请号：US11748797
申请日：2007-05-15
申请人： John A. Simpson , John F. Boylan
发明人： John A. Simpson , John F. Boylan
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2250/0098
摘要： There is disclosed a radiopaque marker comprising a binary alloy of titanium and one binary element selected from platinum, palladium, rhodium, and gold. There is also disclosed various medical devices, such as stents, guidewires and embolic filters, that have the radiopaque marker attached thereto. Methods of attaching the radiopaque marker to the medical devices, such as by welding, are also disclosed.
摘要翻译：公开了一种不透射线的标记，其包括钛的二元合金和选自铂，钯，铑和金的一种二元元素。还公开了具有附着于其上的不透射线标记的各种医疗装置，例如支架，导丝和栓塞过滤器。还公开了将不透射线标记物附接到医疗装置的方法，例如通过焊接。

7. 发明授权

US06896691B2 System for, and method of, blocking the passage of emboli through a vessel 有权
标题翻译：阻塞栓塞通过血管的系统和方法
公开(公告)号：US06896691B2
公开(公告)日：2005-05-24
申请号：US10175012
申请日：2002-06-19
申请人： John F. Boylan , John A. Simpson
发明人： John F. Boylan , John A. Simpson
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0078
摘要： A self-expanding filter has a deployable resilient distal portion with properties of passing fluid (e.g. blood) in a vessel (e.g. an artery) and blocking the passage of emboli in the fluid. The self-expanding filter is disposed in the vessel, in the direction of fluid flow in the vessel, with its resilient proximal and distal ends at positions past a lesion in the vessel. The distal end of the self-expanding filter is then deployed against the vessel wall. An interventional device, such as an expandable member (e.g. balloon) and expandable stent are disposed in the vessel at the position of the lesion in the vessel. The expandable member is then dilated to expand the expandable stent against the vessel wall and open the vessel at the lesion position. Fluid (blood) flows through the deployed distal end of the self-expanding filter and emboli created during the procedure are trapped by the deployed distal end of the filter. The expandable member is then collapsed after all of the emboli have been trapped by the deployed distal end of the self-expanding filter. The resilient proximal end of the self-expanding filter is thereafter deployed against the vessel wall. This causes the emboli to be trapped between the vessel wall and the proximal and distal ends of the self-expanding filter. Alternatively, the expandable member may be deflated and withdrawn from the vessel after the proximal end of the filter has been deployed against the wall of the vessel.
摘要翻译：自膨胀过滤器具有可展开的弹性远端部分，其具有使容器（例如动脉）中的流体（例如血液）通过并阻止栓塞在流体中通过的特性。自膨胀过滤器在容器中沿流体流动的方向设置在容器中，其弹性的近端和远端位于通过容器中的损伤处的位置。然后将自膨胀过滤器的远端展开抵靠血管壁。诸如可扩张构件（例如球囊）和可扩张支架的介入装置在容器中的病变位置处设置在容器中。然后使可膨胀构件膨胀，使可膨胀支架膨胀抵靠血管壁，并在病变位置打开血管。流体（血液）流过自扩张过滤器的部署的远端，并且在过程期间产生的栓塞被部署的过滤器的远端捕获。所有的栓塞已经被自扩张过滤器的展开的远端所困住，然后可膨胀构件被折叠。自膨胀过滤器的弹性近端随后部署在血管壁上。这导致栓塞被捕获在血管壁与自膨胀过滤器的近端和远端之间。或者，在过滤器的近端已经相对于容器的壁展开之后，可膨胀构件可以从容器中放气并从容器中取出。

8. 发明授权

US07938843B2 Devices configured from heat shaped, strain hardened nickel-titanium 有权
标题翻译：由热变形硬化镍钛构成的器件
公开(公告)号：US07938843B2
公开(公告)日：2011-05-10
申请号：US10457218
申请日：2003-06-09
申请人： John F. Boylan , Keif Fitzgerald , Zhi Cheng Lin
发明人： John F. Boylan , Keif Fitzgerald , Zhi Cheng Lin
IPC分类号： A61M29/00 , A61F11/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2210/0023 , A61F2230/0006 , A61F2230/0067 , A61M2025/09141 , C22F1/006
摘要： Cold worked nickel-titanium alloys that have linear pseudoelastic behavior without a phase transformation or onset of stress-induced martensite as applied to a medical device having a strut formed body deployed from a sheath is disclosed. In one application, an embolic protection device that employs a linear pseudoelastic nitinol self-expanding strut assembly with a small profile delivery system for use with interventional procedures is disclosed. The expandable strut assembly is covered with a filter element and both are compressed into a restraining sheath for delivery to a deployment site downstream and distal to an interventional procedure. Once at the desired site, the restraining sheath is retracted to deploy the embolic protection device, which captures flowing emboli generated during the interventional procedure. Linear pseudoelastic nitinol is used in the medical device as distinct from non-linear pseudoelastic (i.e., superelastic) nitinol.
摘要翻译：公开了一种冷加工的镍 - 钛合金，其具有线性假弹性特性，而不会发生应变诱发马氏体的相变或起始应用于具有从护套展开的支柱成形体的医疗装置。在一个应用中，公开了一种栓塞保护装置，其采用线性假弹性镍钛诺自扩张支架组件，其具有用于介入程序的小型轮廓输送系统。可膨胀支柱组件被过滤元件覆盖，并且两者被压缩成约束护套，用于递送到介入过程下游和远端的部署部位。一旦在期望的位置，约束护套被缩回以部署栓塞保护装置，其捕获在介入手术期间产生的流动栓塞。在医疗装置中使用线性假弹性镍钛诺不同于非线性假弹性（即超弹性）镍钛诺。

9. 发明授权

US07918011B2 Method for providing radiopaque nitinol alloys for medical devices 有权
标题翻译：为医疗器械提供不透射线的镍钛诺合金的方法
公开(公告)号：US07918011B2
公开(公告)日：2011-04-05
申请号：US11870262
申请日：2007-10-10
申请人： John F. Boylan , Daniel L. Cox
发明人： John F. Boylan , Daniel L. Cox
IPC分类号： B23P13/04 , A61F2/06
CPC分类号： A61F2/915 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0013 , A61F2250/0098 , A61L31/022 , A61L31/18 , A61L2400/16 , C22C19/00 , Y10S623/901 , Y10T29/49995
摘要： A radiopaque nitinol medical device such as a stent for use with or implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element selected from the group of chemical elements consisting of iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, or hafnium. The added ternary element improves the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same and strut pattern coated with a thin layer of gold. The nitinol stent has improved radioplacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility.
摘要翻译：公开了一种不透射线的镍钛诺医疗装置，例如用于或植入体腔内的支架。支架由镍 - 钛或镍钛诺等超弹性合金制成，并且包括选自由铱，铂，金，铼，钨，钯，铑，钽，银，钌等组成的化学元素组的三元元素，或铪。添加的三元元素提高了镍钛诺支架的不透射线能力，与不锈钢支架相同，并且镀有薄层金的支柱图案。镍钛诺支架具有改善的放射性，但仍然保持其超弹性和形状记忆行为，并进一步保持薄的支柱/壁厚以获得高灵活性。

10. 发明授权

US06881542B1 Serine threonine kinase member, h2520-59 失效
标题翻译：丝氨酸苏氨酸激酶成员，h2520-59
公开(公告)号：US06881542B1
公开(公告)日：2005-04-19
申请号：US09909474
申请日：2001-07-19
申请人： John F. Boylan , Alex J. Bowers
发明人： John F. Boylan , Alex J. Bowers
IPC分类号： C12N9/64 , C12Q1/68 , C07H21/04 , C12N5/00 , C12N9/20 , C12N15/00
CPC分类号： C12N9/6424 , C12Q1/6886 , C12Q2600/136 , C12Q2600/156
摘要： The present invention relates to a serine threonine kinase. The invention also relates to nucleic acids encoding the kinase, vectors, host cells, antibodies and recombinant methods for producing the h2520-59 polypeptide. In addition, the invention discloses therapeutic, diagnostic and research utilities for h2520-59 and related products.
摘要翻译：本发明涉及丝氨酸苏氨酸激酶。本发明还涉及编码激酶，载体，宿主细胞，抗体的核酸和用于产生h2520-59多肽的重组方法。此外，本发明公开了用于h2520-59及相关产品的治疗，诊断和研究用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式