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1. 发明申请

US20060079496A1 Agglomerates by crystallisation 审中-公开
标题翻译：通过结晶聚集
公开(公告)号：US20060079496A1
公开(公告)日：2006-04-13
申请号：US11290185
申请日：2005-11-30
申请人： Johannes Booij , Geertruida Lefferts
发明人： Johannes Booij , Geertruida Lefferts
IPC分类号： A61K31/43 , A61K31/407 , C07D487/08
CPC分类号： C07D503/00 , A61K9/1688 , A61K31/424 , A61K31/43 , C07D499/00 , Y10T428/2982 , A61K31/42 , A61K2300/00
摘要： The present invention describes novel agglomerates in crystalline form of β-lactum compounds, Furthermore, a process for the preparation of said agglomerates, wherein a solution or suspension of at least one β-lactum compound in a solvent is mixed with one or more anti-solvents has been described.
摘要翻译：本发明描述了β-内酯化合物的结晶形式的新型附聚物。此外，制备所述附聚物的方法，其中将至少一种β-内酯化合物在溶剂中的溶液或悬浮液与一种或多种抗坏血酸混合，已经描述了溶剂。

2. 发明授权

US06979735B1 Agglomerates by crystallization 失效
标题翻译：聚结物通过结晶
公开(公告)号：US06979735B1
公开(公告)日：2005-12-27
申请号：US09937834
申请日：2000-04-03
申请人： Johannes Booij , Ageeth Geertruida Lefferts
发明人： Johannes Booij , Ageeth Geertruida Lefferts
IPC分类号： A61K9/16 , A61K31/424 , A61K31/43 , C07D499/00 , C07D503/00 , C07D503/18
CPC分类号： C07D503/00 , A61K9/1688 , A61K31/424 , A61K31/43 , C07D499/00 , Y10T428/2982 , A61K31/42 , A61K2300/00
摘要： The present invention describes novel agglomerates in crystalline form of β-lactam compounds. Furthermore, a process for the preparation of said agglomerates, wherein a solution or suspension of at least one β-lactam compound in a solvent is mixed with one or more anti-solvents has been described.
摘要翻译：本发明描述了β-内酰胺化合物的结晶形式的新型附聚物。此外，已经描述了制备所述附聚物的方法，其中将至少一种β-内酰胺化合物在溶剂中的溶液或悬浮液与一种或多种抗溶剂混合。

3. 发明申请

US20110045082A1 AGGLOMERATES BY CRYSTALLISATION 审中-公开
标题翻译：通过CRYSTALLISATION AGAGOMERATE
公开(公告)号：US20110045082A1
公开(公告)日：2011-02-24
申请号：US12748167
申请日：2010-03-26
申请人： Johannes Booij , Geertruida Ageeth Lefferts
发明人： Johannes Booij , Geertruida Ageeth Lefferts
IPC分类号： A61K9/14 , C07D503/18 , A61K31/424 , A61K31/43 , A61P31/04 , B32B5/16
CPC分类号： C07D503/00 , A61K9/1688 , A61K31/424 , A61K31/43 , C07D499/00 , Y10T428/2982 , A61K31/42 , A61K2300/00
摘要： The present invention describes novel agglomerates in crystalline form of β-lactum compounds, Furthermore, a process for the preparation of said agglomerates, wherein a solution or suspension of at least one β-lactum compound in a solvent is mixed with one or more anti-solvents has been described.
摘要翻译：本发明描述了结晶形式的β-乳糖化合物的新型附聚物。此外，制备所述附聚物的方法，其中将至少一种β-乳酸酯化合物在溶剂中的溶液或悬浮液与一种或多种已经描述了抗溶剂。

4. 发明授权

US4769085A Method for cleaning a steam generator 失效
标题翻译：清洁蒸汽发生器的方法
公开(公告)号：US4769085A
公开(公告)日：1988-09-06
申请号：US925176
申请日：1986-10-31
申请人： Johannes Booij
发明人： Johannes Booij
IPC分类号： B08B3/02 , B08B9/053 , F22B37/48 , F28G15/04 , B08B5/04
CPC分类号： F28G15/04 , B08B3/02 , F22B37/483
摘要： Through two accesses lying substantially opposite one another, above the bottom of the steam generator, a high-pressure lance carrying at its end a spray head, is brought between bundle portions of a U-shaped pipe bundle. The two lances are simultaneously intermittently shifted and between the shiftings, when the spray heads may spray between the rows of the pipe bundle, the heads are swung to-and-fro over 180.degree.. At least during said swinging, liquid is sprayed through said heads under a pressure higher than 170 bars and with a total flow rate for the two spray heads of more than 150 liters per minute. The used liquid is sucked away from the bottom with a total sucking capacity which is markedly higher than said flow rate.
摘要翻译：通过在蒸汽发生器底部之上大致相对的两个通道，在其端部承载有喷头的高压喷枪被带到U形管束的束部之间。两个喷枪同时间歇地移动，并且在移动之间，当喷头可能在管束的行之间喷射时，头部在180度上摆动。至少在所述摆动期间，液体在高于170巴的压力下喷射通过所述头部，并且两个喷头的总流速为每分钟超过150升。所使用的液体从底部吸出，总吸油量明显高于所述流速。

5. 发明授权

US4756769A Method for cleaning with high pressure an evaporator and device used thereby 失效
标题翻译：用于高压清洗蒸发器的方法和由此使用的装置
公开(公告)号：US4756769A
公开(公告)日：1988-07-12
申请号：US4245
申请日：1987-01-05
申请人： Johannes Booij
发明人： Johannes Booij
IPC分类号： B01D1/30 , B08B9/093 , B08B9/00
CPC分类号： B01D1/30 , B08B9/0936
摘要： The spaces into which the vessel is divided by means of horizontal perforated partions are successively cleaned from top to bottom. Firstly the uppermost space is cleaned: the cover of the access to the space is removed, through the access a high-pressure lance is equipped with a spray head comprising a body rotatable about the lance axis and spray arms rotatably mounted on said body and liquid is sprayed with a pressure lying between 35 and 50 MPa. Then the middle space is cleaned: the cover of the access to the space is removed, through the access a high-pressure lance is equipped with a fixed spray head provided with spray openings directed in various directions and liquid is sprayed with a pressure lying between 50 to 70 MPa. Finally the lowermost space is cleaned in the same way as the uppermost space. The cleaning liquid is discharged through the outlet in the vessel bottom.
摘要翻译：通过水平穿孔部分将容器分开的空间从上到下连续地清洁。首先清洁最上面的空间：去除对空间的通路的盖子，通过通道，高压喷枪配备有喷头，喷头包括可围绕喷枪轴线旋转的主体和可旋转地安装在所述主体和液体上的喷射臂在35至50MPa之间的压力下喷雾。然后中间空间被清洁：取出空间的通道的盖子通过高压喷枪配备有固定的喷头，其具有指向各个方向的喷射开口，液体喷射在压力介于 50〜70MPa。最后，最上面的空间以与最上面的空间相同的方式进行清洁。清洗液通过容器底部的出口排出。

6. 发明授权

US4620881A Method for cleaning a steam generator 失效
标题翻译：清洁蒸汽发生器的方法
公开(公告)号：US4620881A
公开(公告)日：1986-11-04
申请号：US609802
申请日：1984-05-14
申请人： Johannes Booij
发明人： Johannes Booij
IPC分类号： B08B3/02 , B08B9/023 , F22B37/48 , F28G15/04 , B08B5/04
CPC分类号： F28G15/04 , B08B3/02 , F22B37/483
摘要： Through two accesses lying substantially opposite one another, above the bottom of the steam generator, a high-pressure lance carrying at its end a spray head, is brought between the pipes of the pipe bundle. The two lances are simultaneously intermittently shifted inwards or outwards and between the shiftings, when the spray heads may spray between the rows of the pipe bundle, the lances are swung to-and-fro over 180.degree.. At least during said swinging, liquid is sprayed through said heads under a pressure higher than 200 bars and with a total flow rate for the two spray heads of more than 200 liters per minute. The used liquid is sucked away from the bottom with a total sucking capacity which is markedly higher than said flow rate.
摘要翻译：通过两个彼此相对的通道，位于蒸汽发生器底部的上方，在管束的管道之间带有一个高压喷枪，其端部带有喷头。两个喷枪同时间断地向内或向外移动，并且在喷头之间可能在管束排之间喷洒时，喷枪在180度左右摆动。至少在所述摆动期间，液体在高于200巴的压力下喷射通过所述头部，并且两个喷头的总流速大于每分钟200升。所使用的液体从底部吸出，总吸油量明显高于所述流速。

7. 发明授权

US4565206A Apparatus for cleaning a steam generator by means of a high-pressure lance 失效
标题翻译：用于通过高压喷枪清洁蒸汽发生器的装置
公开(公告)号：US4565206A
公开(公告)日：1986-01-21
申请号：US609112
申请日：1984-05-11
申请人： Johannes Booij
发明人： Johannes Booij
IPC分类号： F22B37/48 , F23J3/02
CPC分类号： F22B37/483
摘要： The high-pressure lance is shiftably mounted in a bearing bush which is swingably mounted in a base which is to be secured over an opening in the wall of the steam generator. On the base are mounted a revolving cylinder which can swing the bearing bush to-and-fro over 180.degree. and a cylinder-piston unit which can shift the lance. A pneumatic control mechanism couples the lance either by means of clamping-cylinders to the bearing bush during its swinging or by means of another clamping cylinder to the piston of the cylinder-piston unit during its shifting.
摘要翻译：高压喷枪可移动地安装在轴承衬套中，该轴承衬套可摆动地安装在要固定在蒸汽发生器的壁的开口上的基座中。在底座上安装有一个可以使轴承衬套在180度左右摆动的旋转圆筒和一个可以移动喷枪的气缸 - 活塞单元。气动控制机构在其摆动期间通过夹紧缸将轴杆连接到轴承衬套，或者通过另一个夹紧缸将其移动到气缸 - 活塞单元的活塞。

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