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1. 发明申请

US20100203513A1 MICRORNA AS BIOMARKER IN CANCER 失效
标题翻译： MICRORNA作为生物标记在癌症
公开(公告)号：US20100203513A1
公开(公告)日：2010-08-12
申请号：US12513007
申请日：2007-10-30
申请人： Jingfang Ju , Yaguang Xi , Nakajima Go
发明人： Jingfang Ju , Yaguang Xi , Nakajima Go
IPC分类号： C12Q1/68 , C07H21/00
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/178
摘要： The present invention relates to the discovery of certain microRNAs that correlate with certain information regarding cancer. The microRNAs of the invention are selected from the group consisting of hsa-miR-15b, hsa-miR-181b, hsa-miR-191, hsa-miR-200c, and hsa-let-7g. If the expression of these microRNAs is increase, then the increased expression of these microRNAs is diagnostic for cancer, characterizes the cancer, prognosticates an expected response to cancer treatments, and/or prognosticates an expected survival of a patient. Embodiments of this discovery include a method, composition, kit and isolated nucleic acid.
摘要翻译：本发明涉及与关于癌症的某些信息相关的某些微小RNA的发现。本发明的微小RNA选自hsa-miR-15b，hsa-miR-181b，hsa-miR-191，hsa-miR-200c和hsa-let-7g。如果这些microRNA的表达增加，则这些microRNA的表达增加是癌症的诊断，癌症的特征，预测对癌症治疗的预期响应和/或预测患者的预期存活。该发现的实施方案包括方法，组合物，试剂盒和分离的核酸。

2. 发明授权

US08343719B2 Microrna as biomarker in cancer 失效
标题翻译： Microrna作为癌症中的生物标志物
公开(公告)号：US08343719B2
公开(公告)日：2013-01-01
申请号：US12513007
申请日：2007-10-30
申请人： Jingfang Ju , Yaguang Xi , Nakajima Go
发明人： Jingfang Ju , Yaguang Xi , Nakajima Go
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/178
摘要： The present invention relates to the discovery of certain microRNAs that correlate with certain information regarding cancer. The microRNAs of the invention are selected from the group consisting of hsa-miR-15b, hsa-miR-181b, hsa-miR-191, hsa-miR-200c, and hsa-let-7g. If the expression of these microRNAs is increase, then the increased expression of these microRNAs is diagnostic for cancer, characterizes the cancer, prognosticates an expected response to cancer treatments, and/or prognosticates an expected survival of a patient. Embodiments of this discovery include a method, composition, kit and isolated nucleic acid.
摘要翻译：本发明涉及与关于癌症的某些信息相关的某些微小RNA的发现。本发明的微小RNA选自hsa-miR-15b，hsa-miR-181b，hsa-miR-191，hsa-miR-200c和hsa-let-7g。如果这些microRNA的表达增加，则这些微小RNA的表达增加是对癌症的诊断，表征癌症，预测对癌症治疗的预期响应和/或预测患者的预期存活。该发现的实施方案包括方法，组合物，试剂盒和分离的核酸。

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