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1. 发明申请

US20120302880A1 SYSTEM AND METHOD FOR SPECIFICITY-BASED MULTIMODALITY THREE- DIMENSIONAL OPTICAL TOMOGRAPHY IMAGING 审中-公开
标题翻译：基于特异性多模态三维光学成像的系统和方法
公开(公告)号：US20120302880A1
公开(公告)日：2012-11-29
申请号：US13535774
申请日：2012-06-28
申请人： Jie TIAN , Xin YANG , Kai LIU , Dong HAN , Chenghu QIN
发明人： Jie TIAN , Xin YANG , Kai LIU , Dong HAN , Chenghu QIN
IPC分类号： A61B6/02 , A61B6/03
CPC分类号： A61B6/032 , A61B5/0035 , A61B5/0073 , A61B6/0407 , A61B6/5247 , G06T11/006 , G06T2211/424
摘要： A system and method for specificity-based multimodality three-dimensional optical tomography imaging comprises steps of: optical imaging to obtain a light intensity of body surface optical signal of an imaging target; CT imaging to obtain structure volume data; establishing an equation representing a linear relationship between the distribution of the obtained light intensity of body surface optical signal of the imaging target, the obtained CT discrete mesh data and the distribution of unknown internal self-luminescence light sources; establishing a dynamic sparse regularization target function in every iteration for the equation; and reconstructing a tomography image. The present invention well considers the optical specificity of tissue, in which there is a non-uniform optical characteristic parameter distribution within the same tissue when finite element modeling is used, which is closer to the real situation, so that an accurate imaging effect is achieved.
摘要翻译：一种用于基于特征的多模态三维光学层析成像的系统和方法，包括以下步骤：获得成像目标的体表光信号的光强度的光学成像; CT成像获取结构体数据; 建立表示所获得的成像对象的体表光信号的光强度的分布与所获得的CT离散网格数据与未知内部自发光光源的分布之间的线性关系的方程式; 在该方程的每次迭代中建立动态稀疏正则化目标函数; 并重建断层图像。本发明很好地考虑到组织的光学特异性，其中在使用有限元建模时，在相同组织内存在不均匀的光学特征参数分布，其更接近实际情况，从而实现精确的成像效果。

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