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1. 发明申请

US20090254177A1 Method and Apparatuses for Deploying Minimally-Invasive Heart Valves 有权
标题翻译：用于部署微创心脏瓣膜的方法和装置
公开(公告)号：US20090254177A1
公开(公告)日：2009-10-08
申请号：US12488480
申请日：2009-06-19
申请人： Jibin Yang , Matthew Lane Pease , Scott Hyler Heneveld, SR. , Brandon G. Walsh
发明人： Jibin Yang , Matthew Lane Pease , Scott Hyler Heneveld, SR. , Brandon G. Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2409 , A61F2/2412 , A61F2/2427
摘要： A system for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The heart valve may be a rolled-type valve and the deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the outer layer of the head valve. Controlled radial movement of the fingers regulates the unwinding of the rolled heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment mechanism may include an umbrella structure that forces the rolled valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means.
摘要翻译：用于将自扩张心脏瓣膜递送和部署到诸如主动脉瓣环的植入部位的系统包括与阀门接合并调节其近端和远端的膨胀速率的展开机构。心脏瓣膜可以是卷状阀，并且展开机构可以包括多个远侧指状物和与头部阀门的外层接合的多个近端指状物。手指的受控径向运动调节卷绕的心脏瓣膜的展开。在气囊膨胀之前可以将手指移除以完全膨胀阀，或者为了这个目的，手指可以重新定位到阀的内部。展开机构可以包括伞形结构，其将卷起的阀向外推入其完全展开的构型。或者，与阀上的一个或多个齿轮啮合的齿轮轴可用于调节阀的膨胀。可以使用稳定气囊来相对于植入位置轴向地和径向地定位展开机构。输送和展开机构的操作方法包括利用相同或不同的装置来调节阀的自膨胀速率并迫使阀向外进入其完全膨胀的构型。

2. 发明授权

US07556646B2 Methods and apparatuses for deploying minimally-invasive heart valves 有权
标题翻译：用于部署微创心脏瓣膜的方法和装置
公开(公告)号：US07556646B2
公开(公告)日：2009-07-07
申请号：US09951701
申请日：2001-09-13
申请人： Jibin Yang , Scott Hyler Heneveld, Sr. , Matthew Lane Pease , Brandon G. Walsh
发明人： Jibin Yang , Scott Hyler Heneveld, Sr. , Matthew Lane Pease , Brandon G. Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2409 , A61F2/2412 , A61F2/2427
摘要： A system for delivering and deploying a self-expandable heart valve includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the end portions of the heart valve. Controlled radial movement of the fingers regulates the expansion of the heart valve such that the proximal and distal ends radially expand at the same rate. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means.
摘要翻译：一种用于递送和展开自扩张型心脏瓣膜的系统包括与阀门接合并调节其近端和远端的膨胀速率的展开机构。展开机构可以包括接合心脏瓣膜的端部的多个远端指状物和多个近端指状物。手指的受控径向移动调节心脏瓣膜的膨胀，使得近端和远端以相同的速率径向扩张。可以使用稳定气囊来相对于植入位置轴向地和径向地定位展开机构。输送和展开机构的操作方法包括利用相同或不同的装置来调节阀的自膨胀速率并迫使阀向外进入其完全膨胀的构型。

3. 发明授权

US08740975B2 Methods and apparatuses for deploying minimally-invasive heart valves 有权
标题翻译：用于部署微创心脏瓣膜的方法和装置
公开(公告)号：US08740975B2
公开(公告)日：2014-06-03
申请号：US12488480
申请日：2009-06-19
申请人： Jibin Yang , Matthew Lane Pease , Scott Hyler Heneveld, Sr. , Brandon G. Walsh
发明人： Jibin Yang , Matthew Lane Pease , Scott Hyler Heneveld, Sr. , Brandon G. Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2409 , A61F2/2412 , A61F2/2427
摘要： A method for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus. The deployment step may include engaging an outer surface of the heart valve with a plurality of distal fingers and a plurality of proximal fingers. Controlled radial movement of the fingers regulates the expansion of the heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment step may include an umbrella structure that forces the valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation.
摘要翻译：用于将自扩张型心脏瓣膜递送和部署到诸如主动脉环的植入部位的方法。展开步骤可以包括使心脏瓣膜的外表面与多个远端指状物和多个近端指状物接合。手指的受控径向运动调节心脏瓣膜的扩张。在气囊膨胀之前可以将手指移除以完全膨胀阀，或者为了这个目的，手指可以重新定位到阀的内部。展开步骤可以包括将阀门向外推入其完全展开构型的伞形结构。或者，与阀上的一个或多个齿轮啮合的齿轮轴可用于调节阀的膨胀。可以使用稳定气囊来相对于植入位置轴向地和径向地定位展开机构。

4. 发明申请

US20120179243A1 METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES 有权
标题翻译：用于配置微小入场心脏瓣膜的方法和装置
公开(公告)号：US20120179243A1
公开(公告)日：2012-07-12
申请号：US13350730
申请日：2012-01-13
申请人： Jibin Yang , Scott Hyler Heneveld, SR. , Matthew Lane Pease , Brandon G. Walsh
发明人： Jibin Yang , Scott Hyler Heneveld, SR. , Matthew Lane Pease , Brandon G. Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2409 , A61F2/2412 , A61F2/2427
摘要： A method for replacing native valve function of a diseased aortic valve in a patient is provided. The method comprises: (a) guiding a catheter system having a balloon through the vasculature of the patient; (b) guiding an artificial heart valve assembly through the vasculature of the patient; (c) while the catheter system is in the patient's vasculature, positioning the artificial heart valve assembly about the balloon of the catheter system; (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve; (e) while the patient's heart is beating, expanding the artificial heart valve assembly in the region of the diseased aortic valve; and (f) withdrawing the catheter system from the patient's vasculature.
摘要翻译：提供了一种用于替换患者中患病主动脉瓣的天然瓣膜功能的方法。该方法包括：（a）通过患者的脉管系统引导具有气囊的导管系统; （b）引导人造心脏瓣膜组件通过患者的脉管系统; （c）当导管系统处于患者脉管系统中时，将人造心脏瓣膜组件围绕导管系统的球囊定位; （d）将人造心脏瓣膜组件递送到患病主动脉瓣的区域; （e）当患者的心脏跳动时，在患病主动脉瓣的区域内扩张人造心脏瓣膜组件; 和（f）将导管系统从患者的脉管系统中取出。

5. 发明授权

US06723122B2 Container and method for storing and delivering minimally-invasive heart valves 有权
标题翻译：用于储存和输送微创心脏瓣膜的容器和方法
公开(公告)号：US06723122B2
公开(公告)日：2004-04-20
申请号：US09945392
申请日：2001-08-30
申请人： Jibin Yang , Matthew Lane Pease , Brandon G. Walsh
发明人： Jibin Yang , Matthew Lane Pease , Brandon G. Walsh
IPC分类号： A61F224
CPC分类号： A61F2/2415 , A61F2/0095
摘要： Storage containers for expandable heart valves for minimally invasive valve replacement surgeries are disclosed. The containers permit an expandable valve to be stored in its expanded configuration and then converted to its contracted configuration while still in the container. A mechanism incorporated into the container facilitates the conversion. For example, the container may have a base and a lid, and a crank manipulable from outside. The lid actuates a key within the container that engages the valve to perform the contraction. If the valve is a spirally wound type of expandable valve, the key may be attached to an inner side edge and rotated to wind the valve into a tight spiral. A drain in the container may facilitate removal of a preservative solution so that the valve can be seen during the contraction process, or so that the valve can be rinsed while still within the container.
摘要翻译：公开了用于微创瓣膜置换手术的可扩张心脏瓣膜的储存容器。容器允许可膨胀阀以其膨胀构型存储，然后在仍然在容器中的同时转换成其收缩构型。结合到容器中的机构有助于转化。例如，容器可以具有底座和盖子，以及可从外部操纵的曲柄。盖子致动容器内的接合阀门以执行收缩的钥匙。如果阀是螺旋卷绕式可膨胀阀，则钥匙可以附接到内侧边缘并旋转以将阀卷绕成紧密螺旋。容器中的排水口可以有助于去除防腐溶液，使得在收缩过程中可以看到阀门，或者使得阀门仍然在容器内被冲洗。

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