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1. 发明授权

US08384038B2 Readout electronics for photon counting and energy discriminating detectors 有权
标题翻译：用于光子计数和能量鉴别检测器的读出电子装置
公开(公告)号：US08384038B2
公开(公告)日：2013-02-26
申请号：US12490903
申请日：2009-06-24
申请人： Jianjun Guo , Naresh Kesavan Rao , John Eric Tkaczyk , Yanfeng Du , Naveen Chandra
发明人： Jianjun Guo , Naresh Kesavan Rao , John Eric Tkaczyk , Yanfeng Du , Naveen Chandra
IPC分类号： G01T1/24
CPC分类号： G01T1/247
摘要： A data acquisition system includes a charge-sensitive amplifier (CSA) configured to receive a charge from an x-ray detector, the CSA includes a high-gain electronic voltage amplifier, an electrical energy storage device coupled with the amplifier, and an electrical resistor coupled with the amplifier. The data acquisition system includes a baseline sampling circuit configured to receive an output from the CSA and to sample a baseline signal from the CSA, at least one discriminator coupled to an output of the CSA and to an output of the baseline sampling circuit, the at least one discriminator configured to output a voltage if the output of the CSA exceeds a threshold, and a counter coupled to an output of the discriminator and configured to output a digital signal indicative of a photon count received at the x-ray detector and based on the output from the CSA and on the signal from the CSA.
摘要翻译：数据采集系统包括被配置为从X射线检测器接收电荷的电荷敏感放大器（CSA），CSA包括高增益电子电压放大器，与放大器耦合的电能存储装置和电阻器加上放大器。数据采集系统包括基准采样电路，其被配置为从CSA接收输出并从CSA采样基线信号，耦合到CSA的输出和基线采样电路的输出的至少一个鉴别器，如果所述CSA的输出超过阈值，则配置成输出电压的至少一个鉴别器，以及耦合到所述鉴别器的输出并被配置为输出指示在所述x射线检测器处接收的光子计数的数字信号的计数器，并且基于 CSA的输出和CSA的信号。

2. 发明申请

US20100329425A1 READOUT ELECTRONICS FOR PHOTON COUNTING AND ENERGY DISCRIMINATING DETECTORS 有权
标题翻译：用于光电计数和能量鉴别检测器的读出电子
公开(公告)号：US20100329425A1
公开(公告)日：2010-12-30
申请号：US12490903
申请日：2009-06-24
申请人： Jianjun Guo , Naresh Kesavan Rao , John Eric Tkaczyk , Yanfeng Du , Naveen Chandra
发明人： Jianjun Guo , Naresh Kesavan Rao , John Eric Tkaczyk , Yanfeng Du , Naveen Chandra
IPC分类号： H05G1/26 , G01T1/24 , H05G1/28
CPC分类号： G01T1/247
摘要： A data acquisition system includes a charge-sensitive amplifier (CSA) configured to receive a charge from an x-ray detector, the CSA includes a high-gain electronic voltage amplifier, an electrical energy storage device coupled with the amplifier, and an electrical resistor coupled with the amplifier. The data acquisition system includes a baseline sampling circuit configured to receive an output from the CSA and to sample a baseline signal from the CSA, at least one discriminator coupled to an output of the CSA and to an output of the baseline sampling circuit, the at least one discriminator configured to output a voltage if the output of the CSA exceeds a threshold, and a counter coupled to an output of the discriminator and configured to output a digital signal indicative of a photon count received at the x-ray detector and based on the output from the CSA and on the signal from the CSA.
摘要翻译：数据采集系统包括被配置为从X射线检测器接收电荷的电荷敏感放大器（CSA），CSA包括高增益电子电压放大器，与放大器耦合的电能存储装置和电阻器加上放大器。数据采集系统包括基准采样电路，其被配置为从CSA接收输出并从CSA采样基线信号，耦合到CSA的输出和基线采样电路的输出的至少一个鉴别器，如果所述CSA的输出超过阈值，则配置成输出电压的至少一个鉴别器，以及耦合到所述鉴别器的输出并被配置为输出指示在所述x射线检测器处接收的光子计数的数字信号的计数器，并且基于 CSA的输出和CSA的信号。

3. 发明授权

US08787519B2 System and method of optimizing a representation of dual energy spectral CT images 有权
标题翻译：优化双能谱CT图像表示的系统和方法
公开(公告)号：US08787519B2
公开(公告)日：2014-07-22
申请号：US13174825
申请日：2011-07-01
申请人： Jiahua Fan , Naveen Chandra , Bruno Kristiaan Bernard De Man
发明人： Jiahua Fan , Naveen Chandra , Bruno Kristiaan Bernard De Man
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/482 , A61B6/032 , A61B6/4241 , A61B6/5258
摘要： An imaging system includes an x-ray source, a detector, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of a first basis material and a second basis material, generate a first basis material image and a second basis material image using the decomposed projection CT data, generate a first monochromatic image from the first basis material image and the second basis material image at a first energy that is selected based on an amount of correlated noise at the first energy, noise-reduce the first monochromatic image to generate a noise-reduced first monochromatic image, and generate a final monochromatic image based at least on the noise-reduced first monochromatic image.
摘要翻译：成像系统包括可操作地连接到检测器的X射线源，检测器，数据采集系统（DAS）以及可操作地连接到DAS的计算机。计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成第一基材和第二基材的投影CT数据，生成第一基材图像和第二基材图像使用分解的投影CT数据，以基于第一能量处的相关噪声量选择的第一能量从第一基材图像和第二基材图像生成第一单色图像，降低第一单色图像以产生噪声减小的第一单色图像，并且至少基于噪声减小的第一单色图像生成最终单色图像。

4. 发明授权

US08503750B2 Method and apparatus for reduction of metal artifacts in CT images 有权
标题翻译：减少CT图像中金属伪影的方法和装置
公开(公告)号：US08503750B2
公开(公告)日：2013-08-06
申请号：US12574502
申请日：2009-10-06
申请人： Thomas Matthew Benson , Naveen Chandra , David Allen Langan
发明人： Thomas Matthew Benson , Naveen Chandra , David Allen Langan
IPC分类号： A61B6/03
CPC分类号： G06T11/005 , A61B6/5258
摘要： A method and apparatus include acquisition of a view dataset based on x-rays received by a detector corresponding to a energy level, reconstruction of an initial image using the view dataset, the initial image comprising a plurality of metal voxels at respective metal voxel locations, and generation of a metal mask corresponding to the plurality of metal voxels within the initial image. The method and apparatus also include forward projection of the metal mask onto the view dataset to identify metal dexels in the view dataset, performance of a weighted interpolation based on the identified metal dexels to generate a completed view dataset, reconstruction of a final image using the completed view dataset, the final image comprising a plurality of image voxels corresponding to the metal voxel locations, and replacement of a portion of the plurality of image voxels corresponding to the metal voxel locations with smoothed metal values.
摘要翻译：一种方法和装置包括：基于由能量级对应的检测器接收的X射线获取视图数据集，使用视图数据集重构初始图像，初始图像包括在相应的金属体素位置处的多个金属体素，以及生成与初始图像内的多个金属体素相对应的金属掩模。所述方法和装置还包括将金属掩模向视图数据集向前投影以识别视图数据集中的金属像素，基于所识别的金属像素来执行加权内插以生成完整的视图数据集，使用完成的视图数据集，最终图像包括对应于金属体元位置的多个图像体素，以及用平滑的金属值替换与金属体元位置相对应的多个图像体素的一部分。

5. 发明授权

US08265227B2 Apparatus and method for calibrating an X-ray tube 有权
标题翻译：用于校准X射线管的装置和方法
公开(公告)号：US08265227B2
公开(公告)日：2012-09-11
申请号：US12646320
申请日：2009-12-23
申请人： John Moore Boudry , Sergio Lemaitre , Naveen Chandra
发明人： John Moore Boudry , Sergio Lemaitre , Naveen Chandra
IPC分类号： H05G1/34 , H05G1/50 , H05G1/08
CPC分类号： H05G1/46
摘要： An apparatus and method for calibrating an x-ray tube include a computer programmed to acquire a starter voltage/current value corresponding to a width, a length, or a position of a target focal spot capable of being generated by the x-ray tube. The computer is programmed to generate an electron beam and to steer the electron beam based on the starter voltage/current value. The computer is also programmed to steer the electron beam based on a value adjusted from the starter voltage/current value. The computer is programmed to calculate a final voltage/current value that is configured to generate the width, length, or position of the target focal spot based on the starter voltage/current value and the adjusted starter voltage/current value.
摘要翻译：用于校准X射线管的装置和方法包括被编程为获取对应于能够由X射线管产生的目标焦斑的宽度，长度或位置的起动器电压/电流值的计算机。计算机被编程为产生电子束并且基于起动器电压/电流值来控制电子束。计算机还被编程为基于从起动电压/电流值调整的值来引导电子束。计算机被编程为基于起动器电压/电流值和调整的启动器电压/电流值来计算被配置为产生目标焦点的宽度，长度或位置的最终电压/电流值。

6. 发明授权

US08199875B2 System and method of acquiring multi-energy CT imaging data 有权
标题翻译：获取多能CT成像数据的系统和方法
公开(公告)号：US08199875B2
公开(公告)日：2012-06-12
申请号：US12760862
申请日：2010-04-15
申请人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
发明人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
IPC分类号： A61B6/00
CPC分类号： A61B6/4035 , A61B6/032 , A61B6/4007 , A61B6/405 , A61B6/4241 , A61B6/482
摘要： A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to apply a first kVp for a first time period, apply a second kVp for a second time period, wherein the second time period is different from the first time period, acquire a first asymmetric view dataset during at least a portion of the first time period, acquire a second asymmetric view dataset during at least a portion of the second time period, and generate an image using the acquired first and second asymmetric view datasets.
摘要翻译： CT系统包括具有用于接收待扫描物体的开口的可旋转机架，以及被配置为在第一时间段施加第一kVp的控制器，在第二时间段施加第二kVp，其中第二时间段是不同的从所述第一时间段在所述第一时间段的至少一部分期间获取第一非对称视图数据集，在所述第二时间段的至少一部分期间获取第二非对称视图数据集，并且使用所获取的第一和第二时间段生成图像非对称视图数据集。

7. 发明授权

US07689399B1 Automatic extraction of design properties 有权
标题翻译：自动提取设计属性
公开(公告)号：US07689399B1
公开(公告)日：2010-03-30
申请号：US10931727
申请日：2004-08-31
申请人： Sudheendra G. Hangal , Naveen Chandra
发明人： Sudheendra G. Hangal , Naveen Chandra
IPC分类号： G06F17/50
CPC分类号： G06F17/504
摘要： A method for automatic extraction of design properties of a hardware design, is provided. The method includes running a hardware design simulation to generate simulation results for the hardware design. The simulation results are then analyzed to extract properties. The extracted properties can be a powerful tool for the design engineers and the test-writers to learn more about the functional coverage of the test suites.
摘要翻译：提供了一种自动提取硬件设计的设计特性的方法。该方法包括运行硬件设计仿真，以生成硬件设计的仿真结果。然后分析模拟结果以提取属性。提取的属性可以是设计工程师和测试人员更多地了解测试套件的功能覆盖的强大工具。

8. 发明授权

US09135728B2 System and method for multi-energy computed tomography imaging 有权
标题翻译：多能计算机断层成像系统和方法
公开(公告)号：US09135728B2
公开(公告)日：2015-09-15
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： G06T11/00 , A61B6/06 , A61B6/00 , G21K1/02 , A61B6/03 , G21K1/10 , H01J35/26 , H01J35/30
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

9. 发明授权

US08588494B2 System and method for material decomposition optimization in image domain 有权
标题翻译：图像域中物质分解优化的系统和方法
公开(公告)号：US08588494B2
公开(公告)日：2013-11-19
申请号：US12915195
申请日：2010-10-29
申请人： Bruno Kristiaan Bernard De Man , Jiang Hsieh , Naveen Chandra , Jed Douglas Pack , Jiahua Fan
发明人： Bruno Kristiaan Bernard De Man , Jiang Hsieh , Naveen Chandra , Jed Douglas Pack , Jiahua Fan
IPC分类号： G06K9/00 , A61B6/00 , G01N23/00 , G21K1/12 , H05G1/60
CPC分类号： H04B1/1638 , G06T11/008 , G06T2211/408
摘要： A system and method for material decomposition optimization in the image domain include a non-transitory computer readable medium has stored thereon a sequence of instructions which, when executed by a computer, causes the computer to access a reconstructed basis material image. For a first voxel of the reconstructed basis material image, the instructions also cause the computer to optimize a concentration of a pair of materials (a,b) in the first voxel exclusively in the image domain and based on a first probability based on random perturbations and a second probability based on random perturbations. The optimization is further based on a third probability based on known materials and a fourth probability based on concentrations of the pair of materials in a pair of voxels neighboring the first voxel.
摘要翻译：用于图像域中的材料分解优化的系统和方法包括其上存储有一系列指令的非瞬时计算机可读介质，所述指令序列当由计算机执行时使计算机访问重建的基础材料图像。对于重建的基材图像的第一体素，指令还使计算机优化仅在图像域中的第一体素中的一对材料（a，b）的浓度，并且基于基于随机扰动的第一概率和基于随机扰动的第二概率。优化进一步基于基于已知材料的第三概率和基于邻近第一体素的一对体素中的该对材料对的浓度的第四概率。

10. 发明申请

US20130266115A1 SYSTEM AND METHOD FOR MULTI-ENERGY COMPUTED TOMOGRAPHY IMAGING 有权
标题翻译：多功能计算机图像成像系统与方法
公开(公告)号：US20130266115A1
公开(公告)日：2013-10-10
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： A61B6/08 , A61B6/03
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

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