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1. 发明申请

US20110150175A1 APPARATUS AND METHOD FOR SPECTRAL PROJECTION IMAGING WITH FAST KV SWITCHING 有权
标题翻译：用快速KV切换进行光谱投影成像的装置和方法
公开(公告)号：US20110150175A1
公开(公告)日：2011-06-23
申请号：US12642945
申请日：2009-12-21
申请人： Jiang Hsieh , Naveen Chandra , Steven J. Woloschek , Robert F. Senzig
发明人： Jiang Hsieh , Naveen Chandra , Steven J. Woloschek , Robert F. Senzig
IPC分类号： H05G1/60 , G06K9/00
CPC分类号： A61B6/482 , A61B6/4021 , A61B6/4266 , A61B6/488 , G01T1/2985
摘要： A CT system includes a gantry, an x-ray source configured to project x-rays toward an object, an x-ray detector positioned to receive x-rays from the x-ray source that pass through the object, a generator configured to energize the x-ray source to a first voltage and to a second voltage that is distinct from the first voltage, and a controller configured to cause the gantry to position the source and generator at a circumferential position during an imaging session, pass the object through the opening during the imaging session, cause the generator to energize the x-ray source to the first voltage and to the second voltage, acquire imaging data while the generator energizes the x-ray source to the first voltage and to the second voltage while the rotatable gantry is at the circumferential position, and generate an image using the imaging data.
摘要翻译：一个CT系统包括一个配置成将x射线投射到物体的台架，x射线源，x射线探测器，其被定位成从X射线源接收穿过物体的x射线， x射线源到第一电压和不同于第一电压的第二电压;以及控制器，其被配置为使得台架在成像会话期间将源和发生器定位在圆周位置，使物体通过在成像会话期间打开，使得发生器将x射线源激励到第一电压和第二电压，获取成像数据，同时发生器将X射线源激励到第一电压和第二电压，同时可旋转龙门架处于圆周位置，并使用成像数据生成图像。

2. 发明授权

US08548118B2 Apparatus and method for spectral projection imaging with fast KV switching 有权
标题翻译：用于快速KV切换的光谱投影成像装置和方法
公开(公告)号：US08548118B2
公开(公告)日：2013-10-01
申请号：US12642945
申请日：2009-12-21
申请人： Jiang Hsieh , Naveen Chandra , Steven J. Woloschek , Robert F. Senzig
发明人： Jiang Hsieh , Naveen Chandra , Steven J. Woloschek , Robert F. Senzig
IPC分类号： G01N23/00
CPC分类号： A61B6/482 , A61B6/4021 , A61B6/4266 , A61B6/488 , G01T1/2985
摘要： A CT system includes a gantry, an x-ray source configured to project x-rays toward an object, an x-ray detector positioned to receive x-rays from the x-ray source that pass through the object, a generator configured to energize the x-ray source to a first voltage and to a second voltage that is distinct from the first voltage, and a controller configured to cause the gantry to position the source and generator at a circumferential position during an imaging session, pass the object through the opening during the imaging session, cause the generator to energize the x-ray source to the first voltage and to the second voltage, acquire imaging data while the generator energizes the x-ray source to the first voltage and to the second voltage while the rotatable gantry is at the circumferential position, and generate an image using the imaging data.
摘要翻译：一个CT系统包括一个配置成将x射线投射到物体的台架，x射线源，x射线探测器，其被定位成从X射线源接收穿过物体的x射线， x射线源到第一电压和不同于第一电压的第二电压;以及控制器，其被配置为使得台架在成像会话期间将源和发生器定位在圆周位置，使物体通过在成像会话期间打开，使得发生器将x射线源激励到第一电压和第二电压，获取成像数据，同时发生器将X射线源激励到第一电压和第二电压，同时可旋转龙门架处于圆周位置，并使用成像数据生成图像。

3. 发明授权

US08199875B2 System and method of acquiring multi-energy CT imaging data 有权
标题翻译：获取多能CT成像数据的系统和方法
公开(公告)号：US08199875B2
公开(公告)日：2012-06-12
申请号：US12760862
申请日：2010-04-15
申请人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
发明人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
IPC分类号： A61B6/00
CPC分类号： A61B6/4035 , A61B6/032 , A61B6/4007 , A61B6/405 , A61B6/4241 , A61B6/482
摘要： A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to apply a first kVp for a first time period, apply a second kVp for a second time period, wherein the second time period is different from the first time period, acquire a first asymmetric view dataset during at least a portion of the first time period, acquire a second asymmetric view dataset during at least a portion of the second time period, and generate an image using the acquired first and second asymmetric view datasets.
摘要翻译： CT系统包括具有用于接收待扫描物体的开口的可旋转机架，以及被配置为在第一时间段施加第一kVp的控制器，在第二时间段施加第二kVp，其中第二时间段是不同的从所述第一时间段在所述第一时间段的至少一部分期间获取第一非对称视图数据集，在所述第二时间段的至少一部分期间获取第二非对称视图数据集，并且使用所获取的第一和第二时间段生成图像非对称视图数据集。

4. 发明授权

US09135728B2 System and method for multi-energy computed tomography imaging 有权
标题翻译：多能计算机断层成像系统和方法
公开(公告)号：US09135728B2
公开(公告)日：2015-09-15
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： G06T11/00 , A61B6/06 , A61B6/00 , G21K1/02 , A61B6/03 , G21K1/10 , H01J35/26 , H01J35/30
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

5. 发明授权

US08588494B2 System and method for material decomposition optimization in image domain 有权
标题翻译：图像域中物质分解优化的系统和方法
公开(公告)号：US08588494B2
公开(公告)日：2013-11-19
申请号：US12915195
申请日：2010-10-29
申请人： Bruno Kristiaan Bernard De Man , Jiang Hsieh , Naveen Chandra , Jed Douglas Pack , Jiahua Fan
发明人： Bruno Kristiaan Bernard De Man , Jiang Hsieh , Naveen Chandra , Jed Douglas Pack , Jiahua Fan
IPC分类号： G06K9/00 , A61B6/00 , G01N23/00 , G21K1/12 , H05G1/60
CPC分类号： H04B1/1638 , G06T11/008 , G06T2211/408
摘要： A system and method for material decomposition optimization in the image domain include a non-transitory computer readable medium has stored thereon a sequence of instructions which, when executed by a computer, causes the computer to access a reconstructed basis material image. For a first voxel of the reconstructed basis material image, the instructions also cause the computer to optimize a concentration of a pair of materials (a,b) in the first voxel exclusively in the image domain and based on a first probability based on random perturbations and a second probability based on random perturbations. The optimization is further based on a third probability based on known materials and a fourth probability based on concentrations of the pair of materials in a pair of voxels neighboring the first voxel.
摘要翻译：用于图像域中的材料分解优化的系统和方法包括其上存储有一系列指令的非瞬时计算机可读介质，所述指令序列当由计算机执行时使计算机访问重建的基础材料图像。对于重建的基材图像的第一体素，指令还使计算机优化仅在图像域中的第一体素中的一对材料（a，b）的浓度，并且基于基于随机扰动的第一概率和基于随机扰动的第二概率。优化进一步基于基于已知材料的第三概率和基于邻近第一体素的一对体素中的该对材料对的浓度的第四概率。

6. 发明申请

US20130266115A1 SYSTEM AND METHOD FOR MULTI-ENERGY COMPUTED TOMOGRAPHY IMAGING 有权
标题翻译：多功能计算机图像成像系统与方法
公开(公告)号：US20130266115A1
公开(公告)日：2013-10-10
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： A61B6/08 , A61B6/03
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

7. 发明授权

US08363779B2 System and method of acquiring multi-energy CT imaging data 有权
标题翻译：获取多能CT成像数据的系统和方法
公开(公告)号：US08363779B2
公开(公告)日：2013-01-29
申请号：US13484707
申请日：2012-05-31
申请人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
发明人： Naveen Chandra , Xiaoye Wu , Thomas L. Toth , Jiang Hsieh
IPC分类号： A61B6/00 , H05G1/64 , G06K9/00
CPC分类号： A61B6/4035 , A61B6/032 , A61B6/4007 , A61B6/405 , A61B6/4241 , A61B6/482
摘要： A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller. The controller is configured to apply a first kVp for a first time period, apply a second kVp for a second time period, integrate two or more view datasets during the first time period, integrate one or more view datasets during the second time period, and generate an image using the datasets integrated during the first time period and during the second time period.
摘要翻译： CT系统包括具有用于接收待扫描物体的开口的可旋转机架和控制器。控制器被配置为在第一时间段内施加第一kVp，在第二时间段施加第二kVp，在第一时间段期间集成两个或更多个视图数据集，在第二时间段期间集成一个或多个视图数据集;以及使用在第一时间段期间和第二时间段期间集成的数据集生成图像。

8. 发明申请

US20120069952A1 SYSTEM AND METHOD OF SPECTRAL CALIBRATION AND BASIS MATERIAL DECOMPOSITION FOR X-RAY CT SYSTEMS 有权
标题翻译： X射线CT系统的光谱校准和基础材料分解系统与方法
公开(公告)号：US20120069952A1
公开(公告)日：2012-03-22
申请号：US12883631
申请日：2010-09-16
申请人： Xiaoye Wu , Dan Xu , Naveen Chandra , Zhanyu Ge , Jiang Hsieh , Daniel David Harrison , Mary Sue Kulpins
发明人： Xiaoye Wu , Dan Xu , Naveen Chandra , Zhanyu Ge , Jiang Hsieh , Daniel David Harrison , Mary Sue Kulpins
IPC分类号： A61B6/03
CPC分类号： A61B6/583 , A61B6/032 , A61B6/482 , A61B6/585
摘要： An imaging system includes an x-ray source that emits a beam of x-rays toward an object, a detector that receives high frequency electromagnetic energy attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to compute detector coefficients based on a static low kVp measurement and a static high kVp measurement, capture incident spectra at high and low kVp during fast kVp switching, compute effective X-ray incident spectra at high and low kVp during fast kVp switching using the captured incident spectra, scan a water phantom and normalize the computed detector coefficients to water, adjust the computed effective X-ray incident spectra based on the normalized detector coefficients, compute basis material decomposition functions using the adjusted X-ray incident spectra, and generate one or more basis material density images using the computed basis material decomposition functions.
摘要翻译：成像系统包括：x射线源，其朝向物体发射X射线束;接收被物体衰减的高频电磁能的检测器;可操作地连接到检测器的数据采集系统（DAS）;以及计算机可操作地连接到DAS。计算机被编程为基于静态低kVp测量和静态高kVp测量来计算检测器系数，在快速kVp切换期间在高和低kVp处捕获入射光谱，在快速kVp期间计算高和低kVp处的有效X射线入射光谱使用捕获的入射光谱切换，扫描水体模型并将计算的检测器系数归一化为水，基于归一化的检测器系数调整计算的有效X射线入射光谱，使用调整的X射线入射光谱计算基础材料分解函数，并使用所计算的基础材料分解函数生成一个或多个基础材料密度图像。

9. 发明授权

US08363917B2 System and method of image artifact reduction in fast kVp switching CT 有权
标题翻译：快速kVp开关CT中图像伪影减少的系统和方法
公开(公告)号：US08363917B2
公开(公告)日：2013-01-29
申请号：US12578886
申请日：2009-10-14
申请人： Jiahua Fan , Naveen Chandra , Andrew Johnson , Jiang Hsieh , Fang Dong , Mary Sue Kulpins , Peter Crandall
发明人： Jiahua Fan , Naveen Chandra , Andrew Johnson , Jiang Hsieh , Fang Dong , Mary Sue Kulpins , Peter Crandall
IPC分类号： G06K9/00 , A61B6/00 , H05G1/64
CPC分类号： G06T11/008 , G06T2211/408
摘要： A CT system includes a generator configured to energize an x-ray source to a first kilovoltage (kVp) and to a second kVp, and a computer that is programmed to acquire a first view dataset with the x-ray source energized to the first kVp and a second view dataset with the x-ray source energized to the second kVp, generate a base correction image using the first view dataset and the second view dataset, and reconstruct a pair of base material images from the first view dataset and from the second view dataset. The computer is also programmed to estimate artifact correlation in the pair of base material images using the base correction image, generate a pair of final base material images and a final monochromatic image, and correct one of the pair of final base material images and the final monochromatic image at a keV value using the estimated artifact correlation.
摘要翻译： CT系统包括发电机，其被配置为将x射线源激励到第一千伏（kVp）和第二kVp;以及计算机，其被编程为获取第一视图数据集，其中x射线源被激励到第一kVp 以及将x射线源激励到第二kVp的第二视图数据集，使用第一视图数据集和第二视图数据集生成基本校正图像，并且从第一视图数据集和第二视图数据集重构一对基本材料图像查看数据集。计算机还被编程为使用基本校正图像来估计一对基础材料图像中的伪像相关性，生成一对最终的基底图像和最终的单色图像，并且校正一对最终基底图像和最终的基底图像中的一个使用估计的伪像相关性，以keV值的单色图像。

10. 发明授权

US08199874B2 System and method of mitigating low signal data for dual energy CT 有权
标题翻译：减轻双能量CT的低信号数据的系统和方法
公开(公告)号：US08199874B2
公开(公告)日：2012-06-12
申请号：US12635901
申请日：2009-12-11
申请人： Thomas L. Toth , Jiang Hsieh , Naveen Chandra , Xiaoye Wu
发明人： Thomas L. Toth , Jiang Hsieh , Naveen Chandra , Xiaoye Wu
IPC分类号： A61B6/00 , H05G1/64
CPC分类号： A61B6/405 , A61B6/032 , A61B6/4035 , A61B6/4241 , A61B6/4266 , A61B6/4411 , A61B6/482 , G01T1/2985 , G06T11/005 , G06T2211/408
摘要： A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to obtain kVp projection data at a first kVp, obtain kVp projection data at a second kVp, extract data from the kVp projection data obtained at the second kVp, add the extracted data to the kVp projection data obtained at the first kVp to generate mitigated projection data at the first kVp, and generate an image using the mitigated projection data at the first kVp and using the projection data obtained at the second kVp.
摘要翻译： CT系统包括具有用于接收待扫描物体的开口的可旋转机架，以及控制器，被配置为在第一kVp处获得kVp投影数据，在第二kVp处获得kVp投影数据，从在第二kVp，将提取的数据加到在第一kVp处获得的kVp投影数据，以在第一kVp处产生减轻的投影数据，并使用第一kVp处的减轻投影数据并使用在第二kVp获得的投影数据生成图像 kVp。

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