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1. 发明授权

US09008269B2 Method and apparatus for adjusting a field of view for exposure of an X-ray system, and an X-ray system 有权
标题翻译：用于调整用于X射线系统的曝光的视野的方法和装置以及X射线系统
公开(公告)号：US09008269B2
公开(公告)日：2015-04-14
申请号：US13598643
申请日：2012-08-30
申请人： Jian Wang , Bin Ye , Yannan Huang , Yonghui Han
发明人： Jian Wang , Bin Ye , Yannan Huang , Yonghui Han
IPC分类号： A61B6/08 , A61B6/00 , A61B6/06
CPC分类号： A61B6/52 , A61B6/06 , A61B6/08 , A61B6/4021 , A61B6/469 , A61B6/548
摘要： A method for adjusting a field of view for exposure of an X-ray system is provided. The method comprises: capturing an image of a patient on an examining table of the system by an image sensor, wherein the image sensor is placed at a predetermined position in the system; displaying the captured image on a display for selection of a region of interest or a point of interest by a user on the image; automatically determining a target position of an X-ray source in response to the selection of the region of interest or the point of interest on the image, wherein a desired field of view for exposure covering the region of interest or the point of interest is obtained when the X-ray source is located at the target position; and automatically locating the X-ray source at the target position in response to the determination of the target position.
摘要翻译：提供了一种用于调整用于X射线系统的曝光的视场的方法。该方法包括：通过图像传感器在系统的检查表上捕获患者的图像，其中图像传感器被放置在系统中的预定位置; 在显示器上显示所捕获的图像，以便在图像上选择用户感兴趣的区域或兴趣点; 响应于对图像上的感兴趣区域或兴趣点的选择，自动确定X射线源的目标位置，其中获得覆盖感兴趣区域或感兴趣点的曝光的期望视场当X射线源位于目标位置时; 并且响应于目标位置的确定，将X射线源自动定位在目标位置。

2. 发明授权

US07737145B2 Diamine derivatives as inhibitors of leukotriene A4 hydrolase 有权
标题翻译：二胺衍生物作为白三烯A4水解酶的抑制剂
公开(公告)号：US07737145B2
公开(公告)日：2010-06-15
申请号：US11644244
申请日：2006-12-22
申请人： Damian Arnaiz , Greg Brown , Emmanuel Claret , Arwed Cleve , David Davey , William Guilford , Seock-Kyu Khim , Thomas Kirkland , Monica J. Kochanny , Amy Liang , David Light , John Parkinson , David Vogel , Guo Ping Wei , Bin Ye
发明人： Damian Arnaiz , Greg Brown , Emmanuel Claret , Arwed Cleve , David Davey , William Guilford , Seock-Kyu Khim , Thomas Kirkland , Monica J. Kochanny , Amy Liang , David Light , John Parkinson , David Vogel , Guo Ping Wei , Bin Ye
IPC分类号： A01N43/60 , A61K31/495 , C07D241/36 , C07D271/00 , C07D487/00 , C07D491/00 , C07D495/00 , C07D497/00 , C07D498/00 , C07D513/00
CPC分类号： C07D487/08 , C07B2200/07 , C07C217/58 , C07C229/08 , C07C229/38 , C07C233/78 , C07C255/57 , C07C271/20 , C07C2601/14 , C07D207/04 , C07D207/09 , C07D207/16 , C07D211/26 , C07D211/34 , C07D211/58 , C07D243/08 , C07D263/14 , C07D263/32 , C07D277/22 , C07D277/68 , C07D295/04 , C07D295/096 , C07D295/16 , C07D401/10 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D451/02 , C07D451/04
摘要： This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
摘要翻译：本发明涉及式（I）化合物：其中r，q，R，R2，R3，R4，R5a，R5b，R5c，R6a，R6b，R6c，R7，R8和R9在本文中描述为单立体异构体或作为立体异构体或其药学上可接受的盐，溶剂合物，包合物，多晶型物，铵离子，N-氧化物或前药的混合物; 其是白三烯A4水解酶抑制剂，因此可用于治疗炎症性疾病。还公开了包含本发明化合物的药物组合物和制备本发明化合物的方法。

3. 发明申请

US20080176833A1 DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS 有权
标题翻译：作为蛋白激酶抑制剂有用的二氢吡啶衍生物
公开(公告)号：US20080176833A1
公开(公告)日：2008-07-24
申请号：US11955777
申请日：2007-12-13
申请人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
发明人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
IPC分类号： A61K31/55 , C07D213/02 , A61K31/4427 , C07D455/02 , A61K31/4375 , C07D295/00 , A61K31/5377 , A61P35/00 , C07D239/24 , A61K31/506 , C07D221/00 , A61K31/496 , C07D223/02
CPC分类号： C07D401/04 , C07D211/90 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/14 , C07D471/04
摘要： This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.
摘要翻译：本发明提供具有蛋白酪氨酸激酶抑制活性的新颖的具有蛋白酪氨酸激酶抑制活性的二氢吡啶衍生物，其制备方法及其用于治疗c-Met介导的疾病或c-Met介导的病症的用途。

4. 发明申请

US20070155727A1 Amide inhibitors of leukotriene A4 hydrolase 审中-公开
标题翻译：白三烯A4水解酶的酰胺抑制剂
公开(公告)号：US20070155727A1
公开(公告)日：2007-07-05
申请号：US11644822
申请日：2006-12-22
申请人： Ming Chen , Emmanuel Claret , Arwed Cleve , David Davey , William Guilford , Seock-Kyu Khim , Thomas Kirkland , Monica Kochanny , Amy Liang , David Light , John Parkinson , David Vogel , Guo Wei , Bin Ye , Hong Ye
发明人： Ming Chen , Emmanuel Claret , Arwed Cleve , David Davey , William Guilford , Seock-Kyu Khim , Thomas Kirkland , Monica Kochanny , Amy Liang , David Light , John Parkinson , David Vogel , Guo Wei , Bin Ye , Hong Ye
IPC分类号： A61K31/551 , A61K31/407 , C07D487/02 , C07D243/08
CPC分类号： C07D207/04 , C07C237/04 , C07C237/06 , C07C237/30 , C07C255/58 , C07C275/40 , C07C275/42 , C07C275/62 , C07C311/05 , C07C311/08 , C07C311/09 , C07C311/37 , C07C2601/08 , C07C2601/14 , C07D211/06 , C07D243/08 , C07D295/04 , C07D295/16 , C07D487/02 , C07D487/08
摘要： This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4a, R4b, R4c, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, R9 and R10 are described herein, or pharmaceutically acceptable salts, solvates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and which are therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of using and preparing the compounds of the invention are also disclosed.
摘要翻译：本发明涉及式（I）化合物：其中r，q，R，R 2，R 3，R 4a，R 4， R 4b，R 4c，R 5a，R 5b，R 5c，R 5，R 5， R 6b，R 6b，R 6，R 7，R 8，R 8，R 8，本文描述了本发明的其它药学上可接受的盐，溶剂合物，多晶型物，铵离子，N-氧化物或前体药物; 其是白三烯A 4水解酶抑制剂，因此其可用于治疗炎症性疾病。还公开了包含本发明化合物的药物组合物和使用和制备本发明化合物的方法。

5. 发明授权

US06864368B2 N-heterocyclic derivatives as NOS inhibitors 失效
公开(公告)号：US06864368B2
公开(公告)日：2005-03-08
申请号：US10122006
申请日：2002-04-12
申请人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
发明人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
IPC分类号： C07D403/14 , A61K31/506 , A61K31/5377 , A61K31/547 , A61P1/04 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/08 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07D213/00 , C07D233/00 , C07D239/00 , C07D241/02 , C07D265/00 , C07D279/00 , C07D317/44 , C07D319/00 , C07D333/02 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.

6. 发明授权

US06864263B2 N-heterocyclic derivatives as NOS inhibitors 失效
公开(公告)号：US06864263B2
公开(公告)日：2005-03-08
申请号：US10121659
申请日：2002-04-12
申请人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
发明人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
IPC分类号： C07D403/14 , A61K31/506 , A61K31/5377 , A61K31/547 , A61P1/04 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/08 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07D213/00 , C07D233/00 , C07D239/00 , C07D241/02 , C07D265/00 , C07D279/00 , C07D317/44 , C07D319/00 , C07D333/02 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.

7. 发明授权

US6140351A Ortho-anthranilamide derivatives as anti-coagulants 失效
标题翻译：邻氨基苯甲酰胺衍生物作为抗凝剂
公开(公告)号：US6140351A
公开(公告)日：2000-10-31
申请号：US187459
申请日：1998-11-05
申请人： Damian O. Arnaiz , Yuo-Ling Chou , Brian D. Griedel , Rushad E. Karanjawala , Monica J. Kochanny , Wheeseong Lee , Amy Mei Liang , Michael M. Morrissey , Gary B. Phillips , Karna Lyn Sacchi , Steven T. Sakata , Kenneth J. Shaw , R. Michael Snider , Shung C. Wu , Bin Ye , Zuchun Zhao
发明人： Damian O. Arnaiz , Yuo-Ling Chou , Brian D. Griedel , Rushad E. Karanjawala , Monica J. Kochanny , Wheeseong Lee , Amy Mei Liang , Michael M. Morrissey , Gary B. Phillips , Karna Lyn Sacchi , Steven T. Sakata , Kenneth J. Shaw , R. Michael Snider , Shung C. Wu , Bin Ye , Zuchun Zhao
IPC分类号： C07D333/38 , C07D333/70 , C07D401/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D473/06 , C07D473/34 , A61K31/44 , C07D409/00 , C07D411/00
CPC分类号： C07D401/04 , C07D333/38 , C07D333/70 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D473/06 , C07D473/34
摘要： This invention is directed to compounds of formula (III): ##STR1## wherein B, C, D, E, R.sup.1, R.sup.2 and R.sup.3 are disclosed herein. These compounds are disclosed as being useful as anti-coagulants.
摘要翻译：本发明涉及式（III）化合物：其中B，C，D，E，R 1，R 2和R 3在本文中公开。这些化合物被公开用作抗凝剂。

8. 发明申请

US20150364122A1 Music Note Indicating Method And System For Electronic Piano, Mobile Terminal And Electronic Piano 审中-公开
标题翻译：音乐笔记电子钢琴，手机终端和电子钢琴指示方法及系统
公开(公告)号：US20150364122A1
公开(公告)日：2015-12-17
申请号：US14729305
申请日：2015-06-03
申请人： Bin Ye
发明人： Bin Ye
IPC分类号： G10H1/00 , G10C5/00
CPC分类号： G10H1/0016 , G10G1/02 , G10H2220/061 , G10H2220/441 , G10H2240/251
摘要： Provided is a music note indicating method for an electronic piano, a mobile terminal, an electronic piano and a music note indicating system. The electronic piano includes a keyboard with a plurality of keys, a controlling device and a plurality of LED indicating lamps. The plurality of LED indicating lamps are located in a plane parallel to the keyboard. The method includes: obtaining a music score information of a predetermined music score by a mobile terminal; analyzing the music score information to generate a music note sequence comprising at least one first music note data by the mobile terminal; generating a control signal according to the at least one first music note data and sending the control signal to the controlling device by the mobile terminal; and controlling the plurality of LED indicating lamps to indicate the music note sequence according to the control signal by the controlling device.
摘要翻译：提供了一种用于电子钢琴，移动终端，电子钢琴和音乐笔记指示系统的音乐笔记指示方法。电子钢琴包括具有多个键的键盘，控制装置和多个LED指示灯。多个LED指示灯位于与键盘平行的平面中。该方法包括：通过移动终端获得预定乐谱的乐谱信息; 分析音乐乐谱信息以生成由移动终端包括至少一个第一音乐数据的音乐音符序列; 根据所述至少一个第一音乐音符数据生成控制信号，并由所述移动终端向控制设备发送控制信号; 以及根据控制装置的控制信号，控制多个LED指示灯来指示音乐音符序列。

9. 发明申请

US20110045508A1 Urinary CA125 Peptides as Biomarkers of Ovarian Cancer 有权
标题翻译：尿CA125肽作为卵巢癌生物标志物
公开(公告)号：US20110045508A1
公开(公告)日：2011-02-24
申请号：US12865508
申请日：2009-01-30
申请人： Bin Ye , Daniel Cramer
发明人： Bin Ye , Daniel Cramer
IPC分类号： G01N33/68 , C12P21/00
CPC分类号： G01N33/57449 , C07K14/4748
摘要： The present invention is directed to diagnostic methods based upon the detection of peptides derived from the degradation of CA125. In particular, it is concerned with assays of urine samples collected from women for the purpose of determining whether they are at increased risk for having ovarian cancer, have decreased their risk as the result of clinical or non-clinical procedures, to monitor the efficacy of a treatment method, or to determine whether cancer has recurred or advanced.
摘要翻译：本发明涉及基于检测衍生自CA125降解的肽的诊断方法。特别地，它涉及从妇女收集的尿液样品的测定，以确定它们是否具有增加的患有卵巢癌的风险，降低其作为临床或非临床程序的结果的风险，以监测其功效治疗方法，或确定癌症是否复发或进展。

10. 发明申请

US20080159485A1 RADIOGRAPHIC SYSTEM 失效
标题翻译：放射学系统
公开(公告)号：US20080159485A1
公开(公告)日：2008-07-03
申请号：US11966579
申请日：2007-12-28
申请人： Bin Ye
发明人： Bin Ye
IPC分类号： G03B42/04
CPC分类号： G03B42/04
摘要： A radiographic system(100) is provided wherein a single X-ray detector can be handled freely using a cable and which can prevent an operator or a patient from being troubled by the cable. The radiographic system(100) comprises a radiographic panel(5) configured to radiograph in two dimensions a radiation exposed to a subject and output radiation image data, a cable(6) for the supply of electric power to the radiographic panel and transfer of the radiation image data, a conveyance unit(8) for conveying the cable in a predetermined direction, a cable length adjusting unit(7) provided in the conveyance unit to adjust the length of the cable, and a movement control unit(72) configured to move the conveyance unit in accordance with a tilting direction of the cable from the cable length adjusting unit to the radiographic panel.
摘要翻译：提供了一种放射线照相系统（100），其中可以使用电缆自由地处理单个X射线检测器，并且可以防止操作者或患者受到电缆的困扰。射线照相系统（100）包括放射线照相面板（5），其配置成二维放射照射暴露于对象的辐射并输出放射线图像数据;电缆（6），用于向射线照相面板供应电力并传送辐射图像数据，用于沿预定方向传送电缆的传送单元（8），设置在传送单元中以调节电缆长度的电缆长度调节单元（7），以及移动控制单元（72）将输送单元按照电缆从电缆长度调节单元的倾斜方向移动到射线照相面板。

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