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1. 发明申请

US20130012988A1 Wound Closure Material 审中-公开
标题翻译：伤口闭合材料
公开(公告)号：US20130012988A1
公开(公告)日：2013-01-10
申请号：US13574309
申请日：2011-01-18
申请人： Jessica Blume , Andreas Dobmann , Willi Schwotzer
发明人： Jessica Blume , Andreas Dobmann , Willi Schwotzer
IPC分类号： A61B17/03
CPC分类号： A61F15/006 , A61B17/085 , A61L15/425
摘要： The invention relates to a wound closure material with a core of biodegradable material, wherein at least one side, preferably two sides of the core of biodegradable material are provided with at least one, preferably a multitude of discrete spots of an adhesive. As with more common wound closure techniques like sutures, clips and tapes applied over the wound, new tissue has to close a gap between the wound edges. Use of a wound closing material of the present invention does not only have the advantage of a secure physical connection between the edges, but the material serves as scaffolding for the new tissue. It may also serve the cells as artificial extracellular matrix they can adhere to.
摘要翻译：本发明涉及一种具有可生物降解材料芯的伤口闭合材料，其中可生物降解材料芯的至少一侧，优选两侧具有至少一个，优选多个离散的粘合剂点。与更常见的伤口闭合技术一样，例如缝合线，夹子和带施加在伤口上，新组织必须封闭伤口边缘之间的间隙。使用本发明的伤口闭合材料不仅具有边缘之间安全的物理连接的优点，而且该材料用作新组织的脚手架。它也可以将细胞作为可以附着的人造细胞外基质来服用。

2. 发明申请

US20130288034A1 Resorbable Membrane 审中-公开
标题翻译：可再吸收膜
公开(公告)号：US20130288034A1
公开(公告)日：2013-10-31
申请号：US13880920
申请日：2011-11-07
申请人： Jessica Blume , Stephan Buser , Andreas Dobmann , Erika Zimmermann
发明人： Jessica Blume , Stephan Buser , Andreas Dobmann , Erika Zimmermann
IPC分类号： A61L15/64
CPC分类号： A61L15/64 , A61L15/26 , A61L31/06 , A61L31/148 , C08L75/04
摘要： The present invention relates to resorbable membranes for medical uses. The membranes according to the present invention are produced or producible from a composition comprising at least one polyol component, at least one polyisocyanate component and an additive selected from polyvinylpyrrolidone, polyvinylpolypyrrolidone, a copolymer of polyvinylpyrrolidone with vinylacetate, vinylimidazole or vinylcaprolactam or mixtures thereof. The present invention further relates to a kit comprising a multitude of membranes with different absorption rates.
摘要翻译：本发明涉及用于医疗用途的可吸收膜。根据本发明的膜由包含至少一种多元醇组分，至少一种多异氰酸酯组分和选自聚乙烯吡咯烷酮，聚乙烯吡咯烷酮，聚乙烯吡咯烷酮与乙酸乙烯酯的共聚物，乙烯基咪唑或乙烯基己内酰胺或其混合物的添加剂组成的组合物生产或生产。本发明还涉及包含具有不同吸收速率的多种膜的试剂盒。

3. 发明申请

US20120136081A1 Resorbable Polyurethane Wound Cover 审中-公开
标题翻译：可再吸收的聚氨酯伤口罩
公开(公告)号：US20120136081A1
公开(公告)日：2012-05-31
申请号：US13388188
申请日：2010-08-03
申请人： Jessica Blume , Stephan Buser , Andreas Dobmann , Erika Zimmermann
发明人： Jessica Blume , Stephan Buser , Andreas Dobmann , Erika Zimmermann
IPC分类号： A61L15/42 , C08J9/04
CPC分类号： A61L15/42 , A61L15/425 , A61L15/60 , C08L75/04
摘要： The present invention relates to a biocompatible, resorbable polyurethane foam wound cover with open pores and an adjustable resorption rate having improved properties when used on skin or connective tissue wounds as well as a method of production of such a polyurethane foam wound cover.
摘要翻译：本发明涉及具有开放孔的生物相容性可再吸收的聚氨酯泡沫塑料卷绕盖，以及当用于皮肤或结缔组织伤口时具有改进性能的可调吸收率以及这种聚氨酯泡沫伤口盖的生产方法。

4. 发明申请

US20080107718A1 Wound Covering and Production Process 有权
标题翻译：伤口覆盖和生产过程
公开(公告)号：US20080107718A1
公开(公告)日：2008-05-08
申请号：US11928364
申请日：2007-10-30
申请人： Catherine Baron , Alfred Rasche , Fabian Leuthard , Adrian Schulthess , Andreas Dobmann , Manuel Leumann , Dirk Clasen
发明人： Catherine Baron , Alfred Rasche , Fabian Leuthard , Adrian Schulthess , Andreas Dobmann , Manuel Leumann , Dirk Clasen
IPC分类号： A61F13/02
CPC分类号： A61F13/0256 , A61F13/0209 , A61F13/0226 , A61F13/0253 , Y10T156/1062
摘要： The invention relates to a production process for a foam wound dressing having an external germ barrier, more particularly a film layer, and also to a wound dressing thus obtained, having, where appropriate, a pressure-sensitive adhesive layer. In the process according to the invention the germ barrier is produced by means of extrusion directly on the foam base. This results in a more reliable bond between foam layer and germ barrier, without detriment to the absorptiveness of the foam for wound exudate. The process presented is simple and cost-effective, and all of the requirements from the medical sector (e.g. absence of solvent) can be met.
摘要翻译：本发明涉及一种泡沫伤口敷料的制造方法，其具有外部细菌屏障，特别是膜层，并且还涉及如此得到的伤口敷料，其中适当地具有压敏粘合剂层。在根据本发明的方法中，通过直接在泡沫基底上挤出生产细菌屏障。这导致泡沫层和胚芽屏障之间的更可靠的结合，而不损害泡沫用于伤口渗出物的吸收性。所呈现的过程是简单和成本有效的，并且可以满足来自医疗部门的所有要求（例如不存在溶剂）。

5. 发明申请

US20100222730A1 Wound Covering and its Method of Production by Extrusion Coating 失效
标题翻译：伤口覆盖及其挤压成型方法
公开(公告)号：US20100222730A1
公开(公告)日：2010-09-02
申请号：US12161713
申请日：2006-10-27
申请人： Manuel Leumann , Andreas Dobmann
发明人： Manuel Leumann , Andreas Dobmann
IPC分类号： A61L15/22 , B29C47/06
CPC分类号： B32B37/153 , A61L15/26 , A61L15/425 , B29C47/0019 , B29C47/0021 , B29C47/0047 , B29C47/025 , B29C47/065 , B29K2075/00 , B29L2031/753 , B32B5/18 , B32B5/20 , B32B27/065 , B32B27/08 , B32B27/285 , B32B27/40 , B32B2037/0092 , B32B2038/0084 , B32B2266/0278 , B32B2266/06 , B32B2305/022 , B32B2307/728 , B32B2535/00 , C08L75/04
摘要： The invention relates to a production method for a foam wound dressing with an outer germ barrier, in particular a film layer, and to a wound dressing obtained by such a method. In the method according to the invention, the germ barrier is generated by means of extrusion directly on the foam support. This results in a more reliable union between foam layer and germ barrier, without thereby compromising the absorbency of the foam in respect of wound exudate. The proposed method is simple and inexpensive and is able to satisfy all the requirements of the medical sector (e.g. freedom from solvents).
摘要翻译：本发明涉及具有外胚层屏障，特别是膜层的泡沫伤口敷料以及通过这种方法获得的伤口敷料的制造方法。在根据本发明的方法中，通过直接在泡沫支撑体上挤出产生菌丝屏障。这导致泡沫层和胚芽屏障之间的更可靠的联合，而不会因此损害泡沫在伤口渗出物上的吸收性。所提出的方法简单和便宜，并且能够满足医疗部门的所有要求（例如不溶于溶剂）。

6. 发明申请

US20080051485A1 Hot-Melt Composition Comprising Hydrocolloids 有权
标题翻译：包含水胶体的热熔体组合物
公开(公告)号：US20080051485A1
公开(公告)日：2008-02-28
申请号：US11572167
申请日：2005-06-22
申请人： Pia Frei , Andreas Dobmann , Judith Nyffeler
发明人： Pia Frei , Andreas Dobmann , Judith Nyffeler
IPC分类号： A61L15/58 , A61L15/60
CPC分类号： A61L15/58 , A61L15/60
摘要： The invention relates to a hot-melt composition, especially for using as an absorbent medical or cosmetic article, preferably as a wound dressing, and containing (a) a chemically cross-linked polymer matrix, and (b) hydrocolloids which are embedded in the chemically cross-linked polymer matrix. The inventive composition can be obtained by processing a melt in a hot melt method, said melt having a melting viscosity of less than 100 Pa*s, preferably less than 75 Pa*s, and especially preferably less than 50 Pa*s, at a processing temperature of less than 150° C., preferably less than 140° C., and especially preferably less than 130° C.
摘要翻译：本发明涉及一种热熔组合物，特别是用作吸收性药物或化妆品，优选作为伤口敷料，并且包含（a）化学交联的聚合物基质，和（b）嵌入在所述组合物中的水胶体化学交联的聚合物基质。本发明的组合物可以通过以热熔方法加工熔体而获得，所述熔体的熔融粘度小于100Pa·s，优选小于75Pa·s，特别优选小于50Pa·s，处理温度小于150℃，优选小于140℃，特别优选小于130℃。

7. 发明申请

US20070054088A1 UV-Cured Hot-Melt Adhesive 审中-公开
标题翻译：紫外线固化热熔胶
公开(公告)号：US20070054088A1
公开(公告)日：2007-03-08
申请号：US10547765
申请日：2004-03-01
申请人： Christelle Matijasic , Pia Frei , Andreas Dobmann
发明人： Christelle Matijasic , Pia Frei , Andreas Dobmann
IPC分类号： B32B3/04
CPC分类号： C09J133/06 , C08L75/16 , C08L2666/20 , C09J7/385 , Y10T428/24207
摘要： The inventive composition contains at least one polyacrylate that can be melted and cross-linked using UV light, optional additives and is characterised by an oligomer compound comprising at least one functional group that can be cross-linked using UV, said compound having a viscosity of between 0.1 and 20 Pa·s at 25° C. The invention also relates to the use of the composition as a UV cross-linked hot-melt adhesive and to a method for producing a substrate that is provided with the composition. The composition can be used at a lower temperature than previous conventional hot-melt adhesives.
摘要翻译：本发明的组合物含有至少一种聚丙烯酸酯，其可以使用UV光，任选的添加剂进行熔融和交联，并且其特征在于包含至少一个可以使用UV交联的官能团的低聚物化合物，所述化合物的粘度为在25℃下为0.1至20Pa.s。本发明还涉及该组合物作为UV交联热熔粘合剂的用途以及提供该组合物的制备基材的方法。组合物可以在比以前的常规热熔粘合剂更低的温度下使用。

8. 发明申请

US20060211808A1 Adhesive composition 审中-公开
标题翻译：粘合剂组合物
公开(公告)号：US20060211808A1
公开(公告)日：2006-09-21
申请号：US10563149
申请日：2004-05-08
申请人： Pia Frei , Andreas Dobmann
发明人： Pia Frei , Andreas Dobmann
IPC分类号： C09B67/00
CPC分类号： C09J167/00 , C08K5/0016 , C08L53/02 , C08L67/00 , C08L2201/00 , C08L2666/02 , C08L2666/18 , C08L2666/24 , C09J153/02
摘要： The invention relates to an adhesive composition containing (a) an elastomer block copolymer having a diblock portion greater than 40%, preferably greater than 55%, more preferably greater than 70%, (b) a sulphonated, especially branched copolyester and (c) optionally, additional additives, such as tackifiers and/or softeners and/or stabilisers. The inventive adhesive compositions have advantages, particularly, based on high wet-peel strength.
摘要翻译：本发明涉及一种粘合剂组合物，其包含（a）二嵌段部分大于40％，优选大于55％，更优选大于70％的弹性体嵌段共聚物，（b）磺化的，特别是支链的共聚酯和（c）任选地，其它添加剂，例如增粘剂和/或软化剂和/或稳定剂。本发明的粘合剂组合物具有优点，特别是基于高湿剥离强度。

9. 发明授权

US09012529B2 Hot-melt composition comprising hydrocolloids 有权
标题翻译：包含水胶体的热熔组合物
公开(公告)号：US09012529B2
公开(公告)日：2015-04-21
申请号：US11572167
申请日：2005-06-22
申请人： Pia Frei , Andreas Dobmann , Judith Nyffeler
发明人： Pia Frei , Andreas Dobmann , Judith Nyffeler
IPC分类号： B29C71/04 , A61F15/00 , A61L15/58 , A61L15/60
CPC分类号： A61L15/58 , A61L15/60
摘要： A hot-melt formulation useful as a wound dressing comprises a chemically crosslinked polymer matrix obtainable from prepolymers crosslinkable by means of photopolymerization. Hydrocolloids are embedded in the chemically crosslinked polymer, matrix. The formulation is obtainable by combining the prepolymers and hydrocolloids, and heating and processing the mixture through a slot die, wherein the mixture has a viscosity of less than 100 Pa*s and a processing temperature of less than 150° C. The prepolymers are crosslinked by means of photopolymerization by irradiation with UV light.
摘要翻译：可用作伤口敷料的热熔制品包括可通过光聚合可交联的预聚物获得的化学交联聚合物基质。水胶体包埋在化学交联的聚合物基质中。通过组合预聚物和水胶体，以及通过狭槽模头加热和处理混合物可获得该配方，其中该混合物的粘度小于100Pa·s，加工温度低于150℃。预聚物交联通过用UV光照射进行光聚合。

10. 发明授权

US08242325B2 Wound covering and its method of production by extrusion coating 失效
标题翻译：绕线覆盖及其挤压成型方法
公开(公告)号：US08242325B2
公开(公告)日：2012-08-14
申请号：US12161713
申请日：2006-10-27
申请人： Manuel Leumann , Andreas Dobmann
发明人： Manuel Leumann , Andreas Dobmann
IPC分类号： A61F13/00 , B29D7/00 , B32B33/00
CPC分类号： B32B37/153 , A61L15/26 , A61L15/425 , B29C47/0019 , B29C47/0021 , B29C47/0047 , B29C47/025 , B29C47/065 , B29K2075/00 , B29L2031/753 , B32B5/18 , B32B5/20 , B32B27/065 , B32B27/08 , B32B27/285 , B32B27/40 , B32B2037/0092 , B32B2038/0084 , B32B2266/0278 , B32B2266/06 , B32B2305/022 , B32B2307/728 , B32B2535/00 , C08L75/04
摘要： The invention relates to a production method for a foam wound dressing with an outer germ barrier, in particular a film layer, and to a wound dressing obtained by such a method. In the method according to the invention, the germ barrier is generated by means of extrusion directly on the foam support. This results in a more reliable union between foam layer and germ barrier, without thereby compromising the absorbency of the foam in respect of wound exudate. The proposed method is simple and inexpensive and is able to satisfy all the requirements of the medical sector (e.g. freedom from solvents).
摘要翻译：本发明涉及具有外胚层屏障，特别是膜层的泡沫伤口敷料以及通过这种方法获得的伤口敷料的制造方法。在根据本发明的方法中，通过直接在泡沫支撑体上挤出产生菌丝屏障。这导致泡沫层和胚芽屏障之间的更可靠的联合，而不会因此损害泡沫在伤口渗出物上的吸收性。所提出的方法简单和便宜，并且能够满足医疗部门的所有要求（例如不溶于溶剂）。

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