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1. 发明授权

US08444802B2 Catheter having a readily bondable multilayer soft tip 有权
公开(公告)号：US08444802B2
公开(公告)日：2013-05-21
申请号：US12468745
申请日：2009-05-19
申请人： Jeong S. Lee , Kenneth L. Wantink
发明人： Jeong S. Lee , Kenneth L. Wantink
IPC分类号： B32B37/00 , B29C65/00 , A61M25/00
CPC分类号： A61M25/008 , A61M25/001 , A61M25/0045 , A61M25/0068 , A61M25/0069 , A61M25/10 , A61M25/1025 , A61M25/104 , A61M2025/0047 , A61M2025/0081 , A61M2025/1093 , Y10T156/1005
摘要： A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon.

2. 发明授权

US06991626B2 Polymer jacket with adhesive inner layer 失效
公开(公告)号：US06991626B2
公开(公告)日：2006-01-31
申请号：US10264855
申请日：2002-10-04
申请人： Kenneth L. Wantink , Jeong S. Lee , Emmanuel C. Biagtan , Alan A. Tannier
发明人： Kenneth L. Wantink , Jeong S. Lee , Emmanuel C. Biagtan , Alan A. Tannier
IPC分类号： A61M25/00
CPC分类号： A61M25/104 , A61M25/007 , A61M25/0075 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/1079 , A61M2025/1093
摘要： The invention is an elongate intracorporeal member having a polymer jacket secured to a high strength shaft with the polymer jacket having an outer layer of polymeric material and an inner layer formed of polymeric adhesive. In one embodiment, a balloon catheter has a proximal high strength tubular section with a polymer jacket having an polymeric outer layer and an adhesive polymer inner layer. In another embodiment, a guidewire has an elongate core with polymer jacket disposed about at least a portion of the elongate core, wherein the polymer jacket comprises a polymeric outer layer an inner layer of polymeric adhesive disposed between and bonding the outer layer to the elongate core.

3. 发明授权

US07037291B2 Catheter shaft junction having a polymeric reinforcing member with a high glass transition temperature 有权
公开(公告)号：US07037291B2
公开(公告)日：2006-05-02
申请号：US10010212
申请日：2001-12-04
申请人： Jeong S. Lee , Kenneth L. Wantink
发明人： Jeong S. Lee , Kenneth L. Wantink
IPC分类号： A61M29/00
CPC分类号： A61M25/1036 , A61M2025/0034 , A61M2025/0037
摘要： A catheter having a polymeric reinforcing member at a junction between shaft sections such as a rapid exchange catheter junction. The polymeric reinforcing member is around or within the tubular member defining the inflation lumen or the tubular member defining the guidewire lumen at the rapid exchange junction to prevent or inhibit damage to the tubular members defining the inflation lumen and/or guidewire lumen during assembly or use of a balloon catheter. In one embodiment, the polymeric reinforcing member is formed of a first polymeric material having a glass transition temperature greater than a glass transition temperature of a second polymeric material forming the distal portion of the proximal tubular member or the proximal portion of the inner tubular member. The first polymeric material forming the polymeric reinforcing member is preferably a high temperature, high modulus material, such as polyimide, and most preferably a thermoset polyimide.

4. 发明授权

US06488655B1 Polymer jacket with adhesive inner layer 有权
标题翻译：聚合物护套与粘合剂内层
公开(公告)号：US06488655B1
公开(公告)日：2002-12-03
申请号：US09739180
申请日：2000-12-15
申请人： Kenneth L. Wantink , Jeong S. Lee , Emmanuel C. Biagtan , Alan A. Tannier
发明人： Kenneth L. Wantink , Jeong S. Lee , Emmanuel C. Biagtan , Alan A. Tannier
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/007 , A61M25/0075 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/1079 , A61M2025/1093
摘要： The invention is an elongate intracorporeal member having a polymer jacket secured to a high strength shaft with the polymer jacket having an outer layer of polymeric material and an inner layer formed of polymeric adhesive. In one embodiment, a balloon catheter has a proximal high strength tubular section with a polymer jacket having an polymeric outer layer and an adhesive polymer inner layer. In another embodiment, a guidewire has an elongate core with polymer jacket disposed about at least a portion of the elongate core, wherein the polymer jacket comprises a polymeric outer layer an inner layer of polymeric adhesive disposed between and bonding the outer layer to the elongate core.
摘要翻译：本发明是具有固定到高强度轴的聚合物护套的细长的体内构件，聚合物护套具有聚合物材料的外层和由聚合物粘合剂形成的内层。在一个实施例中，球囊导管具有近端高强度管状部分，聚合物护套具有聚合物外层和粘合聚合物内层。在另一个实施例中，导丝具有细长芯，其中聚合物护套设置在细长芯的至少一部分周围，其中聚合物护套包括聚合物外层，聚合物粘合剂的内层设置在外层与细长芯之间。

5. 发明申请

US20080262470A1 CATHETER HAVING A READILY BONDABLE MULTILAYER SOFT TIP 有权
标题翻译：具有可自由粘合的多层柔性提示的导管
公开(公告)号：US20080262470A1
公开(公告)日：2008-10-23
申请号：US11738260
申请日：2007-04-20
申请人： Jeong S. Lee , Kenneth L. Wantink
发明人： Jeong S. Lee , Kenneth L. Wantink
IPC分类号： A61M31/00
CPC分类号： A61M25/008 , A61M25/001 , A61M25/0045 , A61M25/0068 , A61M25/0069 , A61M25/10 , A61M25/1025 , A61M25/104 , A61M2025/0047 , A61M2025/0081 , A61M2025/1093 , Y10T156/1005
摘要： A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon.
摘要翻译：一种气囊导管，其具有柔软的远侧末端构件，其具有非粘性内（衬）层材料和柔软的柔性外层材料，两种材料易于热粘合到导管气囊。

6. 发明授权

US07300415B2 Balloon catheter having an external guidewire 有权
标题翻译：气球导管具有外部导丝
公开(公告)号：US07300415B2
公开(公告)日：2007-11-27
申请号：US10326359
申请日：2002-12-20
申请人： Christopher McMurtry , Jeong S. Lee , Kenneth L. Wantink
发明人： Christopher McMurtry , Jeong S. Lee , Kenneth L. Wantink
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/0029 , A61M25/003 , A61M2025/0004 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M2025/1056
摘要： A catheter having an elongated shaft with an inflation lumen and a guidewire lumen, a balloon on a distal shaft section, and a proximal intermediate port proximal to the balloon and a distal intermediate port distal to the balloon, the intermediate ports being in communication with the guidewire lumen and being configured to slidably receive a guidewire therethrough so that the guidewire extends into or out of a proximal section of the guidewire lumen through the proximal intermediate port, extends along an outer surface of the balloon, and extends into or out of a distal section of the guidewire lumen through the distal intermediate port. The balloon is inflated in a patient's blood vessel to perform a medical procedure, with the section of the guidewire extending along an outer surface of the balloon providing improved balloon retention at the desired location in the blood vessel during inflation of the balloon.
摘要翻译：一种导管，其具有带有充气腔和导丝管腔的细长轴，远侧轴部上的球囊和靠近球囊的近端中间端口和远离球囊的远端中间端口，中间端口与导丝内腔并被构造成可滑动地容纳穿过其中的导丝，使得导丝通过近端中间端口延伸进入或离开导丝腔的近端部分，沿着球囊的外表面延伸，并延伸到远端导丝管腔通过远端中间端口的截面。气囊在患者的血管中充气以执行医疗程序，其中导丝线的部分沿球囊的外表面延伸，在球囊充气期间在血管中的期望位置提供改善的气囊保持。

7. 发明申请

US20090223624A1 CATHETER HAVING A READILY BONDABLE MULTILAYER SOFT TIP 有权
标题翻译：具有可自由粘合的多层柔性提示的导管
公开(公告)号：US20090223624A1
公开(公告)日：2009-09-10
申请号：US12468745
申请日：2009-05-19
申请人： Jeong S. Lee , Kenneth L. Wantink
发明人： Jeong S. Lee , Kenneth L. Wantink
IPC分类号： B29C63/18
CPC分类号： A61M25/008 , A61M25/001 , A61M25/0045 , A61M25/0068 , A61M25/0069 , A61M25/10 , A61M25/1025 , A61M25/104 , A61M2025/0047 , A61M2025/0081 , A61M2025/1093 , Y10T156/1005
摘要： A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon.
摘要翻译：一种气囊导管，其具有柔软的远侧末端部件，其具有非粘性内部（衬里）层材料和柔软的柔性外层材料，两种材料易于热粘合到导管气囊。

8. 发明授权

US07150853B2 Method of sterilizing a medical device 有权
公开(公告)号：US07150853B2
公开(公告)日：2006-12-19
申请号：US10002933
申请日：2001-11-01
申请人： Jeong S. Lee , Kenneth L. Wantink
发明人： Jeong S. Lee , Kenneth L. Wantink
IPC分类号： A61L2/08
CPC分类号： A61L2/087 , A61L2202/24 , A61M25/10
摘要： A method of sterilizing a medical device component, such as a catheter balloon, in which an electron beam (i.e., e-beam) is applied to the component in an evacuated or inert gas-filled container. The method of the invention allows for electron beam sterilization without significant degradation of the component polymeric material. In one embodiment, the device component is configured to be pressurized or expanded during use. The method of the invention provides a component with a rupture pressure that is not significantly decreased due to electron beam sterilization. Another aspect of the invention is a medical device component, e-beam sterilized according to a method of the invention. A variety of medical device components can be sterilized by the method of the invention, and particularly intracorporeal devices for therapeutic or diagnostic purposes, such as balloon catheters, catheter shafts and balloons, stent covers, and vascular grafts.

9. 发明授权

US08840743B2 Soft tip balloon catheter 有权
标题翻译：软尖端气囊导管
公开(公告)号：US08840743B2
公开(公告)日：2014-09-23
申请号：US13609968
申请日：2012-09-11
申请人： Kenneth L. Wantink , Jeong S. Lee , Justin K. Mann
发明人： Kenneth L. Wantink , Jeong S. Lee , Justin K. Mann
IPC分类号： B32B37/12 , A61M31/00
CPC分类号： B29C65/02 , A61M25/001 , A61M25/10 , A61M25/1034 , A61M2025/0047 , A61M2025/0081 , A61M2025/1075 , A61M2025/1093 , B29K2677/00 , B29K2995/0049 , B29L2009/00 , B29L2022/022 , B29L2023/005 , B29L2031/7543 , Y10T156/1005 , Y10T156/1015
摘要： Method for fabricating a balloon catheter including providing an inner tubular member having a distal section and a distal end with a lumen extending therein and forming a balloon having a distal leg with a first segment having a first diameter and a first wall thickness and a second segment having a second wall thickness. The second diameter is greater than the first diameter and the first wall thickness is greater than the second wall thickness. The distal end section of the inner tubular member can be positioned in the balloon and bonded to the first segment while reducing the diameter of the second segment. Method also provided for fabricating a multilayer balloon catheter including removing at least a portion of an outer layer from the distal leg of the balloon.
摘要翻译：一种用于制造球囊导管的方法，包括提供具有远侧部分和远端的内部管状构件，所述内部管状构件具有在其中延伸的内腔，并且形成具有远端腿部的气囊，所述远端腿部具有第一部分，所述第一部分具有第一直径和第一壁厚，具有第二壁厚。第二直径大于第一直径，第一壁厚大于第二壁厚。内管状构件的远端部分可以定位在球囊中并且结合到第一段上，同时减小第二段的直径。还提供了用于制造多层气囊导管的方法，其包括从气囊的远端腿部移除外层的至少一部分。

10. 发明申请

US20140074020A1 SOFT TIP BALLOON CATHETER 有权
标题翻译：软头气球导管
公开(公告)号：US20140074020A1
公开(公告)日：2014-03-13
申请号：US13609968
申请日：2012-09-11
申请人： Kenneth L. Wantink , Jeong S. Lee , Justin K. Mann
发明人： Kenneth L. Wantink , Jeong S. Lee , Justin K. Mann
IPC分类号： B29C65/02 , A61M25/10
CPC分类号： B29C65/02 , A61M25/001 , A61M25/10 , A61M25/1034 , A61M2025/0047 , A61M2025/0081 , A61M2025/1075 , A61M2025/1093 , B29K2677/00 , B29K2995/0049 , B29L2009/00 , B29L2022/022 , B29L2023/005 , B29L2031/7543 , Y10T156/1005 , Y10T156/1015
摘要： Method for fabricating a balloon catheter including providing an inner tubular member having a distal section and a distal end with a lumen extending therein and forming a balloon having a distal leg with a first segment having a first diameter and a first wall thickness and a second segment having a second wall thickness. The second diameter is greater than the first diameter and the first wall thickness is greater than the second wall thickness. The distal end section of the inner tubular member can be positioned in the balloon and bonded to the first segment while reducing the diameter of the second segment. Method also provided for fabricating a multilayer balloon catheter including removing at least a portion of an outer layer from the distal leg of the balloon.
摘要翻译：一种用于制造球囊导管的方法，包括提供具有远侧部分和远端的内部管状构件，所述内部管状构件具有在其中延伸的内腔，并且形成具有远端腿部的气囊，所述远端腿部具有第一部分，所述第一部分具有第一直径和第一壁厚，具有第二壁厚。第二直径大于第一直径，第一壁厚大于第二壁厚。内管状构件的远端部分可以定位在球囊中并且结合到第一段上，同时减小第二段的直径。还提供了用于制造多层气囊导管的方法，其包括从气囊的远端腿部移除外层的至少一部分。

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