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    • 5. 发明授权
    • Waste gas system for bioreactors
    • 生物反应器废气系统
    • US08268059B2
    • 2012-09-18
    • US12653506
    • 2009-12-15
    • Juergen van den BoogardGerid HellwigJens LudwigOscar-Werner ReifStefan Weisshaar
    • Juergen van den BoogardGerid HellwigJens LudwigOscar-Werner ReifStefan Weisshaar
    • B01D50/00
    • C12M29/20
    • The invention relates to a waste gas system for bioreactors having a hydrophobic sterile filter, arranged at the end, and a heat exchanger which protects the sterile filter against blocking by liquid media. The gas outflow duct for discharging waste gas from a bioreactor vessel is divided in a cooling zone of the heat exchanger into a multiplicity of subducts and is extended in a heating zone of the heat exchanger to a calming zone. Due to the multiplicity of subducts, a considerably larger surface area for the removal of heat from the waste gas is available, with the result that in the case of laminar flow of the waste gas through the subducts a high effectiveness of the separation of liquids from the waste gas can be achieved. In the heating zone, the waste gas can heat up again due to the reduced flow rate until it reaches the hydrophobic sterile filter by way of taking up heat from the surroundings to a such a degree that the relative vapor contents are below 100% and separation of liquids from residual vapors at or in the hydrophobic sterile filter is precluded.
    • 本发明涉及一种用于生物反应器的废气系统,其具有布置在其末端的疏水性无菌过滤器和保护无菌过滤器免受液体介质堵塞的热交换器。 用于从生物反应器容器排出废气的气体流出管在热交换器的冷却区中分成多个副产物,并在热交换器的加热区中延伸到一个镇定区。 由于多余的下降,可以获得相当大的用于从废气中除去热量的表面积,结果是在废气通过下沉层流的情况下,液体从液体中分离的高效率 可以实现废气。 在加热区中,废气可以由于流速降低而再次加热,直到其通过从周围环境吸收热量达到疏水性无菌过滤器至相对蒸汽含量低于100%的程度并且分离 的疏水性无菌过滤器中或其中残留蒸气的液体被排除。