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    • 3. 发明申请
    • MEDICINE FOR TREATMENT OF A CARCINOMA
    • 治疗癌症的药物
    • US20120082732A1
    • 2012-04-05
    • US13313664
    • 2011-12-07
    • JENS FEHRERalf NankeMartin Stetter
    • JENS FEHRERalf NankeMartin Stetter
    • A61K38/17A61K9/14A61K31/7088A61P37/04A61K35/76A61K39/395A61P35/00
    • A61K9/1676A61K9/0009
    • In a method for treating a carcinoma in a patient, a medicine is administered via the blood stream of the patient that appears, to the patient's immune system, that tissue of the carcinoma is an inflammation source. The medicine employs two active components that are coupled to each other in a form allowing administration of the two active components to the carcinoma via the blood stream of the patient. A first of the active components is at least one coupling molecule that specifically tethers to a target molecule formed by cancer tissue of the carcinoma. A second of the active ingredients is at least one signal molecule typical to inflammation, or at least one originating molecule encoding such a signal molecule, that induces the immune system of the body to attack the cancer cells.
    • 在用于治疗患者癌症的方法中,药物通过出现在患者的免疫系统中的患者的血流中被施用,癌的组织是炎症源。 药物使用两种活性组分,其以允许经由患者的血液将两种活性成分施用于癌的形式彼此偶联。 活性组分中的第一个是至少一个特异性地连接到由癌的癌组织形成的靶分子的偶联分子。 活性成分中的第二种是至少一种典型的炎症信号分子,或至少一种编码这种信号分子的起始分子,其诱导身体的免疫系统侵袭癌细胞。