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    • 3. 发明授权
    • Article to be inserted in a body cavity having biologically inhibiting surfaces and use and preparation of the article
    • 将物品插入具有生物抑制表面的体腔内并使用和制备制品
    • US08708978B2
    • 2014-04-29
    • US11886449
    • 2006-03-17
    • Per MøllerAnette Alsted Rasmussen
    • Per MøllerAnette Alsted Rasmussen
    • A61M5/32
    • A61L29/10A61L29/14
    • An article to be inserted in a human or animal body cavity, use of the article and preparation thereof. The article has a biologically inhibiting arrangement of electrically connected electrode materials in direct contact with each other on one or more surfaces of the article. The arrangement includes as electrode materials a metallic anode material and a cathode material, where the potential of the cathode material is higher than the potential of the anode material. The cathode material is an electrically conductive material selected among certain non-metallic materials. The arrangement provided on the article releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with a body fluid. The article can be designed with a controlled release rate suitable for the purpose in question for example an initial high rate of ion release after insertion of a catheter to combat bacteria introduced during the insertion followed by a prolonged release at a lower rate to maintain a low level of bacteria.
    • 要插入人体或动物体腔内的物品,使用制品及其制备。 该物品具有在物品的一个或多个表面上彼此直接接触的电连接电极材料的生物学抑制布置。 该装置包括作为电极材料的金属阳极材料和阴极材料,其中阴极材料的电位高于阳极材料的电位。 阴极材料是从某些非金属材料中选择的导电材料。 当生物抑制装置与体液接触时,提供在制品上的布置释放金属阳极材料的生物抑制离子或这种离子的复合物。 该制品可以设计成适合于所讨论的目的的控制释放速率,例如在插入导管以抵抗在插入期间引入的细菌中的初始高速率离子释放,然后以较低的速率延长释放以维持低 细菌水平。