专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050090507A1 Pyrazolopyridazine derivatves 失效
标题翻译：吡唑并哒嗪衍生物
公开(公告)号：US20050090507A1
公开(公告)日：2005-04-28
申请号：US10499179
申请日：2002-12-11
申请人： Jennifer Badiang , Scott Dickerson , Philip Harris , David Jung , Michael Peel , Michael Reno , Tara Rheault , Kirk Stevens , Francis Tavares , James Veal
发明人： Jennifer Badiang , Scott Dickerson , Philip Harris , David Jung , Michael Peel , Michael Reno , Tara Rheault , Kirk Stevens , Francis Tavares , James Veal
IPC分类号： A61K31/506 , A61K31/5377 , A61K45/00 , A61P35/00 , A61P43/00 , C07D487/04 , A61K31/519
CPC分类号： C07D487/04
摘要： Fused pyradazine derivatives, which are useful as CDK inhibitors are described herein. The described invention also includes methods of making such fused pyradazines derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译：本文描述了可用作CDK抑制剂的稠合的哒嗪衍生物。所述的发明还包括制备这种稠合吡嗪嗪衍生物的方法以及使用其来治疗过度增殖性疾病的方法。

2. 发明申请

US20080051395A1 2-Pyrimidinyl Pyrazolopyridine Erbb Kinase Inhibitors 失效
标题翻译： 2-嘧啶基吡唑并吡啶Erbb激酶抑制剂
公开(公告)号：US20080051395A1
公开(公告)日：2008-02-28
申请号：US11721504
申请日：2005-12-06
申请人： David Uehling , Kirk Stevens , Scott Dickerson , Alex Waterson , Philip Harris , Douglas Sammond , Robert Hubbard , Holly Emerson , Joseph Wilson
发明人： David Uehling , Kirk Stevens , Scott Dickerson , Alex Waterson , Philip Harris , Douglas Sammond , Robert Hubbard , Holly Emerson , Joseph Wilson
IPC分类号： A61K31/506 , A61K31/5377 , A61P35/00 , C07D239/24 , C07D413/14
CPC分类号： C07D471/04
摘要： The present invention provides 2-pyrimidinyl pyrazolopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.
摘要翻译：本发明提供2-嘧啶基吡唑并吡啶化合物，含有它们的组合物，以及制备方法及其作为药剂的用途。

3. 发明申请

US20060205740A1 Chemical compounds 审中-公开
标题翻译：化合物
公开(公告)号：US20060205740A1
公开(公告)日：2006-09-14
申请号：US10568052
申请日：2004-08-11
申请人： Michael Reno , Kirk Stevens , Alex Waterson , Yuemei Zhang
发明人： Michael Reno , Kirk Stevens , Alex Waterson , Yuemei Zhang
IPC分类号： C07D403/02 , C07D417/02 , A61K31/506
CPC分类号： C07D239/42 , C07D401/06 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/06 , C07D409/06 , C07D409/14 , C07D413/14 , C07D417/06 , C07D417/14
摘要： The present invention discloses pyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such pyrimidine derivatives are useful in the treatment of diseases associated with inappropriate ErbB family kinase.
摘要翻译：本发明公开了嘧啶衍生物，组合物和含有它们的药物，以及制备和使用这些化合物，组合物和药物的方法。这样的嘧啶衍生物可用于治疗与不适当的ErbB家族激酶相关的疾病。

4. 发明申请

US20100204196A1 2-[2--1H-Pyrrolo[2,3-D]Pyrimidin-4-YL)Amino] Benzamide Derivatives As IGF-1R Inhibitors For The Treatment Of Cancer 有权
标题翻译： 2- [2- [1H-吡咯并[2,3-D]嘧啶-4-基）氨基]苯甲酰胺衍生物作为IGF-1R抑制剂治疗癌症
公开(公告)号：US20100204196A1
公开(公告)日：2010-08-12
申请号：US12671960
申请日：2008-08-06
申请人： Stanley Dawes Chamberlain , Felix Deanda, JR. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
发明人： Stanley Dawes Chamberlain , Felix Deanda, JR. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
IPC分类号： A61K31/397 , C07D487/04 , A61K31/519 , A61K31/496 , A61K31/5377 , A61K31/551 , A61P35/00
CPC分类号： C07D487/04 , C07D487/14
摘要： Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
摘要翻译：式（I）所示的新型吡咯并嘧啶及其药学上可接受的衍生物。该化合物可用于抑制IGF-1R。

5. 发明申请

US20080300242A1 Imidazopyridine Kinase Inhibitors 有权
标题翻译：咪唑并吡啶激酶抑制剂
公开(公告)号：US20080300242A1
公开(公告)日：2008-12-04
申请号：US12128099
申请日：2008-05-28
申请人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
发明人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
IPC分类号： A61K31/496 , C07D401/04 , C07D279/12 , A61P35/00 , A61K31/541 , A61K31/506
CPC分类号： C07D471/04
摘要： The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译：本发明提供咪唑并吡啶化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。

6. 发明申请

US20060065005A1 Ice maker for refrigerator 失效
公开(公告)号：US20060065005A1
公开(公告)日：2006-03-30
申请号：US10950062
申请日：2004-09-24
申请人： Joseph Comerci , Timothy Gregori , Kirk Stevens
发明人： Joseph Comerci , Timothy Gregori , Kirk Stevens
IPC分类号： F25C1/00
CPC分类号： F25C5/04 , F25C1/04 , F25C5/02 , F25C5/187 , F25C2400/14 , F25C2600/04
摘要： An ice maker for a refrigerator/freezer having a control module for more reliably driving a rotatable ice ejector for removing ice bodies from a mold of the ice maker and for refilling mold cavities with water. The control module has an ice ejector drive with a drive coupling that includes a gear wheel and an ejector shaft section, both made of hard plastic material, preferably a polymide resin, for transmitting higher torque to the rotary ice ejector without failure of the plastic drive components. In one embodiment, a drive sleeve on the gear wheel and a drive shaft section have a spline coupling for more effectively distributing driving forces in the drive coupling. In another embodiment, a metallic collar is tightly positioned over the gear wheel sleeve for enhancing torque transmission in the drive coupling. The control module further is operable for refilling the ice maker mold cavities to a predetermined level during each cycle of operation notwithstanding slight alterations in positioning of water fill switching contact due to manufacturing tolerances or forces to which the ice maker is subjected during shipping, handling or installation.

7. 发明授权

US08093239B2 Imidazopyridine kinase inhibitors 有权
标题翻译：咪唑并吡啶激酶抑制剂
公开(公告)号：US08093239B2
公开(公告)日：2012-01-10
申请号：US12128099
申请日：2008-05-28
申请人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
发明人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
IPC分类号： A61K31/55 , A61K31/505 , A61K31/497 , A61K31/535 , C07D243/08 , C07D413/14 , C07D403/14 , C07D239/02
CPC分类号： C07D471/04
摘要： The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译：本发明提供咪唑并吡啶化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。

8. 发明授权

US07981903B2 2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer 有权
标题翻译： 2- [2- {苯基氨基} -1H-吡咯并[2,3-D]嘧啶-4-基）氨基]苯甲酰胺衍生物作为治疗癌症的IGF-1R抑制剂
公开(公告)号：US07981903B2
公开(公告)日：2011-07-19
申请号：US12671960
申请日：2008-08-06
申请人： Stanley Dawes Chamberlain , Felix Deanda, Jr. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
发明人： Stanley Dawes Chamberlain , Felix Deanda, Jr. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： C07D487/04 , C07D487/14
摘要： Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
摘要翻译：式（I）所示的新型吡咯并嘧啶及其药学上可接受的衍生物。该化合物可用于抑制IGF-1R。

9. 发明申请

US20070079626A1 Ice maker for refrigerator 有权
标题翻译：制冰机冰箱
公开(公告)号：US20070079626A1
公开(公告)日：2007-04-12
申请号：US11636834
申请日：2006-12-11
申请人： Joseph Comerci , Timothy Gregori , Kirk Stevens
发明人： Joseph Comerci , Timothy Gregori , Kirk Stevens
IPC分类号： F25C1/00 , F25C1/22
CPC分类号： F25C5/04 , F25C1/04 , F25C5/02 , F25C5/187 , F25C2400/14 , F25C2600/04
摘要： An ice maker for a refrigerator/freezer having a control module for more reliably driving a rotatable ice ejector for removing ice bodies from a mold of the ice maker and for refilling mold cavities with water. The control module has an ice ejector drive with a drive coupling that includes a gear wheel and an ejector shaft section, both made of hard plastic material, preferably a polymide resin, for transmitting higher torque to the rotary ice ejector without failure of the plastic drive components. In one embodiment, a drive sleeve on the gear wheel and a drive shaft section have a spline coupling for more effectively distributing driving forces in the drive coupling. In another embodiment, a metallic collar is tightly positioned over the gear wheel sleeve for enhancing torque transmission in the drive coupling. The control module further is operable for refilling the ice maker mold cavities to a predetermined level during each cycle of operation notwithstanding slight alterations in positioning of water fill switching contact due to manufacturing tolerances or forces to which the ice maker is subjected during shipping, handling or installation.
摘要翻译：一种用于冰箱/冷冻机的制冰机，具有用于更可靠地驱动可旋转的冰喷射器的控制模块，用于从制冰机的模具中除去冰体并用水重新填充模腔。该控制模块具有一个具有驱动联轴器的驱动联轴器的驱动联轴器，该驱动联轴器包括齿轮和推出轴部分，两者均由硬塑料材料制成，优选为聚酰亚胺树脂，用于将更高扭矩传递到旋转式冰喷射器，而不会损坏塑料驱动组件。在一个实施例中，齿轮上的驱动套筒和驱动轴部分具有用于更有效地分配驱动联接器中的驱动力的花键联接件。在另一个实施例中，金属套环紧紧地定位在齿轮套上方，以增强驱动联轴器中的转矩传递。控制模块还可操作用于在每个操作周期期间将制冰机模具腔重新填充到预定水平，尽管由于在运输，处理或制造过程中制冰机遭受的制造公差或力，水填充开关触点的定位略有改变安装。

10. 发明授权

US07166597B2 Fused pyrazole derivatives being protein kinase inhibitors 失效
标题翻译：融合的吡唑衍生物是蛋白激酶抑制剂
公开(公告)号：US07166597B2
公开(公告)日：2007-01-23
申请号：US10362146
申请日：2001-08-22
申请人： Michael John Alberti , Ian Robert Baldwin , Mui Cheung , Stuart Cockerill , Stephen Flack , Philip Anthony Harris , David Kendall Jung , Gregory Peckham , Michael Robert Peel , Jennifer Gabriel Badiang , Kirk Stevens , James Marvin Veal
发明人： Michael John Alberti , Ian Robert Baldwin , Mui Cheung , Stuart Cockerill , Stephen Flack , Philip Anthony Harris , David Kendall Jung , Gregory Peckham , Michael Robert Peel , Jennifer Gabriel Badiang , Kirk Stevens , James Marvin Veal
IPC分类号： C07D471/04 , A61K31/437 , C07F5/02
CPC分类号： C07D471/04
摘要： Compounds of Formula (I): salts or solvates or physiologically functional derivatives thereof, wherein Z is CH or N, and R1, R2, and R4 are various substituent groups, are protein kinase inhibitors
摘要翻译：式（I）的化合物：其盐或溶剂合物或其生理功能衍生物，其中Z为CH或N，R 1，R 2和R 4 各种取代基是蛋白激酶抑制剂

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式