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1. 发明授权

US08906904B2 Alkoxy pyrazoles as soluble guanylate cyclase activators 有权
标题翻译：烷氧基吡唑作为可溶性鸟苷酸环化酶活化剂
公开(公告)号：US08906904B2
公开(公告)日：2014-12-09
申请号：US14016452
申请日：2013-09-03
申请人： Jehrod Burnett Brenneman , John Ginn , Michael D. Lowe , Christopher Ronald Sarko , Edward S. Tasber , Zhonghua Zhang
发明人： Jehrod Burnett Brenneman , John Ginn , Michael D. Lowe , Christopher Ronald Sarko , Edward S. Tasber , Zhonghua Zhang
IPC分类号： C07D401/14 , C07D405/14 , C07D498/04
CPC分类号： C07D401/14 , C07D405/14 , C07D493/08 , C07D498/04
摘要： The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
摘要翻译：本发明涉及式（I）化合物及其药学上可接受的盐，其中R 1，R 2，R 3，R 4，R 5，R 6和R 7如本文所定义。本发明还涉及包含这些化合物的药物组合物，使用这些化合物治疗各种疾病和病症的方法，制备这些化合物的方法和可用于这些方法的中间体。

2. 发明授权

US07770386B2 Filter desulfation system and method 失效
标题翻译：过滤脱硫系统及方法
公开(公告)号：US07770386B2
公开(公告)日：2010-08-10
申请号：US11022692
申请日：2004-12-28
申请人： Michael D. Lowe , Wade J. Robel , Maarten Verkiel , James J. Driscoll
发明人： Michael D. Lowe , Wade J. Robel , Maarten Verkiel , James J. Driscoll
IPC分类号： F01N3/00
CPC分类号： F01N3/0814 , F01N3/031 , F01N3/035 , F01N3/0842 , F01N3/0885 , F01N2250/02 , F01N2610/03 , F01N2610/08
摘要： A method of removing sulfur from a filter system of an engine includes continuously passing an exhaust flow through a desulfation leg of the filter system during desulfation. The method also includes sensing at least one characteristic of the exhaust flow and modifying a flow rate of the exhaust flow during desulfation in response to the sensing.
摘要翻译：从发动机的过滤器系统中除去硫的方法包括在脱硫期间使废气流连续地通过过滤系统的脱硫腿。该方法还包括响应于感测而检测排气流中的至少一个特性并且在脱硫期间改变排气流的流量。

3. 发明授权

US07677028B2 Particulate trap regeneration temperature control system 有权
标题翻译：微粒陷阱再生温度控制系统
公开(公告)号：US07677028B2
公开(公告)日：2010-03-16
申请号：US11363245
申请日：2006-02-28
申请人： David J. Kapparos , Michael D. Lowe
发明人： David J. Kapparos , Michael D. Lowe
IPC分类号： F01N3/025
CPC分类号： F01N9/002 , F01N3/0256 , F02D41/0245 , F02D41/029 , F02D2200/0802 , Y02T10/26 , Y02T10/47
摘要： In one aspect, the present disclosure is directed to a particulate trap regeneration temperature control system. The system may include a particulate trap configured to remove one or more types of particulate matter from an exhaust flow of an engine. The system may also include a heating system configured to increase the temperature of the particulate trap. The system may further include a controller configured to control operation of the heating system during execution of a thermal regeneration event of the particulate trap. The controller may control operation of the heating system by effectuating a first temperature increase of the particulate trap at a predetermined rate up to a first predetermined temperature. The controller may also be configured to effectuate a first temperature hold by maintaining the temperature of the particulate trap at the first predetermined temperature for a predetermined amount of time. The controller may further be configured to effectuate a second temperature increase of the particulate trap at a predetermined rate to a higher second predetermined temperature. In addition, the controller may also be configured to effectuate a second temperature hold by maintaining the temperature of the particulate trap at the second predetermined temperature for a predetermined amount of time.
摘要翻译：在一个方面，本发明涉及一种颗粒捕集器再生温度控制系统。该系统可以包括构造成从发动机的排气流中去除一种或多种类型的颗粒物质的微粒捕集器。该系统还可以包括被配置为增加颗粒捕集器的温度的加热系统。该系统还可以包括控制器，该控制器被配置为在颗粒捕集器的热再生事件的执行期间控制加热系统的操作。控制器可以通过以预定速率直到第一预定温度来实现颗粒捕集器的第一温度升高来控制加热系统的操作。控制器还可以被配置为通过将颗粒捕集器的温度保持在第一预定温度达预定的时间量来实现第一温度保持。控制器还可以被配置为以预定的速率将颗粒捕集器的第二温度升高实现到更高的第二预定温度。此外，控制器还可以被配置为通过将颗粒捕集器的温度保持在第二预定温度达预定时间量来实现第二温度保持。

4. 发明授权

US5787069A Protective cover for an optical disc 失效
标题翻译：光盘保护盖
公开(公告)号：US5787069A
公开(公告)日：1998-07-28
申请号：US713523
申请日：1996-09-13
申请人： Michael D. Lowe , Tom A. Borhot , Paule Pijo William Zono Andric , Oliver J. Medic , Warren J. Blatz , Douglas Christian Greening , Stephen Arthur Withington
发明人： Michael D. Lowe , Tom A. Borhot , Paule Pijo William Zono Andric , Oliver J. Medic , Warren J. Blatz , Douglas Christian Greening , Stephen Arthur Withington
IPC分类号： G11B7/24 , G11B23/03 , G11B33/14
CPC分类号： G11B7/24 , G11B23/0316 , G11B23/032 , G11B23/0326
摘要： There is provided a new and useful protective cover for an optical disc of circular configuration having a circular aperture centered therein and having an outer edge. The protective cover is a sheet of film of generally circular configuration corresponding to the configuration of the disc, wherein the film is of a material that will not interfere with the read process of the disc when the cover is in place about the disc. The protective cover has a plurality of clasps spaced about a circumferential edge of the film to engage the disc about its outer edge in a snap fit. The invention also relates to a method of applying such a protective cover to such an optical disc comprising the steps of holding the cover with the clasps in a closed position oriented relative to the film toward said disc, expanding the clasps to an open position wider than an outside diameter of the disc, placing the disc within the expanded clasps, concentric with the cover and returning the clasps to the closed position whereby they engage the disc about the outer edge in a snap fit.
摘要翻译：提供了一种用于圆形构造的光盘的新的和有用的保护盖，其具有以其中心的圆形孔并具有外边缘。保护罩是与盘的结构相对应的大致圆形构造的薄片，其中，当盖在盘周围的适当位置时，该膜是不会干扰盘的读取过程的材料。保护罩具有围绕胶片的圆周边缘间隔开的多个扣环，以卡扣配合使其围绕其外边缘接合。本发明还涉及一种将这样的保护盖应用于这种光盘的方法，包括以下步骤：将盖子保持在相对于胶片朝向所述盘定位的关闭位置中，将该卡扣扩大到比盘的外径，将盘放置在膨胀的钩中，与盖同心并将扣返回到关闭位置，由此它们以卡扣配合的方式接合盘周围的外边缘。

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