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1. 发明授权

US08113205B2 Contraceptive system and method of use 有权
标题翻译：避孕系统及使用方法
公开(公告)号：US08113205B2
公开(公告)日：2012-02-14
申请号：US12035219
申请日：2008-02-21
申请人： Jeffrey P. Callister , William S. Tremulis , Denis S. Harges
发明人： Jeffrey P. Callister , William S. Tremulis , Denis S. Harges
IPC分类号： A61F6/06
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12099 , A61B17/1214 , A61B17/12159 , A61B2017/00557 , A61F6/22 , A61F6/225 , A61F2002/30092 , A61F2210/0014
摘要： A device and method of using the device for contraception or sterilization and particularly for reversible contraception by occluding a reproductive lumen to prevent the passage of reproductive cells through the lumen for a desired period of time until the patient wishes to become fertile again and then be reopened. The occluding member preferably comprises a tubular framework formed from a shape memory material configured to be implanted in a reproductive lumen. The occluding member is implanted within a body lumen, secured to the wall of the reproductive lumen and then collapsed to collapse the wall and occlude the lumen. Alternatively, the occluding member may be collapsed upon a solid plug. The closure of the reproductive lumen may be reversed by introducing a balloon catheter and by a series of inflations of the balloon reexpanding the collapsed occluding member or by removing the plug. The occluding member and the plug may be configured to facilitate endothelialization, to provoke an inflammatory responses or to deliver a drug.
摘要翻译：一种使用该装置进行避孕或灭菌的装置和方法，特别是通过闭塞生殖腔以避免生殖细胞通过管腔通过所需时间直到患者再次变得可育，然后重新开放来进行可逆避孕。。闭塞构件优选地包括由构造成植入生殖腔内的形状记忆材料形成的管状框架。将闭塞构件植入体腔内，固定在生殖腔的壁上，然后收缩以折叠壁并闭塞内腔。或者，封闭构件可以在固体塞上折叠。可以通过引入球囊导管和通过重新膨胀收缩的封闭构件的球囊的一系列充气或通过移除塞子来反转生殖腔的闭合。闭塞构件和塞子可以被配置为促进内皮化，引发炎症反应或递送药物。

2. 发明授权

US6096052A Occluding device and method of use 失效
公开(公告)号：US6096052A
公开(公告)日：2000-08-01
申请号：US112085
申请日：1998-07-08
申请人： Jeffrey P. Callister , William S. Tremulis
发明人： Jeffrey P. Callister , William S. Tremulis
IPC分类号： A61B19/00 , A61B17/12 , A61B17/42 , A61F2/84 , A61F6/22 , A61B6/20 , A61B6/22
CPC分类号： A61F6/22
摘要： A device for occluding a body lumen, and particularly contraceptive or sterilization device for occluding a reproductive tract or lumen to prevent the passage of reproductive cells through the tract or lumen, generally comprising a tubular member, and a mesh member, transversely disposed on the tubular member lumen. The mesh member is permeable to allow for tissue ingrowth, which produces a tissue impregnated mesh occluding the body lumen. The occluding device of the invention can be used in the fallopian tubes of a female patient, the vas deferens of a male patient, or other body lumen.

3. 发明授权

US08707957B2 Contraceptive system and method of use 有权
标题翻译：避孕系统及使用方法
公开(公告)号：US08707957B2
公开(公告)日：2014-04-29
申请号：US12172807
申请日：2008-07-14
申请人： Jeffrey P. Callister , William S. Tremulis , Denise S. Harges
发明人： Jeffrey P. Callister , William S. Tremulis , Denise S. Harges
IPC分类号： A61F6/20
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12099 , A61B17/1214 , A61B17/12159 , A61B2017/00557 , A61F6/22 , A61F6/225 , A61F2002/30092 , A61F2210/0014
摘要： A device and method of using the device for contraception or sterilization and particularly for reversible contraception by occluding a reproductive lumen to prevent the passage of reproductive cells through the lumen for a desired period of time until the patient wishes to become fertile again and then be reopened. The occluding member preferably comprises a tubular framework formed from a shape memory material configured to be implanted in a reproductive lumen. The occluding member is implanted within a body lumen, secured to the wall of the reproductive lumen and then collapsed to collapse the wall and occlude the lumen. Alternatively, the occluding member may be collapsed upon a solid plug. The closure of the reproductive lumen may be reversed by introducing a balloon catheter and by a series of inflations of the balloon reexpanding the collapsed occluding member or by removing the plug. The occluding member and the plug may be configured to facilitate endothelialization, to provoke an inflammatory responses or to deliver a drug.
摘要翻译：一种使用该装置进行避孕或灭菌的装置和方法，特别是通过闭塞生殖腔以避免生殖细胞通过管腔通过所需时间直到患者再次变得可育，然后重新开放来进行可逆避孕。。闭塞构件优选地包括由构造成植入生殖腔内的形状记忆材料形成的管状框架。将闭塞构件植入体腔内，固定在生殖腔的壁上，然后收缩以折叠壁并闭塞内腔。或者，封闭构件可以在固体塞上折叠。可以通过引入球囊导管和通过重新膨胀收缩的封闭构件的球囊的一系列充气或通过移除塞子来反转生殖腔的闭合。闭塞构件和塞子可以被配置为促进内皮化，引发炎症反应或递送药物。

4. 发明申请

US20080135054A1 CONTRACEPTIVE SYSTEM AND METHOD OF USE 有权
标题翻译：承包系统和使用方法
公开(公告)号：US20080135054A1
公开(公告)日：2008-06-12
申请号：US12035219
申请日：2008-02-21
申请人： Jeffrey P. Callister , William S. Tremulis , Denise S. Harges
发明人： Jeffrey P. Callister , William S. Tremulis , Denise S. Harges
IPC分类号： A61F6/22
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12099 , A61B17/1214 , A61B17/12159 , A61B2017/00557 , A61F6/22 , A61F6/225 , A61F2002/30092 , A61F2210/0014
摘要： A device and method of using the device for contraception or sterilization and particularly for reversible contraception by occluding a reproductive lumen to prevent the passage of reproductive cells through the lumen for a desired period of time until the patient wishes to become fertile again and then be reopened. The occluding member preferably comprises a tubular framework formed from a shape memory material configured to be implanted in a reproductive lumen. The occluding member is implanted within a body lumen, secured to the wall of the reproductive lumen and then collapsed to collapse the wall and occlude the lumen. Alternatively, the occluding member may be collapsed upon a solid plug. The closure of the reproductive lumen may be reversed by introducing a balloon catheter and by a series of inflations of the balloon reexpanding the collapsed occluding member or by removing the plug. The occluding member and the plug may be configured to facilitate endothelialization, to provoke an inflammatory responses or to deliver a drug.
摘要翻译：一种使用该装置进行避孕或灭菌的装置和方法，特别是通过闭塞生殖腔以避免生殖细胞通过管腔通过所需时间直到患者再次变得可育，然后重新开放来进行可逆避孕。。闭塞构件优选地包括由构造成植入生殖腔内的形状记忆材料形成的管状框架。将闭塞构件植入体腔内，固定在生殖腔的壁上，然后收缩以折叠壁并闭塞内腔。或者，封闭构件可以在固体塞上折叠。可以通过引入球囊导管和通过重新膨胀收缩的封闭构件的球囊的一系列充气或通过移除塞子来反转生殖腔的闭合。闭塞构件和塞子可以被配置为促进内皮化，引发炎症反应或递送药物。

5. 发明授权

US09713549B2 Contraceptive with permeable and impermeable components 有权
公开(公告)号：US09713549B2
公开(公告)日：2017-07-25
申请号：US11047319
申请日：2005-01-31
申请人： Jeffrey P. Callister , William S. Tremulis
发明人： Jeffrey P. Callister , William S. Tremulis
IPC分类号： A61F6/22 , A61B17/12 , A61F6/20 , A61B17/00
CPC分类号： A61F6/22 , A61B17/0057 , A61B17/12022 , A61B17/12136 , A61B17/1215 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B17/12181 , A61B2017/12054 , A61B2017/12095 , A61F6/20 , A61F6/225
摘要： An device for occluding a body lumen such as a reproductive lumen which includes an occluding component having an impervious barrier to provide initial occlusion of the body lumen and a permeable body to facilitate tissue ingrowth which provides long term occlusion of the body lumen. The device and the method of using the device is particularly suitable for contraception.

6. 发明申请

US20120253120A1 ENDOSCOPIC DELIVERY OF MEDICAL DEVICES 审中-公开
标题翻译：医疗器械内窥镜输送
公开(公告)号：US20120253120A1
公开(公告)日：2012-10-04
申请号：US13525162
申请日：2012-06-15
申请人： Jeffrey P. Callister , William S. Tremulis , Laura Kemp , Paul M. Stull
发明人： Jeffrey P. Callister , William S. Tremulis , Laura Kemp , Paul M. Stull
IPC分类号： A61B1/018
CPC分类号： A61B1/018 , A61B1/00082 , A61B1/00133 , A61B1/04 , A61B1/303 , A61B5/4839 , A61B17/12022 , A61B17/12172 , A61B17/12177 , A61B2017/1205 , A61B2017/12054 , A61B2017/4233 , A61B2090/037 , A61F6/225
摘要： The invention is directed to an endoscopic assembly having an endoscope, particularly a flexible hysteroscope and an outer sheath disposed about a length of the shaft of the hysteroscope which has an expandable member such as an inflatable balloon for sealing the assembly within a body lumen or cavity. Specifically, the endoscope assembly is configured for delivery of an occlusive contraceptive member to the patient's fallopian tube. The invention is also directed to an endoscope having a driving member for movement of a medical device within the working lumen of an endoscope. In one embodiment the driving member is a friction wheel which engages an elongated medical device disposed within the working channel of the endoscope to effect longitudinal movement of the medical device.
摘要翻译：本发明涉及具有内窥镜，特别是柔性宫腔镜的内窥镜组件和围绕宫腔镜的轴的长度设置的外护套，其具有可膨胀构件，例如可膨胀气囊，用于将组件密封在体腔或腔内。具体地，内窥镜组件构造成用于将闭塞性避孕构件输送到患者的输卵管。本发明还涉及具有用于在内窥镜的工作腔内移动医疗装置的驱动部件的内窥镜。在一个实施例中，驱动构件是摩擦轮，其接合设置在内窥镜的工作通道内的细长医疗装置，以实现医疗装置的纵向移动。

7. 发明授权

US08689792B2 Occlusion device and system for occluding a reproductive body lumen 有权
标题翻译：用于闭塞生殖体腔的闭塞装置和系统
公开(公告)号：US08689792B2
公开(公告)日：2014-04-08
申请号：US12991907
申请日：2009-05-18
申请人： Jose' W. Jimenez , James R. Mujwid , William S. Tremulis , John R. Frigstad , Karl A. Jagger , Kevin R. Arnal , Jeffrey P. Callister
发明人： Jose' W. Jimenez , James R. Mujwid , William S. Tremulis , John R. Frigstad , Karl A. Jagger , Kevin R. Arnal , Jeffrey P. Callister
IPC分类号： A61B17/08
CPC分类号： A61F6/005 , A61F6/06 , A61F6/22 , A61F6/225
摘要： A system and method of occluding a reproductive body lumen (34) to prevent the passage of reproductive cells through body lumen is disclosed. The system can include a catheter delivery system (10) having a handle device (18), a catheter (10) operatively coupled with the handle device (20), and an occluding device adapted for deployment within the body lumen. The handle device can include a damper device adapted to reduce the vibration on the handle device from deployment of the occluding device from the catheter. Further, the handle device can include an indexing member operatively coupled with the catheter to provide indexing of the catheter.
摘要翻译：公开了一种闭塞生殖体腔（34）以防止生殖细胞通过体腔通过的系统和方法。该系统可以包括具有手柄装置（18）的导管输送系统（10），与手柄装置（20）可操作地连接的导管（10）和适于部署在体腔内的闭塞装置。手柄装置可以包括阻尼器装置，其适于减少手柄装置上的振动，以避免将阻塞装置从导管部署。此外，手柄装置可以包括与导管可操作地连接以提供导管的分度的分度构件。

8. 发明申请

US20140014115A1 METHODS AND APPARATUS FOR OCCLUDING REPRODUCTIVE TRACTS TO EFFECT CONTRACEPTION 审中-公开
标题翻译：用于影响生殖因子以影响受体的方法和装置
公开(公告)号：US20140014115A1
公开(公告)日：2014-01-16
申请号：US14030814
申请日：2013-09-18
申请人： Jeffrey P. Callister , William S. Tremulis
发明人： Jeffrey P. Callister , William S. Tremulis
IPC分类号： A61F6/22
CPC分类号： A61F6/22 , A61F6/225
摘要： Systems and methods of visibly marking a reproductive tract, e.g., at least one ostium of the Fallopian tubes accessed transvaginally and transcervically, to indicate delivery of an occlusion device into the corresponding at least one Fallopian tube to effect contraception are disclosed. Marking is effected by delivery of a dye that stains the ostium and/or extension of the marking member from the delivered occlusion device into view in the uterine cavity or ostium. A catheter (or catheters) preferably introduced through a hysteroscope that illuminates and provides visualization of the uterine cavity and the ostia of the Fallopian tubes is employed to insert each contracted, stent-like, occluding device into each Fallopian tube and to mechanically expand or release to self-expand the occluding device.
摘要翻译：公开了显着标记生殖道的系统和方法，例如经阴道和经腹腔进入的输卵管的至少一个口，以指示将闭塞装置输送到相应的至少一个输卵管中以实现避孕。通过递送将标记构件的口和/或延伸从递送的闭塞装置输送到子宫腔或口中的染色来实现标记。采用优选通过宫腔镜引入的导管（或导管）照亮并提供输卵管的子宫腔和口腔的可视化，以将每个收缩的支架样闭塞装置插入每个输卵管中并机械地扩张或释放自动扩张闭塞装置。

9. 发明申请

US20110130776A1 OCCLUSION DEVICE AND SYSTEM FOR OCCLUDING A REPRODUCTIVE BODY LUMEN 有权
标题翻译： OCCLUSION设备和系统，用于监护生殖器官
公开(公告)号：US20110130776A1
公开(公告)日：2011-06-02
申请号：US12991907
申请日：2009-05-18
申请人： Jose W. Jimenez , James R. Mujwid , William S. Tremulis , John R. Frigstad , Karl A. Jagger , Kevin R. Arnal , Jeffrey P. Callister
发明人： Jose W. Jimenez , James R. Mujwid , William S. Tremulis , John R. Frigstad , Karl A. Jagger , Kevin R. Arnal , Jeffrey P. Callister
IPC分类号： A61B17/08
CPC分类号： A61F6/005 , A61F6/06 , A61F6/22 , A61F6/225
摘要： A system and method of occluding a reproductive body lumen (34) to prevent the passage of reproductive cells through body lumen is disclosed. The system can include a catheter delivery system (10) having a handle device (18), a catheter (10) operatively coupled with the handle device (20), and an occluding device adapted for deployment within the body lumen. The handle device can include a damper device adapted to reduce the vibration on the handle device from deployment of the occluding device from the catheter. Further, the handle device can include an indexing member operatively coupled with the catheter to provide indexing of the catheter.
摘要翻译：公开了一种闭塞生殖体腔（34）以防止生殖细胞通过体腔通过的系统和方法。该系统可以包括具有手柄装置（18）的导管输送系统（10），与手柄装置（20）可操作地连接的导管（10）和适于部署在体腔内的闭塞装置。手柄装置可以包括阻尼器装置，其适于减少手柄装置上的振动，以避免将阻塞装置从导管部署。此外，手柄装置可以包括与导管可操作地连接以提供导管的分度的分度构件。

10. 发明申请

US20100168514A1 ENDOSCOPIC DELIVERY OF MEDICAL DEVICES 审中-公开
标题翻译：医疗器械内窥镜输送
公开(公告)号：US20100168514A1
公开(公告)日：2010-07-01
申请号：US12652006
申请日：2010-01-04
申请人： Jeffrey P. Callister , William S. Tremulis , Laura Kemp , Paul M. Stull
发明人： Jeffrey P. Callister , William S. Tremulis , Laura Kemp , Paul M. Stull
IPC分类号： A61F6/20 , A61F6/06
CPC分类号： A61B1/018 , A61B1/00082 , A61B1/00133 , A61B1/04 , A61B1/303 , A61B5/4839 , A61B17/12022 , A61B17/12172 , A61B17/12177 , A61B2017/1205 , A61B2017/12054 , A61B2017/4233 , A61B2090/037 , A61F6/225
摘要： The invention is directed to an endoscopic assembly having an endoscope, particularly a flexible hysteroscope and an outer sheath disposed about a length of the shaft of the hysteroscope which has an expandable member such as an inflatable balloon for sealing the assembly within a body lumen or cavity. Specifically, the endoscope assembly is configured for delivery of an occlusive contraceptive member to the patient's fallopian tube. The invention is also directed to an endoscope having a driving member for movement of a medical device within the working lumen of an endoscope. In one embodiment the driving member is a friction wheel which engages an elongated medical device disposed within the working channel of the endoscope to effect longitudinal movement of the medical device.
摘要翻译：本发明涉及具有内窥镜，特别是柔性宫腔镜的内窥镜组件和围绕宫腔镜的轴的长度设置的外护套，其具有可膨胀构件，例如可膨胀气囊，用于将组件密封在体腔或腔内。具体地，内窥镜组件构造成用于将闭塞性避孕构件输送到患者的输卵管。本发明还涉及具有用于在内窥镜的工作腔内移动医疗装置的驱动部件的内窥镜。在一个实施例中，驱动构件是摩擦轮，其接合设置在内窥镜的工作通道内的细长医疗装置，以实现医疗装置的纵向移动。

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