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1. 发明申请

US20110275916A1 Control solution packets and methods for calibrating bodily fluid sampling devices 审中-公开
标题翻译：控制溶液包和校准体液采样装置的方法
公开(公告)号：US20110275916A1
公开(公告)日：2011-11-10
申请号：US11153854
申请日：2005-06-15
申请人： Jeffrey N. Roe , Michael E. Hilgers , Jay Vinson , John H. Priest , Steven P. Mecca , Thomas C. Rademacher
发明人： Jeffrey N. Roe , Michael E. Hilgers , Jay Vinson , John H. Priest , Steven P. Mecca , Thomas C. Rademacher
IPC分类号： A61B5/145
CPC分类号： A61B5/157 , A61B5/14514 , A61B5/14532 , A61B5/150022 , A61B5/150175 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/15144 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T436/10 , Y10T436/102499 , Y10T436/103332 , Y10T436/104165 , Y10T436/104998 , Y10T436/105831 , Y10T436/106664 , Y10T436/109163
摘要： A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the container. The control solution can be pressurized before or during calibration so as to ensure the appropriate amount of control solution is delivered to the bodily fluid sampling device. The control solution is manufactured to have a viscosity that controls delivery of the control solution to the device. The membrane is permeable by a piercing device of the bodily fluid sampling device and seals around the piercing device during calibration. In another aspect, the container is in the form of a capsule or dosing attachment that contains the control solution along with a sponge-like material.
摘要翻译：用于校准体液采样装置的控制解决方案包包括容器，在容器内加压的对照溶液以及用于覆盖和密封容器的膜。在校准之前或期间，可以对对照溶液进行加压，以确保将适当量的对照溶液输送到体液采样装置。控制解决方案被制造成具有控制控制溶液输送到装置的粘度。该膜可通过体液采样装置的穿刺装置渗透，并在校准过程中围绕穿刺装置密封。在另一方面，容器是胶囊或剂量附件的形式，其包含对照溶液以及海绵状材料。

2. 发明授权

US07018848B2 Electrochemical test device and related methods 失效
公开(公告)号：US07018848B2
公开(公告)日：2006-03-28
申请号：US10224875
申请日：2002-08-21
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
IPC分类号： G01N33/551
CPC分类号： C12Q1/001 , C12Q1/004 , C12Q1/006 , Y10S435/817 , Y10S436/805 , Y10S436/806
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode. The test device electrodes can be constructed on a flexible film substrate, such as a polymeric film or a metal foil coated with a non-conductive coating.

3. 发明授权

US06582573B2 Membrane based electrochemical test device 失效
标题翻译：基于膜的电化学测试装置
公开(公告)号：US06582573B2
公开(公告)日：2003-06-24
申请号：US09878774
申请日：2001-06-08
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
IPC分类号： G01N27327
CPC分类号： C12Q1/001 , C12Q1/26 , G01N27/3272 , G01N33/54386
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode.
摘要翻译：提供电化学测试装置，用于确定含水流体样品中分析物的存在或浓度。电化学测试装置包括工作电极和由非晶半导体材料制成的对电极。工作电极与能够与分析物反应的试剂重叠，以产生可测量的电位变化，其可以与流体样品中分析物的浓度相关。测试装置可选地包含由在参考电极上具有参考材料的非晶半导体材料制成的参考电极。

4. 发明授权

US06245215B1 Membrane based electrochemical test device and related methods 失效
标题翻译：基于膜的电化学测试装置及相关方法
公开(公告)号：US06245215B1
公开(公告)日：2001-06-12
申请号：US09401062
申请日：1999-09-22
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
IPC分类号： G01N2726
CPC分类号： C12Q1/001 , C12Q1/26 , G01N27/3272 , G01N33/54386
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode.
摘要翻译：提供电化学测试装置，用于确定含水流体样品中分析物的存在或浓度。电化学测试装置包括工作电极和由非晶半导体材料制成的对电极。工作电极与能够与分析物反应的试剂重叠，以产生可测量的电位变化，其可以与流体样品中分析物的浓度相关。测试装置可选地包含由在参考电极上具有参考材料的非晶半导体材料制成的参考电极。

5. 发明授权

US07115362B2 Electrochemical test device and related methods 失效
公开(公告)号：US07115362B2
公开(公告)日：2006-10-03
申请号：US11287522
申请日：2005-11-23
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
IPC分类号： C12Q1/00
CPC分类号： C12Q1/001 , C12Q1/004 , C12Q1/006 , Y10S435/817 , Y10S436/805 , Y10S436/806
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode. The test device electrodes can be constructed on a flexible film substrate, such as a polymeric film or a metal foil coated with a non-conductive coating.

6. 发明授权

US6001239A Membrane based electrochemical test device and related methods 失效
公开(公告)号：US6001239A
公开(公告)日：1999-12-14
申请号：US164405
申请日：1998-09-30
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , David A. Hasker
IPC分类号： C12Q1/00 , C12Q1/26 , G01N33/487 , G01N33/49 , G01N33/543 , G01N27/26
CPC分类号： C12Q1/001 , C12Q1/26 , G01N27/3272 , G01N33/54386
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode.

7. 发明授权

US06750962B2 Optics alignment and calibration system 有权
标题翻译：光学对准和校准系统
公开(公告)号：US06750962B2
公开(公告)日：2004-06-15
申请号：US09828874
申请日：2001-04-10
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , John M. Gleisner , Charles C. Raney , David A. Hasker , Ryszard Radwanski , John Ramirez
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest , John M. Gleisner , Charles C. Raney , David A. Hasker , Ryszard Radwanski , John Ramirez
IPC分类号： G01N110
CPC分类号： G01N21/8483
摘要： A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.
摘要翻译：多用分析系统将包含LED，光电检测器和透镜或光管的光学系统的支撑试剂 - 分析物反应的可移除测试条准确地对准，以将光导向和从测试条引导。使用对准夹具实现对接，由此依靠光学块保持器将测试条和测试垫与各种光学部件对准。来自光电检测器的指示测试条反应进程的信号被提供给用于测量分析物的处理器。

8. 发明授权

US06638772B1 Electrochemical test device 失效
标题翻译：电化学试验装置
公开(公告)号：US06638772B1
公开(公告)日：2003-10-28
申请号：US08876812
申请日：1997-06-17
申请人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
发明人： Joel S. Douglas , Jeffrey N. Roe , John H. Priest
IPC分类号： G01N33543
CPC分类号： C12Q1/001 , C12Q1/004 , C12Q1/006 , Y10S435/817 , Y10S436/805 , Y10S436/806
摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode. The test device electrodes can be constructed on a flexible film substrate, such as a polymeric film or a metal foil coated with a non-conductive coating.
摘要翻译：提供电化学测试装置，用于确定含水流体样品中分析物的存在或浓度。电化学测试装置包括工作电极和由非晶半导体材料制成的对电极。工作电极与能够与分析物反应的试剂重叠，以产生可测量的电位变化，其可以与流体样品中分析物的浓度相关。测试装置可选地包含由在参考电极上具有参考材料的非晶半导体材料制成的参考电极。测试装置电极可以构建在柔性膜基底上，例如聚合物膜或涂有非导电涂层的金属箔。

9. 发明授权

US08123701B2 Methods and apparatus for sampling and analyzing body fluid 有权
标题翻译：体液取样分析方法及装置
公开(公告)号：US08123701B2
公开(公告)日：2012-02-28
申请号：US12779317
申请日：2010-05-13
申请人： Joel S. Douglas , Jeffrey N. Roe , Ryszard Radwanski , Brent G. Duchon
发明人： Joel S. Douglas , Jeffrey N. Roe , Ryszard Radwanski , Brent G. Duchon
IPC分类号： A61B5/00
CPC分类号： A61B10/0045 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150755 , A61B5/150824 , A61B5/151 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B2010/0003 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要： A sampling device for sampling body fluid includes a lancet for making an incision, a capillary tube for drawing-up body fluid from the incision, and a test strip affixed to an upper end of the capillary tube for receiving the fluid. An absorbent pad can be disposed between the test strip and capillary tube for spreading-out the fluid being transferred to the test strip. An onsite analyzer such as an optical analyzer and/or an electrochemical analyzer can be mounted in the device for analyzing the fluid. Alternatively, a test strip can be slid through a slot formed in the bottom end of the device so that by passing the device against the skin after an incision has been formed, the test strip will directly contact body fluid emanating from the incision.
摘要翻译：用于体液取样的采样装置包括用于切开的刺血针，用于从切口吸取体液的毛细管，以及固定到毛细管的上端以接收流体的测试条。可以在测试条和毛细管之间设置吸收垫，以便将被传送到测试条的流体展开。诸如光学分析仪和/或电化学分析仪的现场分析仪可以安装在用于分析流体的装置中。或者，测试条可以滑动通过形成在装置的底端的槽，使得通过在形成切口之后使装置抵靠皮肤，测试条将直接接触从切口发出的体液。

10. 发明授权

US07901363B2 Body fluid sampling device and methods of use 有权
标题翻译：体液取样装置及使用方法
公开(公告)号：US07901363B2
公开(公告)日：2011-03-08
申请号：US10753973
申请日：2004-01-08
申请人： Brent G. Duchon , Joel S. Douglas , Jeffrey N. Roe , Ryszard Radwanski , Andrew M. Drexler
发明人： Brent G. Duchon , Joel S. Douglas , Jeffrey N. Roe , Ryszard Radwanski , Andrew M. Drexler
IPC分类号： A61B5/00
CPC分类号： A61B10/0045 , A61B5/14532 , A61B5/150022 , A61B5/150152 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150717 , A61B5/150824 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/1519 , A61B5/15194 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要： A device for sampling body fluid includes a housing having a sleeve at a forward end thereof which is displaceable in response to being pressed against a user's skin to trigger the firing of a lancet. After the lancet is removed from the incision, the sleeve is repeatedly pressed against the skin to depress a ring of body tissue in surrounding relationship to the incision to express body fluid outwardly through the incision. A pusher member is then actuated to push a capillary tube through a front end of the housing for drawing-in body fluid. The lancet is a disposable lancet which includes a body supporting a skin-lancing member and the capillary tube. The disposable lancet passes through an upper end of a lancet carrier when being installed or removed. The device cannot be armed until the disposable lancet is installed in the housing, because the capillary tube functions to push a safety device to a non-safety position.
摘要翻译：用于体液取样的装置包括：壳体，其在其前端具有套筒，该壳体可响应于压靠使用者的皮肤而移位，以触发刺血针的点燃。在从切口中取出刺血针之后，套筒被重复地压在皮肤上，以与切口围绕的关系压下身体组织环，以通过切口向外表达体液。然后致动推动器构件以推动毛细管穿过壳体的前端以吸入体液。柳叶刀是一次性的柳叶刀，其包括支撑皮肤穿刺部件和毛细管的主体。当安装或拆卸时，一次性柳叶刀穿过柳叶刀托架的上端。由于毛细管的作用是将安全装置推到非安全位置，因此该装置将不会挂起，直到一次性的柳叶刀安装在外壳中。

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