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    • 7. 发明授权
    • Fungicidal pyrazoles
    • 杀真菌吡唑
    • US09062005B2
    • 2015-06-23
    • US13254205
    • 2010-03-03
    • Jeffrey Keith LongWonpyo HongAndrew Edmund Taggi
    • Jeffrey Keith LongWonpyo HongAndrew Edmund Taggi
    • C07D231/12C07D231/20C07D231/38C07D401/04C07D401/12C07D401/14C07D403/12C07D407/12C07D409/04C07D417/12
    • A01N43/56C07D231/12C07D231/20C07D231/38C07D401/04C07D401/12C07D401/14C07D403/12C07D407/12C07D409/04C07D417/12
    • Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein Q1 is a phenyl ring, naphthalenyl ring system, a 5- to 6-membered fully unsaturated heterocyclic ring or an 8- to 10-membered heteroaromatic bicyclic ring system, each as described with optional substituents as defined in the disclosure; Q2 is a phenyl ring, a naphthalenyl ring system, a 5- to 6-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring, or an 8- to 10-membered heteroaromatic bicyclic ring system, each as described with optional substituents as defined in the disclosure; X is O, S(O)m, NR4, CR15R16, C(═O) or C(═S); and R1, R1a, R2, R4, R15, R16 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention. Also disclosed are compounds of Formula 2, including all geometric and stereoisomers, and salts thereof, wherein X is NH; and Q1, Q2 and R2 are as defined for Formula 1; which are useful as intermediates for preparing compounds of Formula 1.
    • 公开了式1的化合物,包括所有几何和立体异构体,N-氧化物及其盐,其中Q1是苯环,萘环体系,5-至6-元完全不饱和杂环或8-至10- 每个如本公开中所定义的任选的取代基所述; Q2是苯环,萘环体系,5至6元饱和,部分不饱和或完全不饱和的杂环或8至10元杂芳族双环系统,每个如在如 披露; X是O,S(O)m,NR 4,CR 15 R 16,C(= O)或C(= S))。 并且R1,R1a,R2,R4,R15,R16和m如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法,包括施用有效量的本发明化合物或组合物。 还公开了式2的化合物,包括所有几何和立体异构体及其盐,其中X是NH; 且Q1,Q2和R2如式1所定义; 其可用作制备式1化合物的中间体。
    • 8. 发明申请
    • FUNGICIDAL PYRAZOLES
    • 真菌PYRAZOLES
    • US20110319430A1
    • 2011-12-29
    • US13254205
    • 2010-03-03
    • Jeffrey Keith LongWonpyo HongAndrew Edmund Taggi
    • Jeffrey Keith LongWonpyo HongAndrew Edmund Taggi
    • A01N43/56C07D231/20C07D401/12A01P3/00C07D403/12C07D231/12C07D401/06C07D231/38C07D401/04
    • A01N43/56C07D231/12C07D231/20C07D231/38C07D401/04C07D401/12C07D401/14C07D403/12C07D407/12C07D409/04C07D417/12
    • Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein Q1 is a phenyl ring, naphthalenyl ring system, a 5- to 6-membered fully unsaturated heterocyclic ring or an 8- to 10-membered heteroaromatic bicyclic ring system, each as described with optional substituents as defined in the disclosure; Q2 is a phenyl ring, a naphthalenyl ring system, a 5- to 6-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring, or an 8- to 10-membered heteroaromatic bicyclic ring system, each as described with optional substituents as defined in the disclosure; X is O, S(O)m, NR4, CR15R16, C(═O) or C(═S); and R1, R1a, R2, R4, R15, R16 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention. Also disclosed are compounds of Formula 2, including all geometric and stereoisomers, and salts thereof, wherein X is NH; and Q1, Q2 and R2 are as defined for Formula 1; which are useful as intermediates for preparing compounds of Formula 1.
    • 公开了式1的化合物,包括所有几何和立体异构体,N-氧化物及其盐,其中Q1是苯环,萘环体系,5-至6-元完全不饱和杂环或8-至10- 每个如本公开中所定义的任选的取代基所述; Q2是苯环,萘环体系,5至6元饱和,部分不饱和或完全不饱和的杂环或8至10元杂芳族双环系统,每个如在如 披露; X是O,S(O)m,NR 4,CR 15 R 16,C(= O)或C(= S))。 并且R1,R1a,R2,R4,R15,R16和m如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法,包括施用有效量的本发明化合物或组合物。 还公开了式2的化合物,包括所有几何和立体异构体及其盐,其中X是NH; 且Q1,Q2和R2如式1所定义; 其可用作制备式1化合物的中间体。
    • 10. 发明授权
    • Heterobicycle-substituted azolyl benzene fungicides
    • 异环取代的唑基苯类杀真菌剂
    • US08921360B2
    • 2014-12-30
    • US13500928
    • 2010-10-12
    • John Lawrence Andreassi, IIAndrew Edmund Taggi
    • John Lawrence Andreassi, IIAndrew Edmund Taggi
    • A01N43/50A01N43/647A01N43/32C07D265/36C07D231/02C07D405/04A01N43/56A01N47/18A01N47/28
    • C07D405/04A01N43/56A01N47/18A01N47/28
    • Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein Y is a 5-membered, fully or partially unsaturated heterocyclic ring containing 2-4 carbon atoms and 2-3 nitrogen atoms as ring members, the ring substituted with Z on a ring member atom connected through an adjacent single ring member atom to the ring member atom attaching the heterocyclic ring to the phenyl ring of Formula 1, and optionally further substituted with up to 2 substituents independently selected from R5 on carbon atom ring members and from R6 on nitrogen atom ring members; Z is an 8-, 9-, 10- or 11-membered fused heterobicyclic ring system containing ring members selected from carbon atoms and 1 to 4 heteroatoms independently selected from up to 2 O, up to 2 S and up to 4 N atoms, wherein up to 3 carbon atom ring members are independently selected from C(═O) and C(═S), and the sulfur atom ring members are independently selected from S(═O)u(═NR7)z, the ring system optionally substituted with substituents independently selected from R8 on carbon atom ring members and from R9 on nitrogen atom ring members; and R1, R2, R3, R4, R5, R6, R7, R8, R9, u and z are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
    • 公开了式1的化合物,包括所有的立体异构体,N-氧化物及其盐,其中Y是含有2-4个碳原子和2-3个氮原子作为环成员的5元全部或部分不饱和的杂环, 在通过相邻单环原子连接的环成员原子上被Z取代的环与连接杂环的环原子连接到式1的苯环上,并且任选被至多2个独立地选自在碳原子上的R5的取代基取代 环成员和R6上的氮原子环成员; Z是含有选自碳原子和1至4个独立地选自至多2个,至多2个和至多4个N原子的1至4个杂原子的环成员的8-,9-,10-或11-元稠合杂双环体系, 其中最多3个碳原子环成员独立地选自C(= O)和C(= S),并且硫原子环成员独立地选自S(= O)u(= NRR)z, 被取代基独立地选自碳原子环上的R 8和氮原子环上的R 9; 并且R1,R2,R3,R4,R5,R6,R7,R8,R9,u和z如本公开所定义。 还公开了含有式1化合物的组合物和用于控制由真菌病原体引起的植物病害的方法,包括施用有效量的本发明化合物或组合物。