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1. 发明授权

US10385367B2 Methods and molecules for yield improvement involving metabolic engineering 有权
公开(公告)号：US10385367B2
公开(公告)日：2019-08-20
申请号：US13322383
申请日：2010-06-01
申请人： Jeffrey C. Way , Joseph H. Davis
发明人： Jeffrey C. Way , Joseph H. Davis
IPC分类号： C12N1/00 , C12N5/00 , C12P13/00 , C12P13/04 , C12P7/42 , C12N9/12 , C12N15/10 , C12N15/67
摘要： The invention features methods and compositions relating to cells that have been engineered to reduce or eliminate proteins having enzymatic activity that interfere with the expression of a metabolic product.

2. 发明申请

US20120070870A1 Methods and Molecules for Yield Improvement Involving Metabolic Engineering 审中-公开
标题翻译：涉及代谢工程产量改善的方法与分子
公开(公告)号：US20120070870A1
公开(公告)日：2012-03-22
申请号：US13322383
申请日：2010-06-01
申请人： Jeffrey C. Way , Joseph H. Davis
发明人： Jeffrey C. Way , Joseph H. Davis
IPC分类号： C12P7/64 , C12N9/12 , C12P7/16 , C12P7/42 , C12P7/56 , C12N9/00 , C12N9/06
CPC分类号： C12P7/42 , C07K2319/95 , C12N9/1205 , C12N15/10 , C12N15/67
摘要： The invention features methods and compositions relating to cells that have been engineered to reduce or eliminate proteins having enzymatic activity that interfere with the expression of a metabolic product.
摘要翻译：本发明的特征在于与已被工程化以减少或消除干扰代谢产物表达的具有酶活性的蛋白质相关的细胞的方法和组合物。

3. 发明授权

US5921347A Folding saw horse system 失效
标题翻译：折叠锯马系统
公开(公告)号：US5921347A
公开(公告)日：1999-07-13
申请号：US915749
申请日：1997-08-21
申请人： Oswaldo Rodriguez , Joseph H. Davis
发明人： Oswaldo Rodriguez , Joseph H. Davis
IPC分类号： B25H1/06 , F16M11/00
CPC分类号： B25H1/06
摘要： A new Folding Saw Horse System for facilitating a portable lightweight work aide which allows the user to adjust the work area height, and for providing a compact storage design which is sturdy and stable when expanded. The inventive device includes an elongated support beam, a secured pair of legs secured to one side of the elongated support beam and a folding pair of legs pivotally attached to the secured pair of legs and engaging the elongated support beam on the side opposite of the secured pair of legs when in the expanded position.
摘要翻译：一种新的折叠锯马系统，便于便携式轻便的工作助手，使用户能够调整工作区域的高度，并提供紧凑的存储设计，在扩展时坚固稳定。本发明的装置包括细长的支撑梁，固定在细长支撑梁的一侧上的固定的一对腿和可枢转地附接到固定的一对腿的折叠对的腿，并且将细长支撑梁与固定的支撑梁相对的一侧处于展开位置的双腿。

4. 发明授权

US4544078A Sealed closure for sealing and closing an opening in a container 失效
标题翻译：用于密封和关闭容器中的开口的密封闭合件
公开(公告)号：US4544078A
公开(公告)日：1985-10-01
申请号：US613048
申请日：1984-05-22
申请人： Alvaro Arenas , John W. Box , Joseph H. Davis , Harshad Tataria
发明人： Alvaro Arenas , John W. Box , Joseph H. Davis , Harshad Tataria
IPC分类号： H01M2/04 , H01M2/30 , H01M2/36 , B65D51/18
CPC分类号： H01M2/361 , H01M2/0426 , H01M2/30 , H01M2/365
摘要： The method for closing and sealing the opening of a wall of a container includes the steps of: providing the opening with a counterbore; inserting a first plug member into said opening in a fluid tight manner to establish a first seal; inserting a second plug member into said counterbore and above said first plug member and said opening; and fixing and sealing said second plug member to said wall around said counterbore so that a fluid tight second seal is formed between said second plug member and said wall thereby to provide a double seal for preventing leakage of fluid material from said container through said opening.The fluid tight closure assembly is adapted to provide a fluid tight closure for closing and sealing the opening in the wall of the container having fluid material therein. The closure assembly includes a first plug member which is inserted into the opening in the wall of the container in a fluid tight manner to establish a first seal, the opening being provided with a counterbore. The plug assembly further includes a second plug member which is adapted to be inserted into the counterbore above the first plug member and the opening. The second plug member is permanently fixed to the wall around the counterbore in a fluid tight manner so that a fluid tight second seal is formed between the second plug member and the wall thereby to provide a double seal for preventing leakage of fluid material from the container through the opening.
摘要翻译：关闭和密封容器壁的开口的方法包括以下步骤：向开口提供沉孔; 以流体密封的方式将第一塞子构件插入所述开口中以建立第一密封; 将第二塞子构件插入所述沉孔中，并在所述第一塞构件和所述开口之上; 以及将所述第二塞构件固定和密封到围绕所述沉孔的所述壁上，使得在所述第二塞构件和所述壁之间形成流体密封的第二密封，从而提供双重密封，以防止流体材料从所述容器穿过所述开口泄漏。流体密封闭合组件适于提供流体密封的封闭件，用于封闭和密封容器壁上的开口，其中具有流体材料。闭合组件包括第一插塞构件，其以流体密封的方式插入容器的壁中的开口中以建立第一密封，该开口设置有沉孔。插塞组件还包括第二插塞构件，其适于插入第一插塞构件和开口上方的沉孔中。第二塞子构件以流体密封的方式永久地固定到沉孔周围的壁上，使得在第二塞子构件和壁之间形成流体密封的第二密封，从而提供双重密封，以防止流体材料从容器泄漏通过开放。

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