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1. 发明授权

US08128699B2 Spinal implant and methods of implantation and treatment 有权
标题翻译：脊柱植入物和植入和治疗方法
公开(公告)号：US08128699B2
公开(公告)日：2012-03-06
申请号：US12403585
申请日：2009-03-13
申请人： Jeff R. Justis , Hai H. Trieu , Dimitri K. Protopsaltis , Jeffrey H. Nycz
发明人： Jeff R. Justis , Hai H. Trieu , Dimitri K. Protopsaltis , Jeffrey H. Nycz
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61F2/441 , A61F2002/30014 , A61F2002/30393 , A61F2002/30428 , A61F2002/30433 , A61F2002/3052 , A61F2002/30546 , A61F2002/30548 , A61F2002/30563 , A61F2002/30586 , A61F2002/30596 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2002/30904 , A61F2002/30906 , A61F2002/30925 , A61F2002/3093 , A61F2002/484 , A61F2002/485 , A61F2002/5004 , A61F2220/0025 , A61F2220/0041 , A61F2250/0012 , A61F2250/0013 , A61F2250/0018 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00161 , A61F2310/00167 , A61F2310/00179 , A61F2310/00203 , A61F2310/00239 , A61F2310/00796
摘要： A spinal implant is provided that includes a first component for engaging a first vertebra, a second component for engaging a second vertebrae, and a damping member is positioned therebetween. The damping member has at least two chambers connected by an opening. A fluid is disposed within the chambers such that compression of the first and second components towards one another causes the fluid to be displaced from one of the chambers to another chamber through an opening. The opening has a reduced size relative to the chambers to restrict the flow of the fluid between the chambers and provide a dampening effect. In some instances, the rheologic properties of the fluid positioned within the chambers are dependent upon the strength a magnetic field passing through the fluid. In other aspects of the present disclosure, prosthetic devices, intervertebral implants, spinal systems, implantation methods, and treatment methods are provided.
摘要翻译：提供了一种脊柱植入物，其包括用于接合第一椎骨的第一部件，用于接合第二椎骨的第二部件，以及位于其间的阻尼部件。阻尼构件具有通过开口连接的至少两个室。流体设置在室内，使得第一和第二部件相对于彼此的压缩导致流体通过开口从一个室移动到另一个室。开口相对于腔室具有减小的尺寸，以限制腔室之间的流体流动并提供阻尼效果。在一些情况下，位于室内的流体的流变特性取决于磁场通过流体的强度。在本公开的其他方面，提供了假体装置，椎间植入物，脊柱系统，植入方法和治疗方法。

2. 发明申请

US20110270262A1 Systems, Devices and Methods for Bending an Elongate Member 有权
标题翻译：用于弯曲细长构件的系统，设备和方法
公开(公告)号：US20110270262A1
公开(公告)日：2011-11-03
申请号：US12770921
申请日：2010-04-30
申请人： Jeff R. Justis , Dimitri K. Protopsaltis , Hai H. Trieu
发明人： Jeff R. Justis , Dimitri K. Protopsaltis , Hai H. Trieu
IPC分类号： A61B17/58
CPC分类号： A61B17/8863 , A61B17/7013
摘要： Systems, devices and methods are provided for bending an elongate member used in a medical procedure. In one form, the device includes a bending mechanism having a plurality of engaging members are selectively positioned relative to a receiving area. In one embodiment, a first set of engaging members is positioned in a select arrangement, and a second set of the engaging members is movable relative to the select arrangement of the first set of engaging members to compressingly engage the elongate member to bend the elongate member to a desired shape/contour. The device also includes a heating element configured to apply heat to one or more portions of the elongate member to facilitate bending. In one form, the elongate member is formed of a heat deformable material, and heat is applied to soften one or more portions of the elongate member to provide added flexibility to facilitate bending.
摘要翻译：提供了用于弯曲在医疗过程中使用的细长构件的系统，装置和方法。在一种形式中，该装置包括具有多个接合构件的弯曲机构，其相对于接收区域选择性地定位。在一个实施例中，第一组接合构件定位在选择装置中，并且第二组接合构件可相对于第一组接合构件的选择装置移动，以压缩地接合细长构件以使细长构件到期望的形状/轮廓。该装置还包括加热元件，该加热元件被配置为对细长构件的一个或多个部分施加热量以便于弯曲。在一种形式中，细长构件由热变形材料形成，并且施加热量以软化细长构件的一个或多个部分以提供增加的柔性以便于弯曲。

3. 发明授权

US08632524B2 Injectable biocompatible material delivery system 有权
标题翻译：注射生物相容材料输送系统
公开(公告)号：US08632524B2
公开(公告)日：2014-01-21
申请号：US11471993
申请日：2006-06-21
申请人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
IPC分类号： A61K9/22 , A61F2/28
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译：公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。

4. 发明申请

US20100234954A1 SPINAL IMPLANT AND METHODS OF IMPLANTATION AND TREATMENT 有权
标题翻译：脊柱植入物和植入和治疗方法
公开(公告)号：US20100234954A1
公开(公告)日：2010-09-16
申请号：US12403585
申请日：2009-03-13
申请人： Jeff R. Justis , Hai H. Trieu , Dimitri K. Protopsaltis , Jeffrey H. Nycz
发明人： Jeff R. Justis , Hai H. Trieu , Dimitri K. Protopsaltis , Jeffrey H. Nycz
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61F2/441 , A61F2002/30014 , A61F2002/30393 , A61F2002/30428 , A61F2002/30433 , A61F2002/3052 , A61F2002/30546 , A61F2002/30548 , A61F2002/30563 , A61F2002/30586 , A61F2002/30596 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2002/30904 , A61F2002/30906 , A61F2002/30925 , A61F2002/3093 , A61F2002/484 , A61F2002/485 , A61F2002/5004 , A61F2220/0025 , A61F2220/0041 , A61F2250/0012 , A61F2250/0013 , A61F2250/0018 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00161 , A61F2310/00167 , A61F2310/00179 , A61F2310/00203 , A61F2310/00239 , A61F2310/00796
摘要： A spinal implant is provided that includes a first component for engaging a first vertebra, a second component for engaging a second vertebrae, and a damping member is positioned therebetween. The damping member has at least two chambers connected by an opening. A fluid is disposed within the chambers such that compression of the first and second components towards one another causes the fluid to be displaced from one of the chambers to another chamber through an opening. The opening has a reduced size relative to the chambers to restrict the flow of the fluid between the chambers and provide a dampening effect. In some instances, the rheologic properties of the fluid positioned within the chambers are dependent upon the strength a magnetic field passing through the fluid. In other aspects of the present disclosure, prosthetic devices, intervertebral implants, spinal systems, implantation methods, and treatment methods are provided.
摘要翻译：提供了一种脊柱植入物，其包括用于接合第一椎骨的第一部件，用于接合第二椎骨的第二部件，以及位于其间的阻尼部件。阻尼构件具有通过开口连接的至少两个室。流体设置在室内，使得第一和第二部件相对于彼此的压缩导致流体通过开口从一个室移动到另一个室。开口相对于腔室具有减小的尺寸，以限制腔室之间的流体流动并提供阻尼效果。在一些情况下，位于室内的流体的流变特性取决于磁场通过流体的强度。在本公开的其他方面，提供了假体装置，椎间植入物，脊柱系统，植入方法和治疗方法。

5. 发明申请

US20070299426A1 Injectable biocompatible material delivery system 有权
标题翻译：注射生物相容材料输送系统
公开(公告)号：US20070299426A1
公开(公告)日：2007-12-27
申请号：US11471993
申请日：2006-06-21
申请人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
IPC分类号： A61K9/22 , A61M5/142
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译：公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。

6. 发明申请

US20080167686A1 Non-Rigid Intervertebral Spacers 审中-公开
标题翻译：非刚性椎间孔
公开(公告)号：US20080167686A1
公开(公告)日：2008-07-10
申请号：US11620364
申请日：2007-01-05
申请人： Hai H. Trieu , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Dimitri K. Protopsaltis
IPC分类号： A61F2/44 , A61B17/70
CPC分类号： A61F2/442 , A61F2002/2835 , A61F2002/30156 , A61F2002/30166 , A61F2002/30546 , A61F2002/30563 , A61F2002/30571 , A61F2002/30841 , A61F2002/30884 , A61F2002/30892 , A61F2002/30906 , A61F2002/30925 , A61F2002/4475 , A61F2002/448 , A61F2230/0023 , A61F2230/0028 , A61F2250/0012 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00796 , A61F2310/00976
摘要： An intervertebral spacer includes a non-rigid body having an upper beam member and a lower beam member. The upper beam member may include a lower inner surface and may include an upper outer surface configured to interface with a vertebral plate of an upper vertebra. The lower beam member may include an upper inner surface and may include a lower outer surface configured to interface with a vertebral plate of a lower vertebra. The upper inner surface of the lower beam member and the lower inner surface of the upper beam member may define an oval-shaped hollow portion.
摘要翻译：椎间间隔物包括具有上梁构件和下梁构件的非刚性体。上梁构件可以包括下内表面，并且可以包括构造成与上椎骨的椎板相接合的上外表面。下梁构件可以包括上内表面，并且可以包括被配置成与下椎骨的椎板相接合的下外表面。下梁构件的上内表面和上梁构件的下内表面可以限定椭圆形的中空部分。

7. 发明申请

US20100198261A1 ADJUSTABLE SPINAL STABILIZATION SYSTEMS 审中-公开
标题翻译：可调脊柱稳定系统
公开(公告)号：US20100198261A1
公开(公告)日：2010-08-05
申请号：US12757123
申请日：2010-04-09
申请人： Hai H. Trieu , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Dimitri K. Protopsaltis
IPC分类号： A61B17/70 , A61B17/88
CPC分类号： A61B17/7004 , A61B17/701 , A61B17/7014
摘要： A spinal stabilization system includes a stabilization member with opposite end portions lying along a longitudinal axis and an adjustment mechanism between the end portions that allows the end portions to be moved toward and away from one another along the longitudinal axis.
摘要翻译：脊柱稳定系统包括稳定构件，其具有沿着纵向轴线的相对端部和在端部之间的调节机构，其允许端部沿着纵向轴线彼此移动并远离彼此。

8. 发明授权

US08911480B2 Non-metallic implant devices and intra-operative methods for assembly and fixation 有权
标题翻译：非金属植入装置和术中用于组装和固定的方法
公开(公告)号：US08911480B2
公开(公告)日：2014-12-16
申请号：US13097622
申请日：2011-04-29
申请人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
发明人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
IPC分类号： A61B17/88 , A61B17/80 , A61B17/86 , A61B17/70 , A61B17/00 , A61F2/08
CPC分类号： A61B17/8042 , A61B17/7059 , A61B17/8052 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61F2/0811
摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.
摘要翻译：本发明涉及矫形植入物和治疗骨缺损的方法。更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

9. 发明授权

US08480718B2 Curable orthopedic implant devices configured to be hardened after placement in vivo 有权
标题翻译：固定的整形外科植入物装置被配置成在放置在体内之后硬化
公开(公告)号：US08480718B2
公开(公告)日：2013-07-09
申请号：US11643187
申请日：2006-12-21
申请人： Dimitri Protopsaltis , Hai H. Trieu , Jeff R. Justis , Michael C. Sherman
发明人： Dimitri Protopsaltis , Hai H. Trieu , Jeff R. Justis , Michael C. Sherman
IPC分类号： A61B17/84 , A61F2/44 , A61B17/80 , A61B17/70
CPC分类号： A61B17/866 , A61B17/7013 , A61B17/7032 , A61B17/7049 , A61B17/80 , A61B17/8605 , A61B17/8625 , A61B17/8836 , A61F2/441 , A61F2/4425 , A61F2/4455 , A61F2/4465 , A61F2/447 , A61F2002/2835 , A61F2002/30062 , A61F2002/302 , A61F2002/30225 , A61F2002/30545 , A61F2002/30556 , A61F2002/30583 , A61F2002/30677 , A61F2002/30884 , A61F2002/3092 , A61F2002/444 , A61F2002/4495 , A61F2002/465 , A61F2210/0004 , A61F2210/0085 , A61F2230/0065 , A61F2230/0069 , A61F2250/0009 , A61F2250/001
摘要： Orthopedic implants include a device that is non-rigid, i.e., flexible and/or malleable, in a first form for insertion into a desired in vivo site, and then transformable into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material. Related methods and kits are also provided.
摘要翻译：矫形植入物包括非刚性的，即柔性的和/或有延展性的装置，其以第一形式插入到期望的体内部位，然后可变形成刚性或硬化的形式，以提供承载功能或在植入后提供其他结构和/或机械功能。该装置包括生物相容护套和密封在护套内的可固化材料。可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。还提供了相关方法和试剂盒。

10. 发明授权

US07951177B2 Non-metallic implant devices and intra-operative methods for assembly and fixation 有权
标题翻译：非金属植入装置和术中用于组装和固定的方法
公开(公告)号：US07951177B2
公开(公告)日：2011-05-31
申请号：US11703059
申请日：2007-02-06
申请人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
发明人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
IPC分类号： A61B17/80
CPC分类号： A61B17/8042 , A61B17/7059 , A61B17/8052 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61F2/0811
摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.
摘要翻译：本发明涉及矫形植入物和治疗骨缺损的方法。更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

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