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1. 发明授权

US06579243B2 Catheter with thermal sensor for detection of vulnerable plaque 有权
公开(公告)号：US06579243B2
公开(公告)日：2003-06-17
申请号：US09797400
申请日：2001-03-01
申请人： Jaydeep Y. Kokate , Eric M. DoBrava , Suzana Prstic , Scott Kimmell , Marwane S. Berrada , Avram Bar-Cohen , Michael Hoey
发明人： Jaydeep Y. Kokate , Eric M. DoBrava , Suzana Prstic , Scott Kimmell , Marwane S. Berrada , Avram Bar-Cohen , Michael Hoey
IPC分类号： A61B500
CPC分类号： A61M29/02 , A61B5/015 , A61B5/6853 , A61M25/0084 , A61M25/0147 , A61M25/104 , A61M2025/0089 , A61M2205/3368
摘要： Methods and devices for detecting vulnerable plaque within a blood vessel are disclosed. An elongate medical device in accordance with the present invention includes an elongate shaft having a proximal end and a distal end. A substrate is fixed to the elongate shaft proximate the distal end thereof, and a plurality of sensors are disposed on the substrate. Each sensor is preferably coupled to a switching device. The switching devices are preferably disposed on the substrate.

2. 发明申请

US20220105342A1 ANATOMICAL/PHYSIOLOGICAL EVENT APPARATUS AND METHOD OF TREATING AN APPROACHING 有权
公开(公告)号：US20220105342A1
公开(公告)日：2022-04-07
申请号：US17421864
申请日：2020-01-10
申请人： Jeffrey Bennett , Michael Hoey , Shawn McCutcheon
发明人： Jeffrey Bennett , Michael Hoey , Shawn McCutcheon
IPC分类号： A61N1/36 , A61N1/04
摘要： A neuromodulation device and method capable of varying a neuromodulation therapy in order to prevent, delay or control a sexual emission.

3. 发明授权

US10390873B2 Systems and methods for prostate treatment 有权
公开(公告)号：US10390873B2
公开(公告)日：2019-08-27
申请号：US12843581
申请日：2010-07-26
申请人： Michael Hoey , John H. Shadduck
发明人： Michael Hoey , John H. Shadduck
IPC分类号： A61B18/04 , A61B18/08 , A61B18/00
摘要： An energy delivery probe is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply energy to tissue, such as a prostrate, to shrink, damage, denaturate the prostate. In some embodiments, the energy can be applied with a vapor media. The energy delivery probe can include a vapor delivery member configured to extend into a transition zone prostate tissue. A condensable vapor media can be delivered from the vapor delivery member into the transition zone tissue, wherein the condensable vapor media can propagate interstitially in the transition zone tissue and be confined in the transition zone tissue by boundary tissue adjacent to the transition zone tissue. Methods associated with use of the energy delivery probe are also covered.

4. 发明授权

US08579888B2 Medical probes for the treatment of blood vessels 失效
标题翻译：用于治疗血管的医疗探针
公开(公告)号：US08579888B2
公开(公告)日：2013-11-12
申请号：US12486702
申请日：2009-06-17
申请人： Michael Hoey , John H. Shadduck
发明人： Michael Hoey , John H. Shadduck
IPC分类号： A61B18/18 , A61B18/04 , A61B19/00
CPC分类号： A61F7/12 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00243 , A61B2017/22051 , A61B2018/00011 , A61B2018/1861 , A61F2/95
摘要： Devices and methods for thermally-mediated treatment of blood vessels to elicit an immune response to cause rapid endothelial growth over at least portions of an implant or stent to prevent adverse events such as restenosis. Devices and methods for thermally-mediated treatment to inhibit contraction of vessels to elicit an immune response to cause rapid endothelial growth over at least portions of a stent to prevent adverse events such as restenosis.
摘要翻译：用于热介导治疗血管以引发免疫应答以在植入物或支架的至少部分上引起快速内皮生长以防止不良事件例如再狭窄的装置和方法。用于热介导治疗以抑制血管收缩以引发免疫应答以在支架的至少部分上引起快速内皮生长以防止不良事件例如再狭窄的装置和方法。

5. 发明授权

US08187269B2 Medical instruments and techniques for treating pulmonary disorders 有权
标题翻译：用于治疗肺部疾病的医疗仪器和技术
公开(公告)号：US08187269B2
公开(公告)日：2012-05-29
申请号：US12947228
申请日：2010-11-16
申请人： John H. Shadduck , Michael Hoey
发明人： John H. Shadduck , Michael Hoey
IPC分类号： A61B18/18
CPC分类号： A61B18/04 , A61B17/32037 , A61B2017/00809 , A61B2018/00315 , A61B2018/048
摘要： A surgical instrument for delivering energy to lung tissue, for example to cause lung volume reduction. In one embodiment, an elongated catheter has a handle portion that includes an interior chamber that is supplied with a biocompatible liquid media under pressure. An energy source delivers energy to the media to cause a liquid-to-vapor phase change within the interior chamber and ejects a flow of vapor media from the working end of the catheter. The delivery of energy and the flow of vapor are controlled by a computer controller to cause a selected pressure and selected volume of vapor to propagate to the extremities of the airways. Contemporaneously, the vapor undergoes a vapor-to-liquid phase transition which delivers large amount of energy to the airway tissue. The thermal energy delivered is equivalent to the heat of vaporization of the fluid media, which shrinks and collapses the treated airways. The treated tissue is the maintained in a collapsed state by means of aspiration for a short interval to enhance tissue remodeling. Thereafter, the patient's wound healing response causes fibrosis and further remodeling to cause permanent lung volume reduction.
摘要翻译：用于向肺组织递送能量的手术器械，例如以减少肺容积。在一个实施例中，细长导管具有手柄部分，该手柄部分包括在压力下供应生物相容性液体介质的内部腔室。能量源将能量传递到介质以在内部室内引起液体 - 气相变化，并从导管的工作端喷出蒸气介质流。能量的传递和蒸气的流动由计算机控制器控制，以使所选压力和选定体积的蒸气传播到气道的末端。同时，蒸气经历气 - 液相转移，其向气道组织输送大量的能量。传递的热能相当于流体介质的蒸发热量，这会使经过处理的气道收缩和收缩。经处理的组织通过抽吸短时间保持在折叠状态以增强组织重塑。此后，患者的伤口愈合反应引起纤维化并进一步重塑以造成永久肺容积减少。

6. 发明申请

US20100145325A1 Systems and Methods for Treatment of Prostatic Tissue 有权
标题翻译：前列腺组织治疗系统与方法
公开(公告)号：US20100145325A1
公开(公告)日：2010-06-10
申请号：US12614218
申请日：2009-11-06
申请人： Michael Hoey , John H. Shadduck
发明人： Michael Hoey , John H. Shadduck
IPC分类号： A61B18/08
CPC分类号： A61B18/04 , A61B18/082 , A61B18/14 , A61B2018/00017 , A61B2018/00029 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/048 , A61B2018/1472 , A61B2034/2063 , A61B2218/002 , A61B2218/007
摘要： A prostate therapy system is provided that may include any of a number of features. One feature of the prostate therapy system is that it can access a prostate lobe transurethrally. Another feature of the prostate therapy system is that it can deliver condensable vapor into the prostate to ablate the prostate tissue. Methods associated with use of the prostate therapy system are also covered.
摘要翻译：提供了可以包括多个特征中的任何一个的前列腺治疗系统。前列腺治疗系统的一个特点是可以经尿道前列腺进入前列腺。前列腺治疗系统的另一个特征是它可以将可冷凝的蒸气输送到前列腺中以消融前列腺组织。还涉及与使用前列腺治疗系统相关的方法。

7. 发明申请

US20100071626A1 System and method of detecting disease in mammal 审中-公开
标题翻译：检测哺乳动物疾病的系统和方法
公开(公告)号：US20100071626A1
公开(公告)日：2010-03-25
申请号：US12460479
申请日：2009-07-20
申请人： Michael Hoey
发明人： Michael Hoey
IPC分类号： A01J5/007 , A01J5/16
摘要： Mastitis in a milking animal is detected through sensing the capacitance effects in milk. Using frequencies of greater than 60 megahertz applied by a capacitance probe to milk as it streams through otherwise conventional milking equipment during milking, yields a reliably discernable shift in the phase angle, indicating the presence of mastitis.
摘要翻译：通过感测牛奶中的电容效应来检测挤奶动物的乳腺炎。使用大于60兆赫兹的频率由电容探头施加，以便在挤奶过程中通过其他常规挤奶设备流动时，可以产生可靠地辨别的相位角位移，表明存在乳腺炎。

8. 发明申请

US20080103497A1 METHOD AND APPARATUS FOR CREATING A BI-POLAR VIRTUAL ELECTRODE USED FOR THE ABLATION OF TISSUE 审中-公开
标题翻译：用于创建用于组织组织的双极虚拟电极的方法和装置
公开(公告)号：US20080103497A1
公开(公告)日：2008-05-01
申请号：US11966769
申请日：2007-12-28
申请人： PETER MULIER , Michael Hoey
发明人： PETER MULIER , Michael Hoey
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/1482 , A61B2018/00005 , A61B2018/00053 , A61B2018/00291 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/126 , A61B2018/1472 , A61B2218/002 , A61B2218/007
摘要： A method and apparatus for creating a virtual electrode to ablate bodily tissue. The apparatus includes an outer tube, a first electrode, an inner tube and a second electrode. The outer tube is fluidly connected to a source of conductive fluid and defines a proximal end and a distal end. The distal end includes an opening for delivering conductive fluid from the outer tube. The first electrode is disposed at the distal end of the outer tube for applying a current to conductive fluid delivered from the outer tube. The inner tube is coaxially received within the outer tube and is connected to a source of conductive fluid. The inner tube defines a proximal end and a distal end, with the distal end forming an opening for delivering conductive fluid from the inner tube. Finally, the second electrode is disposed at the distal end of the inner tube for applying a current to conductive fluid delivered from the inner tube. With this configuration, upon final assembly, the distal end of the outer tube is axially spaced from the distal end of the inner tube such that the first electrode is spaced from the second electrode. As a result, a bi-polar virtual electrode can be established.
摘要翻译：一种用于产生虚拟电极以消除身体组织的方法和装置。该装置包括外管，第一电极，内管和第二电极。外管流体地连接到导电流体源并且限定近端和远端。远端包括用于从外管输送导电流体的开口。第一电极设置在外管的远端，用于向从外管输送的导电流体施加电流。内管同轴地容纳在外管内并连接到导电流体源。内管限定近端和远端，远端形成用于从内管输送导电流体的开口。最后，第二电极设置在内管的远端，用于向从内管传送的导电流体施加电流。利用该构造，在最终组装时，外管的远端与内管的远端轴向间隔开，使得第一电极与第二电极间隔开。结果，可以建立双极虚拟电极。

9. 发明申请

US20080015563A1 APPARATUS AND METHOD FOR CREATING, MAINTAINING, AND CONTROLLING A VIRTUAL ELECTRODE USED FOR THE ABLATION OF TISSUE 审中-公开
标题翻译：用于创建，维护和控制用于消除组织的虚拟电极的装置和方法
公开(公告)号：US20080015563A1
公开(公告)日：2008-01-17
申请号：US11782134
申请日：2007-07-24
申请人： Michael Hoey , Mark Christopherson , Steven Goetz
发明人： Michael Hoey , Mark Christopherson , Steven Goetz
IPC分类号： A61N1/00
CPC分类号： A61B18/18 , A61B18/1206 , A61B18/1233 , A61B18/14 , A61B18/1402 , A61B18/1815 , A61B2018/00029 , A61B2018/00196 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1213 , A61B2018/1253 , A61B2018/1417 , A61B2018/1472 , A61B2018/1475 , A61B2218/002 , A61B2218/007
摘要： An apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current. An apparatus in accord with the present disclosure includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present disclosure includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.
摘要翻译：一种在用射频交流电流处理的组织内或之上产生虚拟电极的装置和方法。根据本公开的装置包括提供要提供给患者的导电或电解液，交流发生器和用于通过间隔或表面递送的产生，维持和控制消融过程的处理器流体到组织并经由虚拟电极向组织递送电力。根据本公开的方法包括将导电流体递送到预定组织消融部位预定时间段，向组织施加预定功率水平的射频电流，监测几个参数中的至少一个，并且调整响应于测量的参数施加的功率和/或流体流量。

10. 发明申请

US20070093808A1 Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue 审中-公开
标题翻译：用于创建用于组织消融的双极虚拟电极的方法和装置
公开(公告)号：US20070093808A1
公开(公告)日：2007-04-26
申请号：US11636331
申请日：2006-12-08
申请人： Peter Mulier , Michael Hoey
发明人： Peter Mulier , Michael Hoey
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/1482 , A61B2018/00005 , A61B2018/00053 , A61B2018/00291 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/126 , A61B2018/1472 , A61B2218/002 , A61B2218/007
摘要： A method and apparatus for creating a virtual electrode to ablate bodily tissue. The apparatus includes an outer tube, a first electrode, an inner tube and a second electrode. The outer tube is fluidly connected to a source of conductive fluid and defines a proximal end and a distal end. The distal end includes an opening for delivering conductive fluid from the outer tube. The first electrode is disposed at the distal end of the outer tube for applying a current to conductive fluid delivered from the outer tube. The inner tube is coaxially received within the outer tube and is connected to a source of conductive fluid. The inner tube defines a proximal end and a distal end, with the distal end forming an opening for delivering conductive fluid from the inner tube. Finally, the second electrode is disposed at the distal end of the inner tube for applying a current to conductive fluid delivered from the inner tube. With this configuration, upon final assembly, the distal end of the outer tube is axially spaced from the distal end of the inner tube such that the first electrode is spaced from the second electrode. As a result, a bi-polar virtual electrode can be established.
摘要翻译：一种用于产生虚拟电极以消除身体组织的方法和装置。该装置包括外管，第一电极，内管和第二电极。外管流体地连接到导电流体源并且限定近端和远端。远端包括用于从外管输送导电流体的开口。第一电极设置在外管的远端，用于向从外管输送的导电流体施加电流。内管同轴地容纳在外管内并连接到导电流体源。内管限定近端和远端，远端形成用于从内管输送导电流体的开口。最后，第二电极设置在内管的远端，用于向从内管传送的导电流体施加电流。利用该构造，在最终组装时，外管的远端与内管的远端轴向间隔开，使得第一电极与第二电极间隔开。结果，可以建立双极虚拟电极。

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