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1. 发明申请

US20130301046A1 SYSTEMS HAVING A REFLECTED LIGHT SENSOR AND METHODS OF USE 有权
标题翻译：具有反射光传感器的系统及其使用方法
公开(公告)号：US20130301046A1
公开(公告)日：2013-11-14
申请号：US13471341
申请日：2012-05-14
申请人： Janyce Lipson
发明人： Jan Lipson , Donald A. Ice , Rudolf J. Hofmeister , Yuxin Zhou , Harold G. Sampson , Qingfeng Huang , James Stewart
IPC分类号： G01J3/42 , H01L27/146 , G01J1/44
CPC分类号： G01J3/021 , G01J1/32 , G01J3/0297 , G01J3/10 , H01L27/14601 , H01L27/14806
摘要： Various systems and methods of monitoring laser safety by sensing contact of the system with a sample are provided. The system includes a focusing element for focusing an incident light from a laser light source onto a sample, an optical element having a collection zone for collecting a signal from the sample, a reflected light sensor for sensing a reflected light from the sample, wherein the reflected light sensor is located outside the collection zone of the optical element and on an inner surface of a housing of the system, an electrical circuit operably connected to the reflected light sensor and the laser light source and configured to control power to the laser light source in accordance with the reflected light sensed by the reflected light sensor and a spectral analyzer for processing the signal. Methods and other systems are also described and illustrated.
摘要翻译：提供了通过感测系统与样品的接触来监测激光器安全性的各种系统和方法。该系统包括用于将来自激光源的入射光聚焦到样本上的聚焦元件，具有用于收集来自样品的信号的收集区域的光学元件，用于感测来自样品的反射光的反射光传感器，其中，反射光传感器位于光学元件的收集区域的外部并且位于系统的壳体的内表面上，可操作地连接到反射光传感器和激光源并被配置为控制激光源的功率的电路根据由反射光传感器感测的反射光和用于处理信号的光谱分析器。还描述和示出了方法和其他系统。

2. 发明授权

US08953160B2 Systems having a reflected light sensor and methods of use 有权
标题翻译：具有反射光传感器和使用方法的系统
公开(公告)号：US08953160B2
公开(公告)日：2015-02-10
申请号：US13471341
申请日：2012-05-14
申请人： Donald A. Ice , Rudolf J. Hofmeister , Yuxin Zhou , Harold G. Sampson , Qingfeng Huang , James Stewart , Janyce Lipson
发明人： Jan Lipson , Donald A. Ice , Rudolf J. Hofmeister , Yuxin Zhou , Harold G. Sampson , Qingfeng Huang , James Stewart
IPC分类号： G01J3/28
CPC分类号： G01J3/021 , G01J1/32 , G01J3/0297 , G01J3/10 , H01L27/14601 , H01L27/14806
摘要： Various systems and methods of monitoring laser safety by sensing contact of the system with a sample are provided. The system includes a focusing element for focusing an incident light from a laser light source onto a sample, an optical element having a collection zone for collecting a signal from the sample, a reflected light sensor for sensing a reflected light from the sample, wherein the reflected light sensor is located outside the collection zone of the optical element and on an inner surface of a housing of the system, an electrical circuit operably connected to the reflected light sensor and the laser light source and configured to control power to the laser light source in accordance with the reflected light sensed by the reflected light sensor and a spectral analyzer for processing the signal. Methods and other systems are also described and illustrated.
摘要翻译：提供了通过感测系统与样品的接触来监测激光器安全性的各种系统和方法。该系统包括用于将来自激光源的入射光聚焦到样本上的聚焦元件，具有用于收集来自样品的信号的收集区域的光学元件，用于感测来自样品的反射光的反射光传感器，其中，反射光传感器位于光学元件的收集区域的外部和系统的壳体的内表面上，可操作地连接到反射光传感器和激光光源并被配置为控制激光源的功率的电路根据由反射光传感器感测的反射光和用于处理信号的光谱分析器。还描述和示出了方法和其他系统。

3. 发明申请

US20120320375A1 Apparatus for Stabilizing Mechanical, Thermal, and Optical Properties and for Reducing the Fluorescence of Biological Samples for Optical Evaluation 有权
标题翻译：用于稳定机械，热和光学性能并用于减少用于光学评估的生物样品的荧光的装置
公开(公告)号：US20120320375A1
公开(公告)日：2012-12-20
申请号：US13160412
申请日：2011-06-14
申请人： Jan Lipson , Jeffrey M. Bernhardt , Robert P. McNamara , Rudolf J. Hofmeister , Donald A. Ice , Janyce Lipson
发明人： Jan Lipson , Jeffrey M. Bernhardt , Robert P. McNamara , Rudolf J. Hofmeister , Donald A. Ice , Janyce Lipson
IPC分类号： G01N21/01
CPC分类号： G01N21/01
摘要： An apparatus is presented for stabilizing an optical, thermal, and mechanical interface between a spectroscopic and/or imaging system and a biological sample. The apparatus includes a window retainer having a retainer surface and a well. The retainer surface surrounds the well. Further, the retainer surface is substantially planar. An optical window is located in the well. The optical window comprises a first and second surface. The second surface is in contact with the window retainer. The first surface is substantially flush with the retainer surface. The apparatus further includes an attachment mechanism coupling the window retainer to the biological sample such that a fluid, gel, adhesive or elastomer interposed between the optical window and the biological sample is trapped in the well.
摘要翻译：提出了用于稳定光谱和/或成像系统与生物样品之间的光学，热学和机械界面的装置。该装置包括具有保持器表面和井的窗口保持器。保持器表面围绕井。此外，保持器表面基本上是平面的。光学窗口位于井中。光学窗口包括第一和第二表面。第二表面与窗口保持器接触。第一表面与保持器表面基本齐平。该装置还包括将窗口保持器联接到生物样本的附接机构，使得插入光学窗口和生物样品之间的流体，凝胶，粘合剂或弹性体被捕获在孔中。

4. 发明授权

US08411265B2 Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation 有权
标题翻译：用于稳定机械，热和光学性质并用于降低生物样品的荧光以进行光学评估的装置
公开(公告)号：US08411265B2
公开(公告)日：2013-04-02
申请号：US13160412
申请日：2011-06-14
申请人： Jeffrey M. Bernhardt , Robert P. McNamara , Rudolf J. Hofmeister , Donald A. Ice , Janyce Lipson
发明人： Jan Lipson , Jeffrey M. Bernhardt , Robert P. McNamara , Rudolf J. Hofmeister , Donald A. Ice
IPC分类号： G01N21/01 , G01N1/10
CPC分类号： G01N21/01
摘要： An apparatus is presented for stabilizing an optical, thermal, and mechanical interface between a spectroscopic and/or imaging system and a biological sample. The apparatus includes a window retainer having a retainer surface and a well. The retainer surface surrounds the well. Further, the retainer surface is substantially planar. An optical window is located in the well. The optical window comprises a first and second surface. The second surface is in contact with the window retainer. The first surface is substantially flush with the retainer surface. The apparatus further includes an attachment mechanism coupling the window retainer to the biological sample such that a fluid, gel, adhesive or elastomer interposed between the optical window and the biological sample is trapped in the well.
摘要翻译：提出了用于稳定光谱和/或成像系统与生物样品之间的光学，热学和机械界面的装置。该装置包括具有保持器表面和井的窗口保持器。保持器表面围绕井。此外，保持器表面基本上是平面的。光学窗口位于井中。光学窗口包括第一和第二表面。第二表面与窗口保持器接触。第一表面与保持器表面基本齐平。该装置还包括将窗口保持器联接到生物样本的附接机构，使得插入光学窗口和生物样品之间的流体，凝胶，粘合剂或弹性体被捕获在孔中。

5. 发明申请

US20110194183A1 Apparatus For Enhancing Scattered Light Detection By Re-Directing Scattered Light Outside The Angular Range Of Collection Optics Back To The Sample And Method Of Fabricating Same 审中-公开
标题翻译：用于通过将散射光重新定向在收集光学的角度范围内来增强散射光检测的装置返回到制造相同的样品和方法
公开(公告)号：US20110194183A1
公开(公告)日：2011-08-11
申请号：US13021004
申请日：2011-02-04
申请人： Jan Lipson , Janyce Lipson , Rudolf J. Hofmeister , Donald A. Ice , Sascha Hallstein
发明人： Jan Lipson , Janyce Lipson , Rudolf J. Hofmeister , Donald A. Ice , Sascha Hallstein
IPC分类号： G02B17/08 , G02B5/08 , G02B1/11 , G02B5/10 , B24B1/00
CPC分类号： B24B1/00 , B24B11/00 , B24B13/015 , G02B27/0018
摘要： An apparatus comprising an optical window transmits both an excitation beam to a sample and scattered light from the sample which is within the angular range of the collection optics. Scattered light from the sample outside the angular range of the collection optics is re-directed back to the sample by reflection from one or more surfaces of the apparatus. As a result, the magnitude of scattered light collected is increased.
摘要翻译：包括光学窗口的装置将激发光束与样品和来自样品的来自收集光学器件的角度范围内的散射光传输。来自收集光学器件角度范围之外的样品的散射光通过从装置的一个或多个表面的反射被重新引导回样品。结果，收集的散射光的大小增加。

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