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1. 发明授权

US07315763B2 Cochlear implant electrode and method of making same 有权
标题翻译：人工耳蜗植入电极及其制作方法
公开(公告)号：US07315763B2
公开(公告)日：2008-01-01
申请号：US10666465
申请日：2003-09-19
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara , Steven A. Hazard
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara , Steven A. Hazard
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61N1/36036
摘要： A cochlear stimulation lead having a pre-curved electrode array is provided. The molding process provides memory to the curved part of the lead. The lead may be made having a stylet insertion channel that extends from a slightly curved or substantially straight section and into the highly curved section of the lead. Because high compliance is desired for the lead in cochlear stimulation applications, the compliance is controlled not only by the taper at the distal end of the lead and overall lead thickness, but also by choosing the material hardness of the lead carrier/covering and employing compliant zigzagged conductor wire. In addition, differential lead compliance/stiffness can be achieved by using a stiff tubing that forms part of the stylet insertion channel.
摘要翻译：提供具有预弯曲电极阵列的耳蜗刺激引线。模制过程为铅的弯曲部分提供记忆。引线可以制成具有从略微弯曲或基本上直的部分延伸到引线的高度弯曲部分的探针插入通道。由于耳蜗刺激应用中的铅需要高度依从性，所以顺应性不仅受铅的远端的锥度和整体铅厚度的控制，而且还通过选择引线载体/覆盖物的材料硬度并采用顺应性曲折导线。此外，通过使用形成探针插入通道的一部分的硬管可以实现差动引线顺从/刚度。

2. 发明申请

US20110276118A1 Cochlear Implant Electrode and Method of Making Same 有权
标题翻译：人工耳蜗电极及其制作方法
公开(公告)号：US20110276118A1
公开(公告)日：2011-11-10
申请号：US13103927
申请日：2011-05-09
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61N1/36036 , Y10T29/49117
摘要： A cochlear stimulation lead and method of making a curved electrode array are provided. In one embodiment of the lead, while the curved section of the lead is curled further beyond its originally molded curvature and held in this position, a filling channel is filled with a filling material that is hardened or cured in this held position. The resulting lead has a tip curvature that is more curved than the originally molded curvature.
摘要翻译：提供了一种人工耳蜗刺激引线和制作弯曲电极阵列的方法。在引线的一个实施例中，当引线的弯曲部分被卷曲进一步超出其初始模制曲率并保持在该位置时，填充通道填充有在该保持位置被硬化或固化的填充材料。所得到的引线具有比最初模制曲率更弯曲的尖端曲率。

3. 发明授权

US08280528B2 Implantable cochlear lead 有权
标题翻译：植入式耳蜗导线
公开(公告)号：US08280528B2
公开(公告)日：2012-10-02
申请号：US13103927
申请日：2011-05-09
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenawara
IPC分类号： A61N1/00
CPC分类号： A61N1/0541 , A61N1/36036 , Y10T29/49117
摘要： A cochlear stimulation lead and method of making a curved electrode array are provided. In one embodiment of the lead, while the curved section of the lead is curled further beyond its originally molded curvature and held in this position, a filling channel is filled with a filling material that is hardened or cured in this held position. The resulting lead has a tip curvature that is more curved than the originally molded curvature.
摘要翻译：提供了一种人工耳蜗刺激引线和制作弯曲电极阵列的方法。在引线的一个实施例中，当引线的弯曲部分被卷曲进一步超出其初始模制曲率并保持在该位置时，填充通道填充有在该保持位置被硬化或固化的填充材料。所得到的引线具有比最初模制曲率更弯曲的尖端曲率。

4. 发明授权

US07941228B2 Cochlear implant electrode and method of making same 有权
标题翻译：人工耳蜗植入电极及其制作方法
公开(公告)号：US07941228B2
公开(公告)日：2011-05-10
申请号：US11870301
申请日：2007-10-10
申请人： Janusz A. Kuzma , Chuladatta Thenawara , Lani A. Smith
发明人： Janusz A. Kuzma , Chuladatta Thenawara , Lani A. Smith
IPC分类号： A61N1/00
CPC分类号： A61N1/0541 , A61N1/36036 , Y10T29/49117
摘要： A cochlear stimulation lead and method of making a curved electrode array are provided. In one embodiment of the lead, while the curved section of the lead is curled further beyond its originally molded curvature and held in this position, a filling channel is filled with a filling material that is hardened or cured in this held position. The resulting lead has a tip curvature that is more curved than the originally molded curvature.
摘要翻译：提供了一种人工耳蜗刺激引线和制作弯曲电极阵列的方法。在引线的一个实施例中，当引线的弯曲部分被卷曲进一步超出其初始模制曲率并保持在该位置时，填充通道填充有在该保持位置被硬化或固化的填充材料。所得到的引线具有比最初模制曲率更弯曲的尖端曲率。

5. 发明授权

US08538554B2 Implantable electrode, insertion tool for use therewith, and insertion method 有权
标题翻译：可植入电极，与其一起使用的插入工具和插入方法
公开(公告)号：US08538554B2
公开(公告)日：2013-09-17
申请号：US12212427
申请日：2008-09-17
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenuwara , Tom Xiaohai He
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenuwara , Tom Xiaohai He
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61B17/3468 , A61N1/05 , A61N1/0558
摘要： An electrode system includes an implantable electrode having at least one electrode contact, an insertion tool, and a technique or method that allows the electrode contact to be positioned within soft tissue at a selected target stimulation site.
摘要翻译：电极系统包括具有至少一个电极接触的可植入电极，插入工具以及允许电极接触位于选定的目标刺激部位的软组织内的技术或方法。

6. 发明申请

US20090240258A1 DETACHABLE HANDLE FOR IMPLANTABLE ELECTRICAL STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 审中-公开
标题翻译：用于可植入电刺激系统的可拆卸手柄及其制造和使用方法
公开(公告)号：US20090240258A1
公开(公告)日：2009-09-24
申请号：US12406885
申请日：2009-03-18
申请人： Janusz A. Kuzma , Anne Margaret Pianca , Lani A. Smith
发明人： Janusz A. Kuzma , Anne Margaret Pianca , Lani A. Smith
IPC分类号： A61B17/00
CPC分类号： A61N1/056 , A61B2017/00469
摘要： A detachable handle includes a handle body that is substantially tubular and defines a hollow center region extending at least a portion of a longitudinal length of the handle body. The handle body is configured and arranged to receive a portion of a stylet handle within the hollow center region and removably attach to the stylet handle. The handle body includes an external gripping surface extending at least a portion of an exterior surface of the handle body.
摘要翻译：可拆卸手柄包括手柄主体，该手柄主体基本上是管状的并且限定了延伸至手柄主体的纵向长度的至少一部分的中空中心区域。手柄主体被构造和布置成接收在中空中心区域内的探针手柄的一部分并且可移除地附接到探针手柄。手柄本体包括延伸手柄主体的外表面的至少一部分的外部夹持表面。

7. 发明授权

US06757970B1 Method of making multi-contact electrode array 有权
标题翻译：制造多接触电极阵列的方法
公开(公告)号：US06757970B1
公开(公告)日：2004-07-06
申请号：US10000408
申请日：2001-11-02
申请人： Janusz A. Kuzma , William Vanbrooks Harrison , Lani A. Smith
发明人： Janusz A. Kuzma , William Vanbrooks Harrison , Lani A. Smith
IPC分类号： H05K302
CPC分类号： A61N1/0529 , A61N1/0551 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： A multicontact electrode array suitable for implantation in living tissue includes a distal end having multiple spaced-apart ring contacts or a pattern of spaced-apart electrode contacts carried on a flexible carrier. Each electrode contact is resistance welded to a respective wire that is wound helically inside a silicon tube. The center of the helix defines a lumen wherein a positioning stylet, or other suitable positioning tool, may be removably inserted when the electrode array is implanted. The electrode array is made using a method that includes, as an initial step, winding lead wires around a suitable mandrel forming a helix configuration. Next, a non-conductive silicone tube jacket is placed around the wound wires, exposing the distal lead ends of the wires at a distal end of the tube. A welding process is then used to bond each wire tip to a corresponding metal electrode contact which has been preassembled by resistance welding to a metal foil structural carrier. The electrode array, including the metal foil structural carrier, is then formed into a tube by drawing it through a die. The excess foil material at the distal tip is then trimmed and a heat-shrink tube is placed around the assembled foil tube to prevent leakage of the polymer filler material through the joining longitudinal line of the carrier. Next, the foil tube is injected with a polymer filler material to void any gaps between the lead wires and contacts. To avoid filling the central lumen with the polymer filler material, a central core or stylet is temporarily placed inside the lumen. The heat-shrink tube is then mechanically removed. The fabrication method is finalized by inserting the preassembled electrode array into a hot acid mixture, which etches away the metal foil carrier, exposing the contacts at the surface of a distal end of the electrode array.
摘要翻译：适于植入生物组织的多电极电极阵列包括具有多个间隔开的环形触点的远端或承载在柔性载体上的间隔开的电极触点的图案。每个电极接触件被电阻焊接到螺旋形地缠绕在硅管内的相应导线。螺旋的中心限定了内腔，其中当植入电极阵列时可以可移除地插入定位探针或其它合适的定位工具。电极阵列使用包括作为初始步骤的方法包围围绕形成螺旋结构的适当心轴的引线。接下来，将不导电的硅胶管夹套放置在缠绕的线周围，将导线的远端引线末端暴露在管的远端。然后使用焊接工艺将每个焊丝尖端粘合到已经通过电阻焊接预先组装到金属箔结构载体上的对应的金属电极接触。包括金属箔结构载体的电极阵列然后通过将其拉伸通过模头而形成管。然后修剪远侧末端处的多余的箔材料，并且将热收缩管放置在组装的箔管周围，以防止聚合物填充材料通过载体的接合纵向线泄漏。接下来，箔管注入聚合物填充材料以去除引线和触点之间的任何间隙。为了避免用聚合物填充材料填充中央内腔，中心芯或探针被临时放置在管腔内。然后机械地去除热收缩管。通过将预组装的电极阵列插入热酸混合物来完成制造方法，所述热酸混合物蚀刻掉金属箔载体，暴露电极阵列远端表面处的触点。

8. 发明授权

US07805202B2 Implantable electrodes and insertion methods and tools 有权
标题翻译：可植入电极和插入方法和工具
公开(公告)号：US07805202B2
公开(公告)日：2010-09-28
申请号：US11241158
申请日：2005-09-30
申请人： Janusz A. Kuzma , Todd Kevin Whitehurst , Lani A. Smith , Chuladatta Thenuwara
发明人： Janusz A. Kuzma , Todd Kevin Whitehurst , Lani A. Smith , Chuladatta Thenuwara
IPC分类号： A61N1/02
CPC分类号： A61N1/0551 , A61N1/0529 , A61N1/0553
摘要： An insertion kit for implanting an electrode in a patient can include a handle; an insertion member coupled to the handle at a proximal end of the insertion member and configured and arranged to be inserted into a patient; an alignment member coupled to the handle and disposed over the distal end of the insertion member; and an electrode configured and arranged to be inserted into the patient using the insertion member. In some instances, the insertion kit may also include one or more of a marker that cooperates with the alignment member to mark a position of the electrode on the skin of the patient; a pointer that cooperates with the alignment member to find the marked position on the skin of the patient; and a second electrode and a second insertion member configured and arranged for detachably coupling to the handle in place of the insertion member.
摘要翻译：用于将电极植入患者体内的插入套件可以包括手柄; 插入构件，其在所述插入构件的近端处联接到所述手柄并且被配置和布置成插入到患者体内; 对准构件，其联接到所述手柄并设置在所述插入构件的远端上方; 以及电极，其构造和布置成使用插入构件插入到患者体内。在一些情况下，插入套件还可以包括与对准构件配合以标记电极在患者皮肤上的位置的标记物中的一个或多个; 与对准构件协作以在患者皮肤上找到标记位置的指针; 以及第二电极和第二插入构件，其构造和布置成可替代所述插入构件可拆卸地联接到所述手柄。

9. 发明申请

US20090024196A1 IMPLANTABLE ELECTRODE, INSERTION TOOL FOR USE THEREWITH, AND INSERTION METHOD 有权
标题翻译：可插入电极，插入工具及其插入方法
公开(公告)号：US20090024196A1
公开(公告)日：2009-01-22
申请号：US12212427
申请日：2008-09-17
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenuwara , Tom Xiaohai He
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladatta Thenuwara , Tom Xiaohai He
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61B17/3468 , A61N1/05 , A61N1/0558
摘要： An electrode system includes an implantable electrode having at least one electrode contact, an insertion tool, and a technique or method that allows the electrode contact to be positioned within soft tissue at a selected target stimulation site.
摘要翻译：电极系统包括具有至少一个电极接触的可植入电极，插入工具以及允许电极接触位于选定的目标刺激部位的软组织内的技术或方法。

10. 发明授权

US07460913B2 Implantable electrode, insertion tool for use therewith, and insertion method 有权
标题翻译：可植入电极，与其一起使用的插入工具和插入方法
公开(公告)号：US07460913B2
公开(公告)日：2008-12-02
申请号：US11124843
申请日：2005-05-09
申请人： Janusz A. Kuzma , Lani A. Smith , Chuladdatta Tehnuwara , Tom Xiaohai He
发明人： Janusz A. Kuzma , Lani A. Smith , Chuladdatta Tehnuwara , Tom Xiaohai He
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61B17/3468 , A61N1/05 , A61N1/0558
摘要： An electrode system includes an implantable electrode having at least one electrode contact, an insertion tool, and a technique or method that allows the electrode contact to be positioned within soft tissue at a selected target stimulation site.
摘要翻译：电极系统包括具有至少一个电极接触的可植入电极，插入工具以及允许电极接触位于选定的目标刺激部位的软组织内的技术或方法。

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