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    • 3. 发明授权
    • Medical device with expandable body for drug delivery by capsules
    • 具有可扩张体的医疗装置,用于通过胶囊药物递送
    • US08366661B2
    • 2013-02-05
    • US12953698
    • 2010-11-24
    • Jan WeberSteven P. Mertens
    • Jan WeberSteven P. Mertens
    • A61M31/00
    • A61M25/0074A61M2025/0057A61M2025/0681
    • Medical devices using an expandable body to deliver a therapeutic agent. In one particular embodiment, the medical device comprises a tubular catheter and an inner expandable body (e.g., a scaffolding) contained within the catheter. The inner expandable body is connected to a core wire for advancing or retracting the inner body. The inner body may be advanced to exit out of the catheter or retracted to withdraw the inner body back into the catheter. This particular embodiment further comprises a sheath on the outside of the interior of the catheter. The sheath carries a plurality of capsules that contain a therapeutic agent. The therapeutic agent is delivered by pushing the core wire to advance the inner body, which expands against the sheath, causing the capsules on the sheath to be compressed against body tissue such that the therapeutic agent is released.
    • 使用可膨胀体递送治疗剂的医疗装置。 在一个特定实施例中,医疗装置包括管状导管和包含在导管内的内部可膨胀体(例如,支架)。 内部可膨胀体连接到芯线以使内部物体前进或缩回。 内体可以被推进以离开导管或缩回以使内部体返回到导管中。 该特定实施例还包括在导管内部的外侧的护套。 鞘包含多个含有治疗剂的胶囊。 通过推动芯线来递送治疗剂以推进内部体,其抵靠护套膨胀,导致护套上的胶囊被压迫身体组织,使得治疗剂被释放。