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1. 发明授权

US4196216A Novel benzylidene amini-oxyalkyl carboxylic acids and carboxylic acid derivatives 失效
标题翻译：新型亚苄基氨基烷氧基烷基羧酸和羧酸衍生物
公开(公告)号：US4196216A
公开(公告)日：1980-04-01
申请号：US847765
申请日：1977-11-02
申请人： Jan Van Dijk , Volkert Claassen , Johannes M. A. Zwagemakers
发明人： Jan Van Dijk , Volkert Claassen , Johannes M. A. Zwagemakers
IPC分类号： A61K31/165 , A61K31/24 , A61K31/15 , C07C103/75
CPC分类号： A61K31/165 , A61K31/24
摘要： Certain nuclear substituted benzylidene amino oxyalkyl carboxylic acids esters, amides and salts thereof have been found to have a strong anti-inflammatory activity and a potent analgetic activity. In addition, some of the compounds have an activity against Rhino virus. An example is [(4-chlorobenzylideneamino)oxy] acetic acid.
摘要翻译：已经发现某些核取代的亚苄基氨基氧烷基羧酸酯，其酰胺和盐具有强的抗炎活性和强效的止痛活性。另外，一些化合物具有抗犀牛病毒的活性。一个例子是[（4-氯亚苄基氨基）氧基]乙酸。

2. 发明授权

US4889849A Spasmolytically active tertiary amine derivatives 失效
标题翻译：分解活性的叔胺衍生物
公开(公告)号：US4889849A
公开(公告)日：1989-12-26
申请号：US294997
申请日：1989-01-09
申请人： Ineke Van Wijngaarden , Johannes M. A. Zwagemakers , Jan Van Dijk
发明人： Ineke Van Wijngaarden , Johannes M. A. Zwagemakers , Jan Van Dijk
IPC分类号： C07D211/46 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/455 , C07D211/32 , C07D211/58 , C07D211/62 , C07D295/18 , C07D295/194
CPC分类号： C07D295/194 , C07D211/32 , C07D211/58
摘要： The invention relates to new spasmolytically active tertiary amine derivatives and the salts thereof, of the formula (1) ##STR1## wherein the symbols have the following meanings: .circle.A is phenyl, or a 5- or 6-membered aromatic group containing 1 or 2 of the following hetero atoms: oxygen and/or sulphur and/or nitrogen;R.sub.1 and R.sub.2 may be equal or different and are hydrogen or substituents;R.sub.3 is a hydrogen atom or, together with R.sub.4, may form a ring consisting of 6 or 7 carbon atoms;R.sub.4 is a hydrogen atom or alkyl group having 1-3 carbon atoms;R.sub.5 is a straight, branched or cyclic alkyl group having 1-4 carbon atoms;R.sub.6 is a straight or branched, saturated or unsaturated alkylene group having a chain length of 2-6 carbon atoms;Z is the group NR.sub.12, wherein R.sub.12 is a hydrogen atom or an alkyl group having 1-3 carbon atoms, or Z is an oxygen atom;n has the value 0 or 1;X is a carbonyl group, thiocarbonyl group or SO.sub.2 group;R.sub.7 and R.sub.8, together with the nitrogen atom to which they are bound, constitute a fully or partly saturated heterocyclic ring consisting of 5-8 ring atoms and which may comprise in addition an O, N or S-atom as the second hetero atom, and may be substituted.
摘要翻译：本发明涉及式（1）的新的解压活性叔胺衍生物及其盐，其中符号具有以下含义：＆amp; A是苯基或5-或6-元芳基含有1或2个以下杂原子：氧和/或硫和/或氮; R 1和R 2可以相同或不同，为氢或取代基; R3是氢原子，或者与R4一起可以形成由6或7个碳原子组成的环; R4是氢原子或具有1-3个碳原子的烷基; R5是具有1-4个碳原子的直链，支链或环状烷基; R6是链长2-6个碳原子的直链或支链饱和或不饱和亚烷基; Z是NR12基团，其中R12是氢原子或具有1-3个碳原子的烷基，或Z是氧原子; n的值为0或1; X是羰基，硫代羰基或SO2基团; R7和R8与它们所结合的氮原子一起构成由5-8个环原子组成的完全或部分饱和的杂环，并且另外可以包含作为第二杂原子的O，N或S-原子，并且可以被替代。

3. 发明授权

US5266589A Method of increasing the muscle/fat ratio in agricultural domestic animals 失效
标题翻译：增加农业家畜的肌肉/脂肪比例的方法
公开(公告)号：US5266589A
公开(公告)日：1993-11-30
申请号：US795386
申请日：1991-11-21
申请人： Johan K. Van Dasler , Jan Van Dijk
发明人： Johan K. Van Dasler , Jan Van Dijk
IPC分类号： A23K1/16 , A61K31/135 , A61K31/38 , A61K31/18
CPC分类号： A61K31/135 , A23K20/111 , A23K20/121
摘要： The invention relates to a method of improving the growth and the feed efficiency and of increasing the muscle/fat ratio of agricultural domestic animals, in particular bovine animals and sheep, by administering to the animals a composition which comprises as an active substance a compound of the general formula ##STR1## wherein: R.sub.1 is a phenylalkyl group the alkyl group of which comprises 1-3 carbon atoms and the phenyl group of which may be substituted with one or more substituents selected from the group consisting of hydroxy, methoxy, fluoro and methylsulphonylamino, or whereinR.sub.1 is a thienyl alkyl group or a tetrahydrofurylalkyl group the alkyl group of which comprises 1-3 carbon atoms; or whereinR.sub.1 is an optionally branched alkyl group having 1-8 carbon atoms which optionally is substituted with a C.sub.1 -C.sub.4 alkoxy group, a hydroxy group, a C.sub.1 -C.sub.4 alkoxycarbonyl group or a carboxy group; and whereinR.sub.2 and R.sub.3 are each independently methyl or ethyl; or an acid addition salt of the said compound.The invention further relates to a composition, in particular intended as a feed additive, which comprises such a phenylalkylamino derivative as an active substance.

4. 发明授权

US5023192A Method of manufacturing a bipolar transistor 失效
标题翻译：制造双极晶体管的方法
公开(公告)号：US5023192A
公开(公告)日：1991-06-11
申请号：US582298
申请日：1990-09-13
申请人： Wilhelmus J. Josquin , Jan Van Dijk
发明人： Wilhelmus J. Josquin , Jan Van Dijk
IPC分类号： H01L29/73 , H01L21/331 , H01L21/60 , H01L29/732
CPC分类号： H01L21/76897 , H01L29/66272 , Y10S148/043
摘要： A first device region (20) of one conductivity type is provided adjacent one major surface (11) of a semiconductor body (10). A layer (30) doped with impurities of the opposite conductivity type is provided on the one major surface (11) for forming an extrinsic subsidiary region (41) of a second device region (40) of the opposite conductivity type. An opening (31) is formed through the doped layer (30). Impurities for forming a coupling region (43) of the opposite conductivity type are introduced through the opening (31) prior to defining an insulating first portion (50) on the side wall (32) of the doped layer (30) to form a first window (80). Impurities for forming an intrinsic subsidiary region (42) of the second device region (40) are introduced through the first window (80). A second portion (60) is then defined on the insulating first portion (50) to form a smaller second window (90), and impurities for forming a third device region (70) through the second window (90) so that the extrinsic subsidiary region (41) and third device region are well spaced whilst the coupling region (43) enables good connection between the extrinsic and intrinsic subsidiary regions (41 and 42).

5. 发明授权

US3937841A Treatment of depression 失效
标题翻译：治疗呕吐
公开(公告)号：US3937841A
公开(公告)日：1976-02-10
申请号：US517519
申请日：1974-10-24
申请人： Jan Van Dijk , Jenkins Eric Davies
发明人： Jan Van Dijk , Jenkins Eric Davies
IPC分类号： C07C271/16 , C07D215/12 , C07D317/58 , C07D319/18 , A61K31/15 , A61K31/36 , A61K31/39 , A61K31/44 , A61K31/54
CPC分类号： C07D317/58 , C07C271/16 , C07D215/12 , C07D319/18 , C07C2103/18
摘要： The invention relates to new compounds of formula I ##SPC1##and salts thereof with pharmaceutically acceptable acids, in which formula all the substituents may be hydrogen, while R.sub.1 and R.sub.2 may furthermore be a methyl group, R.sub.3 an alkyl group, an alkoxy-alkylene group, an alkylthioalkylene group, an alkylsulphoxyalkylene group or an alkylsulphonalkylene group having up to 8 carbon atoms or a benzyl group, and R.sub.4, R.sub.5 and R.sub.6 a halogen atom, an alkyl group, an alkoxy group or an alkylthio group having up to 6 carbon atoms, a benzyloxy group, --OH, --NH.sub.2, a mono- or dialkylamino group, in which the alkyl group(s) contain(s) 1 or 2 carbon atoms, --CN or --CF.sub.3, and two of the substituents R.sub.4, R.sub.5 and R.sub.6 may each represent a metanitro group or together a trimethylene group, a tetramethylene group, a methylene dioxy group, an ethylene dioxy group, a benzo group, a pyridino group, an indeno-1,2-, a 1,4-benzthiazino-2,3 group or a 1,4-benzoxthiino-2,3 group, with the exception of the HCl salt of the compound in which R.sub.5 and R.sub.6 each represent an orthochlorine atom and R.sub. 1, R.sub.2, R.sub.3 and R.sub.4 each represent hydrogen.

6. 植物专利

USPP18644P3 Anthurium plant named ‘Anthepedi’ 有权
标题翻译：安祖花植物名为“Anthepedi”
公开(公告)号：USPP18644P3
公开(公告)日：2008-03-25
申请号：US11482613
申请日：2006-07-07
申请人： Jan Van Dijk
发明人： Jan Van Dijk
IPC分类号： A01H5/00
CPC分类号： A01H5/02
摘要： A new Anthurium plant particularly distinguished by red, durable spathes that slowly turn brown with age, dark-green, compact, durable leaves, medium-long erect peduncle, more inflorescences than leaves, rich shoot formation, flowers early and freely throughout the year, a compact and full plant habit with a plant height around 30 cm, is disclosed.
摘要翻译：一种新的红掌植物，特别是红，耐用的小叶，随着年龄，深绿色，紧致，耐用的叶子，中长直立的花序梗，比叶片更多的花序，丰富的枝条形成，全年自由的花朵慢慢变褐，公开了植物高度约30厘米的紧凑且充分的植物习性。

7. 植物专利

US20080010713P1 ANTHURIUM PLANT NAMED 'ANTHEPEDI' 有权
标题翻译：植物植物名称'ANTHEPEDI'
公开(公告)号：US20080010713P1
公开(公告)日：2008-01-10
申请号：US11482613
申请日：2006-07-07
申请人： Jan Van Dijk
发明人： Jan Van Dijk
IPC分类号： A01H5/00
CPC分类号： A01H5/02
摘要： A new Anthurium plant particularly distinguished by red, durable spathes that slowly turn brown with age, dark-green, compact, durable leaves, medium-long erect penduncle, more inflorescences than leaves, rich shoot formation, flowers early and freely throughout the year, a compact and full plant habit with a plant height around 30 cm, is disclosed.
摘要翻译：一种新的红掌植物特别区分为红色耐用的铲子，随着年龄，深绿色，紧凑，耐用的叶子，中长直立的that藜，比叶片更多的花序，丰富的枝条形成，全年自由的花朵逐渐变褐，公开了植物高度约30厘米的紧凑且充分的植物习性。

8. 发明授权

US4044023A Novel basic substituted-alkylidenamino-oxylalkylcarboxylic-acid esters 失效
标题翻译：新型碱性取代的 - 亚烷基氨基 - 氧基烷基羧酸酯
公开(公告)号：US4044023A
公开(公告)日：1977-08-23
申请号：US509807
申请日：1974-09-27
申请人： Jan Van Dijk , Johannes Maria Antonius Zwagemakers
发明人： Jan Van Dijk , Johannes Maria Antonius Zwagemakers
IPC分类号： C07D209/12 , C07D211/46 , C07D213/30 , C07D215/32 , C07D217/04 , C07D333/22 , C07D333/28 , C07D207/12
CPC分类号： C07D213/30 , C07D209/12 , C07D211/46 , C07D215/32 , C07D217/04 , C07D333/22 , C07D333/28
摘要： The novel compounds of the formula 1 and their acid addition salts have a strong antiinflammatory and a potent analgetic activity and a low toxicity. The substances may be used for treating rheumatic affections. They may be synthetized and formulated into preparations by known methods.
摘要翻译：式1的新化合物及其酸加成盐具有强烈的抗炎和强效的止痛活性和低毒性。这些物质可用于治疗风湿病。它们可以通过已知方法合成并配制成制剂。

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