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1. 发明授权

US09884322B2 Stand for microplates 有权
公开(公告)号：US09884322B2
公开(公告)日：2018-02-06
申请号：US13884738
申请日：2011-11-11
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： B01L9/00
CPC分类号： B01L9/523 , B01L2200/087
摘要： A laboratory stand for a microplate comprises a base (2), at least one post (3, 4) extending upwardly from the base, a shelf (5) located above the base and supported by the at least one post, and means for adjusting the height of the shelf in relation to the base. The shelf (5) comprises a rear portion (9) which is substantially horizontal and a front portion (10), which is inclined downwards away from the horizontal, which is adapted to retain at least one microplate. The laboratory stand improves pipetting ergonomics.

2. 发明授权

US5830359A Method of separating particles from a filter 失效
标题翻译：从过滤器中分离颗粒的方法
公开(公告)号：US5830359A
公开(公告)日：1998-11-03
申请号：US530221
申请日：1995-10-03
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： G01N33/50 , B01D61/00
CPC分类号： G01N33/5094 , G01N33/5002 , Y10T436/255
摘要： Particles that move at low Reynolds numbers are separated from a filter material on which they are adsorbed by subjecting the filter material, in a liquid medium, to agitation of sufficient magnitude to create turbulence and shear forces acting on the filter material such that the particles become desorbed from the filter material and become suspended in the liquid medium. The method may be used to recover biological particles, such as leucocytes and blood platelets, from filter materials on which they are retained by adsorption. The recovered particles may then be used in diagnostic testing and analytical techniques.
摘要翻译： PCT No.PCT / GB94 / 00774 Sec。 371 1995年10月3日第 102（e）日期1995年10月3日PCT 1994年4月7日PCT PCT。第WO94 / 23296号公报日期：1994年10月13日以低雷诺数移动的颗粒物通过使过滤材料在液体介质中受到吸附的过滤材料与其过滤材料分离，以使搅拌足够大，以产生作用在过滤材料上的湍流和剪切力使得颗粒从过滤材料脱附并悬浮在液体介质中。该方法可用于从其通过吸附保留的过滤材料中回收生物颗粒，例如白细胞和血小板。然后将回收的颗粒用于诊断测试和分析技术。

3. 发明申请

US20110237977A1 Device for Collecting First Pass Urine 审中-公开
标题翻译：首次通过尿液收集装置
公开(公告)号：US20110237977A1
公开(公告)日：2011-09-29
申请号：US13127432
申请日：2009-11-18
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： A61B5/20
CPC分类号： A61B10/007
摘要： A device for collecting a sample of the first pass portion of urine voided by a donor isolated from the midstream portion of the urine comprises a first part (1) comprising an opening at its upper end (4) adapted to receive urine voided by a donor, a urine collection body (3) downstream of the upper end and a closable exit (6) located downstream of the urine collection body and at the lower end (5) of the first part, the exit providing a circular orifice (7), a second part (2) located downstream of the exit of the first part and comprising a collecting vessel (10) which is in communication with the exit of the first part, wherein the circular orifice provided by the exit of the first part defines an inlet into the collecting vessel and has a diameter which is smaller than the diameter of the collecting vessel at the upper end thereof, and wherein the collecting vessel contains a moveable closure member (13) for blocking the inlet into the collecting vessel which moveable closure member is capable of floating in urine and is adapted such that, in use, it blocks the inlet into the collecting vessel on the filling of the collecting vessel with urine so as to cause further voided urine to be collected in the urine collection body of the first part. By use of the device, a sample of first pass urine, undiluted by midstream urine, may be collected for medical analysis.
摘要翻译：用于收集由尿液的中游部分隔离的供体排出的尿液的第一通过部分的样品的装置包括第一部分（1），其在其上端（4）处包括适于接收由供体排出的尿的开口，在上端下游的尿液收集体（3）和位于尿液收集体下游的第一部分的下端（5）处的可封闭出口（6），所述出口提供圆形孔口（7），第二部分（2）位于第一部分的出口的下游，并且包括与第一部分的出口连通的收集容器（10），其中由第一部分的出口提供的圆形孔口限定入口进入收集容器并且其直径小于其上端处的收集容器的直径，并且其中收集容器包含用于阻挡进入收集容器的入口的可移动关闭构件（13），可移动闭合构件能够漂浮在尿液中，并且适于使得在使用中，在用尿液填充收集容器时阻止入口进入收集容器，以便使进一步排尿的尿液被收集在第一部分。通过使用该装置，可以采集未经中流尿液稀释的第一通尿样品进行医学分析。

4. 发明授权

US08679761B2 Method for detection of inflammation in the urinary tract or urethra 有权
标题翻译：检测尿道或尿道炎症的方法
公开(公告)号：US08679761B2
公开(公告)日：2014-03-25
申请号：US13634495
申请日：2011-03-15
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： C12Q1/68
CPC分类号： C12Q1/04 , C12Q1/26 , G01N33/56972 , G01N33/571 , G01N33/582 , G01N2333/22 , G01N2333/295
摘要： A method for detecting inflammation in the urinary tract or urethra of a patient, especially urethritis, comprises a) contacting leucocytes obtained from a urine sample provided by the patient with a luminescence reagent which emits light on reaction with an oxidant; b) adding an activator to the mixture of leucocytes and luminescence reagent; c) continuously monitoring and/or measuring light emitted by the luminescence reagent over a predetermined time period commencing before and ending after the addition of the activator. The light emission is indicative of the presence or absence of inflammation in the urinary tract or urethra of the patient. The urine sample is preferably a sample of first pass urine. The method makes possible a diagnosis especially of urethritis and, in particular, urethral infections selected from Chlamydia trachomatis and Neisseria gonorrhoeae, which can be carried out quickly without invasive procedures. A diagnostic kit for carrying out the method, comprising a luminescence reagent which emits light on reaction with an oxidant, an activator and a library of standard signature light emission curves is also disclosed.
摘要翻译：一种用于检测患者尿道或尿道中尤其是尿道炎的炎症的方法，包括：a）将由患者提供的尿液样本获得的白细胞与发射与氧化剂反应的光的发光试剂接触; b）向白细胞和发光试剂的混合物中加入活化剂; c）在从激活剂加入之前和结束之后的预定时间段内连续地监测和/或测量由发光试剂发射的光。发光指示患者尿道或尿道中是否存在炎症。尿液样品优选为第一遍尿样品。该方法可以特别诊断尿道炎，特别是选自沙眼衣原体和淋病奈瑟氏球菌的尿道感染，其可以在没有侵入性手术的情况下快速进行。还公开了一种用于执行该方法的诊断试剂盒，其包括与氧化剂反应发光的发光试剂，活化剂和标准标记光发射曲线库。

5. 发明申请

US20130336853A1 Stand for Microplates 有权
标题翻译：代替微孔板
公开(公告)号：US20130336853A1
公开(公告)日：2013-12-19
申请号：US13884738
申请日：2011-11-11
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： B01L9/00
CPC分类号： B01L9/523 , B01L2200/087
摘要： A laboratory stand for a microplate comprises a base (2), at least one post (3, 4) extending upwardly from the base, a shelf (5) located above the base and supported by the at least one post, and means for adjusting the height of the shelf in relation to the base. The shelf (5) comprises a rear portion (9) which is substantially horizontal and a front portion (10), which is inclined downwards away from the horizontal, which is adapted to retain at least one microplate. The laboratory stand improves pipetting ergonomics.
摘要翻译：用于微孔板的实验室支架包括基部（2），从基部向上延伸的至少一个柱（3,4），位于基部上方并由至少一个支柱支撑的搁架（5），以及用于调节货架相对于底座的高度。搁板（5）包括基本上水平的后部（9）和向前倾斜的前部（10），其适于保持至少一个微板。实验室支架可提高吸液人体工程学。

6. 发明申请

US20130143252A1 Method for Detection of Inflammation in the Urinary Tract or Urethra 有权
标题翻译：检测尿道或尿道炎症的方法
公开(公告)号：US20130143252A1
公开(公告)日：2013-06-06
申请号：US13634495
申请日：2011-03-15
申请人： Jan Knight , Robert Knight
发明人： Jan Knight , Robert Knight
IPC分类号： C12Q1/04 , C12Q1/26
CPC分类号： C12Q1/04 , C12Q1/26 , G01N33/56972 , G01N33/571 , G01N33/582 , G01N2333/22 , G01N2333/295
摘要： A method for detecting inflammation in the urinary tract or urethra of a patient, especially urethritis, comprises a) contacting leucocytes obtained from a urine sample provided by the patient with a luminescence reagent which emits light on reaction with an oxidant; b) adding an activator to the mixture of leucocytes and luminescence reagent; c) continuously monitoring and/or measuring light emitted by the luminescence reagent over a predetermined time period commencing before and ending after the addition of the activator. The light emission is indicative of the presence or absence of inflammation in the urinary tract or urethra of the patient. The urine sample is preferably a sample of first pass urine. The method makes possible a diagnosis especially of urethritis and, in particular, urethral infections selected from Chlamydia trachomatis and Neisseria gonorrhoeae, which can be carried out quickly without invasive procedures. A diagnostic kit for carrying out the method, comprising a luminescence reagent which emits light on reaction with an oxidant, an activator and a library of standard signature light emission curves is also disclosed.
摘要翻译：一种用于检测患者尿道或尿道中尤其是尿道炎的炎症的方法，包括：a）将由患者提供的尿样获得的白细胞与发出与氧化剂反应的光的发光试剂接触; b）向白细胞和发光试剂的混合物中加入活化剂; c）在从激活剂加入之前和结束之后的预定时间段内连续地监测和/或测量由发光试剂发射的光。发光指示患者尿道或尿道中是否存在炎症。尿液样品优选为第一遍尿样品。该方法可以特别诊断尿道炎，特别是选自沙眼衣原体和淋病奈瑟氏球菌的尿道感染，其可以在没有侵入性手术的情况下快速进行。还公开了一种用于执行该方法的诊断试剂盒，其包括与氧化剂反应发光的发光试剂，活化剂和标准标记光发射曲线库。

7. 发明授权

US08949637B2 Obtaining power profile information with low overhead 有权
标题翻译：以低开销获取电源配置文件信息
公开(公告)号：US08949637B2
公开(公告)日：2015-02-03
申请号：US13070700
申请日：2011-03-24
申请人： Robert Knight
发明人： Robert Knight
IPC分类号： G06F1/00 , G06F1/32
CPC分类号： G06F1/3206 , G06F1/3287 , G06F11/3024 , G06F11/3058 , G06F11/3093 , G06F2201/86 , G06F2201/88 , Y02D10/171 , Y02D50/20
摘要： In one embodiment, a method includes, upon occurrence of multiple power state transition events for a core of a multi-core processor, reading a value of a system counter of the core and values of low power counters of the core, without expiration of a timer or triggering of an interrupt. These values can be stored in a storage of the processor. Then, after collection is completed, the storage can be accessed to determine a power profile of the processor using the stored values. Other embodiments are described and claimed.
摘要翻译：在一个实施例中，一种方法包括在多核处理器的核心发生多个功率状态转换事件时，读取核心的系统计数器的值和该核心的低功率计数器的值，而不会使定时器或触发中断。这些值可以存储在处理器的存储器中。然后，在收集完成之后，可以访问存储器以使用存储的值来确定处理器的功率分布。描述和要求保护其他实施例。

8. 发明授权

US08762694B1 Programmable event-driven yield mechanism 有权
标题翻译：可编程事件驱动产出机制
公开(公告)号：US08762694B1
公开(公告)日：2014-06-24
申请号：US11395884
申请日：2006-03-31
申请人： Xiang Zou , Hong Wang , Robert Knight , Robert Geva , Gautham Chinya , Scott Dion Rodgers , Chris Newburn , Bryant E. Bigbee , Per Hammarlund , Ittai Anati , Jim B. Crossland , John P. Shen
发明人： Xiang Zou , Hong Wang , Robert Knight , Robert Geva , Gautham Chinya , Scott Dion Rodgers , Chris Newburn , Bryant E. Bigbee , Per Hammarlund , Ittai Anati , Jim B. Crossland , John P. Shen
IPC分类号： G06F9/48
CPC分类号： G06F9/3851 , G06F9/3009 , G06F9/4843 , G06F11/3409 , G06F11/348 , G06F2201/86 , G06F2201/88 , G06F2201/885
摘要： Method, apparatus, and system for a programmable event-driven yield mechanism. The mechanism may disrupt processing of a program to deliver a yield event. The event may be treated as a fault-like yield event or a trap-like event. For a fault-like yield event, the faulting instruction is canceled before retirement and processor state is not updated before the yield event is delivered. For a trap-like yield event the instruction causing the trap is retired and the yield event is delivered on an interrupt boundary. Multiple pending yield events may be handled according to priority. Other embodiments are also described and claimed.
摘要翻译：用于可编程事件驱动产出机制的方法，装置和系统。该机制可能会中断处理程序以传递yield事件。事件可能被视为类似故障的收益事件或类似陷阱的事件。对于类似故障的产出事件，在退出之前取消故障指令，并且在发送收益事件之前未更新处理器状态。对于类似陷阱的收益事件，导致陷阱的指令将被退出，并且收益事件在中断边界上传递。可以根据优先级处理多个待处理的收益事件。还描述和要求保护其他实施例。

9. 发明授权

US08171270B2 Asynchronous control transfer 有权
标题翻译：异步控制传输
公开(公告)号：US08171270B2
公开(公告)日：2012-05-01
申请号：US11648187
申请日：2006-12-29
申请人： Chris J. Newburn , Dion Rodgers , Robert Knight , Ittai Anati , Aaron N. Levinson , Gautham Chinya
发明人： Chris J. Newburn , Dion Rodgers , Robert Knight , Ittai Anati , Aaron N. Levinson , Gautham Chinya
IPC分类号： G06F9/00
CPC分类号： G06F9/542
摘要： Methods and apparatus to perform asynchronous control transfer are described. In one embodiment, upon occurrence of an event (e.g., an architectural event), a service routine data block (SRDB) is accessed via a service routine base pointer (SRDS) and a service routine offset value (SRDBP) to obtain the address of a yield service routine via a service routine instruction pointer (SRIP) and a service routine code segment (SRCS). Other embodiments are also described.
摘要翻译：描述了执行异步控制传输的方法和装置。在一个实施例中，在发生事件（例如，架构事件）时，经由服务例程基本指针（SRDS）和服务例程偏移值（SRDBP）访问服务例程数据块（SRDB），以获得通过服务例程指令指针（SRIP）和服务程序代码段（SRCS）的收益服务程序。还描述了其它实施例。

10. 发明申请

US20130031557A1 System To Profile And Optimize User Software In A Managed Run-Time Environment 有权
标题翻译：在管理运行时环境中配置和优化用户软件的系统
公开(公告)号：US20130031557A1
公开(公告)日：2013-01-31
申请号：US13529630
申请日：2012-06-21
申请人： Chris J. Newburn , Robert Knight , Robert Geva , Dion Rodgers , Xiang Zou , Hong Wang , Bryant E. Bigbee , Ittai Anati
发明人： Chris J. Newburn , Robert Knight , Robert Geva , Dion Rodgers , Xiang Zou , Hong Wang , Bryant E. Bigbee , Ittai Anati
IPC分类号： G06F9/46
CPC分类号： G06F9/542 , G06F11/348 , G06F11/3612 , G06F2201/86 , G06F2201/885
摘要： Method, apparatus, and system for monitoring performance within a processing resource, which may be used to modify user-level software. Some embodiments of the invention pertain to an architecture to allow a user to improve software running on a processing resources on a per-thread basis in real-time and without incurring significant processing overhead.
摘要翻译：用于监控处理资源内的性能的方法，装置和系统，其可用于修改用户级软件。本发明的一些实施例涉及允许用户实时地在每个线程的基础上改进在处理资源上运行的软件并且不产生显着的处理开销的架构。

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