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1. 发明授权

US09125969B2 Methods of making and using surfactant polymers 有权
标题翻译：制造和使用表面活性剂聚合物的方法
公开(公告)号：US09125969B2
公开(公告)日：2015-09-08
申请号：US13422150
申请日：2012-03-16
申请人： Jan J. Lewandowski , Yubiao Liu , Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
发明人： Jan J. Lewandowski , Yubiao Liu , Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
IPC分类号： A61L27/34 , A61L29/08 , A61L31/10 , A61L33/00 , A61L33/08 , A61L33/12 , C08B37/02 , C08B37/00 , C08F8/00
CPC分类号： A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C08B37/0021 , C08B37/0078 , C08F8/00 , C08L101/00 , C08F26/02 , C08F16/06
摘要： Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
摘要翻译：提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。这种表面活性剂聚合物包含具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团与主链连接的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链。还提供了涂有表面活性剂聚合物的医疗装置。表面活性剂聚合物可用于降低医疗装置的血栓形成性质，包封和细菌定植。

2. 发明授权

US08163302B2 Methods of making and using surfactant polymers 有权
标题翻译：制造和使用表面活性剂聚合物的方法
公开(公告)号：US08163302B2
公开(公告)日：2012-04-24
申请号：US12062768
申请日：2008-04-04
申请人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
发明人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
IPC分类号： A61F2/08
CPC分类号： A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C08B37/0021 , C08B37/0078 , C08F8/00 , C08L101/00 , C08F26/02 , C08F16/06
摘要： Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
摘要翻译：提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。这种表面活性剂聚合物包含具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团与主链连接的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链。还提供了涂有表面活性剂聚合物的医疗装置。表面活性剂聚合物可用于降低医疗装置的血栓形成性质，包封和细菌定植。

3. 发明授权

US06759388B1 Surfactants that mimic the glycocalyx 有权
标题翻译：模仿糖萼的表面活性剂
公开(公告)号：US06759388B1
公开(公告)日：2004-07-06
申请号：US09302195
申请日：1999-04-29
申请人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
发明人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
IPC分类号： B32B2700
CPC分类号： C07K7/06 , A61L27/34 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C07K5/0817 , C07K5/1019 , C08B37/0021 , C08F8/00 , C08F26/02 , C08F16/06
摘要： Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to said backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. The hydrophobic side chains comprise an alkyl group comprising from 2 to 18 methylene groups. The alkyl groups are linked to the polymeric backbone through ester linkages, secondary amine linkages, or, preferably, amide linkages. The hydrophilic side chain is selected from the group consisting of: a neutral oligosaccharide, which, preferably, has weight average molecular weight of less than 7000; a charged oligosaccharide, preferably a negatively charged oligosaccharide having a weight average molecular weight of less than 10,000; an oligopeptide of from about 3 to about 30 amino acid residues, said oligopeptide having an amino acid sequence which interacts with protein receptors on the surface of cells; and combinations thereof. Methods of making the surfactant polymers and using the surfactant polymers to alter the surface properties of a biomaterial are also provided.
摘要翻译：提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。这种表面活性剂聚合物包括具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团连接到所述主链的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链。疏水侧链包括含有2至18个亚甲基的烷基。烷基通过酯键，仲胺键或优选酰胺键与聚合物主链相连。亲水侧链选自：中性寡糖，其优选具有小于7000的重均分子量; 带电荷的寡糖，优选具有小于10,000的重均分子量的带负电荷的寡糖; 所述寡肽具有约3至约30个氨基酸残基的寡肽，所述寡肽具有与细胞表面上的蛋白受体相互作用的氨基酸序列; 及其组合。还提供了使表面活性剂聚合物和使用表面活性剂聚合物改变生物材料的表面性质的方法。

4. 发明授权

US07276474B2 Methods of making and using surfactant polymers 有权
标题翻译：制造和使用表面活性剂聚合物的方法
公开(公告)号：US07276474B2
公开(公告)日：2007-10-02
申请号：US10823218
申请日：2004-04-13
申请人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
发明人： Roger E. Marchant , Tianhong Zhang , Yongxing Qiu , Mark A. Ruegsegger
IPC分类号： A61K38/16
CPC分类号： C07K7/06 , A61L27/34 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C07K5/0817 , C07K5/1019 , C08B37/0021 , C08F8/00 , C08F26/02 , C08F16/06
摘要： Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to said backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. The hydrophobic side chains comprise an alkyl group comprising from 2 to 18 methylene groups. The alkyl groups are linked to the polymeric backbone through ester linkages, secondary amine linkages, or, preferably, amide linkages. The hydrophilic side chain is selected from the group consisting of: a neutral oligosaccharide, which, preferably, has weight average molecular weight of less than 7000; a charged oligosaccharide, preferably a negatively charged oligosaccharide having a weight average molecular weight of less than 10,000; an oligopeptide of from about 3 to about 30 amino acid residues, said oligopeptide having an amino acid sequence which interacts with protein receptors on the surface of cells; and combinations thereof. Methods of making the surfactant polymers and using the surfactant polymers to alter the surface properties of a biomaterial are also provided.
摘要翻译：提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。这种表面活性剂聚合物包括具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团连接到所述主链的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链。疏水侧链包括含有2至18个亚甲基的烷基。烷基通过酯键，仲胺键或优选酰胺键与聚合物主链相连。亲水侧链选自：中性寡糖，其优选具有小于7000的重均分子量; 带电荷的寡糖，优选具有小于10,000的重均分子量的带负电荷的寡糖; 所述寡肽具有约3至约30个氨基酸残基的寡肽，所述寡肽具有与细胞表面上的蛋白受体相互作用的氨基酸序列; 及其组合。还提供了使表面活性剂聚合物和使用表面活性剂聚合物改变生物材料的表面性质的方法。

5. 发明申请

US20050008603A1 Methods of making and using surfactant polymers 有权
标题翻译：制造和使用表面活性剂聚合物的方法
公开(公告)号：US20050008603A1
公开(公告)日：2005-01-13
申请号：US10823218
申请日：2004-04-13
申请人： Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark Ruegsegger
发明人： Roger Marchant , Tianhong Zhang , Yongxing Qiu , Mark Ruegsegger
IPC分类号： A61L27/34 , A61L31/10 , A61L33/00 , A61L33/08 , A61L33/12 , C07K5/09 , C07K5/10 , C07K7/06 , C08B37/02 , C08F8/00 , A61K7/06 , A61K7/11 , C08G63/48 , C08G63/91
CPC分类号： C07K7/06 , A61L27/34 , A61L31/10 , A61L33/0017 , A61L33/08 , A61L33/128 , C07K5/0817 , C07K5/1019 , C08B37/0021 , C08F8/00 , C08F26/02 , C08F16/06
摘要： Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to said backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. The hydrophobic side chains comprise an alkyl group comprising from 2 to 18 methylene groups. The alkyl groups are linked to the polymeric backbone through ester linkages, secondary amine linkages, or, preferably, amide linkages. The hydrophilic side chain is selected from the group consisting of: a neutral oligosaccharide, which, preferably, has weight average molecular weight of less than 7000; a charged oligosaccharide, preferably a negatively charged oligosaccharide having a weight average molecular weight of less than 10,000; an oligopeptide of from about 3 to about 30 amino acid residues, said oligopeptide having an amino acid sequence which interacts with protein receptors on the surface of cells; and combinations thereof. Methods of making the surfactant polymers and using the surfactant polymers to alter the surface properties of a biomaterial are also provided.
摘要翻译：提供了梳状，用于改变生物材料表面性质的表面活性剂聚合物。这种表面活性剂聚合物包括具有用于与侧链偶联的官能团的重复单体单元的聚合物主链，经由官能团连接到所述主链的多个疏水侧链，以及通过官能团连接至所述骨架的多个亲水侧链。疏水侧链包括含有2至18个亚甲基的烷基。烷基通过酯键，仲胺键或优选酰胺键与聚合物主链相连。亲水侧链选自：中性寡糖，其优选具有小于7000的重均分子量; 带电荷的寡糖，优选具有小于10,000的重均分子量的带负电荷的寡糖; 所述寡肽具有约3至约30个氨基酸残基的寡肽，所述寡肽具有与细胞表面上的蛋白受体相互作用的氨基酸序列; 及其组合。还提供了使表面活性剂聚合物和使用表面活性剂聚合物改变生物材料的表面性质的方法。

6. 发明申请

US20080142982A1 Semiconductor constructions, semiconductor processing methods, methods of forming contact pads, and methods of forming electrical connections between metal-containing layers 有权
标题翻译：半导体结构，半导体加工方法，形成接触焊盘的方法，以及在含金属层之间形成电连接的方法
公开(公告)号：US20080142982A1
公开(公告)日：2008-06-19
申请号：US11639771
申请日：2006-12-15
申请人： Tianhong Zhang , Akram Ditali
发明人： Tianhong Zhang , Akram Ditali
IPC分类号： H01L23/52 , H01L21/4763
CPC分类号： H01L23/49866 , H01L23/53238 , H01L24/03 , H01L24/05 , H01L2224/05647 , H01L2924/01006 , H01L2924/01013 , H01L2924/01014 , H01L2924/01022 , H01L2924/01028 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01074 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/05042 , H01L2924/14 , H01L2924/00014
摘要： Some embodiments include semiconductor processing methods in which a copper barrier is formed to be laterally offset from a copper component, and in which nickel is formed to extend across both the barrier and the component. The barrier may extend around an entire lateral periphery of the component, and may be spaced from the component by an intervening ring of electrically insulative material. The copper component may be a bond pad or an interconnect between two levels of metal layers. Some embodiments include semiconductor constructions in which nickel extends across a copper component, a copper barrier is laterally offset from the copper component, and an insulative material is between the copper barrier and the copper component.
摘要翻译：一些实施例包括半导体处理方法，其中铜屏障形成为从铜部件横向偏移，并且其中形成镍以跨越屏障和部件延伸。屏障可以围绕部件的整个横向周边延伸，并且可以通过电绝缘材料的中间环与部件间隔开。铜组分可以是接合焊盘或两层金属层之间的互连。一些实施方案包括其中镍延伸穿过铜组分的半导体结构，铜屏障横向偏离铜组分，并且绝缘材料位于铜屏障和铜组分之间。

7. 发明授权

US07078249B2 Process for forming sharp silicon structures 失效
标题翻译：形成尖锐硅结构的工艺
公开(公告)号：US07078249B2
公开(公告)日：2006-07-18
申请号：US11074187
申请日：2005-03-07
申请人： Tianhong Zhang
发明人： Tianhong Zhang
IPC分类号： H01L21/00
CPC分类号： H01J9/025 , H01J31/127 , H01J2209/0226
摘要： A method of forming a sharp silicon structure, such as a silicon field emitter, includes oxidizing the silicon structure to form an oxide layer thereon, then removing the oxide layer. Oxidizing may occur at a low temperature and form a relatively thin (e.g., about 20 Å to about 40 Å) oxide layer on the silicon field emitter. The oxide layer may be removed by etching. A silicon field emitter that has been fabricated in accordance with the method is substantially free of crystalline defects and may include an emitter tip having a diameter as small as about 40 Å to about 20 Å or less.
摘要翻译：形成诸如硅场发射体的尖锐硅结构的方法包括氧化硅结构以在其上形成氧化层，然后除去氧化物层。氧化可以在低温下发生，并在硅场发射体上形成较薄（例如，大约至大约）的氧化物层。可以通过蚀刻去除氧化物层。已经根据该方法制造的硅场发射器基本上没有晶体缺陷，并且可以包括直径为大约至大约等于或者小于等于20埃的发射极尖端。

8. 发明授权

US06726518B2 Electrode structures, display devices containing the same, and methods for making the same 失效
标题翻译：电极结构，含有其的显示装置及其制造方法
公开(公告)号：US06726518B2
公开(公告)日：2004-04-27
申请号：US10198897
申请日：2002-07-19
申请人： Benham Moradi , Zhong-Yi Xia , Tianhong Zhang
发明人： Benham Moradi , Zhong-Yi Xia , Tianhong Zhang
IPC分类号： H01J902
CPC分类号： H01J3/022 , H01J2329/00
摘要： A method for making an electrode structure and an electrode structure for a display device comprising a gate electrode proximate to an emitter and a focusing electrode separated from the gate electrode by an insulating layer containing a ridge. When the focusing electrode is an aperture-type electrode, the upper surface of the ridge protrudes closer to the emitter than the sidewall of the gate electrode or the sidewall of the focusing electrode. When the focusing electrode is a concentric-type electrode, the ridge protrudes above the upper surface of the gate electrode or the upper surface of the focusing electrode.
摘要翻译：一种用于制造用于显示装置的电极结构和电极结构的方法，包括靠近发射极的栅电极和通过包含脊的绝缘层与栅电极分离的聚焦电极。当聚焦电极是孔型电极时，脊的上表面比栅电极的侧壁或聚焦电极的侧壁更靠近发射极。当聚焦电极是同心型电极时，脊突出在栅电极的上表面或聚焦电极的上表面之上。

9. 发明授权

US06348403B1 Suppression of hillock formation in thin aluminum films 失效
标题翻译：在薄铝膜中抑制小丘形成
公开(公告)号：US06348403B1
公开(公告)日：2002-02-19
申请号：US09652423
申请日：2000-08-31
申请人： Kanwal K. Raina , Tianhong Zhang , Allen McTeer
发明人： Kanwal K. Raina , Tianhong Zhang , Allen McTeer
IPC分类号： H01L214763
CPC分类号： H01L21/7685 , H01J1/3044 , H01J9/025 , H01L21/32051 , H01L21/76864 , H01L23/53223 , H01L2924/0002 , H01L2924/00
摘要： A multilayer structure is provided which suppresses hillock formation due to post-heat treatment steps in thin aluminum films deposited on other substrates by sandwiching the aluminum film between thin layers of aluminum titanium nitride. The first aluminum titanium nitride layer acts as a compatibilizing layer to provide a better match between the coefficients of thermal expansion of the substrate and aluminum metal layer. The second aluminum titanium nitride layer acts as a cap layer to suppress hillock formation.
摘要翻译：提供了一种多层结构，其通过将铝膜夹在铝氮化钛薄层之间，通过在其它基板上沉积的薄铝膜中的后热处理步骤来抑制小丘形成。第一铝氮化钛层用作增容层，以提供基板和铝金属层的热膨胀系数之间更好的匹配。第二铝氮化钛层用作盖层以抑制小丘形成。

10. 发明授权

US6165808A Low temperature process for sharpening tapered silicon structures 失效
标题翻译：用于磨削锥形硅结构的低温工艺
公开(公告)号：US6165808A
公开(公告)日：2000-12-26
申请号：US166864
申请日：1998-10-06
申请人： Tianhong Zhang
发明人： Tianhong Zhang
IPC分类号： H01J9/02 , H01L21/00
CPC分类号： H01J9/025 , H01J31/127 , H01J2209/0226
摘要： A method of sharpening a tapered or pointed silicon structure, such as a silicon field emitter. The method includes oxidizing the silicon field emitter to form an oxide layer thereon and removing the oxide layer. Oxidizing occurs at a low temperature and forms a relatively thin (e.g., about 20 .ANG. to about 40 .ANG.) oxide layer on the silicon field emitter. The oxide layer may be removed by etching. The method may be employed to sharpen existing silicon structures or in fabricating tapered or pointed silicon structures. A silicon field emitter that has been sharpened or fabricated in accordance with the method is substantially free of crystalline defects and includes an emitter tip having a diameter as small as about 40 .ANG. to about 20 .ANG. or less.
摘要翻译：锐化锥形或尖锐硅结构的方法，例如硅场发射器。该方法包括氧化硅场发射体以在其上形成氧化物层并去除氧化物层。在低温下发生氧化，并在硅场发射体上形成较薄的（例如，约20安格姆至约40纳米）的氧化物层。可以通过蚀刻去除氧化物层。该方法可用于锐化现有的硅结构或制造锥形或尖晶硅结构。已经根据该方法被削尖或制造的硅场发射器基本上没有晶体缺陷，并且包括直径小至约40至约20Am或更小的发射极尖端。

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