专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08540968B2 Phospholipid ether analogs as agents for detecting and locating cancer, and methods thereof 有权
标题翻译：磷脂醚类似物作为检测和定位癌症的药剂及其方法
公开(公告)号：US08540968B2
公开(公告)日：2013-09-24
申请号：US11316620
申请日：2005-12-20
申请人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
发明人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
IPC分类号： A61K49/00
CPC分类号： A61K51/0408 , A61K49/0017 , A61K51/04 , C07F13/005 , G01N33/57492
摘要： The present invention provides methods for treating, detecting and locating recurrence of cancer, radiation and chemo insensitive cancer or metastasis of cancer selected from the group consisting of Lung cancer, Adrenal cancer, Melanoma, Colon cancer, Colorectal cancer, Ovarian cancer, Prostate cancer, Liver cancer, Subcutaneous cancer, Squamous cell cancer, Intestinal cancer, Hepatocellular carcinoma, Retinoblastoma, Cervical cancer, Glioma, Breast cancer and Pancreatic cancer in subject using phospholipid ether analogs.
摘要翻译：本发明提供了治疗，检测和定位癌症，辐射和化学不敏感性癌症或癌症转移的复发的方法，其选自肺癌，肾上腺癌，黑色素瘤，结肠癌，结肠直肠癌，卵巢癌，前列腺癌，肝癌，皮下癌，鳞状细胞癌，肠癌，肝细胞癌，视网膜母细胞瘤，宫颈癌，胶质瘤，乳腺癌和胰腺癌患者使用磷脂醚类似物。

2. 发明授权

US08535641B2 Phospholipid analogs as diapeutic* agents and methods thereof 有权
标题翻译：磷脂类似物作为治疗剂及其方法
公开(公告)号：US08535641B2
公开(公告)日：2013-09-17
申请号：US10906687
申请日：2005-03-02
申请人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
发明人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： A61K51/0489 , A61K49/0017 , A61K51/04 , A61K51/0408 , C07F13/005 , C12Q1/34 , G01N33/57492
摘要： The present invention provides methods and uses of phospholipid ether analogs as diagnostic and therapeutic agents for numerous cancers.
摘要翻译：本发明提供磷脂醚类似物作为许多癌症的诊断和治疗剂的方法和用途。

3. 发明申请

US20070020178A1 Phospholipid ether analogs as cancer treatment agents and methods thereof 有权
标题翻译：磷脂醚类似物作为癌症治疗剂及其方法
公开(公告)号：US20070020178A1
公开(公告)日：2007-01-25
申请号：US11316620
申请日：2005-12-20
申请人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
发明人： Jamey Weichert , Marc Longino , Anatoly Pinchuk
IPC分类号： A61K51/00
CPC分类号： A61K51/0408 , A61K49/0017 , A61K51/04 , C07F13/005 , G01N33/57492
摘要： The present invention provides methods for treating, detecting and locating recurrence of cancer, radiation and chemo insensitive cancer or metastasis of cancer selected from the group consisting of Lung cancer, Adrenal cancer, Melanoma, Colon cancer, Colorectal cancer, Ovarian cancer, Prostate cancer, Liver cancer, Subcutaneous cancer, Squamous cell cancer, Intestinal cancer, Hepatocellular carcinoma, Retinoblastoma, Cervical cancer, Glioma, Breast cancer and Pancreatic cancer in subject using phospholipid ether analogs.
摘要翻译：本发明提供了治疗，检测和定位癌症，辐射和化学不敏感性癌症或癌症转移的复发的方法，其选自肺癌，肾上腺癌，黑色素瘤，结肠癌，结肠直肠癌，卵巢癌，前列腺癌，肝癌，皮下癌，鳞状细胞癌，肠癌，肝细胞癌，视网膜母细胞瘤，宫颈癌，胶质瘤，乳腺癌和胰腺癌患者使用磷脂醚类似物。

4. 发明申请

US20080075660A1 Near infrared-fluorescence using phospholipid ether analog dyes in endoscopic applications 审中-公开
标题翻译：在内窥镜应用中使用磷脂醚类似物染料近红外荧光
公开(公告)号：US20080075660A1
公开(公告)日：2008-03-27
申请号：US11891939
申请日：2007-08-14
申请人： Jamey Weichert , Marc Longino , Anatoly Pinchuk , Andreas Muehler
发明人： Jamey Weichert , Marc Longino , Anatoly Pinchuk , Andreas Muehler
IPC分类号： A61K51/04 , A61B8/12 , A61P43/00
CPC分类号： A61B5/411 , A61B5/0071 , A61B5/0086 , A61B5/415 , A61B5/417 , A61B5/418 , A61K49/0021 , A61K49/0032 , A61K49/0039 , A61K49/0052 , A61K51/0408
摘要： The present invention provides composition and methods of use of phospholipid dyes for use in detection of neoplastic tissue, typically using the routing procedure of endoscopy and methods of optimizing therapy treatment in a subject.
摘要翻译：本发明提供了用于检测肿瘤组织的磷脂染料的组合物和方法，通常使用内窥镜检查的路线选择方法和优化受试者治疗的方法。

5. 发明申请

US20060228298A1 IMAGING AND SELECTIVE RETENTION OF PHOSPHOLIPID ETHER ANALOGS 有权
标题翻译：磷光体类似物的成像和选择性保留
公开(公告)号：US20060228298A1
公开(公告)日：2006-10-12
申请号：US11382645
申请日：2006-05-10
申请人： Jamey Weichert , Marc Longino , Sharon Weber , Joseph Nwankwo
发明人： Jamey Weichert , Marc Longino , Sharon Weber , Joseph Nwankwo
IPC分类号： A61K51/00 , A61K49/10 , A61K49/00 , C12Q1/68 , C12Q1/42
CPC分类号： C12Q1/42 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16
摘要： The present invention generally relates to imaging and selective retention of phospholipid ether analogs in various neoplastic tissues. Specifically, the present invention relates to imaging and methods for selective retention of analogs, for example, NM404, in cancers such as Colorectal Cancer.
摘要翻译：本发明一般涉及磷脂醚类似物在各种肿瘤组织中的成像和选择性保留。具体而言，本发明涉及用于在诸如结肠直肠癌的癌症中选择性保留类似物（例如NM404）的成像和方法。

6. 发明申请

US20060013767A1 Virtual colonoscopy with radiolabeled phospholipid ether analogs 有权
标题翻译：具有放射性标记的磷脂醚类似物的虚拟结肠镜检查
公开(公告)号：US20060013767A1
公开(公告)日：2006-01-19
申请号：US11177749
申请日：2005-07-08
申请人： Jamey Weichert , Marc Longino
发明人： Jamey Weichert , Marc Longino
IPC分类号： A61K51/00
CPC分类号： A61K51/0408 , A61B6/037 , A61B6/508
摘要： The present invention provides agents and methods for dual modality virtual colonoscopy that gives both anatomical and functional information using hybrid CT/PET scanning. In preferred embodiments, the present invention provides radiolabeled tumor-specific agents and methods for distinguishing benign polyps from malignant tumors. In further embodiments, the present invention provides compositions and methods useful for distinguishing morphological and functional subregions of a selected region of tissue based on relative levels of phospholipid metabolism. Preferred radiolabeled tumor-specific agents are phospholipid ether analogs labeled with a halogen radiosiotope. In certain preferred embodiments, the compositions including radiolabeled phospholipid ether analogs have therapeutic actions in addition to functionally identifying malignant tissue.
摘要翻译：本发明提供用于双重模态虚拟结肠镜检查的药剂和方法，其使用混合CT / PET扫描给出解剖和功能信息。在优选的实施方案中，本发明提供放射性标记的肿瘤特异性试剂和用于区分良性息肉与恶性肿瘤的方法。在另外的实施方案中，本发明提供了基于相对磷脂代谢水平来区分组织选定区域的形态学和功能亚区域的组合物和方法。优选的放射性标记的肿瘤特异性试剂是用卤素无机物质标记的磷脂醚类似物。在某些优选实施方案中，包括放射性标记的磷脂醚类似物的组合物除了在功能上鉴定恶性组织之外还具有治疗作用。

7. 发明申请

US20070098633A2 VIRTUAL COLONOSCOPY WITH RADIOLABELED PHOSPHOLIPID ETHER ANALOGS 有权
标题翻译：具有放射性磷脂醚类似物的虚拟结构
公开(公告)号：US20070098633A2
公开(公告)日：2007-05-03
申请号：US11177749
申请日：2005-07-08
申请人： Jamey Weichert , Marc Longino
发明人： Jamey Weichert , Marc Longino
IPC分类号： A61K51/00
CPC分类号： A61K51/0408 , A61B6/037 , A61B6/508
摘要： The present invention provides agents and methods for dual modality virtual colonoscopy that gives both anatomical and functional information using hybrid CT/PET scanning. In preferred embodiments, the present invention provides radiolabeled tumor-specific agents and methods for distinguishing benign polyps from malignant tumors. In further embodiments, the present invention provides compositions and methods useful for distinguishing morphological and functional subregions of a selected region of tissue based on relative levels of phospholipid metabolism. Preferred radiolabeled tumor-specific agents are phospholipid ether analogs labeled with a halogen radioisotope. In certain preferred embodiments, the compositions including radiolabeled phospholipid ether analogs have therapeutic actions in addition to functionally identifying malignant tissue.
摘要翻译：本发明提供用于双重模态虚拟结肠镜检查的药剂和方法，其使用混合CT / PET扫描给出解剖和功能信息。在优选的实施方案中，本发明提供放射性标记的肿瘤特异性试剂和用于区分良性息肉与恶性肿瘤的方法。在另外的实施方案中，本发明提供了基于相对磷脂代谢水平来区分组织选定区域的形态学和功能亚区域的组合物和方法。优选的放射性标记的肿瘤特异性试剂是用卤素放射性同位素标记的磷脂醚类似物。在某些优选实施方案中，包括放射性标记的磷脂醚类似物的组合物除了在功能上鉴定恶性组织之外还具有治疗作用。

8. 发明申请

US20060115426A1 Methods of detecting breast cancer, brain cancer, and pancreatic cancer 审中-公开
标题翻译：检测乳腺癌，脑癌和胰腺癌的方法
公开(公告)号：US20060115426A1
公开(公告)日：2006-06-01
申请号：US11201793
申请日：2005-08-11
申请人： Jamey Weichert , Marc Longino , Amy Moser
发明人： Jamey Weichert , Marc Longino , Amy Moser
IPC分类号： A61K51/00 , C07F9/02
CPC分类号： A61K51/0408
摘要： The present invention discloses methods for detecting breast cancer, brain cancer, and pancreatic cancer via nuclear imaging using certain phospholipid ether analogs.
摘要翻译：本发明公开了使用某些磷脂醚类似物通过核成像检测乳腺癌，脑癌和胰腺癌的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式