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    • 8. 发明授权
    • Contrast agents to improve gastrointestinal tract opacification during abdominal and pelvic CT scans
    • 腹部和盆腔CT扫描改善胃肠道不透明的对比剂
    • US07582283B2
    • 2009-09-01
    • US10794043
    • 2004-03-05
    • Andrew J. TaylorJeffrey J. HebertThomas C. Winter, III
    • Andrew J. TaylorJeffrey J. HebertThomas C. Winter, III
    • A61K49/04A61B5/05
    • A61K49/0452
    • Methods of imaging a portion of a body of a patient are provided. In the methods, a contrast agent including an iso-osmotic contrast agent is administered to the patient. In a preferred embodiment, the iso-osmotic contrast agent comprises polyethylene glycol (PEG) and electrolytes, which make the PEG iso-osmotic. In a preferred embodiment, a positive contrast agent, such as an iodine-based contrast agent, is added to the PEG. The iso-osmotic contrast agent can be administered in volumes that are lower than previous contrast agents. The iso-osmotic contrast agent can be administered in combination with a positive intravenous contrast agent. At least one image of the portion of the patient's body is obtained, such as by computed tomography, after the contrast agent is administered. The methods can be used to image a pelvis, GI tract, and/or appendix of the patient. Iso-osmotic contrast agents are also provided.
    • 提供了对患者的身体的一部分进行成像的方法。 在该方法中,向患者施用包含异渗透造影剂的造影剂。 在优选的实施方案中,等渗造影剂包括聚乙二醇(PEG)和电解质,其使PEG等渗。 在优选的实施方案中,向PEG中加入阳性造影剂,例如碘基造影剂。 等渗造影剂可以以比先前造影剂低的体积施用。 等渗造影剂可以与阳性静脉造影剂组合施用。 在施用造影剂之后,例如通过计算机断层摄影获得患者身体部分的至少一个图像。 该方法可用于对患者的骨盆,胃肠道和/或阑尾进行成像。 还提供了同渗渗造影剂。