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1. 发明申请

US20060055550A1 Wheelchair and alarm therefor 审中-公开
公开(公告)号：US20060055550A1
公开(公告)日：2006-03-16
申请号：US11253131
申请日：2005-10-18
申请人： James Marquis , James Ritchie
发明人： James Marquis , James Ritchie
IPC分类号： G08B21/00
CPC分类号： A61B5/1115 , A61B5/6894 , A61G5/0825 , A61G5/10 , A61G5/1054 , A61G2203/34
摘要： The present invention relates to a wheelchair and an underseat alarm system therefor.

2. 发明申请

US20080298970A1 Turbo Machine 审中-公开
标题翻译：涡轮机
公开(公告)号：US20080298970A1
公开(公告)日：2008-12-04
申请号：US12045895
申请日：2008-03-11
申请人： Joergen Ferber , James Ritchie , Slawomir Slowik
发明人： Joergen Ferber , James Ritchie , Slawomir Slowik
IPC分类号： F01D5/22
CPC分类号： F01D5/225 , F05B2240/33 , F05D2230/60 , F05D2260/30 , Y02T50/671 , Y02T50/673
摘要： A turbo machine (1, 101), in particular turbine or compressor, includes a rotor (2, 102) which has at least one moving blade row (4, 104) with a plurality of moving blades (5, 105), and a stator (3) which has at least one guide vane row (6, 106) with a plurality of guide vanes (7, 107), at least one moving blade row (4, 104) having a shroud (8, 108). The shroud (8, 108) is designed to be self-supporting in such a way that it can at least partially absorb the centrifugal forces arising during operation and discharge them in the circumferential direction.
摘要翻译：特别是涡轮机或压缩机的涡轮机（1,101）包括具有至少一个具有多个活动叶片（5,105）的活动叶片排（4,104）的转子（2,102），以及定子（3）具有至少一个具有多个导向叶片（7,107）的导向叶片排（6,106），至少一个具有护罩（8,108）的活动叶片排（4,104）。护罩（8,108）被设计成自支撑，使得其可以至少部分地吸收在操作过程中产生的离心力并在圆周方向上排出它们。

3. 发明申请

US20080269237A1 CARBAMIC ACID COMPOUNDS COMPRISING A PIPERAZINE LINKAGE AS HDAC INHIBITORS 有权
标题翻译：包含作为HDAC抑制剂的哌嗪连接物的碳酸化合物
公开(公告)号：US20080269237A1
公开(公告)日：2008-10-30
申请号：US12165686
申请日：2008-07-01
申请人： Clare J. WATKINS , Maria-Rosario Romero-Martin , James Ritchie , Paul W. Finn , Ivars Kalvinsh , Einars Loza , Klara Dikovska , Igor Starchenkov , Daina Lolya , Vija Gailite
发明人： Clare J. WATKINS , Maria-Rosario Romero-Martin , James Ritchie , Paul W. Finn , Ivars Kalvinsh , Einars Loza , Klara Dikovska , Igor Starchenkov , Daina Lolya , Vija Gailite
IPC分类号： A61K31/506 , A61K31/495 , A61P35/00 , C12N9/99 , A61P25/28 , A61P25/16
CPC分类号： C07D213/74 , C07D239/42 , C07D295/185 , C07D295/192 , C07D295/26 , C07D317/58 , C07D333/60
摘要： This invention pertains to certain carbamic acid compounds which inhibit HDAC (histone deacetylase) activity of the following formula: The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc.
摘要翻译：本发明涉及抑制下式的HDAC（组蛋白脱乙酰酶）活性的某些氨基甲酸化合物：本发明还涉及包含这些化合物的药物组合物，以及这些化合物和组合物在体外和体内的用途抑制HDAC，以及治疗由HDAC，癌症，增殖性病症，牛皮癣等介导的病症。

4. 发明申请

US20070231143A1 BLADE WITH SHROUD 有权
标题翻译：刮胡子
公开(公告)号：US20070231143A1
公开(公告)日：2007-10-04
申请号：US11682624
申请日：2007-03-06
申请人： Andreas Boegli , James Ritchie
发明人： Andreas Boegli , James Ritchie
IPC分类号： F01D5/22
CPC分类号： F01D5/225
摘要： A blade for a turbo machine has a blade section and a shroud element terminating the blade section in the blade section longitudinal direction. The blade section has a suction face and a pressure face. The shroud element extends essentially at right angles to the blade section longitudinal direction and has a first platform section projecting beyond the blade section and a second platform section projecting beyond the blade section. The platform sections are asymmetric with respect to one another. At least the first platform section of the shroud element is arranged at an additional inclination angle with respect to a normal alignment of the first platform section, with the additional inclination angle being in the opposite direction to the bending torque which acts on the first platform section during operation.
摘要翻译：用于涡轮机的叶片具有叶片部分和在叶片部分纵向方向上终止叶片部分的护罩元件。叶片部分具有吸力面和压力面。护罩元件基本上与叶片部分纵向方向成直角地延伸，并且具有突出超过叶片部分的第一平台部分和突出超过叶片部分的第二平台部分。平台部分相对于彼此是不对称的。护罩元件的至少第一平台部分相对于第一平台部分的正常对准以额外的倾斜角度布置，附加倾斜角度与作用在第一平台部分上的弯曲扭矩相反的方向在运行期间。

5. 发明申请

US20060105464A1 Quantitative determination of analyte 审中-公开
标题翻译：分析物的定量测定
公开(公告)号：US20060105464A1
公开(公告)日：2006-05-18
申请号：US10988069
申请日：2004-11-12
申请人： Jorg Friedrich Weber , John Rizzo , James Ritchie , Alan Berry , Allen Godwin
发明人： Jorg Friedrich Weber , John Rizzo , James Ritchie , Alan Berry , Allen Godwin
IPC分类号： G01N33/00
CPC分类号： G01N31/22 , C07C29/16 , Y10T436/200833
摘要： The invention relates to an analytical technique for the quantitative determination of an analyte and a reagent solution useful in said quantitative determination. The analytical technique is conveniently adapted for quantitative determination of carbonyl and even more particularly adapted for finishing an alcohol produced in the Oxo Process.
摘要翻译：本发明涉及用于定量测定所述定量测定中所用分析物和试剂溶液的分析技术。分析技术方便地适用于羰基的定量测定，甚至更特别适用于在Oxo方法中生产的醇。

6. 发明申请

US20050143385A1 Carbamic acid compounds comprising a piperazine linkage as hdac inhibitors 失效
公开(公告)号：US20050143385A1
公开(公告)日：2005-06-30
申请号：US10509732
申请日：2003-04-03
申请人： Clare Watkins , Maria-Rosario Romero-Martin , James Ritchie , Paul Finn , Ivars Kalvinsh , Einars Loza , Klar Dikovska , Igor Starchenkov , Daina Lolya , Vija Gailite
发明人： Clare Watkins , Maria-Rosario Romero-Martin , James Ritchie , Paul Finn , Ivars Kalvinsh , Einars Loza , Klar Dikovska , Igor Starchenkov , Daina Lolya , Vija Gailite
IPC分类号： C07D295/16 , A61K31/495 , A61K31/496 , A61K31/506 , A61P17/06 , A61P35/00 , A61P43/00 , C07D209/14 , C07D209/16 , C07D209/18 , C07D209/42 , C07D213/36 , C07D213/74 , C07D239/42 , C07D241/04 , C07D295/18 , C07D295/185 , C07D295/192 , C07D295/22 , C07D295/26 , C07D317/58 , C07D333/60 , C07D43/02
CPC分类号： C07D213/74 , C07D239/42 , C07D295/185 , C07D295/192 , C07D295/26 , C07D317/58 , C07D333/60
摘要： This invention pertains to certain carbamic acid compounds which inhibit HDAC (histone deacetylase) activity of the following formula: wherein: Cy is independently a cyclyl group; Q1 is independently a covalent bond or cyclyl leader group; the piperazin-1,4-diyl group is optionally substituted; J1 is independently a covalent bond or —C(═;O)—; J2 is independently —C(═O)— or —S(═O)2—; Q2 is independently an acid leader group; wherein: Cy is independently: C3-20carbocyclyl, C3-20heterocyclyl, or C5-20aryl; and is optionally substituted; Q1 is independently: a covalent bond; C1-7alkylene; or C1-7alkylene-X—C1-7alkylene, —X—C1-7alkylene, or C1-7alkylene-X—, wherein X is —O— or —S—; and is optionally substituted; Q2 is independently: C4-8alkylene; and is optionally substituted; and has a backbone length of at least 4 atoms; or: Q2 is independently: C5-20arylene; C5-20arylene-C1-7alkylene; C1-7alkylene-C5-20arylene; or, C1-7alkylene-C5-20arylene-C1-7alkylene; and is optionally substituted; and has a backbone length of at least 4 atoms; or a pharmaceutically acceptable salt, solvate, amide, ester, ether, chemically protected form, or prodrug thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc.

7. 发明申请

US20050119508A1 Cobalt flash process 失效
标题翻译：钴闪光过程
公开(公告)号：US20050119508A1
公开(公告)日：2005-06-02
申请号：US10508925
申请日：2003-03-28
申请人： Dominic Clausi , Eddy van Driesche , Ronald Garton , James Ritchie , Nico de Munck
发明人： Dominic Clausi , Eddy van Driesche , Ronald Garton , James Ritchie , Nico de Munck
IPC分类号： C07C29/16 , C07C45/50 , C07C45/49
CPC分类号： C07C45/50 , C07C29/16 , C07C31/125 , C07C31/12 , C07C47/02
摘要： The Cobalt Flash Process is modified by replacing formic acid with acetic acid as process acid. Efficiency using acetic acid as process acid is achieved by two improvements which may be added separately and independently: (1) separation of acetic acid and water from the condensate distilled off in the cobalt salt concentration stage; and (2) removal of formic acid from the system by reaction with the product alcohol in the preformer.
摘要翻译：通过用乙酸代替甲酸作为加工酸来改变钴闪蒸工艺。使用乙酸作为加工酸的效率通过两个改进实现，其可以单独和独立地添加：（1）在钴盐浓缩阶段从蒸馏出的冷凝物中分离出乙酸和水; 和（2）通过与预成型剂中的产物醇反应从体系中除去甲酸。

8. 发明授权

US07946017B2 Integrated hinge and temporary door checker 失效
标题翻译：综合铰链和临时门检查
公开(公告)号：US07946017B2
公开(公告)日：2011-05-24
申请号：US12749201
申请日：2010-03-29
申请人： Mark Brown , Marc Iman , Cindy Tran , James Ritchie , Takahiro Ohno , Takashi Ogawa , Takeshi Ishikawa
发明人： Mark Brown , Marc Iman , Cindy Tran , James Ritchie , Takahiro Ohno , Takashi Ogawa , Takeshi Ishikawa
IPC分类号： B23P19/00
CPC分类号： E05D11/1042 , E05F1/1238 , E05Y2900/531 , Y10T16/5383 , Y10T16/540257 , Y10T16/54028 , Y10T16/54029 , Y10T16/625 , Y10T16/6295 , Y10T29/49815 , Y10T29/49824 , Y10T29/49826
摘要： A temporary checking device is provided that works in conjunction with elements of a vehicle hinge that remain in the vehicle's final configuration. The hinge includes a hinge pin rotatably connecting a door hinge bracket to a pillar hinge bracket. The checking device includes a spring portion that is disposed between the door hinge bracket and the pillar hinge bracket. The spring portion is compressed during movement of the door hinge bracket relative to the pillar hinge bracket from either of two rest positions. The spring portion urges the vehicle door affixed thereto back into one of the rest positions, thus allowing manufacturing operations such as painting, etc., to be performed on the vehicle.
摘要翻译：提供临时检查装置，其与保持在车辆最终配置中的车辆铰链的元件一起工作。铰链包括将门铰链支架可旋转地连接到支柱铰链支架的铰链销。检查装置包括设置在门铰链支架和支柱铰链支架之间的弹簧部分。在门铰链支架相对于支柱铰链支架从两个静止位置中的任一个移动期间，弹簧部分被压缩。弹簧部分促使车门被固定回到其中一个休息位置，从而允许在车辆上执行诸如喷漆等的制造操作。

9. 发明申请

US20110105572A1 CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS 审中-公开
标题翻译：包含作为HDAC抑制剂的酰胺链接的碳酸化合物
公开(公告)号：US20110105572A1
公开(公告)日：2011-05-05
申请号：US12983971
申请日：2011-01-04
申请人： Clare J. Watkins , Maria Rosario Romero-Martin , Kathryn G. Moore , James Ritchie , Paul W. Finn , Ivars Kalvinsh , Einars Loza , Igor Starchenkov , Klara Dikovska , Rasma M. Bokaldere , Vija Gailite , Maxim Vorona , Victor Andrianov , Daina Lolya , Valentina Semenikhina , Andris Amolins , C. John Harris , James E.S. Duffy
发明人： Clare J. Watkins , Maria Rosario Romero-Martin , Kathryn G. Moore , James Ritchie , Paul W. Finn , Ivars Kalvinsh , Einars Loza , Igor Starchenkov , Klara Dikovska , Rasma M. Bokaldere , Vija Gailite , Maxim Vorona , Victor Andrianov , Daina Lolya , Valentina Semenikhina , Andris Amolins , C. John Harris , James E.S. Duffy
IPC分类号： A61K31/165 , C07C259/06 , C07C259/08 , A61K31/167 , C07D317/60 , A61K31/36 , C07D213/56 , A61K31/4409 , C07D307/54 , A61K31/341 , A61K31/166 , C07D271/08 , A61K31/4245 , C07D207/337 , A61K31/40 , A61K31/4406 , C07D209/20 , A61K31/405 , C07D333/24 , A61K31/381 , A61P35/00 , C12N5/02
CPC分类号： C07D207/337 , A61K31/16 , A61K31/195 , A61K31/198 , A61K31/277 , A61K31/38 , A61K31/381 , A61K31/426 , C07C233/49 , C07C233/83 , C07C235/34 , C07C237/36 , C07C255/57 , C07C259/06 , C07C259/08 , C07C2603/18 , C07D207/40 , C07D207/404 , C07D209/14 , C07D209/16 , C07D209/18 , C07D209/22 , C07D213/06 , C07D213/55 , C07D213/56 , C07D233/04 , C07D233/08 , C07D235/14 , C07D235/24 , C07D271/06 , C07D307/34 , C07D307/54 , C07D317/60 , C07D333/24 , C07D333/60 , C07D403/12 , Y02A50/411
摘要： This invention pertains to certain active carbamic acid compounds which inhibit HDAC activity and which have the following formula: wherein: A is a C5-20heteroaryl or C5-20carboaryl group and is optionally substituted; Q1 is a C2-7alkylene group having a backbone of at least 2 carbon atoms, and is optionally substituted; J is —N(R1)C(═O)— or —C(═O)N(R1)—; R1 is hydrogen, C1-7alkyl, C3-20heterocyclyl, or C5-20aryl; and, Q2 is C1-7alkylene, C5-20arylene, C5-20arylene-C1-7alkylene, or C1-7alkylene-C5-20arylene having a backbone of at least 3 carbon atoms, and is optionally substituted; and pharmaceutically acceptable salts thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and, e.g., to treat proliferative conditions, such as cancer and psoriasis.
摘要翻译：本发明涉及一些抑制HDAC活性的活性氨基甲酸化合物，其具有下式：其中：A为C 5-20杂芳基或C 5-20碳氢芳基并且任选被取代; Q1是具有至少2个碳原子的主链的C2-7亚烷基，并且任选被取代; J是-N（R 1）C（= O） - 或-C（= O）N（R 1） - ; R 1是氢，C 1-7烷基，C 3-20杂环基或C 5-20芳基; 并且Q2是具有至少3个碳原子的主链的C 1-7亚烷基，C 5-20亚芳基，C 5-20亚芳基-C 1-7亚烷基或C 1-7亚烷基-C 5-20亚芳基，并且任选被取代; 及其药学上可接受的盐。本发明还涉及包含这些化合物的药物组合物，以及这些化合物和组合物在体外和体内的用途，以抑制HDAC，并且例如治疗增殖性疾病如癌症和牛皮癣。

10. 发明授权

US07874791B2 Turbomachine 有权
标题翻译：涡轮机
公开(公告)号：US07874791B2
公开(公告)日：2011-01-25
申请号：US11530065
申请日：2006-09-08
申请人： Joergen Ferber , James Ritchie
发明人： Joergen Ferber , James Ritchie
IPC分类号： F01D5/22 , F01D9/04 , F01D5/30
CPC分类号： F01D5/225 , F05D2240/40 , F05D2260/30 , Y02T50/672 , Y02T50/673
摘要： A turbomachine (1), in particular a turbine or compressor, includes a rotor (2) which has at least one moving blade row (4) with a plurality of moving blades (5), and a stator (3) which has at least one guide vane row (6) with a plurality of guide vanes (7), at least in one of the blade or vane rows (4, 6) all the blades or vanes (5, 7) each having a shroud plate (10). In order to simplify the maintenance of the turbo-machine (1), the shroud plates (10) are separate components with respect to the respective blade or vane (5, 7) and are mounted on the respective blade or vane (5, 7), shroud plates (10) adjacent in the circumferential direction (9) being coupled to one another for the transmission of tensile forces in the circumferential direction (9).
摘要翻译：涡轮机（1），特别是涡轮机或压缩机，包括具有至少一个具有多个活动叶片（5）的至少一个活动叶片排（4）的转子（2）和至少具有至少具有多个导向叶片（7）的一个导向叶片排（6），至少在叶片或叶片排（4,6）之一中，所有叶片或叶片（5,7）均具有护罩板（10）。为了简化涡轮机（1）的维护，护罩板（10）相对于相应的叶片或叶片（5,7）是分离的部件，并且安装在相应的叶片或叶片（5,7）上），沿圆周方向（9）相邻的护罩板（10）彼此联接以在周向（9）上传递张力。

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