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1. 发明授权

US08079959B2 Patient screening tools for implantable cardiac stimulus systems 有权
标题翻译：用于可植入心脏刺激系统的患者筛查工具
公开(公告)号：US08079959B2
公开(公告)日：2011-12-20
申请号：US12196779
申请日：2008-08-22
申请人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
发明人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
IPC分类号： A61B5/02
CPC分类号： A61B5/0402 , A61B5/04012 , A61B5/04023 , A61B5/6823 , A61B5/742 , A61N1/372
摘要： Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation.
摘要翻译：提供工具和装置，用于通过分析使用外部或皮肤电极捕获的心脏信号来确定患者是否非常适合于接收可植入心脏刺激装置。一些说明性工具包括用于与印刷的ECG条的视觉比较的形状。还公开了自动装置，其为用户以电子方式执行至少一些分析功能。在一个示例中，将印刷的ECG条与形状进行视觉比较，以确保患者非常适合于接收具有特定植入位置和/或心脏信号分析方法实现的心脏刺激装置。

2. 发明申请

US20090054796A1 Patient Screening Tools for Implantable Cardiac Stimulus Systems 有权
标题翻译：用于可植入心脏刺激系统的患者筛选工具
公开(公告)号：US20090054796A1
公开(公告)日：2009-02-26
申请号：US12196779
申请日：2008-08-22
申请人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
发明人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
IPC分类号： A61B5/0402
CPC分类号： A61B5/0402 , A61B5/04012 , A61B5/04023 , A61B5/6823 , A61B5/742 , A61N1/372
摘要： Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation.
摘要翻译：提供工具和装置，用于通过分析使用外部或皮肤电极捕获的心脏信号来确定患者是否非常适合于接收可植入心脏刺激装置。一些说明性工具包括用于与印刷的ECG条的视觉比较的形状。还公开了自动装置，其为用户以电子方式执行至少一些分析功能。在一个示例中，将印刷的ECG条与形状进行视觉比较，以确保患者非常适合于接收具有特定植入位置和/或心脏信号分析方法实现的心脏刺激装置。

3. 发明申请

US20120316613A1 Antitachycardia Pacing Pulse from a Subcutaneous Defibrillator 有权
标题翻译：来自皮下除颤器的抗心动过速起搏脉冲
公开(公告)号：US20120316613A1
公开(公告)日：2012-12-13
申请号：US13491492
申请日：2012-06-07
申请人： James M. Keefe , Rick Sanghera
发明人： James M. Keefe , Rick Sanghera
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/0504 , A61N1/3756 , A61N1/3962
摘要： Devices and methods for single therapy pulse (STP) therapy for tachyarrythmia are disclosed. The STP therapy can be delivered from a far-field position to allow a “global” capture approach to pacing. Due to the global capture in STP, a series of pulses, which is indicative of conventional anti-tachycardia pacing (ATP) delivered by transvenous systems, becomes unnecessary. One to four pulses at most are needed for STP, and after delivery of the one to four pulses, therapy delivery can be interrupted to determine whether the previously delivered therapy has been successful.
摘要翻译：公开了单速治疗脉搏（STP）治疗高血压的装置和方法。 STP治疗可以从远场发送，以允许全局捕获方式进行起搏。由于在STP中的全球捕获，一系列脉冲表示由经静脉系统递送的传统的抗心动过速起搏（ATP），这是不必要的。 STP需要一至四个脉冲，并且在输送一到四个脉冲之后，可以中断治疗递送以确定先前传递的治疗是否已经成功。

4. 发明申请

US20120071773A1 Patient Screening Tools for Implantable Cardiac Stimulus Systems 审中-公开
标题翻译：用于可植入心脏刺激系统的患者筛选工具
公开(公告)号：US20120071773A1
公开(公告)日：2012-03-22
申请号：US13308281
申请日：2011-11-30
申请人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
发明人： Rick Sanghera , Alan F. Marcovecchio , James M. Keefe
IPC分类号： A61B5/04
CPC分类号： A61B5/0402 , A61B5/04012 , A61B5/04023 , A61B5/6823 , A61B5/742 , A61N1/372
摘要： Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Kits for use of illustrative tools are also shown. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation.
摘要翻译：提供工具和装置，用于通过分析使用外部或皮肤电极捕获的心脏信号来确定患者是否非常适合于接收可植入心脏刺激装置。一些说明性工具包括用于与印刷的ECG条的视觉比较的形状。还显示了使用说明性工具的套件。还公开了自动装置，其为用户以电子方式执行至少一些分析功能。在一个示例中，将印刷的ECG条与形状进行视觉比较，以确保患者非常适合于接收具有特定植入位置和/或心脏信号分析方法实现的心脏刺激装置。

5. 发明授权

US09849291B2 Antitachycardia pacing pulse from a subcutaneous defibrillator 有权
公开(公告)号：US09849291B2
公开(公告)日：2017-12-26
申请号：US13491492
申请日：2012-06-07
申请人： James M. Keefe , Rick Sanghera
发明人： James M. Keefe , Rick Sanghera
IPC分类号： A61N1/00 , A61N1/362 , A61N1/39 , A61N1/05 , A61N1/375
CPC分类号： A61N1/3622 , A61N1/0504 , A61N1/3756 , A61N1/3962
摘要： Devices and methods for single therapy pulse (STP) therapy for tachyarrythmia are disclosed. The STP therapy can be delivered from a far-field position to allow a “global” capture approach to pacing. Due to the global capture in STP, a series of pulses, which is indicative of conventional anti-tachycardia pacing (ATP) delivered by transvenous systems, becomes unnecessary. One to four pulses at most are needed for STP, and after delivery of the one to four pulses, therapy delivery can be interrupted to determine whether the previously delivered therapy has been successful.

6. 发明授权

US08437838B2 Methods and devices for identifying overdetection of cardiac signals 有权
标题翻译：识别心脏信号过度检测的方法和装置
公开(公告)号：US08437838B2
公开(公告)日：2013-05-07
申请号：US13607256
申请日：2012-09-07
申请人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
发明人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
IPC分类号： A61B5/04 , A61B5/02 , A61N1/00
CPC分类号： A61B5/0452 , A61B5/0424 , A61B5/726
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, sensed data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在说明性示例中，分析包括检测到的事件的感测数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。

7. 发明授权

US08244349B2 Adaptive shock delivery in an implantable cardiac stimulus device 有权
标题翻译：可植入心脏刺激装置中的自适应冲击输送
公开(公告)号：US08244349B2
公开(公告)日：2012-08-14
申请号：US12363425
申请日：2009-01-30
申请人： Rick Sanghera , Jay A. Warren
发明人： Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3686
摘要： Methods and devices that are configured to deliver cardiac stimuli in a particular fashion. In an illustrative embodiment, a method is used wherein a first stimulus is delivered using a first polarity, and, if the first stimulus fails to successfully convert an arrhythmia, a second stimulus having a second polarity that is different from or opposite of the first polarity is then delivered. Subsequent stimuli, if needed, are delivered in a continuing alternating-polarity manner. The first polarity may be determined by observing whether successfully-converting stimulus has been delivered previously and, if so, the polarity of the most recent stimulus that resulted in successful conversion is used as the first polarity. In additional embodiments, electrode configuration may be changed instead of or in addition to polarity, following unsuccessful stimulus delivery. Devices configured to perform such methods are included in additional illustrative embodiments.
摘要翻译：被配置为以特定方式递送心脏刺激的方法和装置。在说明性实施例中，使用其中使用第一极性传送第一刺激的方法，并且如果第一刺激不能成功转换心律失常，则具有与第一极性不同或相反的第二极性的第二刺激然后交付。如果需要，随后的刺激以连续的交替极性方式递送。第一极性可以通过观察成功转换刺激是否已经被传递来确定，如果是，则将导致成功转换的最近的刺激的极性用作第一极性。在另外的实施例中，在不成功的刺激递送之后，可以改变电极配置而不是极性或除了极性之外。被配置为执行这些方法的装置包括在另外的说明性实施例中。

8. 发明申请

US20120197334A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20120197334A1
公开(公告)日：2012-08-02
申请号：US13436448
申请日：2012-03-30
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
IPC分类号： A61N1/365
CPC分类号： A61B5/4836 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61N1/3621 , A61N1/36514 , A61N1/36592 , A61N1/37 , A61N1/3987
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。几个例子强调使用与静态模板和/或事件间相关分析相关的形态分析。

9. 发明申请

US20100331904A1 Adaptive Confirmation of Treatable Arrhythmia in Implantable Cardiac Stimulus Devices 有权
标题翻译：可植入心脏刺激装置中可治疗性心律失常的自适应确认
公开(公告)号：US20100331904A1
公开(公告)日：2010-12-30
申请号：US12826241
申请日：2010-06-29
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/39 , A61N1/365
CPC分类号： A61N1/3987 , A61B5/0464 , A61N1/3622 , A61N1/3925 , A61N1/3943 , A61N1/3956
摘要： Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.
摘要翻译：用于通过在初始识别可治疗病症后观察心脏活动来调整可植入心脏刺激装置中的治疗递送决定的方法和装置。在一些实例中，显示良性的心脏活动被定量，并且根据在可治疗病症的初始鉴定之后看到多少明显良性的心脏活动来调整治疗确认阈值。在其他示例中，在可治疗条件的初始识别之后应用新阈值，从随后的治疗递送决定中移除初始识别之前的历史数据。

10. 发明申请

US20100152799A1 Implantable Defibrillator Systems and Methods with Mitigations for Saturation Avoidance and Accommodation 有权
标题翻译：植入式除颤器系统和缓解饱和度的住院方法
公开(公告)号：US20100152799A1
公开(公告)日：2010-06-17
申请号：US12636575
申请日：2009-12-11
申请人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
发明人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
IPC分类号： A61N1/39
CPC分类号： A61N1/3704 , A61N1/048 , A61N1/0504 , A61N1/0563 , A61N1/3702 , A61N1/3968 , A61N1/3987
摘要： Methods and implantable devices that address response to, or avoidance of, likely non-cardiac voltages including afterpotentials from external or internal stimulus. Some examples are directed toward methods of operation in implantable medical devices, the methods configured for identifying saturation of input circuitry and mitigating the effects of such saturation. Some examples are directed toward implantable cardiac stimulus or monitoring devices that include methods for identifying saturated conditions and mitigating the effects of such saturation.
摘要翻译：解决可能的非心脏电压（包括来自外部或内部刺激的后电位）的响应或避免的方法和可植入装置。一些示例涉及可植入医疗设备中的操作方法，该方法被配置用于识别输入电路的饱和度并减轻这种饱和的影响。一些示例涉及可植入心脏刺激或监测装置，其包括用于识别饱和状况和减轻这种饱和的影响的方法。

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