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1. 发明授权

US08969816B2 Board-level partitioning in MR-PET imaging system integration 有权
标题翻译： MR-PET成像系统集成中的板级划分
公开(公告)号：US08969816B2
公开(公告)日：2015-03-03
申请号：US13186891
申请日：2011-07-20
申请人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
发明人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
IPC分类号： G01T1/164 , G01T1/24 , A61B5/05 , G01R33/28 , G01R33/48 , A61B6/00 , A61B5/055 , A61B6/03
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： A printed circuit board (PCB) assembly of a data processing unit for an integrated magnetic resonance (MR) and positron emission tomography (PET) system, the PCB assembly includes a plurality of PCB layers disposed in a stacked arrangement, first and second PET signal processing circuits carried by a first layer of the plurality of PCB layers, first and second ground plane structures carried by a second layer of the plurality of PCB layers and configured relative to the first and second PET signal processing circuits, respectively, and a ground partition that separates the first PET signal processing circuit from the second PET signal processing circuit on the first layer. The ground partition extends through the first layer to provide electromagnetic interference (EMI) shielding between the first and second PET signal processing circuits.
摘要翻译：一种用于集成磁共振（MR）和正电子发射断层摄影（PET）系统的数据处理单元的印刷电路板（PCB）组件，PCB组件包括以堆叠布置设置的多个PCB层，第一和第二PET信号由多个PCB层的第一层承载的处理电路，由多个PCB层的第二层承载并分别相对于第一和第二PET信号处理电路配置的第一和第二接地平面结构以及接地分区其将第一PET信号处理电路与第一PET信号处理电路分离在第一层上。接地分隔件延伸穿过第一层，以在第一和第二PET信号处理电路之间提供电磁干扰（EMI）屏蔽。

2. 发明申请

US20120022364A1 Board-Level Partitioning in MR-PET Imaging System Integration 有权
标题翻译： MR-PET成像系统集成中的板级分区
公开(公告)号：US20120022364A1
公开(公告)日：2012-01-26
申请号：US13186891
申请日：2011-07-20
申请人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
发明人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
IPC分类号： A61B6/00 , H05K9/00
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： A printed circuit board (PCB) assembly of a data processing unit for an integrated magnetic resonance (MR) and positron emission tomography (PET) system, the PCB assembly includes a plurality of PCB layers disposed in a stacked arrangement, first and second PET signal processing circuits carried by a first layer of the plurality of PCB layers, first and second ground plane structures carried by a second layer of the plurality of PCB layers and configured relative to the first and second PET signal processing circuits, respectively, and a ground partition that separates the first PET signal processing circuit from the second PET signal processing circuit on the first layer. The ground partition extends through the first layer to provide electromagnetic interference (EMI) shielding between the first and second PET signal processing circuits.
摘要翻译：一种用于集成磁共振（MR）和正电子发射断层摄影（PET）系统的数据处理单元的印刷电路板（PCB）组件，PCB组件包括以堆叠布置设置的多个PCB层，第一和第二PET信号由多个PCB层的第一层承载的处理电路，由多个PCB层的第二层承载并分别相对于第一和第二PET信号处理电路配置的第一和第二接地平面结构以及接地分区其将第一PET信号处理电路与第一PET信号处理电路分离在第一层上。接地分隔件延伸穿过第一层，以在第一和第二PET信号处理电路之间提供电磁干扰（EMI）屏蔽。

3. 发明授权

US08369928B2 Data processing system for multi-modality imaging 有权
标题翻译：多模态成像数据处理系统
公开(公告)号：US08369928B2
公开(公告)日：2013-02-05
申请号：US12564635
申请日：2009-09-22
申请人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
发明人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
IPC分类号： A61B5/05
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译：描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。

4. 发明申请

US20120018643A1 Dual Amplifier For MR-PET Hybrid Imaging System 有权
标题翻译： MR-PET混合成像系统的双路放大器
公开(公告)号：US20120018643A1
公开(公告)日：2012-01-26
申请号：US13186950
申请日：2011-07-20
申请人： James Frank Caruba , Roger E. Arseneau
发明人： James Frank Caruba , Roger E. Arseneau
IPC分类号： G01T1/161 , G01R33/28
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： PET signals are amplified in a hybrid PET/MR system. An amplifier structure is provided for operation in the magnetic field of the MR magnets. By filtering to remove signals at the MR frequency (e.g., about 123 MHz) as part of the amplification circuit, the amplification circuit may be positioned within the RF cabin, within the magnetic field, and even within a same housing as the MR magnets. MR interference may be reduced by staged amplification. The filtering may be bi-directional, such as using parallel and series traps. Digitization of the PET signals may be provided within the magnetic field with no or little interference with MR operation.
摘要翻译： PET信号在混合PET / MR系统中被放大。提供了用于在MR磁体的磁场中操作的放大器结构。通过滤波以除去作为放大电路的一部分的MR频率（例如，约123MHz）的信号，放大电路可以位于RF舱内，在磁场内，甚至在与MR磁体相同的外壳内。可以通过分阶段放大来减少MR干扰。滤波可以是双向的，例如使用并联和串联阱。可以在磁场内提供PET信号的数字化，而对MR操作没有或几乎没有干扰。

5. 发明申请

US20100076300A1 DATA PROCESSING SYSTEM FOR MULTI-MODALITY IMAGING 有权
标题翻译：用于多模式成像的数据处理系统
公开(公告)号：US20100076300A1
公开(公告)日：2010-03-25
申请号：US12564635
申请日：2009-09-22
申请人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
发明人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
IPC分类号： A61B5/055
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译：描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。

6. 发明授权

US08921796B1 Multiple discriminator PET with pileup event detection 有权
标题翻译：多重鉴别器PET与堆积事件检测
公开(公告)号：US08921796B1
公开(公告)日：2014-12-30
申请号：US14010953
申请日：2013-08-27
申请人： Roger E. Arseneau , James Frank Caruba
发明人： Roger E. Arseneau , James Frank Caruba
IPC分类号： G01T1/10 , G01T1/29
CPC分类号： G01T1/2985 , G01T1/171
摘要： A positron emission tomography (PET) system includes a PET detector configured to generate energy signals indicative of a set of events at the PET detector, a first discriminator coupled to the PET detector and configured to generate a primary timing signal in response to a primary event of the set of events, a second, derivative-based discriminator coupled to the PET detector and configured to generate a pileup timing signal in response to a piled-up event of the set of events, and a logic circuit to gate the primary and pileup timing signals of the first and second discriminators.
摘要翻译：正电子发射断层摄影（PET）系统包括PET检测器，其被配置为产生指示PET检测器处的一组事件的能量信号;耦合到PET检测器的第一鉴别器，并且被配置为响应于主要事件产生主定时信号的一组事件，第二个基于导数的鉴别器，耦合到PET检测器并且被配置为响应于该事件集合的堆叠事件产生堆积定时信号，以及逻辑电路，用于对初级和堆积第一和第二鉴别器的定时信号。

7. 发明授权

US08378306B2 Dual amplifier for MR-PET hybrid imaging system 有权
标题翻译：用于MR-PET混合成像系统的双放大器
公开(公告)号：US08378306B2
公开(公告)日：2013-02-19
申请号：US13186950
申请日：2011-07-20
申请人： James Frank Caruba , Roger E. Arseneau
发明人： James Frank Caruba , Roger E. Arseneau
IPC分类号： G01T1/10
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： PET signals are amplified in a hybrid PET/MR system. An amplifier structure is provided for operation in the magnetic field of the MR magnets. By filtering to remove signals at the MR frequency (e.g., about 123 MHz) as part of the amplification circuit, the amplification circuit may be positioned within the RF cabin, within the magnetic field, and even within a same housing as the MR magnets. MR interference may be reduced by staged amplification. The filtering may be bi-directional, such as using parallel and series traps. Digitization of the PET signals may be provided within the magnetic field with no or little interference with MR operation.
摘要翻译： PET信号在混合PET / MR系统中被放大。提供了用于在MR磁体的磁场中操作的放大器结构。通过滤波以除去作为放大电路的一部分的MR频率（例如，约123MHz）的信号，放大电路可以位于RF舱内，在磁场内，甚至在与MR磁体相同的外壳内。可以通过分阶段放大来减少MR干扰。滤波可以是双向的，例如使用并联和串联阱。可以在磁场内提供PET信号的数字化，没有或几乎没有MR操作的干扰。

8. 发明授权

US07323691B1 Methods and apparatus for protecting against X-ray infiltration in a SPECT scanner 有权
标题翻译：用于在SPECT扫描仪中防止X射线渗透的方法和装置
公开(公告)号：US07323691B1
公开(公告)日：2008-01-29
申请号：US11519411
申请日：2006-09-12
申请人： James Frank Caruba , Roger E. Arseneau
发明人： James Frank Caruba , Roger E. Arseneau
IPC分类号： G01T1/16
CPC分类号： G01T1/1615
摘要： Methods and apparatus provide for determining whether X-rays produced by a computer tomography (CT) scanner have infiltrated a single photon emission computed tomography (SPECT) scanner and shutting down at least one of a power source to one or more photo-multiplier tubes (PMTs) of the SPECT scanner, and an X-ray source of the CT scanner, when the determination is affirmative.
摘要翻译：方法和装置提供用于确定由计算机断层摄影（CT）扫描仪产生的X射线是否渗透了单个光子发射计算机断层摄影（SPECT）扫描器并且将至少一个电源关闭到一个或多个光电倍增管（ PMT）和CT扫描仪的X射线源，当确定是肯定的。

9. 发明授权

US4692890A Method and integrator circuit for integrating signals, in particular for scintillation gamma camera 失效
标题翻译：用于集成信号的方法和积分电路，特别是用于闪烁γ照相机
公开(公告)号：US4692890A
公开(公告)日：1987-09-08
申请号：US614886
申请日：1984-05-29
申请人： Roger E. Arseneau
发明人： Roger E. Arseneau
IPC分类号： G01T1/164 , G06F7/544 , G06G7/18 , G06J1/00 , G06F7/38
CPC分类号： G01T1/1642 , G06F7/544
摘要： A method and integrator circuit for digitally integrating signals wherein digital signals to be integrated are supplied to a digital adder thereby generating digital adder output signals. Each digital adder output signal is stored and the stored digital adder output signal is refed to the digital adder. Each refed stored digital adder output signal is then added by the adder to a succeeding digital signal supplied to the adder for integration. In a preferred embodiment of the invention, the digital signals are analog-to-digital converted signals produced by a radiation detector, such as a scintillation gamma camera, generated from radiation impinging on the radiation detector.
摘要翻译：一种用于数字积分信号的方法和积分器电路，其中要被积分的数字信号被提供给数字加法器，从而产生数字加法器输出信号。存储每个数字加法器输出信号，并将存储的数字加法器输出信号提供给数字加法器。每个被重新存储的数字加法器输出信号然后由加法器加到提供给加法器的后续数字信号进行积分。在本发明的一个优选实施例中，数字信号是由辐射检测器产生的模数转换信号，例如由照射在辐射检测器上的辐射产生的闪烁γ照相机。

10. 发明授权

US4323977A Non-uniformity energy correction method and apparatus 失效
标题翻译：不均匀性能量校正方法及装置
公开(公告)号：US4323977A
公开(公告)日：1982-04-06
申请号：US96181
申请日：1979-11-20
申请人： Roger E. Arseneau
发明人： Roger E. Arseneau
IPC分类号： G01T1/164 , G01T1/20
CPC分类号： G01T1/1642 , A61B6/4258
摘要： A method and apparatus are disclosed for correcting energy (Z) signal non-uniformities in the response of an Anger-type scintillation camera to image events occurring at different (X, Y) positions on the camera face. Energy correction factors f(P)' corresponding to deviations of up to .+-.12.8% from a reference pixel area are determined off-line for 4,096 camera face pixel areas from a uniform flood field source Z-map. The correction factors f(P)' are stored in a 64.times.64 array of a correction factor memory, addressable by image event (X, Y) position coordinates. During on-line operation, for each image event the correction factor f(P)' corresponding to the image event (X, Y) position is retrieved, scaled in a multiplying digital to analog converter by the actual energy Z.sub.IN of the event, and added to the event Z.sub.IN signal to provide a corrected energy signal Z.sub.c =Z.sub.IN (1+f(P)') which is proportional to the incoming signal. The corrected energy signal is then applied to a fixed energy window analyzer to determine acceptance or rejection of the event. The invention is especially advantageous for correcting energy non-linearities in the detection of single source with multiple energy levels and multiple sources with different energy levels.
摘要翻译：公开了一种用于校正愤怒型闪烁照相机响应中的能量（Z）信号不均匀性以在相机面上的不同（X，Y）位置处发生的图像事件的方法和装置。对于来自均匀洪水源Z图的4,096个摄像机面像素区域离线地确定对应于参考像素区域的+/- 12.8％的偏差的能量校正因子f（P）'。校正因子f（P）'存储在校正因子存储器的64×64阵列中，可通过图像事件（X，Y）位置坐标寻址。在在线操作期间，对于每个图像事件，检索对应于图像事件（X，Y）位置的校正因子f（P）'，在乘法数模转换器中按事件的实际能量ZIN进行缩放，以及添加到事件ZIN信号以提供与输入信号成比例的校正能量信号Zc = ZIN（1 + f（P）'）。然后将校正的能量信号施加到固定能量窗口分析器以确定事件的接受或拒绝。本发明特别有利于在具有多个能量级别的单个源和具有不同能级的多个源的检测中校正能量非线性。

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