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1. 发明授权

US08569491B2 Method for preparing entecavir and intermediate used therein 失效
标题翻译：制备恩替卡韦和中间体的方法
公开(公告)号：US08569491B2
公开(公告)日：2013-10-29
申请号：US13501414
申请日：2010-09-15
申请人： Jae Heon Lee , Gha Seung Park , Jin Hee Kim , Tae Jin Choi , Ji Eun Lee , Jung Hee Han , Hyo Jeong Bang , Sun Young Jung , Young Kil Chang , Gwan Sun Lee , Maeng Sup Kim
发明人： Jae Heon Lee , Gha Seung Park , Jin Hee Kim , Tae Jin Choi , Ji Eun Lee , Jung Hee Han , Hyo Jeong Bang , Sun Young Jung , Young Kil Chang , Gwan Sun Lee , Maeng Sup Kim
IPC分类号： C07D473/00
CPC分类号： C07D473/04
摘要： Disclosed are a novel, high-yield method for preparing entecavir and intermediates used therein.
摘要翻译：公开了用于制备恩替卡韦和中间体的新颖的高产率方法。

2. 发明申请

US20120202998A1 NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN 失效
标题翻译：用于制备ENTECAVIR和中间体的新方法
公开(公告)号：US20120202998A1
公开(公告)日：2012-08-09
申请号：US13501414
申请日：2010-09-15
申请人： Jae Heon Lee , Gha Seung Park , Jin Hee Kim , Tae Jin Choi , Ji Eun Lee , Jung Hee Han , Hyo Jeong Bang , Sun Young Jung , Young Kil Chang , Gwan Sun Lee , Maeng Sup Kim
发明人： Jae Heon Lee , Gha Seung Park , Jin Hee Kim , Tae Jin Choi , Ji Eun Lee , Jung Hee Han , Hyo Jeong Bang , Sun Young Jung , Young Kil Chang , Gwan Sun Lee , Maeng Sup Kim
IPC分类号： C07D473/18
CPC分类号： C07D473/04
摘要： Disclosed are a novel, high-yield method for preparing entecavir and intermediates used therein.
摘要翻译：公开了用于制备恩替卡韦和中间体的新颖的高产率方法。

3. 发明授权

US08569490B2 Intermediate and process for preparing entecavir using same 失效
标题翻译：使用相同方法制备恩替卡韦的中间体和方法
公开(公告)号：US08569490B2
公开(公告)日：2013-10-29
申请号：US13140640
申请日：2009-12-24
申请人： Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
发明人： Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
IPC分类号： C07D473/18 , C07F7/08 , C07C49/517
CPC分类号： C07D473/18
摘要： The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.
摘要翻译：本发明涉及一种制备恩替卡韦[1-S-（1α，3α，4α）] -2-氨基-1,9-二氢-9- [4-羟基 -3-（羟甲基）-2-亚甲基环戊基] -6H-嘌呤-6-酮，抗病毒剂及其中使用的新型中间体。

4. 发明申请

US20110251387A1 NOVEL INTERMEDIATE AND PROCESS FOR PREPARING ENTECAVIR USING SAME 失效
标题翻译：使用它的新型中间件和制备ENTECAVIR的方法
公开(公告)号：US20110251387A1
公开(公告)日：2011-10-13
申请号：US13140640
申请日：2009-12-24
申请人： Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
发明人： Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
IPC分类号： C07D473/18 , C07F7/08 , C07C49/517
CPC分类号： C07D473/18
摘要： The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.
摘要翻译：本发明涉及一种制备恩替卡韦[1-S-（1α，3α，4α] b] -2-氨基-1,9-二氢-9- [4- 羟基-3-（羟甲基）-2-亚甲基环戊基] -6H-嘌呤-6-酮，抗病毒剂及其中使用的新型中间体。

5. 发明申请

US20100249395A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN 失效
标题翻译：用于制备CAPECABABINE和用于其的BETA-异恶唑烷基碳酸酯化合物的方法
公开(公告)号：US20100249395A1
公开(公告)日：2010-09-30
申请号：US12742367
申请日：2008-11-07
申请人： Jaeheon Lee , Gha-Seung Park , Weon Ki Yang , Jin Hee Kim , Cheol Hyun Park , Yong-Hoon An , Yoon Ju Lee , Young-Kil Chang , Gwan Sun Lee
发明人： Jaeheon Lee , Gha-Seung Park , Weon Ki Yang , Jin Hee Kim , Cheol Hyun Park , Yong-Hoon An , Yoon Ju Lee , Young-Kil Chang , Gwan Sun Lee
IPC分类号： C07H19/06 , C07D307/20
CPC分类号： C07D405/04 , C07H1/00 , C07H19/06 , Y02P20/55
摘要： The present invention relates to a method for preparing capecitabine and a method for preparing a β-anomer-rich trialkyl carbonate compound used therein, and a highly pure capecitabine can be efficiently prepared with a high yield by the method of the present invention using the β-anomer-rich trialkyl carbonate compound as an intermediate.
摘要翻译：本发明涉及一种制备卡培他滨的方法和一种制备其中使用的富含甘油的三烷基碳酸酯化合物的方法，可以通过本发明的方法以高产率有效地制备高纯度的卡培他滨富马酸三烷基碳酸酯化合物作为中间体。

6. 发明授权

US08097706B2 Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein 失效
标题翻译：制备用于其中的卡培他滨和β-异头物富含三烷基碳酸酯化合物的方法
公开(公告)号：US08097706B2
公开(公告)日：2012-01-17
申请号：US12742367
申请日：2008-11-07
申请人： Jaeheon Lee , Gha-Seung Park , Weon Ki Yang , Jin Hee Kim , Cheol Hyun Park , Yong-Hoon An , Yoon Ju Lee , Young-Kil Chang , Gwan Sun Lee
发明人： Jaeheon Lee , Gha-Seung Park , Weon Ki Yang , Jin Hee Kim , Cheol Hyun Park , Yong-Hoon An , Yoon Ju Lee , Young-Kil Chang , Gwan Sun Lee
IPC分类号： C07G3/00 , C07G11/00 , C07H15/00 , C07H17/00 , C07H19/00
CPC分类号： C07D405/04 , C07H1/00 , C07H19/06 , Y02P20/55
摘要： The present invention relates to a method for preparing capecitabine and a method for preparing a β-anomer-rich trialkyl carbonate compound used therein, and a highly pure capecitabine can be efficiently prepared with a high yield by the method of the present invention using the β-anomer-rich trialkyl carbonate compound as an intermediate.
摘要翻译：本发明涉及一种制备卡培他滨的方法和一种制备其中使用的富含甘油的三烷基碳酸酯化合物的方法，可以通过本发明的方法以高产率有效地制备高纯度的卡培他滨富马酸三烷基碳酸酯化合物作为中间体。

7. 发明申请

US20120279505A1 TRACHEAL TUBE COMPRISING TRACHEA SEALING PORTION 审中-公开
标题翻译：包含TRACHEA密封件的TRACHEAL管
公开(公告)号：US20120279505A1
公开(公告)日：2012-11-08
申请号：US13478050
申请日：2012-05-22
申请人： Jin Hee Kim
发明人： Jin Hee Kim
IPC分类号： A61M16/04
CPC分类号： A61M16/04 , A61M16/0459 , A61M16/0479 , A61M16/0486
摘要： The present invention provides a tracheal tube comprising: a hollow tube inserted into the trachea; a first volume expansion portion for encompassing one side of the hollow tube; a second volume expansion portion positioned below the first volume expansion portion; a first conduit for expanding the first volume expansion portion and the second volume expansion portion; and a second conduit for supplying media for sealing to a trachea sealing portion positioned between the first volume expansion portion and the second volume expansion portion. The tracheal tube of the present invention can reduce the pressure of two cuffs which are the volume expansion portions, and can effectively improve sealing by supplying media to the trachea sealing portion positioned between the two cuffs. The tracheal tube of the present invention can reduce pulmonary aspiration and can thus considerably prevent ventilator-associated pneumonia (VAP).
摘要翻译：本发明提供一种气管管，包括：插入气管的中空管; 用于包围中空管的一侧的第一体积膨胀部分; 第二体积膨胀部分，位于所述第一体积膨胀部分的下方; 用于使所述第一体积膨胀部分和所述第二体积膨胀部分膨胀的第一导管; 以及第二导管，用于向定位在第一体积膨胀部分和第二体积膨胀部分之间的气管密封部分供给用于密封的介质。本发明的气管管可以减小作为体积膨胀部的两个袖带的压力，并且可以通过向位于两个袖口之间的气管密封部供给介质来有效地改善密封。本发明的气管管可以减少肺抽吸，因此可以显着地防止呼吸机相关性肺炎（VAP）。

8. 发明授权

US08101301B2 Lithium ion secondary battery 有权
标题翻译：锂离子二次电池
公开(公告)号：US08101301B2
公开(公告)日：2012-01-24
申请号：US13100919
申请日：2011-05-04
申请人： Won Chull Han , Chan Jung Kim , Jae Woong Kim , Jun Ho Kim , Jin Hee Kim , Ha Young Lee
发明人： Won Chull Han , Chan Jung Kim , Jae Woong Kim , Jun Ho Kim , Jin Hee Kim , Ha Young Lee
IPC分类号： H01M2/16
CPC分类号： H01M2/166 , H01M2/145 , H01M2/18 , H01M10/0525
摘要： A lithium ion secondary battery is provided. The lithium ion secondary battery generally comprises an electrode assembly, a container for accommodating the electrode assembly; and an electrolyte. The electrode assembly comprises two electrodes having opposite polarities and a separator. The separator comprises a porous membrane comprising clusters of ceramic particles. The porous membrane is formed by bonding the particle clusters with a binder. Each particle cluster is formed either by sintering or by dissolving and re-crystallizing all or a portion of the ceramic particles. The ceramic particles comprise a ceramic material having a band gap. Each particle cluster may have the shape of a grape bunch or a lamina, and may be formed by laminating scale or flake shaped ceramic particles.
摘要翻译：提供锂离子二次电池。锂离子二次电池通常包括电极组件，用于容纳电极组件的容器; 和电解质。电极组件包括具有相反极性的两个电极和分离器。分离器包括包含陶瓷颗粒簇的多孔膜。多孔膜通过将颗粒团与粘合剂结合而形成。每个颗粒簇通过烧结或通过溶解和重结晶全部或一部分陶瓷颗粒而形成。陶瓷颗粒包括具有带隙的陶瓷材料。每个颗粒簇可以具有葡萄束或层的形状，并且可以通过层压鳞片或片状陶瓷颗粒形成。

9. 发明授权

US07964311B2 Lithium ion secondary battery 有权
标题翻译：锂离子二次电池
公开(公告)号：US07964311B2
公开(公告)日：2011-06-21
申请号：US11283604
申请日：2005-11-17
申请人： Won Chull Han , Chan Jung Kim , Jae Woong Kim , Jun Ho Kim , Jin Hee Kim , Ha Young Lee
发明人： Won Chull Han , Chan Jung Kim , Jae Woong Kim , Jun Ho Kim , Jin Hee Kim , Ha Young Lee
IPC分类号： H01M2/16
CPC分类号： H01M2/166 , H01M2/145 , H01M2/18 , H01M10/0525
摘要： A lithium ion secondary battery is provided. The lithium ion secondary battery generally comprises an electrode assembly, a container for accommodating the electrode assembly; and an electrolyte. The electrode assembly comprises two electrodes having opposite polarities and a separator. The separator comprises a porous membrane comprising clusters of ceramic particles. The porous membrane is formed by bonding the particle clusters with a binder. Each particle cluster is formed either by sintering or by dissolving and re-crystallizing all or a portion of the ceramic particles. The ceramic particles comprise a ceramic material having a band gap. Each particle cluster may have the shape of a grape bunch or a lamina, and may be formed by laminating scale or flake shaped ceramic particles.
摘要翻译：提供锂离子二次电池。锂离子二次电池通常包括电极组件，用于容纳电极组件的容器; 和电解质。电极组件包括具有相反极性的两个电极和分离器。分离器包括包含陶瓷颗粒簇的多孔膜。多孔膜通过将颗粒团与粘合剂结合而形成。每个颗粒簇通过烧结或通过溶解和重结晶全部或一部分陶瓷颗粒而形成。陶瓷颗粒包括具有带隙的陶瓷材料。每个颗粒簇可以具有葡萄束或层的形状，并且可以通过层压鳞片或片状陶瓷颗粒形成。

10. 外观设计

USD610363S1 Reclining massage chair 有权
公开(公告)号：USD610363S1
公开(公告)日：2010-02-23
申请号：US29343407
申请日：2009-09-11
申请人： Byung Won Choi , Seok Ki Lee , Jin Hee Kim , Jae Yeon Jeon
设计人： Byung Won Choi , Seok Ki Lee , Jin Hee Kim , Jae Yeon Jeon

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